Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetazolamide 💬[1] Acetazolamide[1] Acetazolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 67, 90, 115, 155, 222, 225, 230 💬
2 Acetazolamide sodium 💬[1] Acetazolamide[1] Acetazolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 67, 90, 115, 155, 222, 225, 230 💬
3 Acetylcysteine 💬[1] Acetylcysteine[4] Acetylcysteine; N acetyl cysteine; N-acetyl cysteine; N-acetylcysteine--[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
4 Adalimumab 💬[1] Adalimumab[1] Adalimumab[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
5 Aflibercept 💬[1] Aflibercept[1] Aflibercept[3] PGF,
VEGFA,
VEGFB 💬 		[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[2] 90, 166 💬
6 Betamethasone 💬[1] Betamethasone[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
7 Betamethasone acetate 💬[1] Betamethasone[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
8 Betamethasone benzoate 💬[1] Betamethasone[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
9 Betamethasone dipropionate 💬[1] Betamethasone[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
10 Betamethasone sodium phosphate 💬[1] Betamethasone[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
11 Betamethasone valerate 💬[1] Betamethasone[1] Betamethasone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
12 Brimonidine 💬[1] Brimonidine[2] Brimonidine; Brimonidine tartrate[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90 💬
13 Brimonidine tartrate 💬[1] Brimonidine[2] Brimonidine; Brimonidine tartrate[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90 💬
14 Carbidopa 💬[1] Carbidopa[1] Carbidopa[1] DDC 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
15 Cholesterol 💬[1] Cholesterol[1] Cholesterol--[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
16 Cyclosporine 💬[1] Cyclosporine[7] Ciclosporin; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; CYCLOSPORINE A[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
17 Cysteine hydrochloride 💬[1] Cysteine[2] Cysteine; Cysteine hydrochloride--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
18 Dexamethasone 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
19 Dexamethasone phosphate 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
20 Dexamethasone sodium phosphate 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
21 Disulfiram 💬[1] Disulfiram[1] Disulfiram[3] ALDH1B1,
ALDH2,
ALDH3A2 💬 		[13] Alcoholic liver disease, Arginine and proline metabolism, Ascorbate and aldarate metabolism, Fatty acid degradation, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Lysine degradation, Pantothenate and CoA biosynthesis, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[3] 46, 90, 301 💬
22 Divalproex sodium 💬[1] Valproic acid[3] Divalproex sodium; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
23 Dorzolamide 💬[1] Dorzolamide[1] Dorzolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
24 Dorzolamide hydrochloride 💬[1] Dorzolamide[1] Dorzolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
25 Fluocinolone acetonide 💬[1] Fluocinolone acetonide[1] Fluocinolone Acetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 90 💬
26 Ginkgo 💬[1] Ginkgo biloba[1] Ginkgo biloba--[4] 13, 18, 47, 90 💬
27 Hydroxychloroquine 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
28 Hydroxychloroquine sulfate 💬[1] Hydroxychloroquine[2] HYDROXYCHLOROQUINE; HYDROXYCHLOROQUINE SULFATE--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
29 Isopropyl unoprostone 💬[1] Unoprostone[1] Unoprostone[1] PTGFR 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬[1] 90 💬
30 L-Cysteine 💬[1] Cysteine[2] Cysteine; Cysteine hydrochloride--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
31 Levodopa 💬[1] Levodopa[2] L-DOPA; Levodopa[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 5, 6, 17, 90, 120, 140, 164, 201 💬
32 Melatonin 💬[1] Melatonin[1] Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
33 Minocycline 💬[1] Minocycline[2] Minocycline; MINOCYCLINE HYDROCHLORIDE--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
34 Minocycline hydrochloride 💬[1] Minocycline[2] Minocycline; MINOCYCLINE HYDROCHLORIDE--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
35 Nilvadipine 💬[1] Nilvadipine[1] Nilvadipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 90 💬
36 Omeprazole 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
37 Omeprazole magnesium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
38 Omeprazole sodium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
39 Oxygen 💬[1] Oxygen[1] Oxygen--[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
40 Pitavastatin calcium 💬[1] Pitavastatin[2] Pitavastatin; PITAVASTATIN CALCIUM[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
41 Pitavastatin magnesium 💬[1] Pitavastatin[2] Pitavastatin; PITAVASTATIN CALCIUM[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
42 Prednisone 💬[1] Prednisone[2] PREDNISONA; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
43 Sildenafil 💬[1] Sildenafil[3] Sildenafil; Sildenafil Citrate; SILDENAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
44 Sildenafil citrate 💬[1] Sildenafil[3] SILDENAFIL; SILDENAFIL CITRATE; SILDENAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
45 Triamcinolone 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone Acetonide; TRIAMCINOLONE HEXACETONIDE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
46 Triamcinolone acetonide 💬[1] Triamcinolone[3] Triamcinolone; TRIAMCINOLONE ACETONIDE; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
47 Triamcinolone diacetate 💬[1] Triamcinolone[3] TRIAMCINOLONE; Triamcinolone Acetonide; TRIAMCINOLONE HEXACETONIDE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
48 Triamcinolone hexacetonide 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone Acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
49 Unoprostone 💬[1] Unoprostone[1] Unoprostone[1] PTGFR 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬[1] 90 💬
50 Valproate sodium 💬[1] Valproic acid[3] Divalproex sodium; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
51 Valproic acid 💬[1] Valproic acid[3] Divalproex sodium; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
52 Vitamin A 💬[1] Vitamin A[1] Vitamin A[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[4] 13, 53, 90, 97 💬
53 Vitamin A oil 💬[1] Vitamin A[1] Vitamin A--[4] 13, 53, 90, 97 💬
54 Vitamin E 💬[1] Vitamin E[1] Vitamin E--[12] 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬