Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Alefacept 💬[1] Alefacept[1] Alefacept[1] CD58 💬 [2] Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285 💬
3 Alemtuzumab 💬[1] Alemtuzumab[1] Alemtuzumab--[21] 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
4 Allopurinol 💬[1] Allopurinol[2] Allopurinol; ALLOPURINOL SODIUM[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
5 Allopurinol sodium 💬[1] Allopurinol[2] Allopurinol; ALLOPURINOL SODIUM[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
6 Amikacin 💬[1] Amikacin[2] Amikacin; AMIKACIN SULFATE--[2] 60, 299 💬
7 Amikacin sulfate 💬[1] Amikacin[2] AMIKACIN; AMIKACIN SULFATE--[2] 60, 299 💬
8 Avatrombopag 💬[1] Avatrombopag[2] Avatrombopag; AVATROMBOPAG MALEATE[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
9 Avatrombopag maleate 💬[1] Avatrombopag[2] Avatrombopag; AVATROMBOPAG MALEATE[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
10 Busulfan 💬[1] Busulfan[2] Busulfan; BUSULFANO--[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
11 Carboplatin 💬[1] Carboplatin[1] Carboplatin--[4] 28, 34, 60, 85 💬
12 Carmustine 💬[1] Carmustine[2] CARMUSTINA; Carmustine--[5] 11, 13, 14, 28, 60 💬
13 Caspofungin 💬[1] Caspofungin[2] Caspofungin; CASPOFUNGIN ACETATE--[1] 60 💬
14 Caspofungin acetate 💬[1] Caspofungin[2] Caspofungin; CASPOFUNGIN ACETATE--[1] 60 💬
15 Cefepime 💬[1] Cefepime[1] Cefepime--[2] 60, 299 💬
16 Cefepime hydrochloride 💬[1] Cefepime[1] Cefepime--[2] 60, 299 💬
17 Cilastatin 💬[1] Cilastatin[1] CILASTATIN--[2] 60, 299 💬
18 Cilastatin sodium 💬[1] Cilastatin[1] Cilastatin--[2] 60, 299 💬
19 Ciprofloxacin 💬[1] Ciprofloxacin[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE--[6] 2, 46, 60, 96, 97, 299 💬
20 Ciprofloxacin hydrochloride 💬[1] Ciprofloxacin[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE--[6] 2, 46, 60, 96, 97, 299 💬
21 Ciprofloxacin lactate 💬[1] Ciprofloxacin[2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE--[6] 2, 46, 60, 96, 97, 299 💬
22 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
23 Creatinine 💬[1] Creatinine[1] Creatinine--[9] 2, 46, 49, 60, 66, 70, 96, 97, 222 💬
24 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
25 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
26 Cyclosporine 💬[1] Cyclosporine[7] CICLOSPORIN; Ciclosporina; Ciclosporine; CYCLOSPORIN; Cyclosporin A; Cyclosporine; Cyclosporine A[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
27 Cysteine hydrochloride 💬[1] Cysteine[2] Cysteine; Cysteine hydrochloride--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
28 Cytarabine 💬[1] Cytarabine[2] CITARABINA; Cytarabine--[8] 11, 13, 14, 25, 34, 49, 60, 65 💬
29 Cytarabine hydrochloride 💬[1] Cytarabine[2] CITARABINA; Cytarabine--[8] 11, 13, 14, 25, 34, 49, 60, 65 💬
30 Daclizumab 💬[1] Daclizumab[1] Daclizumab[1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[10] 13, 26, 56, 60, 63, 65, 97, 107, 283, 284 💬
31 Danazol 💬[1] Danazol[1] Danazol[3] AR,
ESR1,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
32 Dapsone 💬[1] Dapsone[1] Dapsone--[6] 35, 42, 60, 63, 84, 162 💬
33 Daratumumab 💬[1] Daratumumab[1] DARATUMUMAB[1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[13] 13, 16, 28, 39, 46, 48, 49, 60, 63, 222, 223, 288, 331 💬
34 Decitabine 💬[1] Decitabine[1] Decitabine[3] DNMT1,
DNMT3A,
DNMT3B 💬 		[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer 💬[2] 60, 63 💬
35 Deferasirox 💬[1] Deferasirox[1] Deferasirox--[5] 54, 60, 254, 284, 286 💬
36 Eltrombopag choline 💬[1] Eltrombopag[2] Eltrombopag; ELTROMBOPAG OLAMINE[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
37 Eltrombopag olamine 💬[1] Eltrombopag[2] ELTROMBOPAG; ELTROMBOPAG OLAMINE[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
38 Emapalumab 💬[1] Emapalumab[2] Emapalumab; Emapalumab-Izsg[1] IFNG 💬 [32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[6] 49, 50, 54, 60, 65, 107 💬
39 Enarodustat 💬[1] Enarodustat[1] Enarodustat[3] EGLN1,
EGLN2,
EGLN3 💬 		[3] HIF-1 signaling pathway, Pathways in cancer, Renal cell carcinoma 💬[1] 60 💬
40 Etanercept 💬[1] Etanercept[1] Etanercept[2] LTA,
TNF 💬 		[66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
41 Etoposide 💬[1] Etoposide[1] Etoposide--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
42 Etoposide phosphate 💬[1] Etoposide[1] Etoposide--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
43 Ferrous fumarate 💬[1] Iron[1] Iron--[7] 18, 60, 96, 97, 238, 254, 284 💬
44 Filgrastim 💬[1] Filgrastim[4] Filgrastim; G-CSF; Gcsf; Granulocyte Colony Stimulating Factor[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[30] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
45 Fludarabine 💬[1] Fludarabine[3] FLUDARABINA; Fludarabine; Fludarabine Phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
46 Fludarabine phosphate 💬[1] Fludarabine[3] FLUDARABINA; Fludarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
47 Foscarnet sodium 💬[1] Foscarnet[2] Foscarnet; Foscarnet sodium--[2] 28, 60 💬
48 Ganciclovir 💬[1] Ganciclovir[1] Ganciclovir--[3] 28, 60, 97 💬
49 Ganciclovir sodium 💬[1] Ganciclovir[1] Ganciclovir--[3] 28, 60, 97 💬
50 Glycine 💬[1] Glycine[1] Glycine--[7] 35, 60, 86, 226, 247, 299, 340 💬
51 Golidocitinib 💬[1] Golidocitinib[1] Golidocitinib[1] JAK1 💬 [27] Coronavirus disease, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 60 💬
52 Goserelin 💬[1] Goserelin[1] Goserelin[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[2] 1, 60 💬
53 Goserelin acetate 💬[1] Goserelin[1] Goserelin[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[2] 1, 60 💬
54 Heparin calcium 💬[1] Heparin[2] Heparin; Heparin Sodium[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
55 Heparin sodium 💬[1] Heparin[2] Heparin; HEPARIN SODIUM[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
56 Hyaluronidase 💬[1] Hyaluronidase[1] Hyaluronidase--[7] 13, 14, 28, 51, 60, 65, 331 💬
57 Hyaluronidase 💬[1] Hyaluronidase[1] Hyaluronidase--[7] 13, 14, 28, 51, 60, 65, 331 💬
58 Hyaluronidase 💬[1] Hyaluronidase[1] Hyaluronidase--[7] 13, 14, 28, 51, 60, 65, 331 💬
59 Ibrutinib 💬[1] Ibrutinib[1] Ibrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 28, 60, 61 💬
60 Imipenem 💬[1] Imipenem[1] Imipenem--[3] 60, 296, 299 💬
61 Imipenem 💬[1] Imipenem[1] Imipenem--[3] 60, 296, 299 💬
62 L-Cysteine 💬[1] Cysteine[2] Cysteine; Cysteine hydrochloride--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
63 Letermovir 💬[1] Letermovir[1] Letermovir--[2] 60, 85 💬
64 Levamisole 💬[1] Levamisole[2] Levamisole; Levamisole hydrochloride--[4] 60, 61, 62, 222 💬
65 Levamisole hydrochloride 💬[1] Levamisole[2] Levamisole; Levamisole hydrochloride--[4] 60, 61, 62, 222 💬
66 Luspatercept 💬[1] Luspatercept[1] Luspatercept[1] ACVR2B 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[4] 60, 61, 63, 282 💬
67 Lusutrombopag 💬[1] Lusutrombopag[1] Lusutrombopag[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
68 Mannitol 💬[1] Mannitol[3] D-Mannitol; Mannite; Mannitol--[8] 6, 13, 21, 28, 60, 96, 113, 299 💬
69 Melphalan 💬[1] Melphalan[2] Melphalan; Melphalan Hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
70 Melphalan hydrochloride 💬[1] Melphalan[2] Melphalan; Melphalan Hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
71 Meropenem 💬[1] Meropenem[2] MEROPENEM; MEROPENEM TRIHYDRATE--[3] 60, 296, 299 💬
72 Meropenem 💬[1] Meropenem[2] Meropenem; MEROPENEM TRIHYDRATE--[3] 60, 296, 299 💬
73 Mesna 💬[1] Coenzyme M[1] Mesna--[12] 11, 13, 16, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬
74 Metformin 💬[1] Metformin[4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
75 Metformin hydrochloride 💬[1] Metformin[4] Metformin; Metformin hydrochloride; METFORMINA; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
76 Methadone 💬[1] Methadone[1] Methadone[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
OPRM1 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Estrogen signaling pathway, Glutamatergic synapse, Hormone signaling, Huntington disease, Long-term potentiation, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 60 💬
77 Methadone hydrochloride 💬[1] Methadone[1] Methadone[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
OPRM1 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Estrogen signaling pathway, Glutamatergic synapse, Hormone signaling, Huntington disease, Long-term potentiation, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 60 💬
78 Methotrexate 💬[1] Methotrexate[5] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
79 Methotrexate sodium 💬[1] Methotrexate[5] Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
80 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
81 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
82 Monoethanolamine 💬[1] Ethanolamine[1] Ethanolamine--[3] 60, 63, 279 💬
83 Muromonab-CD3 💬[1] Muromonab[2] Muromonab; Muromonab-CD3[3] CD3D,
CD3E,
CD3G 💬 		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 60 💬
84 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate Mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
85 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate Mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
86 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolate sodium; MYCOPHENOLIC ACID[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[11] 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
87 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolate sodium; MYCOPHENOLIC ACID[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[11] 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
88 Nandrolone 💬[1] Nandrolone[1] Nandrolone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 60, 85 💬
89 Nandrolone decanoate 💬[1] Nandrolone decanoate[1] Nandrolone Decanoate[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 60, 85 💬
90 Niacinamide 💬[1] Nicotinamide[2] Niacinamide; Nicotinamide--[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
91 Obatoclax mesylate 💬[1] Obatoclax[1] Obatoclax[1] BCL2 💬 [40] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬[1] 60 💬
92 Omidubicel 💬[1] Omidubicel[1] Omidubicel[1] CD34 💬 [2] Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage 💬[1] 60 💬
93 Pegfilgrastim 💬[1] Pegfilgrastim[1] Pegfilgrastim[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 60 💬
94 Pentostatin 💬[1] Pentostatin[1] Pentostatin[1] ADA 💬 [2] Primary immunodeficiency, Purine metabolism 💬[1] 60 💬
95 Posaconazole 💬[1] Posaconazole[1] Posaconazole--[4] 60, 65, 96, 299 💬
96 Prednisolone 💬[1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
97 Prednisone 💬[1] Prednisone[2] Prednisona; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
98 Rimiducid 💬[1] Rimiducid[1] Rimiducid[1] CASP9 💬 [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[7] 19, 49, 60, 65, 284, 285, 326 💬
99 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
100 Rivogenlecleucel 💬[1] Rivogenlecleucel[1] Rivogenlecleucel--[6] 19, 60, 65, 284, 285, 326 💬
101 Romiplostim 💬[1] Romiplostim[1] ROMIPLOSTIM[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65 💬
102 Ruxolitinib 💬[1] Ruxolitinib[1] Ruxolitinib[2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[7] 13, 15, 50, 60, 65, 228, 331 💬
103 Ruxolitinib phosphate 💬[1] Ruxolitinib[1] Ruxolitinib[2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[7] 13, 15, 50, 60, 65, 228, 331 💬
104 Sargramostim 💬[1] Sargramostim[1] Sargramostim[1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
105 Sirolimus 💬[1] Sirolimus[2] Rapamycin; Sirolimus[1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
106 Sodium chloride 💬[1] Sodium chloride[3] NaCl; Sodium Chloride; Sodium chloride solution--[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
107 Stanozolol 💬[1] Stanozolol[1] Stanozolol[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 60 💬
108 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
109 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
110 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
111 Testosterone undecanoate 💬[1] Testosterone undecanoate[1] Testosterone undecanoate[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 13, 60 💬
112 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[14] 13, 19, 20, 28, 46, 51, 60, 65, 85, 96, 107, 164, 284, 285 💬
113 Trimethoprim 💬[1] Trimethoprim[2] Trimethoprim; TRIMETHOPRIM SULFATE--[7] 36, 44, 49, 60, 61, 85, 299 💬
114 Trimethoprim hydrochloride 💬[1] Trimethoprim[2] Trimethoprim; TRIMETHOPRIM SULFATE--[7] 36, 44, 49, 60, 61, 85, 299 💬
115 Trimethoprim sulfate 💬[1] Trimethoprim[2] Trimethoprim; TRIMETHOPRIM SULFATE--[7] 36, 44, 49, 60, 61, 85, 299 💬
116 Valganciclovir 💬[1] Valganciclovir[1] Valganciclovir--[6] 28, 60, 85, 97, 299, 331 💬
117 Valganciclovir hydrochloride 💬[1] Valganciclovir[1] Valganciclovir--[6] 28, 60, 85, 97, 299, 331 💬
118 Voriconazole 💬[1] Voriconazole[1] VORICONAZOLE--[2] 60, 299 💬