Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Sacubitril 💬[1] Sacubitril[1] Sacubitril[1] MME 💬 [4] Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬[4] 28, 58, 210, 222 💬
2 Safinamide 💬[1] Safinamide[2] Safinamida; SAFINAMIDE[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
3 Safinamide mesylate 💬[1] Safinamide[2] Safinamida; SAFINAMIDE[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
4 Salicylic acid 💬[1] Salicylic acid[1] Salicylic acid--[1] 97 💬
5 Salmeterol 💬[1] Salmeterol[1] Salmeterol[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299 💬
6 Salmeterol xinafoate 💬[1] Salmeterol[1] Salmeterol[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299 💬
7 Salsalate 💬[1] Salsalate[1] Salsalate[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5 💬
8 Sapropterin 💬[1] Sapropterin[4] 6R-BH4; SAPROPTERIN; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin--[3] 86, 124, 240 💬
9 Sapropterin dihydrochloride 💬[1] Sapropterin[4] 6R-BH4; Sapropterin; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin--[3] 86, 124, 240 💬
10 Saquinavir 💬[1] Saquinavir[1] Saquinavir--[4] 86, 222, 223, 265 💬
11 Saquinavir mesylate 💬[1] Saquinavir[1] Saquinavir--[4] 86, 222, 223, 265 💬
12 Saracatinib 💬[1] Saracatinib[1] Saracatinib[2] ABL1,
SRC 💬 		[50] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Hormone signaling, Human cytomegalovirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272 💬
13 Sargramostim 💬[1] Sargramostim[1] Sargramostim[1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
14 Sarilumab 💬[1] Sarilumab[3] REGN88; SAR153191; Sarilumab[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[5] 41, 46, 84, 107, 271 💬
15 Sarizotan hydrochloride 💬[1] Sarizotan[2] Sarizotan; SARIZOTAN HYDROCHLORIDE[2] DRD2,
HTR1A 💬 		[12] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 156 💬
16 Saroglitazar 💬[1] Saroglitazar[2] Saroglitazar; SAROGLITAZAR MAGNESIUM[3] PPARA,
PPARD,
PPARG 💬 		[22] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Efferocytosis, Glucagon signaling pathway, Hepatitis C, Huntington disease, Insulin resistance, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Wnt signaling pathway, cAMP signaling pathway 💬[1] 93 💬
17 Saroglitazar magnesium 💬[1] Saroglitazar[2] Saroglitazar; SAROGLITAZAR MAGNESIUM[3] PPARA,
PPARD,
PPARG 💬 		[22] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Efferocytosis, Glucagon signaling pathway, Hepatitis C, Huntington disease, Insulin resistance, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Wnt signaling pathway, cAMP signaling pathway 💬[1] 93 💬
18 Satralizumab 💬[1] Satralizumab[1] Satralizumab[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 11, 13, 86, 113 💬
19 Saxagliptin 💬[1] Saxagliptin[1] Saxagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[1] 299 💬
20 Saxagliptin hydrochloride 💬[1] Saxagliptin[1] Saxagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[1] 299 💬
21 Scopolamine 💬[1] Scopolamine[1] Scopolamine[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 2 💬
22 Scopolamine hydrobromide 💬[1] Scopolamine[1] Scopolamine[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 2 💬
23 Sebelipase alfa 💬[1] Sebelipase alfa[3] SBC-102; Sebelipasa Alfa; Sebelipase Alfa[1] LIPA 💬 [4] Cholesterol metabolism, Efferocytosis, Lysosome biogenesis, Steroid biosynthesis 💬[1] 19 💬
24 Sebetralstat 💬[1] Sebetralstat[1] Sebetralstat[1] KLKB1 💬 [1] Complement and coagulation cascades 💬[1] 65 💬
25 Secukinumab 💬[1] Secukinumab[1] SECUKINUMAB[1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[9] 13, 37, 40, 41, 46, 107, 160, 269, 271 💬
26 Seladelpar 💬[1] Seladelpar[1] SELADELPAR[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
27 Seladelpar lysine 💬[1] Seladelpar[1] SELADELPAR[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
28 Selegiline 💬[1] Selegiline[1] SELEGILINE[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
29 Selegiline hydrochloride 💬[1] Selegiline[1] SELEGILINE[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
30 Selexipag 💬[1] Selexipag[1] Selexipag[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 47, 51, 70, 84, 86, 88 💬
31 Selinexor 💬[1] Selinexor[1] Selinexor[1] XPO1 💬 [5] Human T-cell leukemia virus 1 infection, Influenza A, Nucleocytoplasmic transport, Ribosome biogenesis in eukaryotes, Viral life cycle - HIV-1 💬[1] 28 💬
32 Selonsertib 💬[1] Selonsertib[1] Selonsertib[1] MAP3K5 💬 [19] Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬[1] 86 💬
33 Selumetinib 💬[1] Selumetinib[2] Selumetinib; Selumetinib Sulfate[2] MAP2K1,
MAP2K2 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cadherin signaling, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Efferocytosis, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 34 💬
34 Selumetinib sulfate 💬[1] Selumetinib[2] Selumetinib; Selumetinib Sulfate[2] MAP2K1,
MAP2K2 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cadherin signaling, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Efferocytosis, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 34 💬
35 Semaglutide 💬[1] Semaglutide[1] Semaglutide[1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 51, 84, 113, 299 💬
36 Senicapoc 💬[1] Senicapoc[1] Senicapoc[1] KCNN4 💬 [4] GnRH secretion, Insulin secretion, Protein digestion and absorption, Salivary secretion 💬[1] 85 💬
37 Sepiapterin 💬[1] Sepiapterin[1] Sepiapterin--[1] 240 💬
38 Seralutinib 💬[1] Seralutinib[1] Seralutinib[2] PDGFRA,
PDGFRB 💬 		[22] Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Focal adhesion, Gap junction, Glioma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 86 💬
39 Serine 💬[1] Serine[2] L-Serine; Serine--[5] 2, 6, 86, 96, 222 💬
40 Serlopitant 💬[1] Serlopitant[1] Serlopitant[1] TACR1 💬 [3] Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 36 💬
41 Sertraline 💬[1] Sertraline[1] Sertraline[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 158, 206 💬
42 Sertraline hydrochloride 💬[1] Sertraline[1] Sertraline[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 158, 206 💬
43 Sesame oil 💬[1] Sesame oil[1] Sesame oil--[1] 3 💬
44 Setmelanotide 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
45 Setmelanotide acetate 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
46 Setrusumab 💬[1] Setrusumab[1] SETRUSUMAB[1] SOST 💬 [2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274 💬
47 Sevasemten 💬[1] Sevasemten[1] Sevasemten[8] MYH1,
MYH13,
MYH15,
MYH2,
MYH3,
MYH4,
MYH7B,
MYH8 💬 		[2] Cytoskeleton in muscle cells, Motor proteins 💬[1] 113 💬
48 Sevelamer 💬[1] Sevelamer[1] Sevelamer--[2] 235, 238 💬
49 Sevelamer carbonate 💬[1] Sevelamer[1] Sevelamer--[2] 235, 238 💬
50 Sevelamer hydrochloride 💬[1] Sevelamer[1] Sevelamer--[2] 235, 238 💬
51 Sevoflurane 💬[1] Sevoflurane[1] Sevoflurane--[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
52 Sibeprenlimab 💬[1] Sibeprenlimab[1] Sibeprenlimab[1] TNFSF13 💬 [3] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Rheumatoid arthritis 💬[1] 66 💬
53 Sibofimloc 💬[1] Sibofimloc[1] Sibofimloc--[1] 96 💬
54 Sifalimumab 💬[1] Sifalimumab[1] Sifalimumab[13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬 		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49 💬
55 Sildenafil 💬[1] Sildenafil[3] Sildenafil; Sildenafil Citrate; SILDENAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
56 Sildenafil citrate 💬[1] Sildenafil[3] Sildenafil; Sildenafil Citrate; SILDENAFILO[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
57 Silodosin 💬[1] Silodosin[1] Silodosin[1] ADRA1A 💬 [9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13 💬
58 Siltuximab 💬[1] Siltuximab[1] SILTUXIMAB[1] IL6 💬 [49] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 28, 331 💬
59 Simethicone 💬[1] Simethicone[1] Simethicone--[2] 13, 96 💬
60 Simvastatin 💬[1] Simvastatin[2] Simvastatin; Simvastatine[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
61 Siplizumab 💬[1] Siplizumab[1] Siplizumab[1] CD2 💬 [3] Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage, IgSF CAM signaling 💬[2] 94, 95 💬
62 Siponimod 💬[1] Siponimod[1] Siponimod[2] S1PR1,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[2] 13, 50 💬
63 Siponimod fumarate 💬[1] Siponimod[1] Siponimod[2] S1PR1,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[2] 13, 50 💬
64 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
65 Sirukumab 💬[1] Sirukumab[1] Sirukumab[1] IL6 💬 [49] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 41, 46 💬
66 Sitagliptin 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[6] 6, 63, 75, 77, 233, 299 💬
67 Sitagliptin phosphate 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[6] 6, 63, 75, 77, 233, 299 💬
68 Sitagliptin phosphate 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[6] 6, 63, 75, 77, 233, 299 💬
69 Sitaxentan 💬[1] Sitaxentan[3] Sitaxentan; Sitaxentan sodium; Sitaxsentan[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
70 Sitaxentan sodium 💬[1] Sitaxentan[3] Sitaxentan; Sitaxentan sodium; Sitaxsentan[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
71 Sivelestat 💬[1] Sivelestat[1] Sivelestat[1] ELANE 💬 [4] Neutrophil extracellular trap formation, Phagocytosis, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬[3] 13, 85, 96 💬
72 Sobetirome 💬[1] Sobetirome[1] Sobetirome[1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 20 💬
73 Sodium acetate 💬[1] Sodium acetate[1] Sodium acetate--[2] 81, 251 💬
74 Sodium alginate 💬[1] Alginic acid[2] Alginic acid; Sodium alginate--[3] 51, 53, 299 💬
75 Sodium ascorbate 💬[1] Sodium ascorbate[1] SODIUM ASCORBATE--[1] 97 💬
76 Sodium benzoate 💬[1] Benzoic acid[1] Benzoic acid--[1] 51 💬
77 Sodium bicarbonate 💬[1] Sodium bicarbonate[2] SODIO BICARBONATO; Sodium Bicarbonate--[4] 67, 97, 226, 299 💬
78 Sodium butyrate 💬[1] Butyric Acid[3] Butyrate; Butyric Acid; Sodium Butyrate--[3] 46, 156, 222 💬
79 Sodium chloride 💬[1] Sodium chloride[3] NaCl; Sodium chloride; Sodium chloride solution--[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
80 Sodium citrate 💬[1] Sodium citrate[1] Sodium citrate--[4] 67, 214, 215, 235 💬
81 Sodium fluoride 💬[1] Sodium fluoride[1] Sodium fluoride--[1] 51 💬
82 Sodium iodide 💬[1] Sodium iodide[1] Sodium iodide--[1] 34 💬
83 Sodium iodide I 123 💬[1] Sodium iodide[1] Sodium iodide--[1] 34 💬
84 Sodium iodide I 125 💬[1] Sodium iodide[1] Sodium iodide--[1] 34 💬
85 Sodium lactate 💬[1] Lactic acid[1] Lactic acid--[3] 46, 265, 299 💬
86 Sodium nitrite 💬[1] Nitrous acid[1] SODIUM NITRITE--[2] 86, 299 💬
87 Sodium nitroprusside 💬[1] Nitroprusside[2] Nitroprusside; SODIUM NITROPRUSSIDE--[1] 51 💬
88 Sodium oxybate 💬[1] Sodium oxybate[1] Sodium Oxybate--[2] 6, 149 💬
89 Sodium phenylbutyrate 💬[1] Phenylbutyric acid[2] PHENYLBUTYRATE; Sodium phenylbutyrate--[5] 2, 3, 8, 18, 251 💬
90 Sodium propionate 💬[1] Propanoic acid[2] Propanoic acid; Sodium propionate--[3] 6, 97, 271 💬
91 Sodium propionate 💬[1] Propanoic acid[2] Propanoic acid; Sodium propionate--[3] 6, 97, 271 💬
92 Sodium salicylate 💬[1] Salicylic acid[1] Salicylic acid[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 97 💬
93 Sodium sulfate 💬[1] Sodium sulfate[4] ANHYDROUS SODIUM SULFATE; Sodium sulfate; SODIUM SULFATE ANHYDROUS; SODIUM SULPHATE ANHYDROUS--[2] 28, 97 💬
94 Sodium thiosulfate 💬[1] Thiosulfuric acid[2] Sodium thiosulfate; SODIUM THIOSULFATE PENTAHYDRATE--[3] 50, 51, 52 💬
95 Sofosbuvir 💬[1] Sofosbuvir[1] Sofosbuvir--[1] 19 💬
96 Solifenacin 💬[1] Solifenacin[2] Solifenacin; Solifenacin Succinate[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
97 Solifenacin succinate 💬[1] Solifenacin[2] Solifenacin; Solifenacin Succinate[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
98 Solriamfetol 💬[1] Solriamfetol[1] Solriamfetol[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13 💬
99 Solriamfetol hydrochloride 💬[1] Solriamfetol[1] Solriamfetol[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13 💬
100 Solrikitug 💬[1] Solrikitug[1] Solrikitug[1] CRLF2 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 98 💬
101 Somapacitan 💬[1] Somapacitan[1] Somapacitan[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 195 💬
102 Somatorelin 💬[1] Somatorelin[1] Somatorelin[1] GHRHR 💬 [3] Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬[1] 13 💬
103 Somatostatin 💬[1] Somatostatin[1] Somatostatin[5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 67, 77 💬
104 Somatropin 💬[1] Somatotropin[2] Somatotropin; Somatropin[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[3] 3, 65, 236 💬
105 Sonrotoclax 💬[1] Sonrotoclax[1] Sonrotoclax[1] BCL2 💬 [40] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬[1] 28 💬
106 Soquelitinib 💬[1] Soquelitinib[1] Soquelitinib[1] ITK 💬 [3] Chemokine signaling pathway, Leukocyte transendothelial migration, T cell receptor signaling pathway 💬[1] 65 💬
107 Sorafenib 💬[1] Sorafenib[1] Sorafenib[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 34, 86 💬
108 Sorafenib tosylate 💬[1] Sorafenib[1] Sorafenib[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 34, 86 💬
109 Sorbitol solution 💬[1] Sorbitol[2] D-SORBITOL; Sorbitol--[2] 10, 97 💬
110 Sotagliflozin 💬[1] Sotagliflozin[1] Sotagliflozin[1] SLC5A1 💬 [3] Bile secretion, Carbohydrate digestion and absorption, Mineral absorption 💬[2] 58, 84 💬
111 Sotatercept 💬[1] Sotatercept[1] SOTATERCEPT[1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[2] 86, 284 💬
112 Soticlestat 💬[1] Soticlestat[1] SOTICLESTAT[1] CYP46A1 💬 [1] Primary bile acid biosynthesis 💬[2] 140, 144 💬
113 Sotrastaurin 💬[1] Sotrastaurin[1] Sotrastaurin[4] PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬 		[30] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagosome formation, GnRH signaling pathway, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 97 💬
114 Sotrastaurin acetate 💬[1] Sotrastaurin[1] Sotrastaurin[4] PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬 		[30] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagosome formation, GnRH signaling pathway, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 97 💬
115 Sparsentan 💬[1] Sparsentan[1] SPARSENTAN[2] AGTR1,
EDNRA 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 66, 218, 222, 223 💬
116 Spesolimab 💬[1] Spesolimab[1] SPESOLIMAB[1] IL1RL2 💬 [1] Cytokine-cytokine receptor interaction 💬[5] 37, 96, 97, 160, 269 💬
117 Spironolactone 💬[1] Spironolactone[1] Spironolactone[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
118 Stanozolol 💬[1] Stanozolol[1] Stanozolol[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 60 💬
119 Stavudine 💬[1] Stavudine[1] Stavudine--[1] 265 💬
120 Stiripentol 💬[1] Stiripentol[1] Stiripentol--[2] 140, 234 💬
121 Sucralfate 💬[1] Sucralfate[1] Sucralfate--[1] 98 💬
122 Sucrose 💬[1] Sucrose[1] Sucrose--[4] 62, 96, 97, 127 💬
123 Sufentanil 💬[1] Sufentanil[1] Sufentanil[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 11, 22, 46, 70, 280 💬
124 Sufentanil citrate 💬[1] Sufentanil[1] Sufentanil[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 11, 22, 46, 70, 280 💬
125 Sugammadex sodium 💬[1] Sugammadex[1] Sugammadex--[1] 11 💬
126 Sulbactam 💬[1] Sulbactam[1] Sulbactam--[1] 299 💬
127 Sulbactam benzathine 💬[1] Sulbactam[1] Sulbactam--[1] 299 💬
128 Sulbactam sodium 💬[1] Sulbactam[1] Sulbactam--[1] 299 💬
129 Sulfadoxine 💬[1] Sulfadoxine[1] Sulfadoxine--[1] 65 💬
130 Sulfamethoxazole 💬[1] Sulfamethoxazole[2] SULFAMETHOXAZOLE; Sulphamethoxazole--[8] 35, 44, 49, 61, 85, 223, 296, 299 💬
131 Sulfasalazine 💬[1] Sulfasalazine[2] Sulfasalazine; Sulphasalazine--[7] 46, 49, 86, 94, 107, 270, 271 💬
132 Sulfur hexafluoride 💬[1] Sulfur hexafluoride[2] Sulfur hexafluoride; Sulphur hexafluoride--[3] 96, 97, 215 💬
133 Sulindac 💬[1] Sulindac[1] Sulindac[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206 💬
134 Sunflower oil 💬[1] Sunflower oil[1] Sunflower oil--[4] 13, 46, 79, 299 💬
135 Sunitinib 💬[1] Sunitinib[2] Sunitinib; Sunitinib malate[9] CSF1R,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬 		[38] Acute myeloid leukemia, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 28, 34 💬
136 Sunitinib malate 💬[1] Sunitinib[2] Sunitinib; Sunitinib malate[9] CSF1R,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬 		[38] Acute myeloid leukemia, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 28, 34 💬
137 Suplatast tosilate 💬[1] Suplatast[2] Suplatast; Suplatast tosilate--[2] 85, 226 💬
138 Susoctocog alfa 💬[1] Susoctocog alfa[1] Susoctocog alfa[1] F8 💬 [1] Complement and coagulation cascades 💬[1] 288 💬
139 Sutimlimab 💬[1] Sutimlimab[1] Sutimlimab[1] C1S 💬 [5] Complement and coagulation cascades, Coronavirus disease, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 61 💬
140 Suvecaltamide 💬[1] Suvecaltamide[1] Suvecaltamide[3] CACNA1G,
CACNA1H,
CACNA1I 💬 		[8] Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus 💬[1] 6 💬
141 Suvorexant 💬[1] Suvorexant[1] Suvorexant[2] HCRTR1,
HCRTR2 💬 		[2] Hormone signaling, Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬