KEGG DRUG

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No.

KEGG DRUG

DrugBank

Drug (Description in trials)

KEGG GENES

KEGG PATHWAY

Disease ID

Acetaminophen 💬

[1] Acetaminophen (ACETAMINOPHEN DEXTROMETHORPHAN HYDROBROMIDE and PHENYLEPHRINE HYDROCHLORIDE)

[4] Acetaminophen; Paracetamol; Tylenol; Ultracet

[2] PTGS1,
PTGS2 💬

[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬

[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬

Disease ID	Name
3	Spinal muscular atrophy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
70	Spinal stenosis
86	Pulmonary arterial hypertension
222	Primary nephrotic syndrome
256	Muscle glycogenosis
271	Ankylosing spondylitis
337	Homocystinuria

Lidocaine 💬

[1] Lidocaine (SECONDARY NUMB Lidocaine Phenylephrine Gel)

[4] Aloe; Lidocaine; Lignocaine; Xylocaine

[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬

Name	Full Name
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9

[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬

[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
51	Scleroderma
70	Spinal stenosis
84	Sarcoidosis
86	Pulmonary arterial hypertension
107	Juvenile idiopathic arthritis
168	Ehlers-Danlos syndrome
226	Interstitial cystitis with Hunners ulcer
256	Muscle glycogenosis

Promethazine 💬

[1] Promethazine (Promethazine hydrochloride and phenylephrine hydrochloride)

[1] Promethazine

[1] HRH1 💬

[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬

[1] 96 💬

Dextromethorphan 💬

[1] Dextromethorphan (Acetaminophen Dextromethorphan HBr Doxylamine succinate Phenylephrine HCl)

[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta

[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬

Name	Full Name
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
SIGMAR1	sigma non-opioid intracellular receptor 1

[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬

[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
78	Hypopituitarism
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
156	Rett syndrome

Lidocaine hydrochloride monohydrate

Name	Other Names
Lidocaine hydrochloride monohydrate	Lidocaine hydrochloride monohydrate Lidocaine (TN) Zingo (TN) 1% LIDOCAINE HCI 2% LIDOCAINE HCI LIDENZAL 1% LIDENZAL 2% LIDOCAINE HCI LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE NA PRELIDOPINE PRE-OPERATIVE SYSTEM

💬

[1] Lidocaine (SECONDARY NUMB Lidocaine Phenylephrine Gel)

[4] Aloe; Lidocaine; Lignocaine; Xylocaine

[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬

Name	Full Name
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9

[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬

[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
51	Scleroderma
70	Spinal stenosis
84	Sarcoidosis
86	Pulmonary arterial hypertension
107	Juvenile idiopathic arthritis
168	Ehlers-Danlos syndrome
226	Interstitial cystitis with Hunners ulcer
256	Muscle glycogenosis

Phenylephrine 💬
(Phenylephrine (INN), Phenylephrine Minims (TN))

[1] Phenylephrine (Phenylephrine)

[1] Phenylephrine

[3] ADRA1A,
ADRA1B,
ADRA1D 💬

[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬

[1] 22 💬