Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetylcysteine 💬[1] Acetylcysteine[4] ACETYLCYSTEINE; N acetyl cysteine; N-acetyl cysteine; N-acetylcysteine--[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
2 Alanine 💬[1] Alanine[2] Alanine; L-alanine--[8] 6, 13, 70, 94, 97, 251, 298, 299 💬
3 Aldafermin 💬[1] Aldafermin[1] Aldafermin[1] FGF19 💬 [10] Breast cancer, Calcium signaling pathway, Gastric cancer, MAPK signaling pathway, Melanoma, PI3K-Akt signaling pathway, Pathways in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 94 💬
4 Amoxicillin 💬[1] Amoxicillin[2] Amoxicilina; Amoxicillin--[9] 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
5 Amoxicillin 💬[1] Amoxicillin[2] Amoxicilina; Amoxicillin--[9] 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
6 Amoxicillin sodium 💬[1] Amoxicillin[2] Amoxicilina; Amoxicillin--[9] 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
7 Azathioprine 💬[1] Azathioprine[2] Azathioprine; AZATIOPRINA--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
8 Azathioprine sodium 💬[1] Azathioprine[2] AZATHIOPRINE; AZATIOPRINA--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
9 Bexotegrast 💬[1] Bexotegrast[1] Bexotegrast[3] ITGA5,
ITGB1,
ITGB6 💬 		[33] Arrhythmogenic right ventricular cardiomyopathy, Axon guidance, Bacterial invasion of epithelial cells, Cell adhesion molecule (CAM) interaction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IgSF CAM signaling, Integrin signaling, Leishmaniasis, Leukocyte transendothelial migration, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Phagocytosis, Platelet activation, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Small cell lung cancer, Tight junction, Toxoplasmosis, Virion - Herpesvirus, Virion - Rotavirus, Yersinia infection 💬[1] 94 💬
10 Bezafibrate 💬[1] Bezafibrate[1] Bezafibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[8] 20, 93, 94, 160, 296, 316, 324, 344 💬
11 Budesonide 💬[1] Budesonide[1] BUDESONIDE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
12 Capecitabine 💬[1] Capecitabine[1] Capecitabine[1] TYMS 💬 [3] Folate transport and metabolism, One carbon pool by folate, Pyrimidine metabolism 💬[1] 94 💬
13 Cenicriviroc 💬[1] Cenicriviroc[1] Cenicriviroc[2] CCR2,
CCR5 💬 		[11] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[1] 94 💬
14 Cenicriviroc mesylate 💬[1] Cenicriviroc[1] Cenicriviroc[2] CCR2,
CCR5 💬 		[11] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[1] 94 💬
15 Cladribine 💬[1] Cladribine[2] CLADRIBINA; CLADRIBINE[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 11, 13, 94 💬
16 Elafibranor 💬[1] Elafibranor[1] ELAFIBRANOR[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94 💬
17 Erlotinib 💬[1] Erlotinib[1] Erlotinib[1] EGFR 💬 [49] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬[2] 94, 160 💬
18 Erlotinib hydrochloride 💬[1] Erlotinib[1] Erlotinib[1] EGFR 💬 [49] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬[2] 94, 160 💬
19 Fenofibrate 💬[1] Fenofibrate[1] Fenofibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
20 Hymecromone 💬[1] Hymecromone[1] Hymecromone--[2] 85, 94 💬
21 Meglumine 💬[1] Meglumine[1] Meglumine--[4] 28, 53, 85, 94 💬
22 Methionine 💬[1] Methionine[2] L-methionine; Methionine--[9] 34, 75, 84, 93, 94, 229, 298, 300, 337 💬
23 Metronidazole 💬[1] Metronidazole[2] Metronidazol; METRONIDAZOLE--[7] 46, 51, 63, 94, 96, 97, 291 💬
24 Metronidazole hydrochloride 💬[1] Metronidazole[2] Metronidazol; Metronidazole--[7] 46, 51, 63, 94, 96, 97, 291 💬
25 Minocycline 💬[1] Minocycline[2] Minocycline; MINOCYCLINE HYDROCHLORIDE--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
26 Minocycline hydrochloride 💬[1] Minocycline[2] Minocycline; MINOCYCLINE HYDROCHLORIDE--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
27 Mitomycin 💬[1] Mitomycin[2] Mitomycin; Mitomycin C--[3] 94, 162, 329 💬
28 Mizoribine 💬[1] Mizoribine[1] Mizoribine[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
29 Norucholic acid 💬[1] norUrsodeoxycholic acid[2] Norucholic acid; NorUrsodeoxycholic Acid[1] NR1H4 💬 [1] Bile secretion 💬[1] 94 💬
30 Potassium 💬[1] Potassium[1] Potassium--[17] 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
31 Proline 💬[1] Proline[1] Proline--[3] 66, 94, 97 💬
32 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
33 Rosuvastatin 💬[1] Rosuvastatin[2] Rosuvastatin; ROSUVASTATIN CALCIUM[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
34 Rosuvastatin calcium 💬[1] Rosuvastatin[2] Rosuvastatin; Rosuvastatin calcium[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
35 Seladelpar 💬[1] Seladelpar[1] SELADELPAR[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
36 Seladelpar lysine 💬[1] Seladelpar[1] SELADELPAR[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
37 Simvastatin 💬[1] Simvastatin[2] Simvastatin; Simvastatine[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
38 Siplizumab 💬[1] Siplizumab[1] Siplizumab[1] CD2 💬 [3] Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage, IgSF CAM signaling 💬[2] 94, 95 💬
39 Sulfasalazine 💬[1] Sulfasalazine[2] Sulfasalazine; Sulphasalazine--[7] 46, 49, 86, 94, 107, 270, 271 💬
40 Thalidomide 💬[1] Thalidomide[1] Thalidomide[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
41 Ursodiol 💬[1] Ursodeoxycholic acid[3] UDCA; Ursodeoxycholic Acid; Ursodiol[1] NR1H4 💬 [1] Bile secretion 💬[10] 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
42 Vancomycin 💬[1] Vancomycin[1] Vancomycin--[9] 6, 13, 46, 70, 94, 96, 97, 296, 299 💬
43 Vancomycin hydrochloride 💬[1] Vancomycin[1] Vancomycin--[9] 6, 13, 46, 70, 94, 96, 97, 296, 299 💬
44 Vedolizumab 💬[1] Vedolizumab[1] VEDOLIZUMAB[2] ITGA4,
ITGB7 💬 		[18] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecule (CAM) interaction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, IgSF CAM signaling, Integrin signaling, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[3] 94, 96, 97 💬
45 Vidofludimus 💬[1] Vidofludimus[2] Vidofludimus; Vidofludimus calcium[1] DHODH 💬 [1] Pyrimidine metabolism 💬[5] 13, 46, 94, 96, 97 💬
46 Vidofludimus calcium 💬[1] Vidofludimus[2] Vidofludimus; Vidofludimus calcium[1] DHODH 💬 [1] Pyrimidine metabolism 💬[5] 13, 46, 94, 96, 97 💬
47 Volixibat 💬[1] Volixibat[2] VOLIXIBAT; Volixibat potassium--[2] 93, 94 💬
48 Volixibat potassium 💬[1] Volixibat[2] Volixibat; Volixibat potassium--[2] 93, 94 💬