Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Water 💬[1] Water[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
2 Niacin 💬[1] Niacin[2] Niacin; Nicotinic acid--[3] 6, 78, 79 💬
3 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[8] 1, 2, 3, 13, 60, 76, 78, 113 💬
4 Hydrocortisone 💬[1] Hydrocortisone[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
5 Gelatin 💬[1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid--[7] 19, 28, 62, 78, 97, 269, 299 💬
6 Clonidine 💬[1] Clonidine[4] Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78 💬
7 Cosyntropin 💬[1] Tetracosactide[4] Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin[1] MC2R 💬 [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 78, 83, 113, 145, 222 💬
8 Fluoxetine 💬[1] Fluoxetine[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206 💬
9 Caffeine 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
10 Anastrozole 💬[1] Anastrozole[2] ANASTROZOLE; Arimidex[1] CYP19A1 💬 [3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193 💬
11 Caffeine hydrate 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
12 Albumin human 💬[1] Albumin human[5] Albumin; Human albumin; Human serum albumin; Optison; Serum albumin--[3] 2, 78, 96 💬
13 Arginine 💬[2] Arginine,
L-arginine		[6] Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene--[12] 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299 💬
14 Mecasermin 💬[1] Mecasermin[3] INCRELEX; Mecasermin; MECASERMINA[2] GHR,
IGF1R 💬 		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[6] 65, 78, 96, 168, 265, 299 💬
15 Polyethylene glycol 3350 💬[1] Polyethylene glycol[4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350--[7] 6, 78, 96, 97, 235, 276, 299 💬
16 Dextromethorphan 💬[1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
17 Exenatide 💬[1] Exenatide[3] Bydureon; Byetta; Exenatide[1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
18 Pegvisomant 💬[1] Pegvisomant[1] Pegvisomant[1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 265 💬
19 Tesamorelin 💬[1] Tesamorelin[2] GHRH; Tesamorelin[1] GHRHR 💬 [2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265 💬
20 Donkey glue 💬[1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid--[7] 19, 28, 62, 78, 97, 269, 299 💬
21 Acipimox 💬[1] Acipimox[1] Acipimox--[2] 78, 265 💬
22 Tiratricol 💬[1] Tiratricol[1] TIRATRICOL[2] THRA,
THRB 💬 		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[2] 78, 139 💬
23 Somatostatin 💬[1] Somatostatin[1] Somatostatin[5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 67, 78 💬
24 Amitriptyline 💬[1] Amitriptyline[3] Amitriptylin; Amitriptyline; Amitriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299 💬
25 Diclofenac 💬[1] Diclofenac[3] Diclofenac; Diclofenac sodium; Diclofenac SR[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271 💬
26 Donepezil 💬[1] Donepezil[3] ARICEPT; DONEPEZIL; Donepezil Hydrochloride[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
27 Levothyroxine 💬[1] Levothyroxine[2] Levothyroxine; Thyroxine[2] THRA,
THRB 💬 		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 19, 49, 78, 80 💬
28 Liothyronine 💬[1] Liothyronine[3] Liothyronine; Liothyronine sodium; Triiodothyronine[2] THRA,
THRB 💬 		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 13, 78, 210, 212 💬
29 Melatonin 💬[1] Melatonin[2] Circadin; Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
30 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
31 Strontium ranelate 💬[1] Strontium ranelate[1] Strontium ranelate--[1] 78 💬
32 Somatorelin 💬[1] Somatorelin[2] GHRH; Somatorelin[1] GHRHR 💬 [2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 13, 78 💬
33 Tramadol 💬[1] Tramadol[2] Tramadol; Ultracet[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271 💬
34 Macimorelin 💬[1] Macimorelin[2] Macimorelin; Macrilen[1] GHSR 💬 [3] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 78 💬
35 Somatrogon 💬[1] Somatrogon[2] Ngenla; Somatrogon--[1] 78 💬
36 Somavaratan 💬[1] Somavaratan[1] Somavaratan[1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78 💬
37 Somapacitan 💬[1] Somapacitan[2] Sogroya; Somapacitan[1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 195 💬
38 Lonapegsomatropin 💬[1] Lonapegsomatropin[1] LONAPEGSOMATROPIN[1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78 💬