Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Betaine 💬[1] Betaine[1] Betaine--[4] 117, 201, 234, 337 💬
2 Betaine citrate 💬[1] Betaine[1] Betaine--[4] 117, 201, 234, 337 💬
3 Betaine hydrochloride 💬[1] Betaine[1] Betaine--[4] 117, 201, 234, 337 💬
4 Chenodiol 💬[1] Chenodeoxycholic acid[2] Chenodeoxycholic acid; Chenodiol[1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 96, 234, 263 💬
5 Cholic acid 💬[1] Cholic Acid[1] Cholic acid[1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 234, 265, 310 💬
6 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 96, 234 💬
7 Cyclosporine 💬[1] Cyclosporine[6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
8 Esomeprazole 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
9 Esomeprazole magnesium 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
10 Esomeprazole magnesium dihydrate 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
11 Esomeprazole sodium 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
12 Esomeprazole strontium 💬[1] Esomeprazole[3] Esomeprazole; Esomeprazole magnesium; Omeprazole[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
13 Hydroxychloroquine 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; Hydroxychloroquine sulfate--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
14 Hydroxychloroquine sulfate 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; Hydroxychloroquine sulfate--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
15 Lumasiran 💬[1] Lumasiran[1] Lumasiran[1] HAO 💬 [2] Glyoxylate and dicarboxylate metabolism, Peroxisome 💬[1] 234 💬
16 Lumasiran sodium 💬[1] Lumasiran[1] Lumasiran[1] HAO 💬 [2] Glyoxylate and dicarboxylate metabolism, Peroxisome 💬[1] 234 💬
17 Melphalan 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
18 Melphalan hydrochloride 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
19 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
20 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
21 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
22 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
23 Nedosiran sodium 💬[1] Nedosiran[1] Nedosiran[1] LDH 💬 [7] Central carbon metabolism in cancer, Cysteine and methionine metabolism, Glucagon signaling pathway, Glycolysis / Gluconeogenesis, HIF-1 signaling pathway, Propanoate metabolism, Pyruvate metabolism 💬[1] 234 💬
24 Pyridoxine 💬[1] Pyridoxine[1] Pyridoxine--[1] 320 💬
25 Pyridoxine hydrochloride 💬[1] Pyridoxine[1] Pyridoxine--[1] 320 💬
26 Stiripentol 💬[1] Stiripentol[1] Stiripentol--[2] 140, 234 💬
27 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
28 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
29 Ursodiol 💬[1] Ursodeoxycholic acid[3] Udca; Ursodeoxycholic acid; Ursodiol[1] NR1H4 💬 [1] Bile secretion 💬[13] 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬