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Drug Description in Trials / DrugBank / KEGG DRUG

Search results

No.

KEGG DRUG

DrugBank

Drug (Description in trials)

KEGG GENES

KEGG PATHWAY

Disease ID

1

Lamotrigine 💬

[1] Lamotrigine

[1] LAMOTRIGINE

[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬

[7] 13, 34, 38, 113, 114, 115, 144 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
38	Stevens-Johnson syndrome
113	Muscular dystrophy
114	Non-dystrophic myotonia syndrome
115	Hereditary periodic paralysis
144	Lennox-Gastaut syndrome

2

Mexiletine 💬

[2] Mexiletine; Mexiletine hydrochloride

[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬

[6] 1, 2, 10, 113, 114, 115 💬

3

Mexiletine hydrochloride 💬

[2] Mexiletine; Mexiletine hydrochloride

[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬

[6] 1, 2, 10, 113, 114, 115 💬

4

Ranolazine 💬

-

-

[8] 2, 57, 58, 86, 96, 97, 113, 114 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
86	Pulmonary arterial hypertension
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
114	Non-dystrophic myotonia syndrome

5

Ranolazine hydrochloride 💬

-

-

[8] 2, 57, 58, 86, 96, 97, 113, 114 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
86	Pulmonary arterial hypertension
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
114	Non-dystrophic myotonia syndrome