Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acyclovir 💬[1] Acyclovir[3] Aciclovir; Acycloguanosine; Acyclovir--[5] 13, 28, 46, 53, 60 💬
3 Acyclovir sodium 💬[1] Acyclovir[3] Aciclovir; Acycloguanosine; Acyclovir--[5] 13, 28, 46, 53, 60 💬
4 Alefacept 💬[1] Alefacept[1] Alefacept[1] CD58 💬 [2] Cell adhesion molecules, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285 💬
5 Alemtuzumab 💬[1] Alemtuzumab[1] Alemtuzumab--[18] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
6 Allopurinol 💬[1] Allopurinol[2] Allopurinol; Allopurinol sodium[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
7 Allopurinol sodium 💬[1] Allopurinol[2] Allopurinol; Allopurinol sodium[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
8 Amikacin 💬[1] Amikacin[2] Amikacin; Amikacin sulfate--[2] 60, 299 💬
9 Amikacin sulfate 💬[1] Amikacin[2] Amikacin; Amikacin sulfate--[2] 60, 299 💬
10 Anti-human thymocyte immunoglobulin, equine 💬[1] Antilymphocyte immunoglobulin (horse)[3] ANTI-thymocyte globulin; Hatg; Horse ANTI-thymocyte globulin--[3] 60, 285, 326 💬
11 Anti-human thymocyte immunoglobulin, rabbit 💬[1] Antithymocyte immunoglobulin (rabbit)[9] ANTI-thymocyte globulin; Antithymocyte immunoglobulin; Lapine T-lymphocyte immune globulin; Rabbit ANTI-human thymocyte immunoglobulin; Rabbit antithymocyte globulin; Rabbit ATG; Ratg; Thymoglobulin; Thymoglobuline[11] CD2,
CD3D,
CD3E,
CD3G,
CD4,
CD5,
CD7,
CD8A,
CD8B,
IL2RA,
ITGAL 💬 		[31] Antigen processing and presentation, Cell adhesion molecules, Chagas disease, Cytokine-cytokine receptor interaction, Endocytosis, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Leukocyte transendothelial migration, Malaria, Measles, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral life cycle - HIV-1, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus, Yersinia infection 💬[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
12 Avatrombopag 💬[1] Avatrombopag[2] Avatrombopag; Avatrombopag maleate[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
13 Avatrombopag maleate 💬[1] Avatrombopag[2] Avatrombopag; Avatrombopag maleate[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
14 Busulfan 💬[1] Busulfan[2] Busulfan; Busulfano--[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
15 Carboplatin 💬[1] Carboplatin[2] Carboplatin; Cbdca--[4] 28, 34, 60, 85 💬
16 Carmustine 💬[1] Carmustine[2] Carmustina; Carmustine--[5] 11, 13, 14, 28, 60 💬
17 Caspofungin 💬[1] Caspofungin[1] Caspofungin acetate--[1] 60 💬
18 Caspofungin acetate 💬[1] Caspofungin[1] Caspofungin acetate--[1] 60 💬
19 Cefepime 💬[1] Cefepime[0] ---
20 Cefepime hydrochloride 💬[1] Cefepime[0] ---
21 Cilastatin 💬[1] Cilastatin[1] Cilastatin--[1] 60 💬
22 Cilastatin sodium 💬[1] Cilastatin[1] Cilastatin--[1] 60 💬
23 Ciprofloxacin 💬[1] Ciprofloxacin[2] Ciprofloxacin; Ciprofloxacin hydrochloride--[6] 2, 46, 60, 96, 97, 299 💬
24 Ciprofloxacin hydrochloride 💬[1] Ciprofloxacin[2] Ciprofloxacin; Ciprofloxacin hydrochloride--[6] 2, 46, 60, 96, 97, 299 💬
25 Ciprofloxacin lactate 💬[1] Ciprofloxacin[2] Ciprofloxacin; Ciprofloxacin hydrochloride--[6] 2, 46, 60, 96, 97, 299 💬
26 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 96, 234 💬
27 Creatinine 💬[1] Creatinine[1] Creatinine--[6] 2, 46, 60, 66, 70, 222 💬
28 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
29 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
30 Cyclosporine 💬[1] Cyclosporine[6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
31 Cytarabine 💬[1] Cytarabine[2] Citarabina; Cytarabine--[7] 11, 13, 14, 25, 34, 49, 60 💬
32 Cytarabine hydrochloride 💬[1] Cytarabine[2] Citarabina; Cytarabine--[7] 11, 13, 14, 25, 34, 49, 60 💬
33 Daclizumab 💬[1] Daclizumab[1] Daclizumab[1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
34 Danazol 💬[1] Danazol[1] Danazol[3] AR,
ESR1,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
35 Dapsone 💬[1] Dapsone[1] Dapsone--[5] 35, 42, 60, 84, 162 💬
36 Daratumumab 💬[1] Daratumumab[1] Daratumumab[1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[7] 13, 28, 46, 48, 49, 60, 63 💬
37 Decitabine 💬[1] Decitabine[1] Decitabine[3] DNMT1,
DNMT3A,
DNMT3B 💬 		[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer 💬[2] 60, 63 💬
38 Dextrose 💬[1] Dextrose, unspecified form[2] Dextrose; Glucose--[12] 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
39 Edetic acid 💬[1] Edetic acid[1] Edta--[1] 60 💬
40 Eltrombopag choline 💬[1] Eltrombopag[2] Eltrombopag; Eltrombopag olamine[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
41 Eltrombopag olamine 💬[1] Eltrombopag[2] Eltrombopag; Eltrombopag olamine[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
42 Emapalumab 💬[1] Emapalumab[1] Emapalumab[1] IFNG 💬 [32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[4] 49, 54, 60, 107 💬
43 Etanercept 💬[1] Etanercept[1] Etanercept[2] LTA,
TNF 💬 		[66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[15] 15, 35, 38, 39, 46, 50, 53, 60, 85, 107, 228, 270, 271, 285, 298 💬
44 Etoposide 💬[1] Etoposide[1] Etoposide--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
45 Etoposide phosphate 💬[1] Etoposide[1] Etoposide--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
46 Ferrous fumarate 💬[1] Iron[1] Iron--[4] 60, 96, 97, 238 💬
47 Filgrastim 💬[1] Filgrastim[3] Filgrastim; G-CSF; Granulocyte colony stimulating factor[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[29] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
48 Fludarabine 💬[1] Fludarabine[2] Fludarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[25] 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
49 Fludarabine phosphate 💬[1] Fludarabine[2] Fludarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[25] 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
50 Foscarnet sodium 💬[1] Foscarnet[2] Foscarnet; Foscarnet sodium--[2] 28, 60 💬
51 Ganciclovir 💬[1] Ganciclovir[1] Ganciclovir--[3] 28, 60, 97 💬
52 Ganciclovir sodium 💬[1] Ganciclovir[1] Ganciclovir--[3] 28, 60, 97 💬
53 Glucose, liquid 💬[1] Dextrose, unspecified form[2] Dextrose; Glucose--[12] 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
54 Glycine 💬[1] Glycine[1] Glycine--[6] 35, 60, 226, 247, 299, 340 💬
55 Heparin calcium 💬[1] Heparin[2] Heparin; Heparin sodium[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[9] 47, 60, 65, 70, 84, 107, 226, 280, 299 💬
56 Heparin sodium 💬[1] Heparin[2] Heparin; Heparin sodium[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[9] 47, 60, 65, 70, 84, 107, 226, 280, 299 💬
57 Hyaluronidase 💬[1] Hyaluronidase[2] Hyaluronidase; Hyaluronoglucosaminidase--[4] 28, 51, 60, 65 💬
58 Hyaluronidase 💬[1] Hyaluronidase[2] Hyaluronidase; Hyaluronoglucosaminidase--[4] 28, 51, 60, 65 💬
59 Ibrutinib 💬[1] Ibrutinib[1] Ibrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 28, 60, 61 💬
60 Imipenem 💬[1] Imipenem[0] ---
61 Imipenem 💬[1] Imipenem[0] ---
62 Levamisole 💬[1] Levamisole[2] Levamisole; Levamisole hydrochloride--[3] 60, 61, 222 💬
63 Levamisole hydrochloride 💬[1] Levamisole[2] Levamisole; Levamisole hydrochloride--[3] 60, 61, 222 💬
64 Luspatercept 💬[1] Luspatercept[1] Luspatercept[1] ACVR2B 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[3] 60, 61, 282 💬
65 Lusutrombopag 💬[1] Lusutrombopag[1] Lusutrombopag[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
66 Macrogol 4000 💬[1] Polyethylene glycol[3] Macrogol; Macrogol 3350; Polyethylene glycol--[4] 50, 97, 195, 299 💬
67 Macrogol 6000 💬[1] Polyethylene glycol[3] Macrogol; Macrogol 3350; Polyethylene glycol--[4] 50, 97, 195, 299 💬
68 Magnesium pidolate 💬[1] Pidolic acid[0] ---
69 Mannitol 💬[1] Mannitol[2] Mannite; Mannitol--[6] 6, 13, 60, 96, 113, 299 💬
70 Medroxyprogesterone acetate 💬[1] Medroxyprogesterone acetate[0] [1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬-
71 Melphalan 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
72 Melphalan hydrochloride 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
73 Meropenem 💬[1] Meropenem[2] Meropenem; Meropenem trihydrate--[2] 60, 299 💬
74 Meropenem 💬[1] Meropenem[2] Meropenem; Meropenem trihydrate--[2] 60, 299 💬
75 Metformin 💬[1] Metformin[3] Metformin; Metformin hydrochloride; Metformina[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[27] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
76 Metformin hydrochloride 💬[1] Metformin[3] Metformin; Metformin hydrochloride; Metformina[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[27] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
77 Methadone 💬[1] Methadone[1] Methadone[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
OPRM1 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Estrogen signaling pathway, Glutamatergic synapse, Hormone signaling, Huntington disease, Long-term potentiation, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 60 💬
78 Methadone hydrochloride 💬[1] Methadone[1] Methadone[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
OPRM1 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Estrogen signaling pathway, Glutamatergic synapse, Hormone signaling, Huntington disease, Long-term potentiation, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 60 💬
79 Methotrexate 💬[1] Methotrexate[5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
80 Methotrexate sodium 💬[1] Methotrexate[5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
81 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
82 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
83 Monomethyl fumarate 💬[1] Monomethyl fumarate[1] Monomethyl fumarate--[1] 13 💬
84 Muromonab-CD3 💬[1] Muromonab[1] ANTI-CD3[3] CD3D,
CD3E,
CD3G 💬 		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 96 💬
85 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
86 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
87 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
88 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
89 Nandrolone 💬[1] Nandrolone[1] Nandrolone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 60 💬
90 Nandrolone decanoate 💬[1] Nandrolone decanoate[1] Nandrolone decanoate[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 60, 85 💬
91 Niacinamide 💬[1] Nicotinamide[2] Niacinamide; Nicotinamide--[7] 6, 13, 18, 49, 67, 107, 162 💬
92 Obatoclax mesylate 💬[1] Obatoclax[1] Obatoclax[1] BCL2 💬 [40] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬[1] 60 💬
93 Omidubicel 💬[1] Omidubicel[1] Omidubicel[1] CD34 💬 [2] Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 60 💬
94 Pegfilgrastim 💬[1] Pegfilgrastim[1] Pegfilgrastim[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 60 💬
95 Pentostatin 💬[1] Pentostatin[1] Pentostatin[1] add 💬 [2] Primary immunodeficiency, Purine metabolism 💬[1] 60 💬
96 Polyethylene glycol 3350 💬[1] Polyethylene glycol[3] Macrogol; Macrogol 3350; Polyethylene glycol--[4] 50, 97, 195, 299 💬
97 Posaconazole 💬[1] Posaconazole[1] Posaconazole--[3] 60, 65, 299 💬
98 Prednisolone 💬[1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[39] 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
99 Prednisone 💬[1] Prednisone[2] Prednisona; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
100 Rimiducid 💬[1] Rimiducid[1] Rimiducid[1] CASP9 💬 [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[7] 19, 49, 60, 65, 284, 285, 326 💬
101 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
102 Rivogenlecleucel 💬[1] Rivogenlecleucel[1] Rivogenlecleucel--[6] 19, 60, 65, 284, 285, 326 💬
103 Romiplostim 💬[1] Romiplostim[1] Romiplostim[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65 💬
104 Ruxolitinib 💬[1] Ruxolitinib[1] Ruxolitinib[2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[5] 13, 15, 60, 65, 228 💬
105 Ruxolitinib phosphate 💬[1] Ruxolitinib[1] Ruxolitinib[2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[5] 13, 15, 60, 65, 228 💬
106 Sargramostim 💬[1] Sargramostim[1] Sargramostim[1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
107 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[44] 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
108 Sodium chloride 💬[1] Sodium chloride[2] Natriumchlorid; Sodium chloride--[20] 2, 11, 13, 14, 34, 41, 46, 51, 53, 60, 67, 70, 96, 97, 193, 214, 215, 227, 288, 299 💬
109 Stanozolol 💬[1] Stanozolol[1] Stanozolol[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 60 💬
110 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
111 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
112 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[6] 1, 2, 3, 13, 76, 113 💬
113 Testosterone undecanoate 💬[1] Testosterone undecanoate[1] Testosterone undecanoate[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 13, 60 💬
114 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[11] 13, 28, 46, 51, 60, 65, 85, 96, 107, 284, 285 💬
115 Trimethoprim 💬[1] Trimethoprim[2] Trimethoprim; Trimethoprim sulfate--[4] 36, 60, 85, 299 💬
116 Trimethoprim hydrochloride 💬[1] Trimethoprim[2] Trimethoprim; Trimethoprim sulfate--[4] 36, 60, 85, 299 💬
117 Trimethoprim sulfate 💬[1] Trimethoprim[2] Trimethoprim; Trimethoprim sulfate--[4] 36, 60, 85, 299 💬
118 Valganciclovir 💬[1] Valganciclovir[1] Valganciclovir--[6] 28, 60, 85, 97, 299, 331 💬
119 Valganciclovir hydrochloride 💬[1] Valganciclovir[1] Valganciclovir--[6] 28, 60, 85, 97, 299, 331 💬
120 Voriconazole 💬[1] Voriconazole[1] Voriconazole--[2] 60, 299 💬