Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Benoxinate hydrochloride 💬[1] Oxybuprocaine (4-Amino-3-butoxy-2-ethyl ester benzoic acid)[1] Oxybuprocaine[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 6 💬
2 Benzoic acid 💬
(Benzoic acid)		[1] Benzoic acid (Benzoic acid)[1] Benzoic acid--[1] 51 💬
3 Bexarotene 💬[1] Bexarotene (p-benzoic acid)[1] Bexarotene[3] RXRA,
RXRB,
RXRG 💬 		[18] Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Efferocytosis, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[2] 13, 75 💬
4 Bumetanide 💬[1] Bumetanide (3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid)[1] Bumetanide[1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[4] 6, 57, 115, 158 💬
5 Diflunisal 💬[1] Diflunisal (2-benzoic acid)[1] Diflunisal[1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 28 💬
6 Iptacopan 💬[1] Iptacopan (4- benzoic acid)[1] Iptacopan[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[8] 11, 61, 62, 63, 66, 109, 222, 223 💬
7 Iptacopan hydrochloride 💬[1] Iptacopan (4- benzoic acid)[1] Iptacopan[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[8] 11, 61, 62, 63, 66, 109, 222, 223 💬
8 Lumacaftor 💬[1] Lumacaftor (3-benzoic acid)[1] LUMACAFTOR[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
9 Oxybuprocaine 💬[1] Oxybuprocaine (4-Amino-3-butoxy-2-ethyl ester benzoic acid)[1] Oxybuprocaine[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 6 💬
10 Probenecid 💬[1] Probenecid (4-benzoic acid)[1] Probenecid--[1] 25 💬
11 Sodium benzoate 💬[1] Benzoic acid (Benzoic acid)[1] Benzoic acid--[1] 51 💬
12 Sulfasalazine 💬[1] Sulfasalazine (2-Hydroxy-5-benzoic acid)[2] SULFASALAZINE; Sulphasalazine--[7] 46, 49, 86, 94, 107, 270, 271 💬