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KEGG DRUG

Search results

No.

KEGG DRUG

DrugBank

Drug (Description in trials)

KEGG GENES

KEGG PATHWAY

Disease ID

Adomiparin 💬

[1] Enoxaparin

[2] Enoxaparin; Enoxaparin Sodium

[1] SERPINC1 💬

[1] Complement and coagulation cascades 💬

[6] 46, 48, 71, 222, 223, 327 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
71	Idiopathic osteonecrosis of the femoral head
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
327	Idiopathic thrombosis

Anifrolumab 💬

[1] Anifrolumab

[2] IFNAR1,
IFNAR2 💬

[18] Coronavirus disease, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬

[6] 46, 48, 49, 50, 51, 53 💬

Apixaban 💬

[1] Apixaban

[1] F10 💬

[1] Complement and coagulation cascades 💬

[6] 48, 96, 97, 222, 223, 279 💬

Disease ID	Name
48	Primary antiphospholipid syndrome
96	Crohn disease
97	Ulcerative colitis
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion

Belimumab 💬

[1] Belimumab

[1] TNFSF13B 💬

[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬

[17] 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
43	Microscopic polyangiitis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
95	Autoimmune hepatitis
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
296	Biliary atresia
300	IgG4-related disease

Certolizumab pegol 💬

[1] Certolizumab pegol

[1] TNF 💬

[10] 37, 40, 46, 48, 49, 96, 97, 107, 226, 271 💬

Disease ID	Name
37	Generalised pustular psoriasis
40	Takayasu arteritis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
226	Interstitial cystitis with Hunners ulcer
271	Ankylosing spondylitis

Cilostazol 💬

[1] Cilostazol

[3] PDE3A,
PDE3B,
TBXA2R 💬

[13] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[7] 6, 13, 46, 48, 51, 70, 124 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
51	Scleroderma
70	Spinal stenosis
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

Crovalimab 💬

[1] Crovalimab

[1] C5 💬

[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬

[3] 48, 62, 109 💬

Danaparoid sodium 💬

[1] Danaparoid

[1] SERPINC1 💬

[1] Complement and coagulation cascades 💬

[1] 48 💬

Daratumumab 💬

[1] Daratumumab

[1] DARATUMUMAB

[1] CD38 💬

[6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬

[13] 13, 16, 28, 39, 46, 48, 49, 60, 63, 222, 223, 288, 331 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
16	Crow-Fukase syndrome
28	Systemic amyloidosis
39	Toxic epidermal necrolysis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
288	Autoimmune acquired coagulation factor deficiency
331	Idiopathic multicentric castleman disease

Efalizumab 💬

[1] Efalizumab

[1] EFALIZUMAB

[1] ITGAL 💬

[14] Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, IgSF CAM signaling, Integrin signaling, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬

[10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
37	Generalised pustular psoriasis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
53	Sjogren syndrome
61	Autoimmune hemolytic anemia
95	Autoimmune hepatitis
96	Crohn disease
221	Anti-glomerular basement membrane disease

Enoxaparin sodium 💬

[1] Enoxaparin

[2] ENOXAPARIN; Enoxaparin Sodium

[1] SERPINC1 💬

[1] Complement and coagulation cascades 💬

[6] 46, 48, 71, 222, 223, 327 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
71	Idiopathic osteonecrosis of the femoral head
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
327	Idiopathic thrombosis

Fluvastatin 💬

[1] Fluvastatin

[1] HMGCR 💬

[3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬

[4] 48, 79, 218, 222 💬

Fluvastatin sodium 💬

[1] Fluvastatin

[1] HMGCR 💬

[3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬

[4] 48, 79, 218, 222 💬

Heparin calcium 💬

[1] Heparin

[2] Heparin; Heparin Sodium

[1] SERPINC1 💬

[1] Complement and coagulation cascades 💬

[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬

Disease ID	Name
47	Buerger disease
48	Primary antiphospholipid syndrome
60	Aplastic anemia
65	Primary immunodeficiency
70	Spinal stenosis
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
107	Juvenile idiopathic arthritis
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
280	Huge arteriovenous malformation with cervicofacial or limb lesion
299	Cystic fibrosis
316	Carnitine cycle disorder
317	Trifunctional protein deficiency
344	Very long-chain acyl-CoA dehydrogenase deficiency

Heparin sodium

💬

[1] Heparin

[2] Heparin; HEPARIN SODIUM

[1] SERPINC1 💬

[1] Complement and coagulation cascades 💬

[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬

Disease ID	Name
47	Buerger disease
48	Primary antiphospholipid syndrome
60	Aplastic anemia
65	Primary immunodeficiency
70	Spinal stenosis
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
107	Juvenile idiopathic arthritis
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
280	Huge arteriovenous malformation with cervicofacial or limb lesion
299	Cystic fibrosis
316	Carnitine cycle disorder
317	Trifunctional protein deficiency
344	Very long-chain acyl-CoA dehydrogenase deficiency

Hydroxychloroquine 💬

[1] Hydroxychloroquine

[2] Hydroxychloroquine; Hydroxychloroquine sulfate

[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
41	Giant cell arteritis
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
53	Sjogren syndrome
56	Behcet disease
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
84	Sarcoidosis
89	Lymphangioleiomyomatosis
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
254	Porphyria
271	Ankylosing spondylitis
298	Hereditary pancreatitis
299	Cystic fibrosis

Hydroxychloroquine sulfate 💬

[1] Hydroxychloroquine

[2] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE

[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
41	Giant cell arteritis
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
53	Sjogren syndrome
56	Behcet disease
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
84	Sarcoidosis
89	Lymphangioleiomyomatosis
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
254	Porphyria
271	Ankylosing spondylitis
298	Hereditary pancreatitis
299	Cystic fibrosis

Prednisone 💬

[1] Prednisone

[2] PREDNISONA; Prednisone

[1] NR3C1 💬

[1] Neuroactive ligand-receptor interaction 💬

[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
18	Spinocerebellar degeneration
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
35	Pemphigus
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
145	West syndrome
162	Pemphigoid
164	Oculocutaneous albinism
205	Fragile X syndrome related disease
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
228	Bronchiolitis obliterans
251	Urea cycle disorder
269	Pyogenic arthritis
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
299	Cystic fibrosis
300	IgG4-related disease
303	Usher syndrome
307	Canavan disease
331	Idiopathic multicentric castleman disease

Rituximab 💬

[1] Rituximab

[1] MS4A1 💬

[1] Hematopoietic cell lineage 💬

[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
52	Mixed connective tissue disease
53	Sjogren syndrome
55	Relapsing polychondritis
56	Behcet disease
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
83	Addison disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
96	Crohn disease
97	Ulcerative colitis
162	Pemphigoid
172	Hypophosphatasia
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
229	Autoimmune pulmonary alveolar proteinosis
256	Muscle glycogenosis
271	Ankylosing spondylitis
274	Osteogenesis Imperfecta
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
296	Biliary atresia
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

Rivaroxaban 💬

[1] Rivaroxaban

[1] F10 💬

[1] Complement and coagulation cascades 💬

[10] 46, 48, 49, 56, 58, 75, 91, 210, 222, 271 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
56	Behcet disease
58	Hypertrophic cardiomyopathy
75	Cushing disease
91	Budd-Chiari syndrome
210	Single Ventricle
222	Primary nephrotic syndrome
271	Ankylosing spondylitis

Sirolimus 💬

[1] Sirolimus

[2] Rapamycin; Sirolimus

[1] MTOR 💬

[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
17	Multiple system atrophy
19	Lysosomal storage disease
21	Mitochondrial disease
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
51	Scleroderma
54	Adult still disease
57	Idiopathic dilated cardiomyopathy
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
111	Congenital myopathy
127	Frontotemporal lobar degeneration
137	Focal cortical dysplasia
157	Sturge-Weber syndrome
158	Tuberous sclerosis
192	Cockayne syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
227	Osler disease
277	Lymphangiomatosis
278	Huge lymphatic malformation with cervicofacial lesion
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
280	Huge arteriovenous malformation with cervicofacial or limb lesion
281	Klippel-Trenaunay-Weber syndrome
283	Acquired pure red cell aplasia
285	Fanconi anemia
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

Ticlopidine 💬

[1] Ticlopidine

[1] P2RY12 💬

[3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬

[1] 48 💬

Ticlopidine hydrochloride 💬

[1] Ticlopidine

[1] P2RY12 💬

[3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬

[1] 48 💬

Warfarin 💬

[1] Warfarin

[3] Warfarin; Warfarin Potassium; Warfarin Sodium

[2] NQO1,
VKORC1 💬

[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬

[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
66	IgA nephropathy
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
91	Budd-Chiari syndrome
96	Crohn disease
97	Ulcerative colitis
222	Primary nephrotic syndrome

Warfarin potassium 💬

[1] Warfarin

[3] Warfarin; Warfarin Potassium; Warfarin Sodium

[2] NQO1,
VKORC1 💬

[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬

[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
66	IgA nephropathy
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
91	Budd-Chiari syndrome
96	Crohn disease
97	Ulcerative colitis
222	Primary nephrotic syndrome

Warfarin sodium 💬

[1] Warfarin

[3] Warfarin; Warfarin Potassium; Warfarin Sodium

[2] NQO1,
VKORC1 💬

[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬

[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
66	IgA nephropathy
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
91	Budd-Chiari syndrome
96	Crohn disease
97	Ulcerative colitis
222	Primary nephrotic syndrome

Zanubrutinib 💬

[1] Zanubrutinib

[1] BTK 💬

[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬

[7] 13, 48, 61, 63, 222, 300, 331 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
48	Primary antiphospholipid syndrome
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
222	Primary nephrotic syndrome
300	IgG4-related disease
331	Idiopathic multicentric castleman disease