Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetylcysteine 💬[1] Acetylcysteine[1] Acetylcysteine--[10] 34, 51, 53, 85, 94, 97, 193, 233, 298, 299 💬
3 Acyclovir 💬[1] Acyclovir[3] Aciclovir; Acycloguanosine; Acyclovir--[5] 13, 28, 46, 53, 60 💬
4 Acyclovir sodium 💬[1] Acyclovir[3] Aciclovir; Acycloguanosine; Acyclovir--[5] 13, 28, 46, 53, 60 💬
5 Alginic acid 💬[1] Alginic acid[4] Algin; Alginate; Alginic acid; Sodium alginate--[4] 51, 53, 97, 299 💬
6 Anifrolumab 💬[1] Anifrolumab[1] Anifrolumab[2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[5] 46, 49, 50, 51, 53 💬
7 Baminercept 💬[1] Baminercept[1] Baminercept[1] LTB 💬 [3] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 13, 53, 97 💬
8 Baricitinib 💬[1] Baricitinib[1] Baricitinib[2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[19] 2, 13, 41, 46, 49, 50, 51, 53, 54, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
9 Belimumab 💬[1] Belimumab[1] Belimumab[1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 95, 222, 296 💬
10 Branebrutinib 💬[1] Branebrutinib[2] BMS-986195; Branebrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 46, 49, 53 💬
11 Bupivacaine 💬[1] Bupivacaine[2] Bupivacaine; Bupivacaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 46, 53, 70, 168, 226 💬
12 Bupivacaine hydrochloride 💬[1] Bupivacaine[2] Bupivacaine; Bupivacaine hydrochloride[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 46, 53, 70, 168, 226 💬
13 Calcium carbonate 💬[1] Calcium carbonate[1] Calcium carbonate--[7] 13, 19, 46, 75, 96, 235, 299 💬
14 Calcium carbonate 💬[1] Calcium carbonate[1] Calcium carbonate--[7] 13, 19, 46, 75, 96, 235, 299 💬
15 Cenegermin 💬[1] Cenegermin[1] Cenegermin[1] NGFR 💬 [9] Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Virion - Ebolavirus, Lyssavirus and Morbillivirus 💬[1] 53 💬
16 Cepharanthine 💬[1] Cepharanthine[2] Cepharanthin; Cepharanthine--[1] 53 💬
17 Cevimeline 💬[1] Cevimeline[1] Cevimeline[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[1] 53 💬
18 Cevimeline hydrochloride 💬[1] Cevimeline[1] Cevimeline[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[1] 53 💬
19 Cholecalciferol 💬[1] Cholecalciferol[4] Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[15] 6, 13, 19, 20, 34, 46, 49, 51, 53, 65, 96, 97, 228, 298, 299 💬
20 Citric acid monohydrate 💬[1] Citric acid[1] Citric acid--[1] 53 💬
21 Citric acid, anhydrous 💬[1] Citric acid[1] Citric acid--[1] 53 💬
22 Cyclosporine 💬[1] Cyclosporine[6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
23 Deucravacitinib 💬[1] Deucravacitinib[1] Deucravacitinib[1] TYK2 💬 [17] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis 💬[9] 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
24 Dexamethasone 💬[1] Dexamethasone[2] Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[23] 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
25 Dexamethasone phosphate 💬[1] Dexamethasone[2] Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[23] 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
26 Dexamethasone sodium phosphate 💬[1] Dexamethasone[2] Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[23] 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
27 Diquafosol tetrasodium 💬[1] Diquafosol[1] Diquafosol[1] P2RY2 💬 [4] Efferocytosis, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 53 💬
28 Dornase alfa 💬[1] Dornase alfa[2] Dornase alfa; Dornase alpha--[2] 53, 299 💬
29 Efalizumab 💬[1] Efalizumab[1] Efalizumab[1] ITGAL 💬 [12] Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
30 Efgartigimod alfa 💬[1] Efgartigimod alfa[1] Efgartigimod alfa--[6] 11, 14, 35, 53, 63, 162 💬
31 Estetrol 💬[1] Estetrol[1] Estetrol[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 53 💬
32 Estetrol 💬[1] Estetrol[1] Estetrol[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 53 💬
33 Etanercept 💬[1] Etanercept[1] Etanercept[2] LTA,
TNF 💬 		[66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[15] 15, 35, 38, 39, 46, 50, 53, 60, 85, 107, 228, 270, 271, 285, 298 💬
34 Filgotinib 💬[1] Filgotinib[2] Filgotinib; Filgotinib maleate[1] JAK1 💬 [27] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
35 Filgotinib maleate 💬[1] Filgotinib[2] Filgotinib; Filgotinib maleate[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
36 Glycyrrhiza 💬[1] Licorice[2] Licorice; Liquorice--[4] 46, 53, 83, 224 💬
37 Hyaluronate sodium 💬[1] Hyaluronic acid[3] Hyaluronan; Hyaluronic acid; Sodium hyaluronate--[6] 46, 53, 70, 97, 226, 299 💬
38 Hyaluronic acid 💬[1] Hyaluronic acid[3] Hyaluronan; Hyaluronic acid; Sodium hyaluronate--[6] 46, 53, 70, 97, 226, 299 💬
39 Hydrocortisone 💬[1] Hydrocortisone[3] Cortisol; Hydrocortisone; Hydrocortisonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[8] 41, 53, 75, 78, 81, 83, 97, 299 💬
40 Hydroxychloroquine 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; Hydroxychloroquine sulfate--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
41 Hydroxychloroquine sulfate 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; Hydroxychloroquine sulfate--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
42 Ianalumab 💬[1] Ianalumab[1] Ianalumab[1] TNFRSF13C 💬 [5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[8] 35, 46, 49, 51, 53, 61, 63, 95 💬
43 Iguratimod 💬[1] Iguratimod[1] Iguratimod[1] NFKB1 💬 [75] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[6] 46, 49, 51, 53, 271, 300 💬
44 Insulin lispro 💬[1] Insulin lispro[1] Insulin lispro[1] INSR 💬 [23] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 53 💬
45 Iscalimab 💬[1] Iscalimab[1] Iscalimab[1] TNFRSF5 💬 [17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[2] 49, 53 💬
46 Lanraplenib 💬[1] Lanraplenib[1] Lanraplenib--[2] 53, 222 💬
47 Leflunomide 💬[1] Leflunomide[2] Leflunomide; Leflunomidum[1] DHODH 💬 [1] Pyrimidine metabolism 💬[13] 11, 40, 46, 49, 53, 54, 66, 107, 162, 224, 270, 271, 300 💬
48 Leniolisib 💬[1] Leniolisib[2] Leniolisib; Leniolisib phosphate[3] PIK3CA_B_D,
PIK3CA_B_D,
PIK3CA_B_D 💬 		[103] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[2] 53, 65 💬
49 Leniolisib phosphate 💬[1] Leniolisib[2] Leniolisib; Leniolisib phosphate[1] PIK3CA_B_D 💬 [103] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[2] 53, 65 💬
50 Levocarnitine 💬[1] Levocarnitine[3] Carnitine; L-carnitine; Levocarnitine--[10] 3, 13, 46, 53, 58, 86, 96, 97, 240, 265 💬
51 Levocarnitine chloride 💬[1] Levocarnitine[3] Carnitine; L-carnitine; Levocarnitine--[10] 3, 13, 46, 53, 58, 86, 96, 97, 240, 265 💬
52 Levofloxacin 💬[1] Levofloxacin[2] Levofloxacin; Levofloxacin hemihydrate--[4] 46, 53, 84, 299 💬
53 Levofloxacin 💬[1] Levofloxacin[2] Levofloxacin; Levofloxacin hemihydrate--[4] 46, 53, 84, 299 💬
54 Methotrexate 💬[1] Methotrexate[5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
55 Methotrexate sodium 💬[1] Methotrexate[5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
56 Mirabegron 💬[1] Mirabegron[1] Mirabegron[1] ADRB3 💬 [9] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
57 Mizoribine 💬[1] Mizoribine[1] Mizoribine[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
58 Monomethyl fumarate 💬[1] Monomethyl fumarate[1] Monomethyl fumarate--[1] 13 💬
59 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
60 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
61 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
62 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
63 Nipocalimab 💬[1] Nipocalimab[1] Nipocalimab--[6] 11, 14, 46, 49, 53, 61 💬
64 Nivolumab 💬[1] Nivolumab[1] Nivolumab[1] PDCD1 💬 [3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
65 Olive oil 💬[1] Olive oil[1] Olive OIL--[3] 34, 49, 53 💬
66 Omalizumab 💬[1] Omalizumab[1] Omalizumab[1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
67 Oxybutynin 💬[1] Oxybutynin[0] [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬-
68 Oxybutynin chloride 💬[1] Oxybutynin[0] [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬-
69 Parsaclisib 💬[1] Parsaclisib[2] INCB050465; Parsaclisib[1] PIK3CA_B_D 💬 [103] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[3] 35, 53, 61 💬
70 Pilocarpine 💬[1] Pilocarpine[2] Pilocarpine; Pilocarpine hydrochloride[2] CHRM2,
CHRM3 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
71 Pilocarpine hydrochloride 💬[1] Pilocarpine[2] Pilocarpine; Pilocarpine hydrochloride[2] CHRM2,
CHRM3 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
72 Pilocarpine nitrate 💬[1] Pilocarpine[2] Pilocarpine; Pilocarpine hydrochloride[2] CHRM2,
CHRM3 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
73 Prasterone 💬[1] Prasterone[3] Dehydroepiandrosterone; Dhea; Prasterone[3] AR,
ESR1,
ESR2 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 49, 53, 83, 96 💬
74 Prednisone 💬[1] Prednisone[2] Prednisona; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
75 Ravagalimab 💬[1] Ravagalimab[1] Ravagalimab[1] TNFRSF5 💬 [17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[3] 46, 53, 97 💬
76 Rebamipide 💬[1] Rebamipide[1] Rebamipide--[4] 46, 53, 97, 271 💬
77 Remibrutinib 💬[1] Remibrutinib[1] Remibrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 11, 13, 53 💬
78 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
79 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[44] 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
80 Sodium alginate 💬[1] Alginic acid[4] Algin; Alginate; Alginic acid; Sodium alginate--[4] 51, 53, 97, 299 💬
81 Sodium chloride 💬[1] Sodium chloride[2] Natriumchlorid; Sodium chloride--[20] 2, 11, 13, 14, 34, 41, 46, 51, 53, 60, 67, 70, 96, 97, 193, 214, 215, 227, 288, 299 💬
82 Sulfuric acid 💬[1] Sulfate ion[1] Sulfate--[6] 2, 3, 11, 49, 222, 224 💬
83 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
84 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
85 Tetracycline 💬[1] Tetracycline[2] Tetracyclin; Tetracycline--[6] 13, 36, 46, 53, 66, 97 💬
86 Tetracycline hydrochloride 💬[1] Tetracycline[2] Tetracyclin; Tetracycline--[6] 13, 36, 46, 53, 66, 97 💬
87 Thalidomide 💬[1] Thalidomide[1] Thalidomide[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300 💬
88 Tibulizumab 💬[1] Tibulizumab[1] Tibulizumab[2] IL17A,
TNFSF13B 💬 		[8] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis, Th17 cell differentiation 💬[2] 51, 53 💬
89 Tirabrutinib 💬[1] Tirabrutinib[1] Tirabrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 46, 53 💬
90 Tirabrutinib hydrochloride 💬[1] Tirabrutinib[1] Tirabrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 46, 53 💬
91 Tocilizumab 💬[1] Tocilizumab[1] Tocilizumab[1] IL6R 💬 [11] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[24] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
92 Tofacitinib 💬[1] Tofacitinib[3] Tasocitinib; Tofacitinib; Tofacitinib citrate[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[19] 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 96, 97, 107, 110, 162, 271, 300 💬
93 Tofacitinib citrate 💬[1] Tofacitinib[3] Tasocitinib; Tofacitinib; Tofacitinib citrate[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[19] 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 96, 97, 107, 110, 162, 271, 300 💬
94 Triamcinolone 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
95 Triamcinolone acetonide 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
96 Triamcinolone diacetate 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
97 Triamcinolone hexacetonide 💬[1] Triamcinolone[3] Triamcinolone; Triamcinolone acetonide; Triamcinolone hexacetonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 46, 53, 56, 90, 96, 107, 226, 298 💬
98 Upadacitinib 💬[1] Upadacitinib[1] Upadacitinib[1] JAK1 💬 [27] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[10] 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
99 Upadacitinib hydrate 💬[1] Upadacitinib[1] Upadacitinib[1] JAK1 💬 [27] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[10] 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
100 Upadacitinib tartrate 💬[1] Upadacitinib[1] Upadacitinib[1] JAK1 💬 [27] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[10] 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
101 Ustekinumab 💬[1] Ustekinumab[1] Ustekinumab[3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[16] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
102 Varenicline 💬[1] Varenicline[2] Varenicline; Varenicline tartrate[2] CHRNA4,
CHRNB2 💬 		[5] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[2] 6, 18 💬
103 Varenicline tartrate 💬[1] Varenicline[2] Varenicline; Varenicline tartrate[2] CHRNA4,
CHRNB2 💬 		[5] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[2] 6, 18 💬
104 Vitamin A 💬[1] Vitamin A[1] Vitamin A[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90 💬
105 Vitamin A oil 💬[1] Vitamin A[1] Vitamin A--[3] 13, 53, 90 💬
106 Water 💬[1] Water[1] Water--[25] 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬
107 Wheat 💬[1] Wheat[0] ---
108 Xylitol 💬[1] Xylitol[1] Xylitol--[3] 53, 97, 299 💬
109 Yellow fever vaccine 💬[1] Yellow fever vaccine[1] Yellow fever vaccine--[8] 40, 44, 46, 50, 51, 52, 53, 107 💬