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No.
KEGG DRUG
DrugBank
Drug (Description in trials)
KEGG GENES
KEGG PATHWAY
Disease ID
1
Carbon dioxide
1. Carbon dioxide
×
Name
Other Names
Carbon dioxide
Carbon dioxide (JP18/USP)
Carbon dioxide (TN)
CARBON DIOXIDE AIR
CARBON DIOXIDE AIR MIXTURE
CARBON DIOXIDE NITROGEN
CARBON DIOXIDE OXYGEN
CARBON DIOXIDE REFRIGERATED
💬
[1]
Carbon dioxide
Carbon dioxide
[1]
Carbon dioxide
Carbon dioxide
-
-
[2]
97
97
,
158
💬
1. Carbon dioxide
×
Disease ID
Name
97
Ulcerative colitis
158
Tuberous sclerosis
2
Tacrolimus
2. Tacrolimus
×
Name
Other Names
Tacrolimus
Tacrolimus (USP/INN)
Tacrolimus hydrate (JP18)
Prograf (TN)
Protopic (TN)
ASTAGRAF XL
ENVARSUS
💬
[1]
Tacrolimus
Tacrolimus
[2]
Prograf
Prograf
;
Tacrolimus
[5]
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
2. Tacrolimus
×
Name
Full Name
PPP3CA
protein phosphatase 3 catalytic subunit alpha
PPP3CB
protein phosphatase 3 catalytic subunit beta
PPP3CC
protein phosphatase 3 catalytic subunit gamma
PPP3R1
protein phosphatase 3 regulatory subunit B, alpha
PPP3R2
protein phosphatase 3 regulatory subunit B, beta
[33]
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
[33]
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
[34]
2
2
,
6
,
11
,
13
,
36
,
46
,
49
,
50
,
51
,
53
,
56
,
60
,
61
,
62
,
65
,
66
,
85
,
95
,
96
,
97
,
113
,
151
,
158
,
164
,
222
,
224
,
226
,
227
,
228
,
283
,
284
,
285
,
286
,
299
💬
[34]
2
,
6
,
11
,
13
,
36
,
46
,
49
,
50
,
51
,
53
,
56
,
60
,
61
,
62
,
65
,
66
,
85
,
95
,
96
,
97
,
113
,
151
,
158
,
16
...
2. Tacrolimus
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
11
Myasthenia gravis
13
Multiple sclerosis/Neuromyelitis optica
36
Epidermolysis bullosa
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
50
Dermatomyositis
51
Scleroderma
53
Sjogren syndrome
56
Behcet disease
60
Aplastic anemia
61
Autoimmune hemolytic anemia
62
Paroxysmal nocturnal hemoglobinuria
65
Primary immunodeficiency
66
IgA nephropathy
85
Idiopathic interstitial pneumonia
95
Autoimmune hepatitis
96
Crohn disease
97
Ulcerative colitis
113
Muscular dystrophy
151
Rasmussen encephalitis
158
Tuberous sclerosis
164
Oculocutaneous albinism
222
Primary nephrotic syndrome
224
Purpura nephritis
226
Interstitial cystitis with Hunners ulcer
227
Osler disease
228
Bronchiolitis obliterans
283
Acquired pure red cell aplasia
284
Diamond-Blackfan anemia
285
Fanconi anemia
286
Hereditary sideroblastic anemia
299
Cystic fibrosis
3
Aspirin
3. Aspirin
×
Name
Other Names
Aspirin
Aspirin (JP18/USP)
Aspalon (JAN)
Acetylsalicylic acid
Easprin (TN)
Durlaza (TN)
💬
[1]
Acetylsalicylic acid
Acetylsalicylic acid
[2]
ACETYLSALICYLIC ACID
ACETYLSALICYLIC ACID
;
Aspirin
[2]
PTGS1
PTGS1
,
PTGS2
💬
3. Aspirin
×
Name
Full Name
PTGS1
prostaglandin-endoperoxide synthase 1
PTGS2
prostaglandin-endoperoxide synthase 2
[23]
Alzheimer disease
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemical carcinogenesis - DNA adducts
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Platelet activation
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
VEGF signaling pathway
💬
[23]
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemi
...
[12]
13
13
,
22
,
46
,
49
,
51
,
58
,
64
,
86
,
113
,
158
,
210
,
231
💬
3. Aspirin
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
22
Moyamoya disease
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
58
Hypertrophic cardiomyopathy
64
Thrombotic thrombocytopenic purpura
86
Pulmonary arterial hypertension
113
Muscular dystrophy
158
Tuberous sclerosis
210
Single Ventricle
231
Alpha-1-antitrypsin deficiency
4
Calcitriol
4. Calcitriol
×
Name
Other Names
Calcitriol
Calcitriol (JAN/USP/INN)
Rocaltrol (TN)
VECTICAL
💬
[1]
Calcitriol
Calcitriol
[1]
Calcitriol
Calcitriol
[1]
VDR
VDR
💬
4. Calcitriol
×
Name
Full Name
VDR
vitamin D receptor
[5]
Chemical carcinogenesis - receptor activation
Chemical carcinogenesis - receptor activation
,
Endocrine and other factor-regulated calcium reabsorption
,
Mineral absorption
,
Parathyroid hormone synthesis, secretion and action
,
Tuberculosis
💬
[5]
Chemical carcinogenesis - receptor activation
,
Endocrine and other factor-regulated calcium reab
...
[9]
18
18
,
37
,
46
,
49
,
66
,
96
,
158
,
235
,
326
💬
4. Calcitriol
×
Disease ID
Name
18
Spinocerebellar degeneration
37
Generalised pustular psoriasis
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
66
IgA nephropathy
96
Crohn disease
158
Tuberous sclerosis
235
Hypoparathyroidism
326
Osteopetrosis
5
Bumetanide
5. Bumetanide
×
Name
Other Names
Bumetanide
Bumetanide (JP18/USP/INN)
Bumex (TN)
💬
[1]
Bumetanide
Bumetanide
[1]
Bumetanide
Bumetanide
[1]
SLC12A2
SLC12A2
💬
5. Bumetanide
×
Name
Full Name
SLC12A2
solute carrier family 12 member 2
[3]
Pancreatic secretion
Pancreatic secretion
,
Salivary secretion
,
Vibrio cholerae infection
💬
[2]
6
6
,
158
💬
5. Bumetanide
×
Disease ID
Name
6
Parkinson disease
158
Tuberous sclerosis
6
Doxycycline
6. Doxycycline
×
Name
Other Names
Doxycycline
Doxycycline (USP)
Doxycycline hydrate
Monodox (TN)
Oracea (TN)
Vibramycin (TN)
DOXYCYCLINE HYCLATE
DOXYCYCLINE MONOHYDRATE
💬
[1]
Doxycycline
Doxycycline
[4]
Doxycyclin
Doxycyclin
;
DOXYCYCLINE
;
DOXYCYCLINE HYCLATE
;
Doxycycline Tablets
-
-
[17]
13
13
,
23
,
28
,
34
,
46
,
84
,
85
,
89
,
96
,
97
,
158
,
161
,
162
,
167
,
227
,
280
,
299
💬
6. Doxycycline
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
23
Prion disease
28
Systemic amyloidosis
34
Neurofibromatosis
46
Malignant rheumatoid arthritis
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
89
Lymphangioleiomyomatosis
96
Crohn disease
97
Ulcerative colitis
158
Tuberous sclerosis
161
Familial benign chronic pemphigus
162
Pemphigoid
167
Marfan syndrome
227
Osler disease
280
Huge arteriovenous malformation with cervicofacial or limb lesion
299
Cystic fibrosis
7
Simvastatin
7. Simvastatin
×
Name
Other Names
Simvastatin
Simvastatin (JP18/USP/INN)
MK-733
Zocor (TN)
FLOLIPID
💬
[1]
Simvastatin
Simvastatin
[3]
Simvastatin
Simvastatin
;
Simvastatina
;
Simvastatine
[1]
HMGCR
HMGCR
💬
7. Simvastatin
×
Name
Full Name
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
[4]
AMPK signaling pathway
AMPK signaling pathway
,
Bile secretion
,
Metabolic pathways
,
Terpenoid backbone biosynthesis
💬
[21]
6
6
,
13
,
15
,
34
,
46
,
49
,
51
,
66
,
79
,
86
,
89
,
94
,
158
,
160
,
162
,
195
,
265
,
288
,
298
,
299
,
310
💬
7. Simvastatin
×
Disease ID
Name
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
15
Inclusion body myositis
34
Neurofibromatosis
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
66
IgA nephropathy
79
Homozygous familial hypercholesterolemia
86
Pulmonary arterial hypertension
89
Lymphangioleiomyomatosis
94
Primary sclerosing cholangitis
158
Tuberous sclerosis
160
Congenital ichthyosis
162
Pemphigoid
195
Noonan syndrome
265
Lipodystrophy
288
Autoimmune acquired coagulation factor deficiency
298
Hereditary pancreatitis
299
Cystic fibrosis
310
Congenital anomalies syndrome
8
Vigabatrin
8. Vigabatrin
×
Name
Other Names
Vigabatrin
Vigabatrin (JAN/USP/INN)
Sabril (TN)
VIGABATRIN FOR ORAL SOLUTION
VIGABATRIN FOR ORAL SOLUTION USP, 500 MG
VIGADRONE
💬
[1]
Vigabatrin
Vigabatrin
[2]
SABRIL
SABRIL
;
VIGABATRIN
[1]
ABAT
ABAT
💬
8. Vigabatrin
×
Name
Full Name
ABAT
4-aminobutyrate aminotransferase
[7]
Alanine, aspartate and glutamate metabolism
Alanine, aspartate and glutamate metabolism
,
Butanoate metabolism
,
GABAergic synapse
,
Metabolic pathways
,
Propanoate metabolism
,
Valine, leucine and isoleucine degradation
,
beta-Alanine metabolism
💬
[7]
Alanine, aspartate and glutamate metabolism
,
Butanoate metabolism
,
GABAergic synapse
,
Metabolic
...
[2]
145
145
,
158
💬
8. Vigabatrin
×
Disease ID
Name
145
West syndrome
158
Tuberous sclerosis
9
Sirolimus
9. Sirolimus
×
Name
Other Names
Sirolimus
Sirolimus (JAN/USAN/INN)
Rapamune (TN)
Rapamycin (TN)
FYARRO
HYFTOR
💬
[1]
Sirolimus
Sirolimus
[3]
Rapamune
Rapamune
;
Rapamycin
;
SIROLIMUS
[1]
MTOR
MTOR
💬
9. Sirolimus
×
Name
Full Name
MTOR
mechanistic target of rapamycin kinase
[51]
AMPK signaling pathway
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Apelin signaling pathway
,
Autophagy - animal
,
Autophagy - other
,
Breast cancer
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chemical carcinogenesis - receptor activation
,
Choline metabolism in cancer
,
Colorectal cancer
,
Diabetic cardiomyopathy
,
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Gastric cancer
,
Glioma
,
Growth hormone synthesis, secretion and action
,
HIF-1 signaling pathway
,
Hepatocellular carcinoma
,
Herpes simplex virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Huntington disease
,
Insulin resistance
,
Insulin signaling pathway
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
MicroRNAs in cancer
,
Neutrophil extracellular trap formation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Shigellosis
,
Spinocerebellar ataxia
,
Th17 cell differentiation
,
Thermogenesis
,
Thyroid hormone signaling pathway
,
Type II diabetes mellitus
,
mTOR signaling pathway
💬
[51]
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer dise
...
[40]
2
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
,
98
,
137
,
157
,
158
,
192
,
193
,
222
,
256
,
277
,
278
,
279
,
280
,
281
,
283
,
300
,
331
💬
[40]
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
, ...
9. Sirolimus
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
13
Multiple sclerosis/Neuromyelitis optica
15
Inclusion body myositis
17
Multiple system atrophy
19
Lysosomal storage disease
34
Neurofibromatosis
35
Pemphigus
36
Epidermolysis bullosa
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
53
Sjogren syndrome
60
Aplastic anemia
61
Autoimmune hemolytic anemia
62
Paroxysmal nocturnal hemoglobinuria
63
Idiopathic thrombocytopenic purpura
65
Primary immunodeficiency
66
IgA nephropathy
67
Polycystic kidney disease
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
89
Lymphangioleiomyomatosis
96
Crohn disease
98
Eosinophilic gastrointestinal disease
137
Focal cortical dysplasia
157
Sturge-Weber syndrome
158
Tuberous sclerosis
192
Cockayne syndrome
193
Prader-Willi syndrome
222
Primary nephrotic syndrome
256
Muscle glycogenosis
277
Lymphangiomatosis
278
Huge lymphatic malformation with cervicofacial lesion
279
Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
280
Huge arteriovenous malformation with cervicofacial or limb lesion
281
Klippel-Trenaunay-Weber syndrome
283
Acquired pure red cell aplasia
300
IgG4-related disease
331
Idiopathic multicentric castleman disease
10
Everolimus
10. Everolimus
×
Name
Other Names
Everolimus
Everolimus (JAN/USAN/INN)
Afinitor (TN)
Votubia (TN)
Zortress (TN)
💬
[1]
Everolimus
Everolimus
[4]
Afinitor
Afinitor
;
Certican
;
EVEROLIMUS
;
Votubia
[1]
MTOR
MTOR
💬
10. Everolimus
×
Name
Full Name
MTOR
mechanistic target of rapamycin kinase
[51]
AMPK signaling pathway
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Apelin signaling pathway
,
Autophagy - animal
,
Autophagy - other
,
Breast cancer
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chemical carcinogenesis - receptor activation
,
Choline metabolism in cancer
,
Colorectal cancer
,
Diabetic cardiomyopathy
,
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
Gastric cancer
,
Glioma
,
Growth hormone synthesis, secretion and action
,
HIF-1 signaling pathway
,
Hepatocellular carcinoma
,
Herpes simplex virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Huntington disease
,
Insulin resistance
,
Insulin signaling pathway
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
MicroRNAs in cancer
,
Neutrophil extracellular trap formation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Shigellosis
,
Spinocerebellar ataxia
,
Th17 cell differentiation
,
Thermogenesis
,
Thyroid hormone signaling pathway
,
Type II diabetes mellitus
,
mTOR signaling pathway
💬
[51]
AMPK signaling pathway
,
Acute myeloid leukemia
,
Adipocytokine signaling pathway
,
Alzheimer dise
...
[9]
34
34
,
67
,
89
,
96
,
137
,
157
,
158
,
228
,
277
💬
10. Everolimus
×
Disease ID
Name
34
Neurofibromatosis
67
Polycystic kidney disease
89
Lymphangioleiomyomatosis
96
Crohn disease
137
Focal cortical dysplasia
157
Sturge-Weber syndrome
158
Tuberous sclerosis
228
Bronchiolitis obliterans
277
Lymphangiomatosis