Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen (Rx Act Pain Relief Rapid Release)[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Acetazolamide 💬[1] Acetazolamide (Acetazolamide Extended-release)[1] Acetazolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[6] 13, 90, 115, 155, 225, 230 💬
3 Alfuzosin 💬[1] Alfuzosin (Alfuzosin Hydrochloride extended release)[1] Alfuzosin[1] ADRA1A 💬 [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13 💬
4 Alprazolam 💬[1] Alprazolam (Alprazolam Extended-release)[1] Alprazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75 💬
5 Amoxicillin 💬[1] Amoxicillin (Amoxicillin Extended-Release)[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
6 Amoxicillin 💬[1] Amoxicillin (Amoxicillin Extended-Release)[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--[7] 6, 46, 63, 96, 97, 222, 299 💬
7 Ascorbic acid 💬[1] Ascorbic acid (Vitamin C 500mg Time Release)[4] Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C--[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
8 Aspirin 💬[1] Acetylsalicylic acid (Aspirin and Dipyridamole Extended Release)[2] Acetylsalicylic Acid; Aspirin[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[12] 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
9 beta Carotene 💬[1] Beta carotene (Icaps Time Release)[3] Beta carotene; Beta-Carotene; BETACAROTENE--[2] 13, 96 💬
10 Biotin 💬[1] Biotin (Timed Release Vita-vim Srt)[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7--[5] 2, 8, 10, 13, 20 💬
11 Bisacodyl 💬[1] Bisacodyl (Delayed Release Laxative Bisacodyl)[1] Bisacodyl--[1] 13 💬
12 Bupropion 💬[1] Bupropion (Contrave Extended-Release)[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171 💬
13 Calcium carbonate 💬[1] Calcium carbonate (Swiss One Timed Release Tab)[3] Calcio carbonato; Calcium; Calcium carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
14 Calcium carbonate 💬[1] Calcium carbonate (Swiss One Timed Release Tab)[3] Calcio carbonato; Calcium; Calcium carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
15 Chlorphenamine 💬[1] Chlorpheniramine (Rapid Release Multi-Symptom Allergy Relief)[1] Clorfenamina[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14 💬
16 Choline 💬[1] Choline (Swiss One Timed Release Tab)[1] Choline--[4] 93, 171, 193, 299 💬
17 Clarithromycin 💬[1] Clarithromycin (Clarithromycin extended release)[1] CLARITHROMYCIN--[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
18 Clavulanic acid 💬[1] Clavulanic acid (Amoxicillin and Clavulanate Potassium Extended Release)[4] AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID--[1] 299 💬
19 Clonidine 💬[1] Clonidine (Clonidine hydrochloride extended-release)[4] Clonidin; Clonidina; Clonidine; Clonidine hydrochloride[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78 💬
20 Cyanocobalamin 💬[1] Cyanocobalamin (Timed Release B Complex 100 Srt)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
21 Cyanocobalamin Co 57 💬[1] Cyanocobalamin (Timed Release B Complex 100 Srt)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
22 Cyanocobalamin Co 58 💬[1] Cyanocobalamin (Timed Release B Complex 100 Srt)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
23 Cyanocobalamin Co 60 💬[1] Cyanocobalamin (Timed Release B Complex 100 Srt)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
24 Cysteamine 💬[1] Cysteamine (PROCYSBI Delayed-release)[8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; Cystagon; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI--[4] 8, 19, 21, 299 💬
25 Darifenacin 💬[1] Darifenacin (Darifenacin Hydrobromide Extended-Release)[2] Darifenacin; Emselex[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13 💬
26 Dexlansoprazole 💬[1] Dexlansoprazole (Dexlansoprazole delayed release)[1] Dexlansoprazole[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 98 💬
27 Dextromethorphan 💬[1] Dextromethorphan (Mucus Relief DM Immediate Release)[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
28 Diclofenac 💬[1] Diclofenac (Diclofenac Sodium Delayed-release)[3] Diclofenac; Diclofenac Sodium; Diclofenac SR[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271 💬
29 Diltiazem 💬[1] Diltiazem (Diltiazem Hydrochloride Extended Release)[2] Diltiazem; Diltiazem Hydrochloride[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86 💬
30 Dimethyl fumarate 💬[1] Dimethyl fumarate (Sandoz Dimethyl Fumarate Delayed-release Capsules)[3] Dimethyl fumarate; Dimethylfumarat; TECFIDERA[1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 49, 51, 86, 296 💬
31 Diphenhydramine 💬[1] Diphenhydramine (Extra Strength Tylenol Pain and Head Cold Night Rapid Release)[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
32 Dipyridamole 💬[1] Dipyridamole (Aspirin and Extended-release Dipyridamole)[1] Dipyridamole[2] PDE4A,
PDE5A 💬 		[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 46, 49, 51, 66, 96, 224 💬
33 Donepezil 💬[1] Donepezil (Memantine and Donepezil Hydrochlorides Extended-release)[3] ARICEPT; Donepezil; Donepezil hydrochloride[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
34 Doxycycline 💬[1] Doxycycline (Doxycycline Hyclate Delayed Release)[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
35 Doxycycline 💬[1] Doxycycline (Doxycycline Hyclate Delayed Release)[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
36 Duloxetine 💬[1] Duloxetine (Duloxetine Delayed-release Delayed-release)[3] CYMBALTA; Duloxetine; Duloxetine hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
37 Ergocalciferol 💬[1] Ergocalciferol (Timed Release Vita-vim Srt)[3] Ergocalciferol; Vitamin D; Vitamin D2[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299 💬
38 Erythromycin 💬[1] Erythromycin (Eryc Delayed-release Capsules)[1] Erythromycin--[5] 6, 36, 164, 228, 291 💬
39 Folic acid 💬[1] Folic acid (Swiss One Timed Release Tab)[5] Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE--[6] 6, 41, 46, 49, 84, 296 💬
40 Guanfacine 💬[1] Guanfacine (Guanfacine Extended-Release)[1] Guanfacine[1] ADRA2A 💬 [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 193 💬
41 Hydromorphone 💬[1] Hydromorphone (Hydromorph Contin-controlled Release Cap - 6mg)[1] Hydromorphone[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70 💬
42 Ibuprofen 💬[1] Ibuprofen (IBUPROFEN Immediate Release)[2] Ibuprofen; IBUPROFEN 200MG[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299 💬
43 Indomethacin 💬[1] Indomethacin (Indomethacin extended-release)[2] INDOMETACIN; Indomethacin[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
44 Inositol 💬[1] Inositol (Swiss One Timed Release Tab)[1] Inositol--[2] 96, 97 💬
45 Iodine 💬[1] Iodine (Timed Release Vita-vim Srt)[2] Iodine; Iodo--[2] 28, 46 💬
46 Ketoprofen 💬[1] Ketoprofen (Oruvail Extended Release)[1] Ketoprofen[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46 💬
47 Lamotrigine 💬
(LAMOTRIGINE EXTENDED RELEASE)		[1] Lamotrigine (Lamotrigine Extended Release)[2] Lamictal; LAMOTRIGINE[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 13, 34, 38, 114, 144 💬
48 Lansoprazole 💬[1] Lansoprazole (Equate Lansoprazole Delayed Release)[1] Lansoprazole[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299 💬
49 Levetiracetam 💬
(LEVETIRACETAM EXTENDED RELEASE)		[1] Levetiracetam (LEVETIRACETAM Extended-release)[2] KEPPRA; Levetiracetam[1] SV2A 💬 [1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
50 Lidocaine 💬[1] Lidocaine (Lidovix Delayed Release)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
51 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine (Lidovix Delayed Release)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
52 Loratadine 💬[1] Loratadine (KIRKLAND SIGNATURE ALLERCLEAR D 24 HR Extended Release)[2] Loratadina; Loratadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98 💬
53 Magnesium gluconate 💬[1] Magnesium gluconate (Swiss One Timed Release Tab)[2] Magnesium; Magnesium gluconate--[2] 296, 297 💬
54 Melatonin 💬[1] Melatonin (Melatonin Rapid Release Gelcaps 10 mg)[2] Circadin; Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
55 Memantine 💬[1] Memantine (Memantine and Donepezil Hydrochlorides Extended-release)[3] EBIXA; Memantine; Memantine hydrochloride[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
56 Mesalamine 💬[1] Mesalazine (Pentasa Extended-release Tablets 250mg)[10] 5-AminoSalicylic Acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; MESALAZINE; Mesalazinum; MEZAVANT; Pentasa; Salofalk--[5] 46, 96, 97, 98, 164 💬
57 Metformin 💬[1] Metformin (Metformin Hydrochloride Extended Release)[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
58 Methylphenidate 💬[1] Methylphenidate (JORNAY PM Extended-Release)[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
59 Metoprolol 💬[1] Metoprolol (Metoprolol Succinate Extended-release)[2] Metoprolol; Metoprolol succinate[1] ADRB1 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
60 Minocycline 💬[1] Minocycline (Minolira Extended Release)[3] Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin--[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
61 Misoprostol 💬[1] Misoprostol (Diclofenac Sodium and Misoprostol Delayed-Release)[1] Misoprostol[3] PTGER2,
PTGER3,
PTGER4 💬 		[9] Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway 💬[3] 46, 70, 271 💬
62 Morphine 💬[1] Morphine (Morphine Sulfate Extended-release)[2] Morphine; MORPHINE SULFATE[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 36, 46, 70, 85, 86 💬
63 Naltrexone 💬[1] Naltrexone (Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release)[2] Naltrexone; Naltrexone Hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
64 Naproxen 💬[1] Naproxen (Naproxen delayed release)[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271 💬
65 Nevirapine 💬[1] Nevirapine (Nevirapine Extended Release)[1] Nevirapine--[1] 265 💬
66 Niacin 💬[1] Niacin (Time Released Niacin 500 mg)[2] Niacin; Nicotinic acid--[3] 6, 78, 79 💬
67 Niacinamide 💬[1] Nicotinamide (Timed Release Vita-vim Srt)[3] Multivitamin; Niacinamide; Nicotinamide--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
68 Nifedipine 💬[1] Nifedipine (Mylan-nifedipine Extended Release)[1] Nifedipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81 💬
69 Omeprazole 💬[1] Omeprazole (Omeprazole Delayed-Release)[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
70 Oxybutynin 💬[1] Oxybutynin (Oxybutynin Chloride Extended Release)[1] Oxybutynin[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
71 Oxycodone 💬[1] Oxycodone (Oxycodone Hydrochloride Immediate-release)[2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
72 Oxymorphone 💬[1] Oxymorphone (Oxymorphone Hydrochloride Extended-Release)[1] Opana[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70 💬
73 Pantoprazole 💬[1] Pantoprazole (Pantoprazole sodium delayed-release)[1] Pantoprazole[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65 💬
74 Paroxetine 💬[1] Paroxetine (PAROXETINE HYDROCHLORIDE Controlled-Release)[1] Paroxetine[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
75 Phenylephrine 💬[1] Phenylephrine (WellBid-D Sustained-Release)[1] Phenylephrine[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22 💬
76 Potassium 💬[1] Potassium (Complete Multivitamins and Minerals Tablets Timed Release)[1] Potassium--[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
77 Pramipexole 💬[1] Pramipexole (Pramipexole Dihydrochloride Extended-Release)[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[3] DRD2,
DRD3,
DRD4 💬 		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20 💬
78 Pregabalin 💬
(PREGABALIN EXTENDED RELEASE)		[1] Pregabalin (Pregabalin Extended Release)[2] Lyrica; Pregabalin[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬 		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298 💬
79 Pseudoephedrine 💬[1] Pseudoephedrine (KIRKLAND SIGNATURE ALLERCLEAR D 24 HR Extended Release)[1] Pseudoephedrine[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
80 Pyridoxine 💬[1] Pyridoxine (Time Release B 100 Compound - Tablet)[2] PYRIDOXINE; Vitamin B6--[5] 6, 93, 145, 206, 320 💬
81 Quetiapine 💬[1] Quetiapine (Quetiapine Fumarate Extended Release)[2] Quetiapine; Seroquel[2] DRD2,
HTR2A 💬 		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
82 Rabeprazole 💬[1] Rabeprazole (Rabeprazole Sodium Delayed-release)[1] Rabeprazole[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51 💬
83 Ranitidine 💬[1] Ranitidine (Ranitidine Immediate release)[1] Ranitidine[1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65 💬
84 Riboflavin 💬[1] Riboflavin (Time Release B 100 Compound - Tablet)[2] Riboflavin; Vitamin B2--[7] 38, 46, 96, 97, 162, 168, 265 💬
85 Salicylic acid 💬[1] Salicylic acid (Smart Release Mandelic 8 PERCENT)[2] 2-Hydroxybenzoic acid; Salicylic acid--[1] 97 💬
86 Sodium fluoride 💬[1] Sodium fluoride (Flor-Opal Sustained-Release Fluoride)[1] Sodium fluoride--[1] 51 💬
87 Somatostatin 💬[1] Somatostatin (Synthetic growth hormone release-inhibiting hormone)[1] Somatostatin[5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 67, 78 💬
88 Sulfasalazine 💬[1] Sulfasalazine (Sulfasalazine Delayed-Release)[3] Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine--[6] 46, 86, 94, 107, 270, 271 💬
89 Theophylline 💬[1] Theophylline (Theophylline Extended Release)[1] Theophylline[18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299 💬
90 Theophylline 💬[1] Theophylline (Theophylline Extended Release)[1] Theophylline[18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299 💬
91 Thiamine 💬[1] Thiamine (Time Release B 100 Compound - Tablet)[2] THIAMINE; Vitamin B1--[4] 8, 93, 145, 265 💬
92 Tolterodine 💬[1] Tolterodine (Tolterodine Tartrate Extended Release)[1] Tolterodine[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53 💬
93 Tramadol 💬[1] Tramadol (Tramadol Hydrochloride Extended Release)[2] Tramadol; Ultracet[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271 💬
94 Valproic acid 💬[1] Valproic acid (Divalproex Sodium Extended-Release)[3] Valproate; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬
95 Venlafaxine 💬[1] Venlafaxine (Effexor XR Extended-Release)[2] Venlafaxine; Venlafaxine Hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46 💬
96 Vitamin A 💬[1] Vitamin A (Timed Release Vita-vim Srt)[1] Vitamin A[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90 💬
97 Vitamin E 💬[1] Vitamin E (Swiss One Timed Release Tab)[2] Alpha-tocopherol; Vitamin E--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
98 Zinc gluconate 💬[1] Zinc gluconate (Swiss One Timed Release Tab)[1] ZINC GLUCONATE--[1] 171 💬
99 Zolpidem 💬[1] Zolpidem (Zolpidem Tartrate Extended-Release)[2] Zolpidem; Zolpidem Tartrate[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬