Drug Description in Trials / DrugBank / KEGG DRUG

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No.

KEGG DRUG

DrugBank

Drug (Description in trials)

KEGG GENES

KEGG PATHWAY

Disease ID

1

Hydrochlorothiazide 💬

[1] Hydrochlorothiazide (Enalapril/hctz)

[2] Esidrix; HYDROCHLOROTHIAZIDE

[1] SLC12A3 💬

[1] 💬

[4] 13, 67, 225, 235 💬

2

Irbesartan 💬

[1] Irbesartan (Enalapril Maleate)

[2] Aprovel; IRBESARTAN

[1] AGTR1 💬

[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬

[4] 66, 167, 168, 222 💬

3

Enalapril 💬
(Enalapril (INN), Enalapril (TN))

[1] Enalapril (Enalapril Maleate Oral Solution)

[2] Enalapril; Enalapril Maleate

[1] ACE 💬

[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬

[6] 19, 46, 66, 113, 210, 222 💬