Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
11.5 x 10^6 UC-MSC + CM----[1] 90 💬
2100 µg Brimonidine Tartrate Implant[1] Brimonidine[2] Brimonidine tartrate ,
Brimonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 90 💬
3100 µg KIO-301[1] KIO-301---[1] 90 💬
4200 µg Brimonidine Tartrate Implant[1] Brimonidine[2] Brimonidine tartrate ,
Brimonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 90 💬
5400 µg Brimonidine Tartrate Implant[1] Brimonidine[2] Brimonidine tartrate ,
Brimonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 90 💬
64D-125 IVT Injection----[1] 90 💬
75 x 10^6 UC-MSC + CM----[1] 90 💬
850 µg KIO-301[1] KIO-301---[1] 90 💬
95081----[1] 90 💬
109-cis beta-Carotene-rich extract of Dunaliella alga----[1] 90 💬
119715X----[1] 90 💬
129741X----[1] 90 💬
139742X----[1] 90 💬
14[Dual AAV8.MYO7A]----[2] 90, 303 💬
15[NA]----[34] 3, 6, 11, 13, 14, 19, 28, 35, 41, 46, 49, 50, 53, 57, 62, 63, 65, 75, 79, 85, 90, 96, 97, 98, 113, 127, 162, 195, 223, 229, 251, 294, 299, 302 💬
16[Prednisone][1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[5] 19, 66, 90, 300, 303 💬
17AAV2-REP1----[1] 90 💬
18AAV2/5-hPDE6B----[1] 90 💬
19AAV2/5-hRKp.RPGR----[1] 90 💬
20AAV5-HRKP.RPGR[1] Botaretigene sparoparvovec---[1] 90 💬
21AAV8-RPGR[1] Cotoretigene toliparvovec---[1] 90 💬
22AAVB-081----[2] 90, 303 💬
23ACDN-01----[2] 90, 301 💬
24ACE Retino----[1] 90 💬
25Acetate[1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
26Acetazolamide[1] Acetazolamide[2] Acetazolamide ,
Acetazolamide sodium 💬 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 67, 90, 115, 155, 222, 225, 230 💬
27Acetylcysteine[1] Acetylcysteine[1] Acetylcysteine 💬 --[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
28Acetylcysteine amide[2] Acetylcysteine,
Acetylcysteine amide		[1] Acetylcysteine 💬 --[3] 19, 90, 303 💬
29Adalimumab[1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
30Adeno-associated virus type 2 vector encoding Rab escort protein 1----[1] 90 💬
31Adeno-associated virus vector expressing a human RPGR gene----[1] 90 💬
32ADX-2191----[1] 90 💬
33Aflibercept[1] Aflibercept[1] Aflibercept 💬 [3] PGF,
VEGFA,
VEGFB 💬 		[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[2] 90, 166 💬
34AGN-151597----[1] 90 💬
35AGTC-501 (high dose and modified corticosteroid regimen)----[1] 90 💬
36AGTC-501 (high dose and standard corticosteroid regimen)----[1] 90 💬
37AGTC-501 (low dose and standard corticosteroid regimen)----[1] 90 💬
38Alga Dunaliella Bardawil----[1] 90 💬
39Alga Dunaliella Bardawil powder----[1] 90 💬
40Alga Dunaliella Bardawill----[1] 90 💬
41ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED----[1] 90 💬
42AlloRx----[8] 2, 13, 46, 51, 85, 90, 97, 226 💬
43Amino acids[1] Amino acids---[6] 6, 70, 90, 113, 240, 298 💬
44Antioxidants----[3] 90, 298, 310 💬
45Aprokam----[1] 90 💬
46BETAMETASONE----[1] 90 💬
47BETAMETASONE DOC----[1] 90 💬
48Betamethasone[1] Betamethasone[6] Betamethasone ,
Betamethasone sodium phosphate ,
Betamethasone valerate ,
Betamethasone acetate ,
Betamethasone dipropionate ,
Betamethasone benzoate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
49BIIB112----[1] 90 💬
50Blue light-absorbing sunglasses----[1] 90 💬
51BMMNCs----[1] 90 💬
52Botaretigene Sparoparvovec[1] Botaretigene sparoparvovec---[1] 90 💬
53Brimonidine[1] Brimonidine[2] Brimonidine tartrate ,
Brimonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90 💬
54Brimonidine tartrate[1] Brimonidine[2] Brimonidine tartrate ,
Brimonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90 💬
55Brimonidine Tartrate Posterior Segment Drug Delivery System (Brimo PS DDS) Applicator System[1] Brimonidine[2] Brimonidine tartrate ,
Brimonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 90 💬
56BS01----[1] 90 💬
57Calcium[1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
58Cannabis----[2] 13, 90 💬
59CARBIDOPA[1] Carbidopa[1] Carbidopa 💬 [1] DDC 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
60CD34+ bone marrow stem cells intravitreal----[1] 90 💬
61CEFAZOLINA----[1] 90 💬
62Cefazolina Qilu----[1] 90 💬
63CEFUROXIMA----[1] 90 💬
64Cholesterol[1] Cholesterol[1] Cholesterol 💬 --[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
65Ciliary Neurotrophic Factor Implant NT-501----[1] 90 💬
66Circadin 2 mg----[1] 90 💬
67CIRCADIN 2 mg comprimidos de liberación prolongada----[1] 90 💬
68CLORAMFENICOLO----[1] 90 💬
69Cloramfenicolo Fisiopharma----[1] 90 💬
70CLORAMFENICOLO FISIOPHARMA - 1 G/10 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO ENDOVENOSO 1 FLACONCINO POLVERE + 1 FIALA SOLVENTE DA 10 ML----[1] 90 💬
71CNS10-NPC implantation----[1] 90 💬
72CNTO 2476----[1] 90 💬
73Combination Product: Gene therapy: GS030-DP AND Medical device: GS030-MD[1] GS030-DP---[1] 90 💬
74Combination Product: PRP combined Magnovision----[1] 90 💬
75Compound thrombosis capsule sig: 1.5g/tid----[1] 90 💬
76Conditioned Medium (CM)----[1] 90 💬
77Continuous oxygen[1] Oxygen[1] Oxygen 💬 --[1] 90 💬
78Control----[8] 2, 6, 46, 51, 90, 97, 168, 299 💬
79COQUN----[1] 90 💬
80Cornstarch control----[1] 90 💬
81Cotoretigene Toliparvovec[1] Cotoretigene toliparvovec---[1] 90 💬
82CPK850----[1] 90 💬
83Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
84Cysteine[1] Cysteine[2] L-Cysteine ,
Cysteine hydrochloride 💬 		--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
85DESAMETASONE----[3] 28, 63, 90 💬
86Dexamethasone[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
87Dexamethasone injection[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 90 💬
88Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)----[2] 90, 301 💬
89Disulfiram[1] Disulfiram[1] Disulfiram 💬 [3] ALDH1B1,
ALDH2,
ALDH3A2 💬 		[13] Alcoholic liver disease, Arginine and proline metabolism, Ascorbate and aldarate metabolism, Fatty acid degradation, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Lysine degradation, Pantothenate and CoA biosynthesis, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[3] 46, 90, 301 💬
90Docosahexaenoic acid----[4] 49, 90, 240, 299 💬
91Dorzolamide[1] Dorzolamide[2] Dorzolamide hydrochloride ,
Dorzolamide 💬 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
92DSP-3077 Retinal Sheet Cohort 1----[1] 90 💬
93DSP-3077 Retinal Sheet Cohort 2----[1] 90 💬
94DSP-3077 Retinal Sheet Cohort 3----[1] 90 💬
95Dual AAV8.MYO7A----[2] 90, 303 💬
96Ducressa----[1] 90 💬
97EA-2353[1] EA-2353---[1] 90 💬
98Eylea----[2] 90, 166 💬
99Fluocinolone[1] Fluocinolone---[1] 90 💬
100Fluocinolone Acetonide[2] Fluocinolone,
Fluocinolone acetonide		[1] Fluocinolone acetonide 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 90 💬
101Gene Therapy Product-MCO-010----[2] 90, 301 💬
102Gene Therapy product:vMCO-I----[1] 90 💬
103Genetic: AAV2/5-RPGR----[1] 90 💬
104Genetic: AAV5-hRKp.RPGR----[1] 90 💬
105Genetic: AAV5-hRKp.RPGR Intermediate Dose----[1] 90 💬
106Genetic: AAV5-hRKp.RPGR Low Dose----[1] 90 💬
107Genetic: BIIB111----[1] 90 💬
108Genetic: BIIB112----[1] 90 💬
109Genetic: Blood and/or skin biopsy----[2] 90, 301 💬
110Genetic: FT-002----[1] 90 💬
111Genetic: genetic analysis----[8] 34, 85, 90, 93, 94, 96, 234, 265 💬
112Genetic: Genetic Testing----[5] 79, 89, 90, 158, 299 💬
113Genetic: RTx-015----[1] 90 💬
114Genetic: Sub-Retinal Administration of OCU400-301[1] OCU400---[1] 90 💬
115Genetic: UGX202 injection----[1] 90 💬
116Genetic: ZM-02 (high dose)----[1] 90 💬
117Genetic: ZM-02 (low dose)----[1] 90 💬
118Genetic: ZM-02 (selected dose)----[1] 90 💬
119Ginkgo biloba[1] Ginkgo biloba[1] Ginkgo 💬 --[4] 13, 18, 47, 90 💬
120Ginkgo biloba pills sig: 300mg/tid[1] Ginkgo biloba[1] Ginkgo 💬 --[1] 90 💬
121GMP compliant-BM-MSC derived sEVs----[1] 90 💬
122GS030-DP[1] GS030-DP---[1] 90 💬
123HORA-PDE6B (AAV2/5.hPDE6B)----[1] 90 💬
124HRPC----[1] 90 💬
125HRPC DP----[1] 90 💬
126Human Embryonic Stem Cell Derived Retinal Pigment Epithelium (RPE)----[1] 90 💬
127Human primary Retinal Pigment Epithelial (HuRPE) cells----[1] 90 💬
128Human retinal progenitor cells----[1] 90 💬
129Human Retinal Progenitor Cells Drug Product----[1] 90 💬
130Hydroxychloroquine[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
131Hydroxychloroquine higher dose[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[1] 90 💬
132Hydroxychloroquine lower dose[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[1] 90 💬
133Hyperbaric Oxygen Therapy[1] Oxygen[1] Oxygen 💬 --[2] 71, 90 💬
134IGT001----[1] 90 💬
135Iluvien----[1] 90 💬
136Injection of stem cells in sub-tenon space of eye for the management of retinitis pigmentosa----[1] 90 💬
137Injection of stem cells in suprachoroidal space of eye for the management of Retinitis Pigmentosa----[1] 90 💬
138Intravitreal Adalimumab[1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 90 💬
139Intravitreal autologous CD34+ cells----[1] 90 💬
140Intravitreal injection of Autologous bone marrow Stem Cell----[1] 90 💬
141Intravitreal injection of autologous bone marrow stem cells----[1] 90 💬
142Intravitreal Injection of Ultevursen[1] Ultevursen---[2] 90, 303 💬
143ISTEM-01----[1] 90 💬
144KENACORT----[2] 90, 96 💬
145KENACORT - 40 MG/ ML SOSPENSIONE INIETTABILE 3 FLACONCINI DA 1 ML----[1] 90 💬
146KIO-301[1] KIO-301---[1] 90 💬
147Lentiviral vector containing MYO7A gene----[2] 90, 303 💬
148Lentiviral vector containing the human MY07A gene----[2] 90, 303 💬
149Levodopa[1] Levodopa[1] Levodopa 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 5, 6, 17, 90, 120, 140, 164, 201 💬
150Levodopa-Carbidopa[2] Carbidopa,
Levodopa		[2] Levodopa ,
Carbidopa 💬 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[17] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[2] 6, 90 💬
151Lutein[1] Lutein---[3] 13, 90, 164 💬
152Lutein (10 or 30 mg/day) capsules[1] Lutein---[1] 90 💬
153Lycium Barbarum----[1] 90 💬
154Melatonin[1] Melatonin[1] Melatonin 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
155Minocycline[1] Minocycline[2] Minocycline hydrochloride ,
Minocycline 💬 		--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
156Minocycline 100mg[1] Minocycline[2] Minocycline hydrochloride ,
Minocycline 💬 		--[2] 13, 90 💬
157Minocycline 200mg[1] Minocycline[2] Minocycline hydrochloride ,
Minocycline 💬 		--[1] 90 💬
158N-Acetyl Cysteine (NAC)[1] Cysteine[2] L-Cysteine ,
Cysteine hydrochloride 💬 		--[1] 90 💬
159N-Acetylcysteine[1] Acetylcysteine[1] Acetylcysteine 💬 --[14] 6, 13, 19, 20, 21, 49, 58, 85, 90, 111, 164, 296, 299, 337 💬
160N-Acetylcysteine Amide[2] Acetylcysteine,
Acetylcysteine amide		[1] Acetylcysteine 💬 --[3] 19, 90, 303 💬
161NAC effervescent tablets----[1] 90 💬
162Nerve Growt Factor - 2.5S----[1] 90 💬
163Nerve Growth Factor[1] Nerve Growth Factor---[5] 2, 3, 18, 53, 90 💬
164Nilvadipine[1] Nilvadipine[1] Nilvadipine 💬 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 90 💬
165NL-FLVC-001----[1] 90 💬
166NPI-001----[2] 90, 303 💬
167NT-501----[2] 90, 303 💬
168Nutritional Supplement----[1] 90 💬
169OCU400[1] OCU400---[1] 90 💬
170OCU400 High Dose[1] OCU400---[1] 90 💬
171OCU400 Low Dose[1] OCU400---[1] 90 💬
172OCU400 Med Dose[1] OCU400---[1] 90 💬
173OCU400 Second Eye Dosing[1] OCU400---[1] 90 💬
174Omeprazole[1] Omeprazole[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
175OpCT-001----[3] 90, 301, 303 💬
176Oral disulfiram[1] Disulfiram[1] Disulfiram 💬 [3] ALDH1B1,
ALDH2,
ALDH3A2 💬 		[13] Alcoholic liver disease, Arginine and proline metabolism, Ascorbate and aldarate metabolism, Fatty acid degradation, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Lysine degradation, Pantothenate and CoA biosynthesis, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[2] 90, 301 💬
177Other: Mock injection----[1] 90 💬
178Other: No intervention (Follow-Up assessment)----[1] 90 💬
179Other: No intervention, will not receive any active study intervention----[2] 90, 303 💬
180Other: Observational----[1] 90 💬
181Other: Sham (no implant)----[1] 90 💬
182Other: Sham procedure----[1] 90 💬
183Other: Sham-procedure----[2] 90, 303 💬
184Other: Sham-procedure (dose cohort 1&2 only)----[2] 90, 303 💬
185Other: Standard of Care Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 90, 301 💬
186Other: Subconjunctival injection of saline----[1] 90 💬
187Other: Sugar pill----[1] 90 💬
188Other: Visual Acuity (VA)----[2] 90, 301 💬
189Oxygen[1] Oxygen[1] Oxygen 💬 --[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
190Phase 1a: OCT-980 Capsule----[1] 90 💬
191Phase 1b/2: OCT-980 Tablet----[1] 90 💬
192Pitavastatin[1] Pitavastatin[2] Pitavastatin calcium ,
Pitavastatin magnesium 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
193Platelet Rich Plasma[1] Platelet Rich Plasma---[6] 35, 46, 47, 70, 90, 269 💬
194Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
195PREDNISONE DOC GENERICI[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 90 💬
196Prescribe N-acetylcysteine tablets[1] Acetylcysteine[1] Acetylcysteine 💬 --[1] 90 💬
197PRP----[1] 90 💬
198QLT091001----[1] 90 💬
199QR-1123[1] QR-1123---[1] 90 💬
200QR-421a----[2] 90, 303 💬
201RAAV.hPDE6A vector Pharmaceutical Form: Concentrate for solution for injection----[1] 90 💬
202RAAV2tYF-GRK1-hRPGRco----[1] 90 💬
203RAAV2tYF-GRK1-RPGR----[1] 90 💬
204Recombinant adeno-associated viral vector serotype 2.7m8 containing the ChrimsonR-tdTomato gene----[1] 90 💬
205RECOMBINANT HUMAN NERVE GROWTH FACTOR (RHNGF)[1] Nerve Growth Factor---[1] 90 💬
206Retinal pigment epitheliums transplantation----[1] 90 💬
207RhNGF 180 µg/ml eye drops solution----[1] 90 💬
208RhNGF 60 µg/ml eye drops solution----[1] 90 💬
209RNA antisense oligonucleotide for intravitreal injection----[2] 90, 303 💬
210SAR421869[1] SAR421869---[2] 90, 303 💬
211Sham----[4] 90, 211, 301, 303 💬
212Sham Injection----[2] 90, 302 💬
213Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
214SPVN06----[2] 90, 301 💬
215Stem cell implantation----[1] 90 💬
216Stem Cell Transplantation----[14] 13, 19, 20, 46, 48, 51, 60, 62, 65, 90, 125, 164, 234, 326 💬
217Stem/progenitor cells transplantation----[2] 90, 301 💬
218Subretinal administration of rAAV2-VMD2-hMERTKRecombinant Adeno-Associated Virus----[1] 90 💬
219Subretinal injection of rAAV.hPDE6A----[1] 90 💬
220Subretinal injection of umbilical cord blood platelet-rich plasma (CB-PRP)----[1] 90 💬
221Subtenon Injection of Autologous Platelet-Rich Plasma----[1] 90 💬
222Subtenon injection of Wharton jelly derived mesenchymal stem cell exosomes----[1] 90 💬
223Subtenon injection of Wharton jelly derived mesenchymal stem cells----[1] 90 💬
224TBD----[5] 19, 86, 90, 276, 299 💬
225Timrepigene emparvovec[1] Timrepigene emparvovec---[1] 90 💬
226TOBRAMICINA E DESAMETASONE DOC Generici----[1] 90 💬
227TOBRAMICINA E DESAMETASONE DOC GENERICI -----[1] 90 💬
228Triamcinolone[1] Triamcinolone[4] Triamcinolone ,
Triamcinolone acetonide ,
Triamcinolone diacetate ,
Triamcinolone hexacetonide 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
229Twice-daily dosage with 0.5% cyclosporine-A eyedrops[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 90 💬
230UF-021----[1] 90 💬
231Ultevursen[1] Ultevursen---[2] 90, 303 💬
232Umbilical Cord Mesenchymal Stem Cell (UC-MSC)----[1] 90 💬
233Unoprostone[1] Unoprostone[2] Isopropyl unoprostone ,
Unoprostone 💬 		[1] PTGFR 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬[1] 90 💬
234UshStat----[2] 90, 303 💬
235UshStat (SAR421869)[1] SAR421869---[2] 90, 303 💬
236Valproic Acid[1] Valproic acid[3] Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 3, 5, 26, 34, 65, 89, 90, 145, 222, 331 💬
237Vehicle eye drops----[1] 90 💬
238VG901----[1] 90 💬
239Vitamin A[1] Vitamin A[2] Vitamin A oil ,
Vitamin A 💬 		[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[4] 13, 53, 90, 97 💬
240Vitamin AD sig: 1 tablet/tid----[1] 90 💬
241Vitamin B sig: 10mg/tid----[1] 90 💬
242Vitamin E[1] Vitamin E[1] Vitamin E 💬 --[12] 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
243VP-001----[1] 90 💬
244Wharton's jelly derived mesenchymal stem cell----[1] 90 💬
245ZAPROL*----[1] 90 💬
246ZM-02-H----[1] 90 💬
247ZM-02-L----[1] 90 💬
248ZM-02-S----[1] 90 💬
249Zuretinol Acetate[2] Acetate,
Zuretinol acetate		---[1] 90 💬
250ZVS203e----[1] 90 💬