Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Adalimumab 💬[1] Adalimumab[1] Adalimumab[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[18] 19, 37, 40, 41, 46, 55, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
2 Amitriptyline 💬[1] Amitriptyline[2] Amitriptyline; Amitriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 97, 226, 299 💬
3 Amitriptyline hydrochloride 💬[1] Amitriptyline[2] Amitriptyline; Amitriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 97, 226, 299 💬
4 Atogepant 💬[1] Atogepant[1] Atogepant[1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
5 Botulinum toxin type A 💬[1] Botulinum toxin type A[5] Botulinum toxin A; Botulinum toxin type A; BTX-A; Incobotulinumtoxina; Onabotulinumtoxina[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 47, 51, 113, 149, 171, 226 💬
6 Bupivacaine 💬[1] Bupivacaine[2] Bupivacaine; Bupivacaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 46, 53, 70, 168, 226 💬
7 Bupivacaine hydrochloride 💬[1] Bupivacaine[2] Bupivacaine; Bupivacaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 46, 53, 70, 168, 226 💬
8 Cannabidiol 💬[1] Cannabidiol[1] Cannabidiol[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 19, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 271 💬
9 Capsaicin 💬[1] Capsaicin[1] Capsaicin[1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 2, 6, 86, 226 💬
10 Certolizumab pegol 💬[1] Certolizumab pegol[1] Certolizumab pegol[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[7] 37, 46, 49, 96, 107, 226, 271 💬
11 Cyclosporine 💬[1] Cyclosporine[6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
12 Dexmedetomidine 💬[1] Dexmedetomidine[3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
13 Dexmedetomidine hydrochloride 💬[1] Dexmedetomidine[3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
14 Dextrose 💬[1] Dextrose, unspecified form[2] Dextrose; Glucose--[12] 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
15 Dimethyl sulfoxide 💬[1] Dimethyl sulfoxide[2] Dimethyl sulfoxide; Dmso--[1] 226 💬
16 Eptinezumab 💬[1] Eptinezumab[1] Eptinezumab[1] CALC 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
17 Erenumab 💬[1] Erenumab[1] Erenumab[1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
18 Ferumoxytol 💬[1] Ferumoxytol[1] Ferumoxytol--[2] 13, 226 💬
19 Flavoxate 💬[1] Flavoxate[1] Flavoxate[16] PDE1,
PDE1,
PDE1,
PDE10,
PDE11,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE7,
PDE7,
PDE8,
PDE8 💬 		[17] Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
20 Flavoxate hydrochloride 💬[1] Flavoxate[1] Flavoxate[16] PDE1,
PDE1,
PDE1,
PDE10,
PDE11,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE7,
PDE7,
PDE8,
PDE8 💬 		[17] Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
21 Fospropofol disodium 💬[1] Fospropofol[0] [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬-
22 Fremanezumab 💬[1] Fremanezumab[1] Fremanezumab[1] CALC 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[2] 124, 226 💬
23 Gadobutrol 💬[1] Gadobutrol[1] Gadobutrol--[4] 13, 22, 46, 226 💬
24 Galcanezumab 💬[1] Galcanezumab[1] Galcanezumab[1] CALC 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
25 Gefapixant 💬[1] Gefapixant[1] Gefapixant[1] P2RX3 💬 [4] Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction 💬[2] 85, 226 💬
26 Gefapixant citrate 💬[1] Gefapixant[1] Gefapixant[1] P2RX3 💬 [4] Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction 💬[2] 85, 226 💬
27 Glucose, liquid 💬[1] Dextrose, unspecified form[2] Dextrose; Glucose--[12] 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
28 Glycine 💬[1] Glycine[1] Glycine--[6] 35, 60, 226, 247, 299, 340 💬
29 Heparin calcium 💬[1] Heparin[2] Heparin; Heparin sodium[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[9] 47, 60, 65, 70, 84, 107, 226, 280, 299 💬
30 Heparin sodium 💬[1] Heparin[2] Heparin; Heparin sodium[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[9] 47, 60, 65, 70, 84, 107, 226, 280, 299 💬
31 Hyaluronate sodium 💬[1] Hyaluronic acid[3] Hyaluronan; Hyaluronic acid; Sodium hyaluronate--[6] 46, 53, 70, 97, 226, 299 💬
32 Hyaluronic acid 💬[1] Hyaluronic acid[3] Hyaluronan; Hyaluronic acid; Sodium hyaluronate--[6] 46, 53, 70, 97, 226, 299 💬
33 Ketorolac 💬[1] Ketorolac[2] Ketorolac; Ketorolac tromethamine[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 70, 226 💬
34 Ketorolac tromethamine 💬[1] Ketorolac[2] Ketorolac; Ketorolac tromethamine[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 70, 226 💬
35 Lidocaine 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[10] 6, 13, 22, 46, 86, 107, 168, 226, 231, 256 💬
36 Lidocaine hydrochloride 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[10] 6, 13, 22, 46, 86, 107, 168, 226, 231, 256 💬
37 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[10] 6, 13, 22, 46, 86, 107, 168, 226, 231, 256 💬
38 Methenamine 💬[1] Methenamine[1] Methenamine--[1] 226 💬
39 Methenamine hippurate 💬[1] Methenamine[1] Methenamine--[1] 226 💬
40 Methenamine mandelate 💬[1] Methenamine[1] Methenamine--[1] 226 💬
41 Metoprolol 💬[1] Metoprolol[2] Metoprolol; Metoprolol succinate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 58, 113, 193 💬
42 Metoprolol fumarate 💬[1] Metoprolol[2] Metoprolol; Metoprolol succinate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 58, 113, 193 💬
43 Metoprolol succinate 💬[1] Metoprolol[2] Metoprolol; Metoprolol succinate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 58, 113, 193 💬
44 Metoprolol tartrate 💬[1] Metoprolol[2] Metoprolol; Metoprolol succinate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 58, 113, 193 💬
45 Mirabegron 💬[1] Mirabegron[1] Mirabegron[1] ADRB3 💬 [9] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
46 Monomethyl fumarate 💬[1] Monomethyl fumarate[1] Monomethyl fumarate--[1] 13 💬
47 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
48 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
49 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
50 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
51 Naloxone 💬[1] Naloxone[2] Naloxone hydrochloride; Naloxone hydrochloride dihydrate[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
52 Naloxone hydrochloride 💬[1] Naloxone[2] Naloxone hydrochloride; Naloxone hydrochloride dihydrate[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
53 Naloxone hydrochloride dihydrate 💬[1] Naloxone[2] Naloxone hydrochloride; Naloxone hydrochloride dihydrate[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
54 Naltrexone 💬[1] Naltrexone[2] Naltrexone; Naltrexone hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
55 Naltrexone hydrochloride 💬[1] Naltrexone[2] Naltrexone; Naltrexone hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
56 Nortriptyline 💬[1] Nortriptyline[2] Nortriptyline; Nortriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
57 Nortriptyline hydrochloride 💬[1] Nortriptyline[2] Nortriptyline; Nortriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
58 Omalizumab 💬[1] Omalizumab[1] Omalizumab[1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
59 Oxycodone 💬[1] Oxycodone[2] Oxycodone; Oxycodone hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 46, 70, 226, 298 💬
60 Oxycodone hydrochloride 💬[1] Oxycodone[2] Oxycodone; Oxycodone hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 46, 70, 226, 298 💬
61 Oxycodone terephthalate 💬[1] Oxycodone[2] Oxycodone; Oxycodone hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 46, 70, 226, 298 💬
62 Oxytocin 💬[1] Oxytocin[1] Oxytocin[1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[4] 127, 168, 193, 226 💬
63 Pentosan polysulfate sodium 💬[1] Pentosan polysulfate[2] Pentosan polysulfate; Pentosan polysulfate sodium--[2] 19, 26 💬
64 Prabotulinumtoxin A 💬[1] Botulinum toxin type A[5] Botulinum toxin A; Botulinum toxin type A; BTX-A; Incobotulinumtoxina; Onabotulinumtoxina[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 47, 51, 113, 149, 171, 226 💬
65 Propiverine 💬[1] Propiverine[1] Propiverine hydrochloride[9] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[44] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
66 Propiverine hydrochloride 💬[1] Propiverine[1] Propiverine hydrochloride[9] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[44] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
67 Rimegepant 💬[1] Rimegepant[1] Rimegepant[1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
68 Rimegepant sulfate 💬[1] Rimegepant[1] Rimegepant[1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
69 Sildenafil 💬[1] Sildenafil[3] Sildenafil; Sildenafil citrate; Sildenafilo[1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
70 Sildenafil citrate 💬[1] Sildenafil[3] Sildenafil; Sildenafil citrate; Sildenafilo[1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
71 Sodium bicarbonate 💬[1] Sodium bicarbonate[1] Sodium bicarbonate--[3] 97, 226, 299 💬
72 Sodium chloride 💬[1] Sodium chloride[2] Natriumchlorid; Sodium chloride--[20] 2, 11, 13, 14, 34, 41, 46, 51, 53, 60, 67, 70, 96, 97, 193, 214, 215, 227, 288, 299 💬
73 Suplatast tosilate 💬[1] Suplatast[2] Suplatast; Suplatast tosilate--[2] 85, 226 💬
74 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
75 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
76 Tanezumab 💬[1] Tanezumab[1] Tanezumab[1] NGFB 💬 [9] Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 226, 298 💬
77 Tramadol 💬[1] Tramadol[1] Tramadol[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 226 💬
78 Tramadol hydrochloride 💬[1] Tramadol[1] Tramadol[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 226 💬
79 Triamcinolone 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
80 Triamcinolone acetonide 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
81 Triamcinolone diacetate 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
82 Triamcinolone hexacetonide 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
83 Ubrogepant 💬[1] Ubrogepant[1] Ubrogepant[1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
84 Water 💬[1] Water[1] Water--[25] 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬