Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
2 Acetazolamide [1] Acetazolamide[2] Acetazolamide ,
Acetazolamide sodium 💬 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 67, 90, 115, 155, 222, 225, 230 💬
3 Amiloride [2] AMILORIDE; Amiloride Hydrochloride[2] Amiloride hydrochloride ,
Amiloride 💬 		[3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[5] 13, 67, 222, 225, 299 💬
4 Arginine [1] Arginine[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
5 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Atorvastatina[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
6 Chlorothiazide [1] Chlorothiazide[2] Chlorothiazide ,
Chlorothiazide sodium 💬 		[1] SLC12A3 💬 [1] Parathyroid hormone synthesis, secretion and action 💬[1] 225 💬
7 Desmopressin [2] Desmopressin; Desmopressin acetate[2] Desmopressin ,
Desmopressin acetate 💬 		[2] AVPR2,
F8 💬 		[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[8] 6, 22, 64, 72, 75, 223, 225, 288 💬
8 Fluconazole [2] Diflucan; FLUCONAZOLE[1] Fluconazole 💬 --[3] 67, 96, 225 💬
9 Hydrochlorothiazide [1] HYDROCHLOROTHIAZIDE[1] Hydrochlorothiazide 💬 [1] SLC12A3 💬 [1] Parathyroid hormone synthesis, secretion and action 💬[5] 13, 67, 222, 225, 235 💬
10 Indomethacin [2] INDOMETACIN; Indomethacin[2] Indomethacin ,
Indomethacin sodium 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
11 Magnesium [2] MAGNESIO; Magnesium---[23] 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
12 Metformin [4] Metformin; Metformin Hydrochloride; Metformina; Metformine[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
13 NDI-5001 [1] NDI-5001---[1] 225 💬
14 Omeprazole [3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
15 Riociguat [1] RIOCIGUAT[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299 💬
16 Sevoflurane [1] Sevoflurane[1] Sevoflurane 💬 --[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
17 Sildenafil [3] Sildenafil; SILDENAFIL CITRATE; SILDENAFILO[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
18 Spironolactone [1] Spironolactone[1] Spironolactone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
19 Tolvaptan [1] Tolvaptan[1] Tolvaptan 💬 [1] AVPR2 💬 [4] Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[5] 67, 72, 86, 222, 225 💬
20 Vasopressin [1] Vasopressin[1] Vasopressin 💬 [3] AVPR1A,
AVPR1B,
AVPR2 💬 		[6] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[2] 210, 225 💬
21 Water [1] Water[1] Water 💬 --[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬