Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||
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| 1 | African trypanosomiasis 💬 10 genes, 24 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬African trypanosomiasis
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Canakinumab Canakinumab 💬African trypanosomiasis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬1. African trypanosomiasis
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| 2 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 58 drugs (DrugBank) and 100 diseases |
IL1B [1] IL1B 💬AGE-RAGE signaling pathway in diabetic complications
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Canakinumab Canakinumab 💬AGE-RAGE signaling pathway in diabetic complications
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬2. AGE-RAGE signaling pathway in diabetic complications
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| 3 | Alcoholic liver disease 💬 43 genes, 56 drugs (DrugBank) and 98 diseases |
IL1B [1] IL1B 💬Alcoholic liver disease
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Canakinumab Canakinumab 💬Alcoholic liver disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬3. Alcoholic liver disease
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| 4 | Alzheimer disease 💬 59 genes, 136 drugs (DrugBank) and 139 diseases |
IL1B [1] IL1B 💬Alzheimer disease
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Canakinumab Canakinumab 💬Alzheimer disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬4. Alzheimer disease
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| 5 | Amoebiasis 💬 20 genes, 32 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬Amoebiasis
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Canakinumab Canakinumab 💬Amoebiasis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬5. Amoebiasis
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| 6 | C-type lectin receptor signaling pathway 💬 28 genes, 71 drugs (DrugBank) and 108 diseases |
IL1B [1] IL1B 💬C-type lectin receptor signaling pathway
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Canakinumab Canakinumab 💬C-type lectin receptor signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬6. C-type lectin receptor signaling pathway
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| 7 | Chagas disease 💬 32 genes, 59 drugs (DrugBank) and 88 diseases |
IL1B [1] IL1B 💬Chagas disease
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Canakinumab Canakinumab 💬Chagas disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬7. Chagas disease
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| 8 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
IL1B [1] IL1B 💬Coronavirus disease
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Canakinumab Canakinumab 💬Coronavirus disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬8. Coronavirus disease
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| 9 | Cytokine-cytokine receptor interaction 💬 90 genes, 141 drugs (DrugBank) and 104 diseases |
IL1B [1] IL1B 💬Cytokine-cytokine receptor interaction
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Canakinumab Canakinumab 💬Cytokine-cytokine receptor interaction
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬9. Cytokine-cytokine receptor interaction
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| 10 | Cytosolic DNA-sensing pathway 💬 21 genes, 17 drugs (DrugBank) and 34 diseases |
IL1B [1] IL1B 💬Cytosolic DNA-sensing pathway
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Canakinumab Canakinumab 💬Cytosolic DNA-sensing pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬10. Cytosolic DNA-sensing pathway
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| 11 | Fluid shear stress and atherosclerosis 💬 33 genes, 60 drugs (DrugBank) and 100 diseases |
IL1B [1] IL1B 💬Fluid shear stress and atherosclerosis
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Canakinumab Canakinumab 💬Fluid shear stress and atherosclerosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬11. Fluid shear stress and atherosclerosis
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| 12 | Graft-versus-host disease 💬 28 genes, 26 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬Graft-versus-host disease
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Canakinumab Canakinumab 💬Graft-versus-host disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬12. Graft-versus-host disease
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| 13 | Hematopoietic cell lineage 💬 47 genes, 97 drugs (DrugBank) and 101 diseases |
IL1B [1] IL1B 💬Hematopoietic cell lineage
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Canakinumab Canakinumab 💬Hematopoietic cell lineage
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬13. Hematopoietic cell lineage
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| 14 | Herpes simplex virus 1 infection 💬 71 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B [1] IL1B 💬Herpes simplex virus 1 infection
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Canakinumab Canakinumab 💬Herpes simplex virus 1 infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬14. Herpes simplex virus 1 infection
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| 15 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
IL1B [1] IL1B 💬Human cytomegalovirus infection
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Canakinumab Canakinumab 💬Human cytomegalovirus infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬15. Human cytomegalovirus infection
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| 16 | IL-17 signaling pathway 💬 20 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬IL-17 signaling pathway
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Canakinumab Canakinumab 💬IL-17 signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬16. IL-17 signaling pathway
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| 17 | Inflammatory bowel disease 💬 38 genes, 49 drugs (DrugBank) and 75 diseases |
IL1B [1] IL1B 💬Inflammatory bowel disease
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Canakinumab Canakinumab 💬Inflammatory bowel disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬17. Inflammatory bowel disease
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| 18 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
IL1B [1] IL1B 💬Inflammatory mediator regulation of TRP channels
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Canakinumab Canakinumab 💬Inflammatory mediator regulation of TRP channels
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬18. Inflammatory mediator regulation of TRP channels
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| 19 | Influenza A 💬 67 genes, 84 drugs (DrugBank) and 101 diseases |
IL1B [1] IL1B 💬Influenza A
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Canakinumab Canakinumab 💬Influenza A
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬19. Influenza A
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| 20 | Legionellosis 💬 10 genes, 24 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬Legionellosis
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Canakinumab Canakinumab 💬Legionellosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬20. Legionellosis
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| 21 | Leishmaniasis 💬 40 genes, 76 drugs (DrugBank) and 105 diseases |
IL1B [1] IL1B 💬Leishmaniasis
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Canakinumab Canakinumab 💬Leishmaniasis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬21. Leishmaniasis
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| 22 | Lipid and atherosclerosis 💬 52 genes, 73 drugs (DrugBank) and 107 diseases |
IL1B [1] IL1B 💬Lipid and atherosclerosis
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Canakinumab Canakinumab 💬Lipid and atherosclerosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬22. Lipid and atherosclerosis
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| 23 | Malaria 💬 17 genes, 31 drugs (DrugBank) and 69 diseases |
IL1B [1] IL1B 💬Malaria
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Canakinumab Canakinumab 💬Malaria
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬23. Malaria
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| 24 | MAPK signaling pathway 💬 70 genes, 101 drugs (DrugBank) and 117 diseases |
IL1B [1] IL1B 💬MAPK signaling pathway
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Canakinumab Canakinumab 💬MAPK signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬24. MAPK signaling pathway
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| 25 | Measles 💬 42 genes, 72 drugs (DrugBank) and 70 diseases |
IL1B [1] IL1B 💬Measles
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Canakinumab Canakinumab 💬Measles
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬25. Measles
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| 26 | Necroptosis 💬 34 genes, 60 drugs (DrugBank) and 82 diseases |
IL1B [1] IL1B 💬Necroptosis
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Canakinumab Canakinumab 💬Necroptosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬26. Necroptosis
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| 27 | NF-kappa B signaling pathway 💬 23 genes, 81 drugs (DrugBank) and 97 diseases |
IL1B [1] IL1B 💬NF-kappa B signaling pathway
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Canakinumab Canakinumab 💬NF-kappa B signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬27. NF-kappa B signaling pathway
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| 28 | NOD-like receptor signaling pathway 💬 33 genes, 57 drugs (DrugBank) and 79 diseases |
IL1B [1] IL1B 💬NOD-like receptor signaling pathway
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Canakinumab Canakinumab 💬NOD-like receptor signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬28. NOD-like receptor signaling pathway
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| 29 | Non-alcoholic fatty liver disease 💬 24 genes, 54 drugs (DrugBank) and 100 diseases |
IL1B [1] IL1B 💬Non-alcoholic fatty liver disease
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Canakinumab Canakinumab 💬Non-alcoholic fatty liver disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬29. Non-alcoholic fatty liver disease
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| 30 | Osteoclast differentiation 💬 40 genes, 93 drugs (DrugBank) and 109 diseases |
IL1B [1] IL1B 💬Osteoclast differentiation
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Canakinumab Canakinumab 💬Osteoclast differentiation
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬30. Osteoclast differentiation
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| 31 | Pathogenic Escherichia coli infection 💬 31 genes, 46 drugs (DrugBank) and 84 diseases |
IL1B [1] IL1B 💬Pathogenic Escherichia coli infection
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Canakinumab Canakinumab 💬Pathogenic Escherichia coli infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬31. Pathogenic Escherichia coli infection
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| 32 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
IL1B [1] IL1B 💬Pathways of neurodegeneration - multiple diseases
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Canakinumab Canakinumab 💬Pathways of neurodegeneration - multiple diseases
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬32. Pathways of neurodegeneration - multiple diseases
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| 33 | Pertussis 💬 23 genes, 48 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬Pertussis
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Canakinumab Canakinumab 💬Pertussis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬33. Pertussis
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| 34 | Prion disease 💬 41 genes, 77 drugs (DrugBank) and 121 diseases |
IL1B [1] IL1B 💬Prion disease
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Canakinumab Canakinumab 💬Prion disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬34. Prion disease
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| 35 | Rheumatoid arthritis 💬 39 genes, 59 drugs (DrugBank) and 85 diseases |
IL1B [1] IL1B 💬Rheumatoid arthritis
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Canakinumab Canakinumab 💬Rheumatoid arthritis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬35. Rheumatoid arthritis
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| 36 | Salmonella infection 💬 32 genes, 48 drugs (DrugBank) and 78 diseases |
IL1B [1] IL1B 💬Salmonella infection
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Canakinumab Canakinumab 💬Salmonella infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬36. Salmonella infection
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| 37 | Shigellosis 💬 31 genes, 54 drugs (DrugBank) and 97 diseases |
IL1B [1] IL1B 💬Shigellosis
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Canakinumab Canakinumab 💬Shigellosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬37. Shigellosis
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| 38 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
IL1B [1] IL1B 💬Th17 cell differentiation
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Canakinumab Canakinumab 💬Th17 cell differentiation
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬38. Th17 cell differentiation
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| 39 | TNF signaling pathway 💬 25 genes, 64 drugs (DrugBank) and 95 diseases |
IL1B [1] IL1B 💬TNF signaling pathway
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Canakinumab Canakinumab 💬TNF signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬39. TNF signaling pathway
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| 40 | Toll-like receptor signaling pathway 💬 41 genes, 68 drugs (DrugBank) and 84 diseases |
IL1B [1] IL1B 💬Toll-like receptor signaling pathway
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Canakinumab Canakinumab 💬Toll-like receptor signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬40. Toll-like receptor signaling pathway
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| 41 | Tuberculosis 💬 67 genes, 80 drugs (DrugBank) and 104 diseases |
IL1B [1] IL1B 💬Tuberculosis
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Canakinumab Canakinumab 💬Tuberculosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬41. Tuberculosis
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| 42 | Type I diabetes mellitus 💬 32 genes, 25 drugs (DrugBank) and 72 diseases |
IL1B [1] IL1B 💬Type I diabetes mellitus
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Canakinumab Canakinumab 💬Type I diabetes mellitus
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬42. Type I diabetes mellitus
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| 43 | Yersinia infection 💬 25 genes, 43 drugs (DrugBank) and 78 diseases |
IL1B [1] IL1B 💬Yersinia infection
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Canakinumab Canakinumab 💬Yersinia infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬43. Yersinia infection
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African trypanosomiasis
10 genes, 24 drugs (DrugBank) and 66 diseases
AGE-RAGE signaling pathway in diabetic complications
28 genes, 58 drugs (DrugBank) and 100 diseases
Alcoholic liver disease
43 genes, 56 drugs (DrugBank) and 98 diseases
Alzheimer disease
59 genes, 136 drugs (DrugBank) and 139 diseases
Amoebiasis
20 genes, 32 drugs (DrugBank) and 77 diseases
C-type lectin receptor signaling pathway
28 genes, 71 drugs (DrugBank) and 108 diseases
Chagas disease
32 genes, 59 drugs (DrugBank) and 88 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Cytokine-cytokine receptor interaction
90 genes, 141 drugs (DrugBank) and 104 diseases
Cytosolic DNA-sensing pathway
21 genes, 17 drugs (DrugBank) and 34 diseases
Fluid shear stress and atherosclerosis
33 genes, 60 drugs (DrugBank) and 100 diseases
Graft-versus-host disease
28 genes, 26 drugs (DrugBank) and 68 diseases
Hematopoietic cell lineage
47 genes, 97 drugs (DrugBank) and 101 diseases
Herpes simplex virus 1 infection
71 genes, 85 drugs (DrugBank) and 110 diseases
Human cytomegalovirus infection
65 genes, 121 drugs (DrugBank) and 136 diseases
IL-17 signaling pathway
20 genes, 65 drugs (DrugBank) and 91 diseases
Inflammatory bowel disease
38 genes, 49 drugs (DrugBank) and 75 diseases
Inflammatory mediator regulation of TRP channels
26 genes, 55 drugs (DrugBank) and 70 diseases
Influenza A
67 genes, 84 drugs (DrugBank) and 101 diseases
Legionellosis
10 genes, 24 drugs (DrugBank) and 68 diseases
Leishmaniasis
40 genes, 76 drugs (DrugBank) and 105 diseases
Lipid and atherosclerosis
52 genes, 73 drugs (DrugBank) and 107 diseases
Malaria
17 genes, 31 drugs (DrugBank) and 69 diseases
MAPK signaling pathway
70 genes, 101 drugs (DrugBank) and 117 diseases
Measles
42 genes, 72 drugs (DrugBank) and 70 diseases
Necroptosis
34 genes, 60 drugs (DrugBank) and 82 diseases
NF-kappa B signaling pathway
23 genes, 81 drugs (DrugBank) and 97 diseases
NOD-like receptor signaling pathway
33 genes, 57 drugs (DrugBank) and 79 diseases
Non-alcoholic fatty liver disease
24 genes, 54 drugs (DrugBank) and 100 diseases
Osteoclast differentiation
40 genes, 93 drugs (DrugBank) and 109 diseases
Pathogenic Escherichia coli infection
31 genes, 46 drugs (DrugBank) and 84 diseases
Pathways of neurodegeneration - multiple diseases
64 genes, 143 drugs (DrugBank) and 141 diseases
Pertussis
23 genes, 48 drugs (DrugBank) and 77 diseases
Prion disease
41 genes, 77 drugs (DrugBank) and 121 diseases
Rheumatoid arthritis
39 genes, 59 drugs (DrugBank) and 85 diseases
Salmonella infection
32 genes, 48 drugs (DrugBank) and 78 diseases
Shigellosis
31 genes, 54 drugs (DrugBank) and 97 diseases
Th17 cell differentiation
57 genes, 88 drugs (DrugBank) and 111 diseases
TNF signaling pathway
25 genes, 64 drugs (DrugBank) and 95 diseases
Toll-like receptor signaling pathway
41 genes, 68 drugs (DrugBank) and 84 diseases
Tuberculosis
67 genes, 80 drugs (DrugBank) and 104 diseases
Type I diabetes mellitus
32 genes, 25 drugs (DrugBank) and 72 diseases
Yersinia infection
25 genes, 43 drugs (DrugBank) and 78 diseases
