Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Azathioprine 💬[1] Azathioprine[2] AZATHIOPRINE; Azatioprina--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
3 Azathioprine sodium 💬[1] Azathioprine[2] Azathioprine; AZATIOPRINA--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
4 Belimumab 💬[1] Belimumab[1] BELIMUMAB[1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[17] 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
5 Budesonide 💬[1] Budesonide[1] Budesonide[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
6 Cannabidiol 💬[1] Cannabidiol[1] CANNABIDIOL[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
7 Chloroquine 💬[1] Chloroquine[1] Chloroquine--[3] 46, 49, 95 💬
8 Chloroquine hydrochloride 💬[1] Chloroquine[1] Chloroquine--[3] 46, 49, 95 💬
9 Chloroquine phosphate 💬[1] Chloroquine[1] Chloroquine--[3] 46, 49, 95 💬
10 Chloroquine sulfate 💬[1] Chloroquine[1] Chloroquine--[3] 46, 49, 95 💬
11 Cyclosporine 💬[1] Cyclosporine[7] CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
12 Denosumab 💬[1] Denosumab[1] Denosumab[1] TNFSF11 💬 [8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬
13 Efalizumab 💬[1] Efalizumab[1] EFALIZUMAB[1] ITGAL 💬 [14] Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, IgSF CAM signaling, Integrin signaling, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬
14 Epoetin alfa 💬[1] Erythropoietin[3] EPOETIN ALFA; Erythropoietin; RhEPO[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
15 Epoetin epsilon 💬[1] Erythropoietin[3] Epoetin alfa; Erythropoietin; RhEPO[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
16 Epoetin theta 💬[1] Erythropoietin[3] EPOETIN ALFA; Erythropoietin; RhEPO[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
17 Epoetin zeta 💬[1] Erythropoietin[3] Epoetin alfa; ERYTHROPOIETIN; RhEPO[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
18 Ianalumab 💬[1] Ianalumab[1] Ianalumab[1] TNFRSF13C 💬 [5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[8] 35, 46, 49, 51, 53, 61, 63, 95 💬
19 Inebilizumab 💬[1] Inebilizumab[1] INEBILIZUMAB[1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[8] 11, 13, 46, 49, 51, 53, 95, 300 💬
20 Infliximab 💬[1] Infliximab[2] Infliximab; Infliximab-Dyyb[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
21 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
22 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
23 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate Mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
24 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate Mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
25 Prednisolone 💬[1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
26 Prednisolone hemisuccinate 💬[1] Prednisolone hemisuccinate[1] PREDNISOLONE SODIUM SUCCINATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 95 💬
27 Prednisolone sodium succinate 💬[1] Prednisolone hemisuccinate[1] PREDNISOLONE SODIUM SUCCINATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 95 💬
28 Prednisone 💬[1] Prednisone[2] Prednisona; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
29 Risedronate sodium 💬[1] Risedronic acid[3] Risedronate; RISEDRONATE SODIUM; Risedronic acid[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 46, 50, 93, 95, 107, 113, 274 💬
30 Risedronate sodium monohydrate 💬[1] Risedronic acid[3] Risedronate; Risedronate sodium; Risedronic acid[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 46, 50, 93, 95, 107, 113, 274 💬
31 Risedronic acid 💬[1] Risedronic acid[3] Risedronate; RISEDRONATE SODIUM; Risedronic acid[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 46, 50, 93, 95, 107, 113, 274 💬
32 Siplizumab 💬[1] Siplizumab[1] Siplizumab[1] CD2 💬 [3] Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage, IgSF CAM signaling 💬[2] 94, 95 💬
33 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
34 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
35 Ursodiol 💬[1] Ursodeoxycholic acid[3] UDCA; URSODEOXYCHOLIC ACID; Ursodiol[1] NR1H4 💬 [1] Bile secretion 💬[10] 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
36 Zetomipzomib 💬[1] Zetomipzomib[1] Zetomipzomib[2] PSMB8,
PSMB9 💬 		[1] Proteasome 💬[1] 95 💬
37 Zetomipzomib maleate 💬[1] Zetomipzomib[1] Zetomipzomib[2] PSMB8,
PSMB9 💬 		[1] Proteasome 💬[1] 95 💬
38 Zoledronate disodium 💬[1] Zoledronic acid[2] Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
39 Zoledronate trisodium 💬[1] Zoledronic acid[2] Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
40 Zoledronic acid 💬[1] Zoledronic acid[2] Zoledronic Acid; ZOLEDRONIC ACID MONOHYDRATE[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
41 Zoledronic acid 💬[1] Zoledronic acid[2] Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
42 Zoledronic acid hemipentahydrate 💬[1] Zoledronic acid[2] Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬