Drug Description in Trials / DrugBank / KEGG DRUG

  

Search results

No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Aripiprazole 💬[1] Aripiprazole[1] Aripiprazole[4] DRD2,
DRD3,
HTR1A,
HTR2A 💬 		[14] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[3] 6, 74, 206 💬
2 Bromocriptine 💬[1] Bromocriptine[1] Bromocriptine[2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 57, 74 💬
3 Bromocriptine mesylate 💬[1] Bromocriptine[1] Bromocriptine[2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 57, 74 💬
4 Cabergoline 💬[1] Cabergoline[2] CABERGOLINA; CABERGOLINE[2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 74, 75, 77 💬
5 Dexamethasone 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
6 Dexamethasone phosphate 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
7 Dexamethasone sodium phosphate 💬[1] Dexamethasone[4] Dexametasone; Dexamethason; Dexamethasone; Dexamethasone sodium phosphate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
8 Dopamine 💬[1] Dopamine[1] Dopamine[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 7, 17, 74, 77 💬
9 Dopamine hydrochloride 💬[1] Dopamine[1] Dopamine[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 7, 17, 74, 77 💬
10 Glycyrrhiza 💬[1] Licorice[1] Licorice--[4] 46, 53, 74, 224 💬
11 Lapatinib 💬[1] Lapatinib[1] Lapatinib[2] EGFR,
ERBB2 💬 		[50] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, Virion - Hepatitis viruses 💬[3] 34, 74, 75 💬
12 Lapatinib ditosylate 💬[1] Lapatinib[1] Lapatinib[2] EGFR,
ERBB2 💬 		[50] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, Virion - Hepatitis viruses 💬[3] 34, 74, 75 💬
13 Metformin 💬[1] Metformin[4] Metformin; METFORMIN HYDROCHLORIDE; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
14 Metformin hydrochloride 💬[1] Metformin[4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
15 Paliperidone 💬[1] Paliperidone[1] Paliperidone[2] DRD2,
HTR2A 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 74 💬
16 Paliperidone palmitate 💬[1] Paliperidone[1] Paliperidone[2] DRD2,
HTR2A 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 74 💬
17 Pasireotide 💬[1] Pasireotide[4] Pasireotida; PASIREOTIDE; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 67, 74, 75, 77 💬
18 Pasireotide diaspartate 💬[1] Pasireotide[4] Pasireotida; PASIREOTIDE; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 67, 74, 75, 77 💬
19 Pasireotide pamoate 💬[1] Pasireotide[4] Pasireotida; Pasireotide; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 67, 74, 75, 77 💬
20 Pramipexole 💬[1] Pramipexole[3] Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 20, 74 💬
21 Pramipexole dihydrochloride 💬[1] Pramipexole[3] Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 20, 74 💬
22 Quinagolide 💬[1] Quinagolide[2] Quinagolide; QUINAGOLIDE HYDROCHLORIDE[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 74 💬
23 Quinagolide hydrochloride 💬[1] Quinagolide[2] Quinagolide; QUINAGOLIDE HYDROCHLORIDE[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 74 💬
24 Risperidone 💬[1] Risperidone[1] Risperidone[2] DRD2,
HTR2A 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[6] 8, 74, 156, 179, 187, 206 💬
25 Ropinirole 💬[1] Ropinirole[2] Ropinirole; ROPINIROLE HYDROCHLORIDE[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 309 💬
26 Ropinirole hydrochloride 💬[1] Ropinirole[2] Ropinirole; ROPINIROLE HYDROCHLORIDE[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 309 💬