Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acarbose 💬[1] Acarbose[1] Acarbose[5] AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬
[6] Carbohydrate digestion and absorption, Galactose metabolism, Lysosome biogenesis, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬[1] 298 💬
2 Acetylcysteine 💬[1] Acetylcysteine[4] ACETYLCYSTEINE; N acetyl cysteine; N-Acetyl cysteine; N-Acetylcysteine--[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
3 Alanine 💬[1] Alanine[2] Alanine; L-alanine--[8] 6, 13, 70, 94, 97, 251, 298, 299 💬
4 Amlodipine 💬[1] Amlodipine[1] Amlodipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
5 Amlodipine benzoate 💬[1] Amlodipine[1] AMLODIPINE[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
6 Amlodipine besylate 💬[1] Amlodipine[1] AMLODIPINE[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
7 Amlodipine maleate 💬[1] Amlodipine[1] Amlodipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
8 Ascorbic acid 💬[1] Ascorbic acid[2] Ascorbic acid; Vitamin C--[4] 10, 97, 206, 298 💬
9 Bupivacaine 💬[1] Bupivacaine[2] Bupivacaine; BUPIVACAINE HYDROCHLORIDE[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬
[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
10 Bupivacaine hydrochloride 💬[1] Bupivacaine[2] Bupivacaine; BUPIVACAINE HYDROCHLORIDE[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬
[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
11 Buprenorphine 💬[1] Buprenorphine[1] Buprenorphine[2] OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 298 💬
12 Buprenorphine hydrochloride 💬[1] Buprenorphine[1] Buprenorphine[2] OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 298 💬
13 Bupropion 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬
[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
14 Bupropion hydrobromide 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬
[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
15 Bupropion hydrochloride 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬
[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
16 Carbon monoxide 💬[1] Carbon monoxide[1] Carbon monoxide--[3] 85, 86, 298 💬
17 Cholecalciferol 💬[1] Cholecalciferol[4] Cholecalciferol; COLECALCIFEROL; Vitamin D-3; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[10] 13, 19, 34, 46, 49, 96, 97, 222, 298, 299 💬
18 Diazepam 💬[1] Diazepam[1] Diazepam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 46, 155, 298 💬
19 Dipyrone 💬[1] Metamizole[1] Metamizole--[1] 298 💬
20 Dipyrone 💬[1] Metamizole[1] Metamizole--[1] 298 💬
21 Dronabinol 💬[1] Dronabinol[3] DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; Tetrahydrocannabinol[2] CNR1,
CNR2 💬
[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[5] 2, 13, 46, 271, 298 💬
22 Empagliflozin 💬[1] Empagliflozin[1] Empagliflozin--[17] 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
23 Esomeprazole 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
24 Esomeprazole magnesium 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
25 Esomeprazole magnesium dihydrate 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
26 Esomeprazole sodium 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
27 Esomeprazole strontium 💬[1] Esomeprazole[3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
28 Etanercept 💬[1] Etanercept[1] Etanercept[2] LTA,
TNF 💬
[66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
29 Fentanyl 💬[1] Fentanyl[1] FENTANYL[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 46, 70, 97, 215, 231, 298 💬
30 Fentanyl citrate 💬[1] Fentanyl[1] Fentanyl[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 46, 70, 97, 215, 231, 298 💬
31 Fentanyl hydrochloride 💬[1] Fentanyl[1] Fentanyl[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 46, 70, 97, 215, 231, 298 💬
32 Gabapentin 💬[1] Gabapentin[3] Gabapentin; GABAPENTINA; Gabapentine[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬
[10] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[7] 6, 13, 18, 19, 70, 226, 298 💬
33 Hydroxychloroquine 💬[1] Hydroxychloroquine[2] HYDROXYCHLOROQUINE; Hydroxychloroquine Sulfate--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
34 Hydroxychloroquine sulfate 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
35 Indomethacin 💬[1] Indomethacin[2] INDOMETACIN; Indomethacin[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
36 Indomethacin sodium 💬[1] Indomethacin[2] INDOMETACIN; Indomethacin[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
37 Ivacaftor 💬[1] Ivacaftor[1] Ivacaftor[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[3] 298, 299, 340 💬
38 Lacosamide 💬[1] Lacosamide[1] Lacosamide[2] SCN3A,
SCN9A 💬
[1] Taste transduction 💬[4] 2, 46, 149, 298 💬
39 Lanreotide acetate 💬[1] Lanreotide[3] LANREOTIDA; Lanreotide; LANREOTIDE ACETATE[2] SSTR2,
SSTR5 💬
[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 67, 73, 77, 85, 298 💬
40 Lidocaine 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬
[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
41 Lidocaine hydrochloride 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬
[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
42 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine[2] Lidocaine; Lidocaine hydrochloride[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬
[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
43 Magnesium L-aspartate 💬[1] Magnesium aspartate[1] Magnesium aspartate--[1] 298 💬
44 Metamizole 💬[1] Metamizole[1] Metamizole--[1] 298 💬
45 Metformin 💬[1] Metformin[4] METFORMIN; Metformin Hydrochloride; METFORMINA; Metformine[2] PRKAA1,
PRKAA2 💬
[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
46 Metformin hydrochloride 💬[1] Metformin[4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬
[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
47 Methionine 💬[1] Methionine[2] L-methionine; Methionine--[9] 34, 75, 84, 93, 94, 229, 298, 300, 337 💬
48 Midazolam 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
49 Midazolam hydrochloride 💬[1] Midazolam[1] MIDAZOLAM[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
50 Midazolam maleate 💬[1] Midazolam[1] MIDAZOLAM[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
51 Morphine 💬[1] Morphine[3] Morphine; Morphine hydrochloride; Morphine Sulfate[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
52 Morphine hydrochloride hydrate 💬[1] Morphine[3] Morphine; Morphine hydrochloride; MORPHINE SULFATE[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
53 Morphine sulfate 💬[1] Morphine[3] Morphine; Morphine hydrochloride; Morphine Sulfate[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
54 Morphine tartrate 💬[1] Morphine[3] Morphine; Morphine hydrochloride; Morphine Sulfate[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298 💬
55 Omeprazole 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
56 Omeprazole magnesium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
57 Omeprazole sodium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
58 Oxycodone 💬[1] Oxycodone[2] OXYCODONE; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬
[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298 💬
59 Oxycodone hydrochloride 💬[1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬
[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298 💬
60 Oxycodone terephthalate 💬[1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬
[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298 💬
61 Oxygen 💬[1] Oxygen[1] Oxygen--[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
62 Pancreatin 💬[1] Pancrelipase[3] PANCREATIN; Pancrelipase; ZENPEP--[4] 96, 97, 298, 299 💬
63 Pancrelipase 💬[1] Pancrelipase[3] PANCREATIN; Pancrelipase; ZENPEP--[4] 96, 97, 298, 299 💬
64 Paricalcitol 💬[1] Paricalcitol[1] Paricalcitol[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
65 Pentoxifylline 💬[1] Pentoxifylline[1] Pentoxifylline--[13] 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
66 Perflubutane 💬[1] Perflubutane[1] Perflubutane--[2] 298, 300 💬
67 Pinaverium bromide 💬[1] Pinaverium[2] Pinaverium; Pinaverium bromide[1] CACNA1S 💬 [27] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Cardiac muscle contraction, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, GABAergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 298 💬
68 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
69 Pioglitazone hydrochloride 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
70 Pregabalin 💬[1] Pregabalin[1] Pregabalin[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬
[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298 💬
71 Proglumide 💬[1] Proglumide[1] Proglumide[1] CCKBR 💬 [4] Calcium signaling pathway, Gastric acid secretion, Hormone signaling, Neuroactive ligand-receptor interaction 💬[1] 298 💬
72 Reparixin 💬[1] Reparixin[1] Reparixin[2] CXCR1,
CXCR2 💬
[7] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 298, 299 💬
73 Simvastatin 💬[1] Simvastatin[2] Simvastatin; Simvastatine[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
74 Sodium chloride 💬[1] Sodium chloride[3] NaCl; Sodium chloride; Sodium Chloride solution--[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
75 Tanezumab 💬[1] Tanezumab[1] Tanezumab[1] NGF 💬 [9] Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 226, 298 💬
76 Thalidomide 💬[1] Thalidomide[1] Thalidomide[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
77 Tocilizumab 💬[1] Tocilizumab[2] BAT1806; Tocilizumab[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
78 Tocopherol 💬[1] Tocopherol[1] Tocopherol--[7] 13, 49, 71, 206, 215, 257, 298 💬
79 Triamcinolone 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone Acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
80 Triamcinolone acetonide 💬[1] Triamcinolone[3] Triamcinolone; TRIAMCINOLONE ACETONIDE; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
81 Triamcinolone diacetate 💬[1] Triamcinolone[3] TRIAMCINOLONE; Triamcinolone Acetonide; TRIAMCINOLONE HEXACETONIDE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
82 Triamcinolone hexacetonide 💬[1] Triamcinolone[3] Triamcinolone; TRIAMCINOLONE ACETONIDE; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
83 Varenicline 💬[1] Varenicline[2] Varenicline; VARENICLINE TARTRATE[2] CHRNA4,
CHRNB2 💬
[5] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[4] 6, 18, 53, 298 💬
84 Varenicline tartrate 💬[1] Varenicline[2] Varenicline; VARENICLINE TARTRATE[2] CHRNA4,
CHRNB2 💬
[5] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[4] 6, 18, 53, 298 💬