Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
118F-AV-1451----[3] 5, 7, 127 💬
218F-RO6958948----[3] 5, 7, 127 💬
34-benzyl-2-naphtalen-1-yl-1,2,4-thiadiazolidine-3,5-dione----[1] 5 💬
49-CIS, 12-CIS-11,11-D2-LINOLEIC ACID ETHYL ESTER[1] Linoleic acid---[2] 2, 5 💬
5[18F] APN-1607----[1] 5 💬
6[18F]-PI2620----[1] 5 💬
7[18F]ABBV-964i----[1] 5 💬
8[18F]ABBV-965i----[1] 5 💬
9[18F]Florbetapir----[1] 5 💬
10[18F]MNI-815 (MNI-815)----[1] 5 💬
11[18F]MNI-952----[1] 5 💬
12[18F]MNI-958----[1] 5 💬
13[18F]T807 ([18F]MNI-777)----[2] 5, 6 💬
14[BIIB092]----[1] 5 💬
15[F18]-FDDNP----[1] 5 💬
16AADvac1----[1] 5 💬
17AB1010----[6] 2, 5, 6, 13, 46, 96 💬
18ABBV-8E12----[2] 5, 7 💬
19AL-108----[1] 5 💬
20Alpha-lipoic acid and L-acetyl carnitine[1] Lipoic acid[1] Thioctic acid 💬 --[1] 5 💬
21AMX0035----[3] 2, 5, 233 💬
22Anti-Parkinson medication----[5] 5, 6, 7, 8, 17 💬
23Antisense oligonucleotide----[1] 5 💬
24Apomorphine[1] Apomorphine[2] Apomorphine hydrochloride ,
Apomorphine 💬 		[2] DRD1,
DRD2 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
25ASK Nr. 21972----[2] 5, 6 💬
26Azilect----[3] 5, 6, 17 💬
27AZP2006 oral solution----[1] 5 💬
28Bepranemab[1] Bepranemab[1] Bepranemab 💬 [1] MAPT 💬 [4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 5 💬
29BIIB092----[3] 5, 7, 127 💬
30BMS-986168----[1] 5 💬
31BMS986168----[1] 5 💬
32BOTULINUM TOXIN TYPE A[1] Botulinum toxin type A[4] Botulinum toxin type A ,
OnabotulinumtoxinA ,
AbobotulinumtoxinA ,
Incobotulinumtoxin A 💬 		[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
33Brain PET scan----[3] 5, 7, 127 💬
34Coenzym Q10 Nanodispersion----[2] 5, 6 💬
35Coenzym Q10, Ubiquinon, Ubichinon----[2] 5, 6 💬
36Coenzyme Q10----[11] 2, 5, 6, 8, 10, 18, 49, 57, 107, 113, 193 💬
37CoQ10----[4] 5, 6, 8, 96 💬
38Creatine[1] Creatine---[18] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
39DaTSCAN----[3] 2, 5, 6 💬
40Davunetide[1] Davunetide[1] Davunetide 💬 --[3] 5, 7, 127 💬
41Davunetide (AL-108, NAP)[1] Davunetide[1] Davunetide 💬 --[3] 5, 7, 127 💬
42Deep Brain Stimulation----[5] 5, 6, 7, 8, 17 💬
43Diagnostic Test: 3 Tesla MRI without contrast medium----[3] 2, 5, 127 💬
44Diagnostic Test: 7T MRI scan----[3] 5, 7, 127 💬
45Diagnostic Test: [18F]-RO6958948----[6] 2, 5, 6, 7, 17, 127 💬
46Diagnostic Test: Blood withdrawal----[4] 5, 7, 8, 127 💬
47Diagnostic Test: Cerebrospinal fluid sampling (CSF)----[3] 2, 5, 127 💬
48Diagnostic Test: Clinical measures----[4] 5, 7, 8, 127 💬
49Diagnostic Test: CSF----[3] 5, 7, 127 💬
50Diagnostic Test: Elecsys (Roche) Abeta42, Ttau and Ptau----[6] 2, 5, 6, 7, 17, 127 💬
51Diagnostic Test: Flutemetamol F18 Injection[1] Flutemetamol---[6] 2, 5, 6, 7, 17, 127 💬
52Diagnostic Test: Lumipulse (Fujirebio) Abeta42, Ttau and Ptau----[6] 2, 5, 6, 7, 17, 127 💬
53Diagnostic Test: Neurological evaluation----[3] 2, 5, 127 💬
54Diagnostic Test: Neuropsychological assessment----[3] 5, 7, 127 💬
55Diagnostic Test: Neuropsychological evaluation----[3] 2, 5, 127 💬
56Donepezil[1] Donepezil[2] Donepezil hydrochloride ,
Donepezil 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[8] 5, 6, 13, 46, 124, 127, 156, 206 💬
57Droxidopa[1] Droxidopa[1] Droxidopa 💬 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
58Emeramide[1] Emeramide---[2] 5, 17 💬
59Exelon 1,5 mg Hartkapseln----[1] 5 💬
60Exelon 3,0 mg Hartkapseln----[1] 5 💬
61Exelon 6,0 mg Hartkapseln----[1] 5 💬
62F-18----[2] 5, 127 💬
63F-18 AV 1451----[2] 5, 127 💬
64Fasudil[1] Fasudil[2] Fasudil hydrochloride ,
Fasudil 💬 		[2] ROCK1,
ROCK2 💬 		[25] Adherens junction, Axon guidance, Cadherin signaling, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 2, 5, 6, 7, 51 💬
65Flortaucipir[1] Flortaucipir[1] Flortaucipir F 18 💬 [1] MAPT 💬 [4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127 💬
66Flortaucipir F18[1] Flortaucipir[1] Flortaucipir F 18 💬 [1] MAPT 💬 [4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127 💬
67Flutemetamol[1] Flutemetamol---[6] 2, 5, 6, 7, 17, 127 💬
68FNP-223----[1] 5 💬
69Fresh Frozen Plasma----[1] 5 💬
70GDNF & Synchro Med Infusion System----[1] 5 💬
71Genetic: Blood sample for genetic analysis----[3] 2, 5, 127 💬
72Gold[1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
73GV1001 0.56mg----[1] 5 💬
74GV1001 1.12mg----[1] 5 💬
75Hydrogen[1] Hydrogen---[8] 5, 6, 13, 17, 83, 97, 226, 238 💬
76Lead Candidate----[1] 5 💬
77Leucine[1] Leucine[1] Leucine 💬 --[13] 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
78Levodopa[1] Levodopa[1] Levodopa 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 5, 6, 17, 90, 120, 140, 164, 201 💬
79Linoleic acid[1] Linoleic acid---[4] 2, 5, 13, 299 💬
80Lipoic acid[1] Lipoic acid[1] Thioctic acid 💬 --[6] 2, 5, 13, 14, 20, 97 💬
81Lithium----[5] 2, 5, 6, 7, 8 💬
82LM11A-31----[1] 5 💬
83MASITINIB[1] Masitinib[1] Masitinib 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
84Masitinib 100mg[1] Masitinib[1] Masitinib 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 2, 5 💬
85Masitinib 200mg[1] Masitinib[1] Masitinib 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 2, 5 💬
86MASITINIB MESYLATE[1] Masitinib[1] Masitinib 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
87N1,N3-BIS(2-MERCAPTOETHYL) ISOPHTHALAMIDE----[2] 5, 17 💬
88NBMI----[2] 5, 17 💬
89Nicotinamide[1] Nicotinamide[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
90Nicotinamide riboside[2] Nicotinamide,
Nicotinamide riboside		[1] Niacinamide 💬 --[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
91Nitrogen[1] Nitrogen[1] Nitrogen 💬 --[6] 5, 6, 17, 171, 211, 299 💬
92NP031112----[1] 5 💬
93NP031112 600mg----[1] 5 💬
94NP031112 800mg----[1] 5 💬
95NT 101----[4] 5, 6, 7, 17 💬
96Other: 13C6 Leucine[1] Leucine[1] Leucine 💬 --[3] 5, 7, 127 💬
97Other: clinical measures of disease severity and progression----[3] 5, 6, 17 💬
98Other: CSF, blood and urine sampling----[3] 5, 6, 17 💬
99Other: NIO752----[1] 5 💬
100Pyruvate, creatine, niacinamide[1] Creatine---[1] 5 💬
101Raclopride[1] Raclopride---[4] 5, 6, 7, 17 💬
102Radiopharmaceuticals----[1] 5 💬
103Rasagilin----[2] 5, 6 💬
104Rasagiline[1] Rasagiline[3] Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
105RASAGILINE MESILATE[1] Rasagiline[3] Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[3] 2, 5, 6 💬
106RILUZOLE[1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
107RIVASTIGMINE[1] Rivastigmine[2] Rivastigmine tartrate ,
Rivastigmine 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[3] 5, 6, 13 💬
108RT001----[3] 2, 5, 121 💬
109Salsalate[1] Salsalate[1] Salsalate 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5 💬
110Single dose C2N-8E12----[1] 5 💬
111Stem cell therapy----[2] 5, 57 💬
112Sugar pill----[9] 5, 6, 49, 67, 70, 86, 120, 206, 210 💬
113Suvorexant[1] Suvorexant[1] Suvorexant 💬 [2] HCRTR1,
HCRTR2 💬 		[2] Hormone signaling, Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬
114THK-5351[1] THK-5351---[5] 5, 6, 7, 17, 127 💬
115THK5351----[4] 5, 6, 7, 17 💬
116Tideglusib[1] Tideglusib---[3] 2, 5, 113 💬
117Tolfenamic Acid[1] Tolfenamic acid[1] Tolfenamic acid 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5 💬
118TPI 287----[2] 5, 7 💬
119TPI 287 2 mg/m2----[2] 5, 7 💬
120TPI-287[1] TPI-287---[2] 5, 7 💬
121TPI-287 20 mg/m2[1] TPI-287---[2] 5, 7 💬
122TPI-287 6.3 mg/m2[1] TPI-287---[2] 5, 7 💬
123TPN-101, 100 mg/day----[1] 5 💬
124TPN-101, 200 mg/day----[1] 5 💬
125TPN-101, 400 mg/day----[3] 2, 5, 127 💬
126Trihexyphenidyl[1] Trihexyphenidyl[2] Trihexyphenidyl hydrochloride ,
Trihexyphenidyl 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6 💬
127Ubidecarenon----[2] 5, 6 💬
128UCB0107 (bepranemab)[1] Bepranemab[1] Bepranemab 💬 [1] MAPT 💬 [4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 5 💬
129Valproic Acid[1] Valproic acid[3] Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 3, 5, 26, 34, 65, 89, 90, 145, 222, 331 💬
130Vizamyl----[3] 5, 7, 127 💬
131Vizamyl (flutemetamol(F-18))[1] Flutemetamol---[3] 5, 7, 127 💬
132Water[1] Water[1] Water 💬 --[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬
133Xeomin----[7] 5, 6, 7, 13, 15, 17, 113 💬
134Zoledronic acid[1] Zoledronic acid[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
135Zoledronic Acid 5Mg/Bag 100Ml Inj[1] Zoledronic acid[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[3] 5, 6, 17 💬
136Zolpidem[1] Zolpidem[2] Zolpidem tartrate ,
Zolpidem 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬