Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Dalfampridine 💬[1] Dalfampridine[5] 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[4] 3, 4, 13, 14 💬
2 Dexmedetomidine 💬[1] Dexmedetomidine[3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
3 Dexmedetomidine hydrochloride 💬[1] Dexmedetomidine[3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
4 Esketamine 💬[1] Esketamine[3] Esketamine; Esketamine hydrochloride; Ketamine[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 4, 6, 70, 96, 97, 156 💬
5 Esketamine hydrochloride 💬[1] Esketamine[3] Esketamine; Esketamine hydrochloride; Ketamine[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 4, 6, 70, 96, 97, 156 💬
6 Levetiracetam 💬[1] Levetiracetam[1] Levetiracetam[1] SV2 💬 [1] ECM-receptor interaction 💬[7] 2, 4, 6, 13, 34, 149, 307 💬
7 Pyrimethamine 💬[1] Pyrimethamine[1] Pyrimethamine--[4] 2, 4, 19, 65 💬