Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
2 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
3 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
CSF2 [1] CSF2 💬
|
Otilimab Otilimab 💬
| Otilimab | 046 [1] 46 💬
|
4 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
5 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
FYN [2] FYN, LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
6 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Rontalizumab Rontalizumab 💬
| Rontalizumab | 049 [1] 49 💬
|
7 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Sifalimumab Sifalimumab 💬
| Sifalimumab | 049 [1] 49 💬
|
8 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Anifrolumab Anifrolumab 💬
| Anifrolumab | 046 [3] 46, 49, 53 💬
|
9 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
10 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
11 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
12 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon beta-1a Interferon beta-1a 💬
| Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬
|
13 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon beta-1b Interferon beta-1b 💬
| Interferon beta-1b | 013 [1] 13 💬
|
14 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Peginterferon beta-1a Peginterferon beta-1a 💬
| Peginterferon beta-1a | 013 [1] 13 💬
|
15 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNG [1] IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 [3] 49, 65, 107 💬
|
16 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNG [1] IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 [1] 46 💬
|
17 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
18 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
ITGAL [1] ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
|
19 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
20 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
21 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
22 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
23 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
24 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
25 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
26 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
27 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
28 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Pimecrolimus Pimecrolimus 💬
| Pimecrolimus | 160 [1] 160 💬
|
29 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
30 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
31 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Voclosporin Voclosporin 💬
| Voclosporin | 049 [2] 49, 222 💬
|
32 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
33 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
SYK [1] SYK 💬
|
Fostamatinib Fostamatinib 💬
| Fostamatinib | 046 [4] 46, 49, 61, 66 💬
|
34 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
35 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
36 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
37 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
38 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
39 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
40 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
41 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
42 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
43 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
44 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
45 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
46 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Rontalizumab Rontalizumab 💬
| Rontalizumab | 049 [1] 49 💬
|
47 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Sifalimumab Sifalimumab 💬
| Sifalimumab | 049 [1] 49 💬
|
48 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Anifrolumab Anifrolumab 💬
| Anifrolumab | 046 [3] 46, 49, 53 💬
|
49 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
50 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
51 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
52 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon beta-1a Interferon beta-1a 💬
| Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬
|
53 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon beta-1b Interferon beta-1b 💬
| Interferon beta-1b | 013 [1] 13 💬
|
54 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Peginterferon beta-1a Peginterferon beta-1a 💬
| Peginterferon beta-1a | 013 [1] 13 💬
|
55 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNG [1] IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 [3] 49, 65, 107 💬
|
56 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNG [1] IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 [1] 46 💬
|
57 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬
|
58 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A [1] IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 [1] 51 💬
|
59 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A [2] IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
60 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
61 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
62 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
63 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬
|
Abrocitinib Abrocitinib 💬
| Abrocitinib | 084 [1] 84 💬
|
64 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬
|
Filgotinib Filgotinib 💬
| Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬
|
65 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬
|
Itacitinib Itacitinib 💬
| Itacitinib | 046 [4] 46, 51, 97, 228 💬
|
66 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
|
67 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
68 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [2] JAK1, JAK2 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 060 [3] 60, 65, 228 💬
|
69 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 [1] 46 💬
|
70 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
71 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
PARP1 [1] PARP1 💬
|
Olaparib Olaparib 💬
| Olaparib | 086 [2] 86, 285 💬
|
72 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
SMPD1 [1] SMPD1 💬
|
Olipudase alfa Olipudase alfa 💬
| Olipudase alfa | 019 [1] 19 💬
|
73 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
74 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
75 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
76 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
77 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
78 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
79 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
80 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
81 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
82 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
83 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TYK2 [1] TYK2 💬
|
Deucravacitinib Deucravacitinib 💬
| Deucravacitinib | 049 [3] 49, 96, 97 💬
|
84 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
85 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
86 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [4] ADORA1, ADORA2A, ADORA2B, ADORA3 💬
|
Adenosine Adenosine 💬
| Adenosine | 013 [3] 13, 58, 65 💬
|
87 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [4] ADORA1, ADORA2A, ADORA2B, ADORA3 💬
|
Adenosine phosphate Adenosine phosphate 💬
| Adenosine phosphate | 046 [1] 46 💬
|
88 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2B 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
89 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
90 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 [2] ADORA1, ADORA2B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
91 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA2A [1] ADORA2A 💬
|
Istradefylline Istradefylline 💬
| Istradefylline | 006 [1] 6 💬
|
92 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA2A [1] ADORA2A 💬
|
Preladenant Preladenant 💬
| Preladenant | 006 [1] 6 💬
|
93 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA2A [1] ADORA2A 💬
|
Regadenoson Regadenoson 💬
| Regadenoson | 058 [1] 58 💬
|
94 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA2A [1] ADORA2A 💬
|
Regadenoson Regadenoson 💬
| Regadenoson | 058 [1] 58 💬
|
95 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA2A [1] ADORA2A 💬
|
Tozadenant Tozadenant 💬
| Tozadenant | 006 [1] 6 💬
|
96 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA3 [1] ADORA3 💬
|
Piclidenoson Piclidenoson 💬
| Piclidenoson | 046 [1] 46 💬
|
97 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [1] ADRA1A 💬
|
Alfuzosin Alfuzosin 💬
| Alfuzosin | 013 [1] 13 💬
|
98 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [1] ADRA1A 💬
|
Silodosin Silodosin 💬
| Silodosin | 006 [2] 6 , 13 💬
|
99 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Doxazosin Doxazosin 💬
| Doxazosin | 057 [2] 57, 67 💬
|
100 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Midodrine Midodrine 💬
| Midodrine | 006 [3] 6 , 17, 58 💬
|
101 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Phenylephrine Phenylephrine 💬
| Phenylephrine | 022 [1] 22 💬
|
102 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Tamsulosin Tamsulosin 💬
| Tamsulosin | 013 [1] 13 💬
|
103 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
|
Terazosin Terazosin 💬
| Terazosin | 006 [1] 6 💬
|
104 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 [1] 280 💬
|
105 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬
|
Dipivefrin Dipivefrin 💬
| Dipivefrin | 006 [1] 6 💬
|
106 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬
|
Droxidopa Droxidopa 💬
| Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬
|
107 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬
|
Ephedrine Ephedrine 💬
| Ephedrine | 011 [1] 11 💬
|
108 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬
|
Epinephrine Epinephrine 💬
| Epinephrine | 046 [3] 46, 70, 96 💬
|
109 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬
|
Noradrenaline Noradrenaline 💬
| Norepinephrine | 022 [2] 22, 296 💬
|
110 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬
|
Pseudoephedrine Pseudoephedrine 💬
| Pseudoephedrine | 017 [1] 17 💬
|
111 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 [2] 28, 127 💬
|
112 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
|
Carvedilol Carvedilol 💬
| Carvedilol | 057 [4] 57, 86, 113, 210 💬
|
113 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬
|
Olanzapine Olanzapine 💬
| Olanzapine | 002 [2] 2 , 8 💬
|
114 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [1] ADRA2A 💬
|
Guanfacine Guanfacine 💬
| Guanfacine | 193 [1] 193 💬
|
115 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Apraclonidine Apraclonidine 💬
| Apraclonidine | 011 [1] 11 💬
|
116 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Brimonidine Brimonidine 💬
| Brimonidine | 013 [2] 13, 90 💬
|
117 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Clonidine Clonidine 💬
| Clonidine | 006 [4] 6 , 65, 70, 78 💬
|
118 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 [14] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
119 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Guanabenz Guanabenz 💬
| Guanabenz | 002 [2] 2 , 13 💬
|
120 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Rilmenidine Rilmenidine 💬
| Rilmenidine | 008 [1] 8 💬
|
121 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Tizanidine Tizanidine 💬
| Tizanidine | 013 [1] 13 💬
|
122 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬
|
Yohimbine Yohimbine 💬
| Yohimbine | 006 [1] 6 💬
|
123 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬
|
Chlorpromazine Chlorpromazine 💬
| Chlorpromazine | 254 [1] 254 💬
|
124 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [6] ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C 💬
|
Clozapine Clozapine 💬
| Clozapine | 006 [1] 6 💬
|
125 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A [2] ADRA2A, DRD2 💬
|
Pimozide Pimozide 💬
| Pimozide | 002 [1] 2 💬
|
126 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Atenolol Atenolol 💬
| Atenolol | 167 [1] 167 💬
|
127 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Bisoprolol Bisoprolol 💬
| Bisoprolol | 058 [4] 58, 67, 86, 113 💬
|
128 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Celiprolol Celiprolol 💬
| Celiprolol | 168 [1] 168 💬
|
129 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Dobutamine Dobutamine 💬
| Dobutamine | 057 [4] 57, 58, 86, 215 💬
|
130 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Esmolol Esmolol 💬
| Esmolol | 058 [1] 58 💬
|
131 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Metoprolol Metoprolol 💬
| Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬
|
132 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬
|
Nebivolol Nebivolol 💬
| Nebivolol | 017 [4] 17, 85, 113, 167 💬
|
133 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [2] ADRB1, ADRB2 💬
|
Nadolol Nadolol 💬
| Nadolol | 006 [1] 6 💬
|
134 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [2] ADRB1, ADRB2 💬
|
Timolol Timolol 💬
| Timolol | 157 [2] 157, 227 💬
|
135 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [2] ADRB1, ADRB2 💬
|
Timolol Timolol 💬
| Timolol | 157 [2] 157, 227 💬
|
136 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬
|
Propranolol Propranolol 💬
| Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬
|
137 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Clenbuterol Clenbuterol 💬
| Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬
|
138 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Formoterol Formoterol 💬
| Formoterol | 085 [3] 85, 228, 299 💬
|
139 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Isoxsuprine Isoxsuprine 💬
| Isoxsuprine | 013 [1] 13 💬
|
140 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Levosalbutamol Levosalbutamol 💬
| Levosalbutamol | 049 [1] 49 💬
|
141 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Albuterol Albuterol 💬
| Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
|
142 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Salmeterol Salmeterol 💬
| Salmeterol | 299 [1] 299 💬
|
143 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Terbutaline Terbutaline 💬
| Terbutaline | 118 [1] 118 💬
|
144 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬
|
Tulobuterol Tulobuterol 💬
| Tulobuterol | 006 [1] 6 💬
|
145 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB3 [1] ADRB3 💬
|
Mirabegron Mirabegron 💬
| Mirabegron | 006 [4] 6 , 13, 53, 226 💬
|
146 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Candesartan Candesartan 💬
| Candesartan | 058 [2] 58, 67 💬
|
147 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Candesartan cilexetil Candesartan cilexetil 💬
| Candesartan cilexetil | 067 [1] 67 💬
|
148 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Irbesartan Irbesartan 💬
| Irbesartan | 066 [4] 66, 167, 168, 222 💬
|
149 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
150 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Telmisartan Telmisartan 💬
| Telmisartan | 066 [2] 66, 67 💬
|
151 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Valsartan Valsartan 💬
| Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬
|
152 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [2] AGTR1, AGTR2 💬
|
Angiotensin II Angiotensin II 💬
| Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
|
153 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [2] AGTR1, AGTR2 💬
|
Angiotensin II Angiotensin II 💬
| Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
|
154 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [2] AGTR1, EDNRA 💬
|
Sparsentan Sparsentan 💬
| Sparsentan | 066 [3] 66, 218, 222 💬
|
155 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR1A [3] AVPR1A, AVPR1B, AVPR2 💬
|
Terlipressin Terlipressin 💬
| Terlipressin | 299 [1] 299 💬
|
156 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR1A [3] AVPR1A, AVPR1B, AVPR2 💬
|
Vasopressin Vasopressin 💬
| Vasopressin | 210 [1] 210 💬
|
157 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR1A [2] AVPR1A, AVPR2 💬
|
Conivaptan Conivaptan 💬
| Conivaptan | 086 [1] 86 💬
|
158 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬
|
Desmopressin Desmopressin 💬
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬
|
159 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬
|
Lixivaptan Lixivaptan 💬
| Lixivaptan | 067 [1] 67 💬
|
160 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬
|
Tolvaptan Tolvaptan 💬
| Tolvaptan | 067 [4] 67, 72, 86, 225 💬
|
161 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
162 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Crovalimab Crovalimab 💬
| Crovalimab | 062 [2] 62, 109 💬
|
163 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Eculizumab Eculizumab 💬
| Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬
|
164 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Nomacopan Nomacopan 💬
| Nomacopan | 062 [3] 62, 109, 162 💬
|
165 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Pozelimab Pozelimab 💬
| Pozelimab | 011 [2] 11, 62 💬
|
166 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
167 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Vilobelimab Vilobelimab 💬
| Vilobelimab | 043 [3] 43, 44, 269 💬
|
168 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
169 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5AR1 [1] C5AR1 💬
|
Avacopan Avacopan 💬
| Avacopan | 043 [3] 43, 44, 222 💬
|
170 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CALCA [1] CALCA 💬
|
Fremanezumab Fremanezumab 💬
| Fremanezumab | 124 [2] 124, 226 💬
|
171 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CCKBR [1] CCKBR 💬
|
Proglumide Proglumide 💬
| Proglumide | 298 [1] 298 💬
|
172 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 [2] 2 , 299 💬
|
173 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Blarcamesine Blarcamesine 💬
| Blarcamesine | 156 [1] 156 💬
|
174 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Oxybutynin Oxybutynin 💬
| Oxybutynin | 006 [3] 6 , 13, 53 💬
|
175 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Propiverine Propiverine 💬
| Propiverine | 226 [1] 226 💬
|
176 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 [1] 2 💬
|
177 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Trihexyphenidyl Trihexyphenidyl 💬
| Trihexyphenidyl | 005 [2] 5 , 6 💬
|
178 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Tropicamide Tropicamide 💬
| Tropicamide | 006 [1] 6 💬
|
179 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM2 [2] CHRM2, CHRM3 💬
|
Fesoterodine Fesoterodine 💬
| Fesoterodine | 006 [1] 6 💬
|
180 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM2 [2] CHRM2, CHRM3 💬
|
Pilocarpine Pilocarpine 💬
| Pilocarpine | 006 [3] 6 , 53, 299 💬
|
181 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM3 [1] CHRM3 💬
|
Cevimeline Cevimeline 💬
| Cevimeline | 053 [1] 53 💬
|
182 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM3 [1] CHRM3 💬
|
Darifenacin Darifenacin 💬
| Darifenacin | 006 [2] 6 , 13 💬
|
183 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM3 [1] CHRM3 💬
|
Solifenacin Solifenacin 💬
| Solifenacin | 006 [3] 6 , 13, 53 💬
|
184 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRM3 [1] CHRM3 💬
|
Tolterodine Tolterodine 💬
| Tolterodine | 017 [2] 17, 53 💬
|
185 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRNA1 [16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG 💬
|
Nicotine Nicotine 💬
| Nicotine | 006 [3] 6 , 13, 84 💬
|
186 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRNA4 [2] CHRNA4, CHRNB2 💬
|
Varenicline Varenicline 💬
| Varenicline | 006 [3] 6 , 18, 53 💬
|
187 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [1] CNR1 💬
|
Rimonabant Rimonabant 💬
| Rimonabant | 193 [1] 193 💬
|
188 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Cannabidiol Cannabidiol 💬
| Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
|
189 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Dronabinol Dronabinol 💬
| Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
|
190 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬
|
Nabilone Nabilone 💬
| Nabilone | 006 [3] 6 , 13, 127 💬
|
191 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR2 [1] CNR2 💬
|
Lenabasum Lenabasum 💬
| Ajulemic acid | 050 [3] 50, 51, 299 💬
|
192 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CRHR1 [2] CRHR1, CRHR2 💬
|
Corticorelin Corticorelin 💬
| Corticorelin | 075 [1] 75 💬
|
193 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CRHR1 [2] CRHR1, CRHR2 💬
|
Corticorelin ovine triflutate Corticorelin ovine triflutate 💬
| Corticorelin ovine triflutate | 075 [1] 75 💬
|
194 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Montelukast Montelukast 💬
| Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬
|
195 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [1] CYSLTR1 💬
|
Tipelukast Tipelukast 💬
| Tipelukast | 085 [1] 85 💬
|
196 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 [2] CYSLTR1, PTGIR 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
197 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Apomorphine Apomorphine 💬
| Apomorphine | 005 [3] 5 , 6 , 7 💬
|
198 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Flupentixol Flupentixol 💬
| Flupentixol | 097 [1] 97 💬
|
199 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [2] DRD1, DRD2 💬
|
Pergolide Pergolide 💬
| Pergolide | 006 [1] 6 💬
|
200 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬
|
Dexpramipexole Dexpramipexole 💬
| Dexpramipexole | 002 [1] 2 💬
|
201 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬
|
Dopamine Dopamine 💬
| Dopamine | 006 [4] 6 , 7 , 74, 299 💬
|
202 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬
|
Foslevodopa Foslevodopa 💬
| Foslevodopa | 006 [1] 6 💬
|
203 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬
|
Levodopa Levodopa 💬
| Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬
|
204 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [2] DRD1, DRD5 💬
|
Tavapadon Tavapadon 💬
| Tavapadon | 006 [1] 6 💬
|
205 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Domperidone Domperidone 💬
| Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬
|
206 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Domperidone maleate Domperidone maleate 💬
| Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬
|
207 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Haloperidol Haloperidol 💬
| Haloperidol | 008 [1] 8 💬
|
208 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Melperone Melperone 💬
| Melperone | 006 [1] 6 💬
|
209 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Metoclopramide Metoclopramide 💬
| Metoclopramide | 046 [2] 46, 51 💬
|
210 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Pridopidine Pridopidine 💬
| Pridopidine | 002 [3] 2 , 6 , 8 💬
|
211 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Rotigotine Rotigotine 💬
| Rotigotine | 006 [1] 6 💬
|
212 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Sulpiride Sulpiride 💬
| Sulpiride | 006 [2] 6 , 70 💬
|
213 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Tiapride Tiapride 💬
| Tiapride | 008 [1] 8 💬
|
214 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Trifluoperazine maleate Trifluoperazine maleate 💬
| Trifluoperazine | 283 [2] 283, 284 💬
|
215 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [1] DRD2 💬
|
Trifluoperazine Trifluoperazine 💬
| Trifluoperazine | 283 [2] 283, 284 💬
|
216 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, DRD3 💬
|
Piribedil Piribedil 💬
| Piribedil | 006 [1] 6 💬
|
217 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Lisuride Lisuride 💬
| Lisuride | 006 [2] 6 , 86 💬
|
218 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Pramipexole Pramipexole 💬
| Pramipexole | 002 [3] 2 , 6 , 20 💬
|
219 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬
|
Ropinirole Ropinirole 💬
| Ropinirole | 002 [4] 2 , 6 , 74, 309 💬
|
220 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, DRD3, HTR1A 💬
|
Pardoprunox Pardoprunox 💬
| Pardoprunox | 006 [1] 6 💬
|
221 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [4] DRD2, DRD3, HTR1A, HTR2A 💬
|
Aripiprazole Aripiprazole 💬
| Aripiprazole | 006 [2] 6 , 206 💬
|
222 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, HTR1A 💬
|
Buspirone Buspirone 💬
| Buspirone | 006 [2] 6 , 51 💬
|
223 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [3] DRD2, HTR1A, HTR2A 💬
|
Cariprazine Cariprazine 💬
| Cariprazine | 021 [1] 21 💬
|
224 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Quetiapine Quetiapine 💬
| Quetiapine | 006 [2] 6 , 13 💬
|
225 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
226 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬
|
Iloperidone Iloperidone 💬
| Iloperidone | 006 [1] 6 💬
|
227 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, PRL 💬
|
Bromocriptine Bromocriptine 💬
| Bromocriptine | 006 [2] 6 , 74 💬
|
228 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, PRL 💬
|
Cabergoline Cabergoline 💬
| Cabergoline | 006 [3] 6 , 74, 75 💬
|
229 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, PRL 💬
|
Terguride Terguride 💬
| Terguride | 051 [2] 51, 86 💬
|
230 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [1] EDNRA 💬
|
Ambrisentan Ambrisentan 💬
| Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
|
231 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [1] EDNRA 💬
|
Sitaxentan Sitaxentan 💬
| Sitaxentan | 086 [1] 86 💬
|
232 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [1] EDNRA 💬
|
Zibotentan Zibotentan 💬
| Zibotentan | 051 [1] 51 💬
|
233 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
234 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
235 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬
|
Macitentan Macitentan 💬
| Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
|
236 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬
|
237 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Dabigatran etexilate Dabigatran etexilate 💬
| Dabigatran etexilate | 051 [2] 51, 75 💬
|
238 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
F2 [1] F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 [1] 85 💬
|
239 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Arbaclofen Arbaclofen 💬
| Arbaclofen | 013 [2] 13, 206 💬
|
240 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Arbaclofen placarbil Arbaclofen placarbil 💬
| Arbaclofen Placarbil | 013 [1] 13 💬
|
241 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬
| Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
|
242 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABBR1 [2] GABBR1, GABBR2 💬
|
Valiloxybate Valiloxybate 💬
| Valiloxybate | 006 [1] 6 💬
|
243 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [1] GABRA1 💬
|
Etomidate Etomidate 💬
| Etomidate | 006 [1] 6 💬
|
244 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
245 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Brexanolone Brexanolone 💬
| Brexanolone | 205 [1] 205 💬
|
246 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Clobazam Clobazam 💬
| Clobazam | 140 [2] 140, 144 💬
|
247 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Clonazepam Clonazepam 💬
| Clonazepam | 006 [1] 6 💬
|
248 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Delorazepam Delorazepam 💬
| Delorazepam | 006 [3] 6 , 46, 97 💬
|
249 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Diazepam Diazepam 💬
| Diazepam | 046 [3] 46, 155, 298 💬
|
250 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Eszopiclone Eszopiclone 💬
| Eszopiclone | 006 [3] 6 , 13, 46 💬
|
251 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Flumazenil Flumazenil 💬
| Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬
|
252 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Gaboxadol Gaboxadol 💬
| Gaboxadol | 201 [2] 201, 206 💬
|
253 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Ganaxolone Ganaxolone 💬
| Ganaxolone | 145 [4] 145, 152, 158, 206 💬
|
254 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Lorazepam Lorazepam 💬
| Lorazepam | 036 [1] 36 💬
|
255 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
256 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
257 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Zolpidem Zolpidem 💬
| Zolpidem | 005 [3] 5 , 6 , 46 💬
|
258 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Zopiclone Zopiclone 💬
| Zopiclone | 006 [1] 6 💬
|
259 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [25] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬
|
260 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR [1] GHR 💬
|
Lonapegsomatropin Lonapegsomatropin 💬
| Lonapegsomatropin | 078 [1] 78 💬
|
261 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR [1] GHR 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
262 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR [1] GHR 💬
|
Pegvisomant Pegvisomant 💬
| Pegvisomant | 078 [2] 78, 265 💬
|
263 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR [1] GHR 💬
|
Somapacitan Somapacitan 💬
| Somapacitan | 078 [2] 78, 195 💬
|
264 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR [1] GHR 💬
|
Somavaratan Somavaratan 💬
| Somavaratan | 078 [1] 78 💬
|
265 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHRHR [1] GHRHR 💬
|
Somatorelin Somatorelin 💬
| Somatorelin | 013 [2] 13, 78 💬
|
266 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHRHR [1] GHRHR 💬
|
Tesamorelin Tesamorelin 💬
| Tesamorelin | 078 [2] 78, 265 💬
|
267 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHSR [1] GHSR 💬
|
Macimorelin Macimorelin 💬
| Macimorelin | 078 [1] 78 💬
|
268 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GIPR [2] GIPR, GLP1R 💬
|
Tirzepatide Tirzepatide 💬
| Tirzepatide | 233 [1] 233 💬
|
269 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GLP1R [1] GLP1R 💬
|
Dulaglutide Dulaglutide 💬
| Dulaglutide | 013 [2] 13, 299 💬
|
270 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GLP1R [1] GLP1R 💬
|
Exenatide Exenatide 💬
| Exenatide | 006 [6] 6 , 17, 72, 78, 193, 233 💬
|
271 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GLP1R [1] GLP1R 💬
|
Liraglutide Liraglutide 💬
| Liraglutide | 006 [3] 6 , 75, 193 💬
|
272 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GLP1R [1] GLP1R 💬
|
Lixisenatide Lixisenatide 💬
| Lixisenatide | 006 [1] 6 💬
|
273 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GLP1R [1] GLP1R 💬
|
Semaglutide Semaglutide 💬
| Semaglutide | 006 [1] 6 💬
|
274 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GLP2R [1] GLP2R 💬
|
Teduglutide Teduglutide 💬
| Teduglutide | 096 [1] 96 💬
|
275 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GNRHR [1] GNRHR 💬
|
Cetrorelix Cetrorelix 💬
| Cetrorelix | 046 [1] 46 💬
|
276 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GNRHR [1] GNRHR 💬
|
Gonadorelin Gonadorelin 💬
| Gonadorelin | 076 [1] 76 💬
|
277 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GNRHR [1] GNRHR 💬
|
Goserelin Goserelin 💬
| Goserelin | 001 [1] 1 💬
|
278 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GNRHR [1] GNRHR 💬
|
Histrelin Histrelin 💬
| Histrelin | 076 [1] 76 💬
|
279 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GNRHR [1] GNRHR 💬
|
Triptorelin Triptorelin 💬
| Triptorelin | 049 [2] 49, 76 💬
|
280 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
281 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
282 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
283 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Acamprosate Acamprosate 💬
| Acamprosate | 006 [2] 6 , 206 💬
|
284 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
285 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
286 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
287 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
288 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
289 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
290 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HCRTR1 [2] HCRTR1, HCRTR2 💬
|
Suvorexant Suvorexant 💬
| Suvorexant | 005 [3] 5 , 6 , 13 💬
|
291 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Cetirizine Cetirizine 💬
| Cetirizine | 013 [4] 13, 28, 35, 300 💬
|
292 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Chlorphenamine Chlorphenamine 💬
| Chlorpheniramine | 014 [1] 14 💬
|
293 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Clemastine Clemastine 💬
| Clemastine | 013 [1] 13 💬
|
294 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Desloratadine Desloratadine 💬
| Desloratadine | 013 [1] 13 💬
|
295 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Dexchlorpheniramine Dexchlorpheniramine 💬
| Dexchlorpheniramine | 013 [2] 13, 49 💬
|
296 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Diphenhydramine Diphenhydramine 💬
| Diphenhydramine | 011 [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
|
297 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Doxepin Doxepin 💬
| Doxepin | 006 [1] 6 💬
|
298 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Fexofenadine Fexofenadine 💬
| Fexofenadine | 013 [2] 13, 46 💬
|
299 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Levocetirizine Levocetirizine 💬
| Levocetirizine | 061 [1] 61 💬
|
300 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Loratadine Loratadine 💬
| Loratadine | 013 [4] 13, 46, 89, 98 💬
|
301 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬
|
Promethazine Promethazine 💬
| Promethazine | 096 [1] 96 💬
|
302 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [2] HRH1, PTAFR 💬
|
Rupatadine Rupatadine 💬
| Rupatadine | 046 [1] 46 💬
|
303 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH2 [1] HRH2 💬
|
Cimetidine Cimetidine 💬
| Cimetidine | 002 [2] 2 , 254 💬
|
304 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH2 [1] HRH2 💬
|
Famotidine Famotidine 💬
| Famotidine | 006 [6] 6 , 46, 61, 86, 98, 107 💬
|
305 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH2 [1] HRH2 💬
|
Ranitidine Ranitidine 💬
| Ranitidine | 013 [2] 13, 65 💬
|
306 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH3 [1] HRH3 💬
|
Bavisant Bavisant 💬
| Bavisant | 006 [1] 6 💬
|
307 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH3 [1] HRH3 💬
|
Pitolisant Pitolisant 💬
| Pitolisant | 006 [3] 6 , 113, 193 💬
|
308 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR1A [1] HTR1A 💬
|
Vortioxetine Vortioxetine 💬
| Vortioxetine | 006 [1] 6 💬
|
309 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR1B [2] HTR1B, HTR1D 💬
|
Zolmitriptan Zolmitriptan 💬
| Zolmitriptan | 006 [1] 6 💬
|
310 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR1D [3] HTR1D, HTR2A, HTR2C 💬
|
Fenfluramine Fenfluramine 💬
| Fenfluramine | 140 [4] 140, 144, 145, 149 💬
|
311 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR2A [1] HTR2A 💬
|
Nelotanserin Nelotanserin 💬
| Nelotanserin | 006 [1] 6 💬
|
312 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬
|
Trazodone Trazodone 💬
| Trazodone | 002 [1] 2 💬
|
313 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR2A [2] HTR2A, HTR4 💬
|
Cisapride Cisapride 💬
| Cisapride | 013 [1] 13 💬
|
314 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR2A [2] HTR2A, HTR4 💬
|
Cisapride Cisapride 💬
| Cisapride | 013 [1] 13 💬
|
315 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR2C [3] HTR2C, MTNR1A, MTNR1B 💬
|
Agomelatine Agomelatine 💬
| Agomelatine | 006 [1] 6 💬
|
316 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR4 [1] HTR4 💬
|
Mosapride Mosapride 💬
| Mosapride | 096 [1] 96 💬
|
317 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR4 [1] HTR4 💬
|
Prucalopride Prucalopride 💬
| Prucalopride | 013 [3] 13, 51, 96 💬
|
318 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR4 [1] HTR4 💬
|
Velusetrag Velusetrag 💬
| Velusetrag | 099 [1] 99 💬
|
319 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
LEPR [1] LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 [1] 265 💬
|
320 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC1R [1] MC1R 💬
|
Afamelanotide Afamelanotide 💬
| Afamelanotide | 159 [3] 159, 161, 254 💬
|
321 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC2R [1] MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 [12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
322 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC2R [1] MC2R 💬
|
Cosyntropin Cosyntropin 💬
| Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬
|
323 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC4R [1] MC4R 💬
|
Setmelanotide Setmelanotide 💬
| Setmelanotide | 202 [2] 202, 265 💬
|
324 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Melatonin Melatonin 💬
| Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
|
325 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Ramelteon Ramelteon 💬
| Ramelteon | 006 [3] 6 , 8 , 46 💬
|
326 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
|
Tasimelteon Tasimelteon 💬
| Tasimelteon | 202 [1] 202 💬
|
327 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Beclomethasone dipropionate Beclomethasone dipropionate 💬
| Beclomethasone dipropionate | 085 [3] 85, 97, 98 💬
|
328 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Betamethasone Betamethasone 💬
| Betamethasone | 002 [8] 2 , 28, 46, 65, 83, 90, 96, 235 💬
|
329 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Budesonide Budesonide 💬
| Budesonide | 066 [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
|
330 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Ciclesonide Ciclesonide 💬
| Ciclesonide | 084 [1] 84 💬
|
331 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Clobetasol Clobetasol 💬
| Clobetasol | 039 [4] 39, 46, 51, 162 💬
|
332 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Clobetasol propionate Clobetasol propionate 💬
| Clobetasol propionate | 046 [2] 46, 162 💬
|
333 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Cortisone Cortisone 💬
| Cortisone | 081 [1] 81 💬
|
334 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Cortisone acetate Cortisone acetate 💬
| Cortisone acetate | 081 [1] 81 💬
|
335 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Deflazacort Deflazacort 💬
| Deflazacort | 030 [2] 30, 113 💬
|
336 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Dexamethasone Dexamethasone 💬
| Dexamethasone | 013 [22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
|
337 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Fluocinolone acetonide Fluocinolone acetonide 💬
| Fluocinolone acetonide | 090 [1] 90 💬
|
338 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Fluticasone Fluticasone 💬
| Fluticasone | 098 [3] 98, 228, 299 💬
|
339 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Fluticasone propionate Fluticasone propionate 💬
| Fluticasone propionate | 098 [2] 98, 228 💬
|
340 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Halometasone Halometasone 💬
| Halometasone | 162 [1] 162 💬
|
341 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Hydrocortisone Hydrocortisone 💬
| Hydrocortisone | 006 [10] 6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
|
342 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Hydrocortisone acetate Hydrocortisone acetate 💬
| Hydrocortisone acetate | 097 [1] 97 💬
|
343 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Hydrocortisone cypionate Hydrocortisone cypionate 💬
| Hydrocortisone cypionate | 006 [3] 6 , 81, 83 💬
|
344 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Hydrocortisone succinate Hydrocortisone succinate 💬
| Hydrocortisone succinate | 006 [3] 6 , 81, 83 💬
|
345 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Methylprednisolone Methylprednisolone 💬
| Methylprednisolone | 002 [46] 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
|
346 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Methylprednisolone hemisuccinate Methylprednisolone hemisuccinate 💬
| Methylprednisolone hemisuccinate | 013 [7] 13, 49, 50, 51, 53, 97, 211 💬
|
347 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Mifepristone Mifepristone 💬
| Mifepristone | 075 [1] 75 💬
|
348 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Mometasone Mometasone 💬
| Mometasone | 098 [2] 98, 162 💬
|
349 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Mometasone furoate Mometasone furoate 💬
| Mometasone furoate | 098 [2] 98, 162 💬
|
350 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisolone Prednisolone 💬
| Prednisolone | 003 [42] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
|
351 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisolone acetate Prednisolone acetate 💬
| Prednisolone acetate | 222 [1] 222 💬
|
352 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisone Prednisone 💬
| Prednisone | 002 [45] 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
|
353 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisone acetate Prednisone acetate 💬
| Prednisone acetate | 035 [6] 35, 41, 46, 49, 162, 224 💬
|
354 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Relacorilant Relacorilant 💬
| Relacorilant | 075 [1] 75 💬
|
355 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Triamcinolone Triamcinolone 💬
| Triamcinolone | 035 [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
|
356 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Vamorolone Vamorolone 💬
| Vamorolone | 097 [2] 97, 113 💬
|
357 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Loperamide Loperamide 💬
| Loperamide | 013 [2] 13, 97 💬
|
358 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Nalbuphine Nalbuphine 💬
| Nalbuphine | 085 [1] 85 💬
|
359 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Nalmefene Nalmefene 💬
| Nalmefene | 006 [1] 6 💬
|
360 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Naloxone Naloxone 💬
| Naloxone | 006 [2] 6 , 226 💬
|
361 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
362 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬
|
Oxycodone Oxycodone 💬
| Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬
|
363 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRK1 [2] OPRK1, OPRM1 💬
|
Buprenorphine Buprenorphine 💬
| Buprenorphine | 046 [2] 46, 70 💬
|
364 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRK1 [2] OPRK1, OPRM1 💬
|
Dezocine Dezocine 💬
| Dezocine | 046 [1] 46 💬
|
365 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRK1 [2] OPRK1, OPRM1 💬
|
Trimebutine Trimebutine 💬
| Trimebutine | 051 [1] 51 💬
|
366 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Dihydrocodeine Dihydrocodeine 💬
| Dihydrocodeine | 310 [1] 310 💬
|
367 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Fentanyl Fentanyl 💬
| Fentanyl | 046 [3] 46, 70, 215 💬
|
368 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Hydromorphone Hydromorphone 💬
| Hydromorphone | 070 [1] 70 💬
|
369 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Morphine Morphine 💬
| Morphine | 036 [5] 36, 46, 70, 85, 86 💬
|
370 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Oxymorphone Oxymorphone 💬
| Oxymorphone | 070 [1] 70 💬
|
371 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Remifentanil Remifentanil 💬
| Remifentanil | 006 [2] 6 , 70 💬
|
372 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Sufentanil Sufentanil 💬
| Sufentanil | 070 [2] 70, 280 💬
|
373 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 [1] OPRM1 💬
|
Tramadol Tramadol 💬
| Tramadol | 046 [5] 46, 70, 78, 226, 271 💬
|
374 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OXTR [1] OXTR 💬
|
Atosiban Atosiban 💬
| Atosiban | 118 [1] 118 💬
|
375 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OXTR [1] OXTR 💬
|
Oxytocin Oxytocin 💬
| Oxytocin | 006 [7] 6 , 72, 127, 168, 193, 206, 226 💬
|
376 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
P2RX3 [1] P2RX3 💬
|
Gefapixant Gefapixant 💬
| Gefapixant | 085 [2] 85, 226 💬
|
377 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PLG [1] PLG 💬
|
Aminocaproic acid Aminocaproic acid 💬
| Aminocaproic acid | 070 [1] 70 💬
|
378 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PLG [1] PLG 💬
|
Tranexamic acid Tranexamic acid 💬
| Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬
|
379 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGDR [2] PTGDR, TBXA2R 💬
|
Ramatroban Ramatroban 💬
| Ramatroban | 013 [1] 13 💬
|
380 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGER1 [1] PTGER1 💬
|
Alprostadil Alprostadil 💬
| Alprostadil | 051 [2] 51, 70 💬
|
381 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGER1 [1] PTGER1 💬
|
Limaprost Limaprost 💬
| Limaprost | 070 [1] 70 💬
|
382 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGER2 [3] PTGER2, PTGER3, PTGER4 💬
|
Misoprostol Misoprostol 💬
| Misoprostol | 046 [3] 46, 70, 271 💬
|
383 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGFR [1] PTGFR 💬
|
Tafluprost Tafluprost 💬
| Tafluprost | 299 [1] 299 💬
|
384 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGFR [1] PTGFR 💬
|
Unoprostone Unoprostone 💬
| Unoprostone | 090 [1] 90 💬
|
385 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Beraprost Beraprost 💬
| Beraprost | 086 [1] 86 💬
|
386 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Epoprostenol Epoprostenol 💬
| Epoprostenol | 086 [1] 86 💬
|
387 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Iloprost Iloprost 💬
| Iloprost | 051 [4] 51, 84, 85, 86 💬
|
388 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Ralinepag Ralinepag 💬
| Ralinepag | 086 [1] 86 💬
|
389 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Selexipag Selexipag 💬
| Selexipag | 051 [5] 51, 70, 84, 86, 88 💬
|
390 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR [1] PTGIR 💬
|
Treprostinil Treprostinil 💬
| Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
|
391 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTH1R [1] PTH1R 💬
|
Teriparatide Teriparatide 💬
| Teriparatide | 046 [7] 46, 65, 68, 70, 71, 235, 274 💬
|
392 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTH1R [2] PTH1R, PTH2R 💬
|
Parathyroid hormone Parathyroid hormone 💬
| Parathyroid hormone | 065 [4] 65, 70, 235, 326 💬
|
393 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [1] S1PR1 💬
|
Cenerimod Cenerimod 💬
| Cenerimod | 049 [1] 49 💬
|
394 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [1] S1PR1 💬
|
Fingolimod Fingolimod 💬
| Fingolimod | 013 [3] 13, 14, 156 💬
|
395 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [1] S1PR1 💬
|
Ponesimod Ponesimod 💬
| Ponesimod | 013 [1] 13 💬
|
396 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Amiselimod Amiselimod 💬
| Amiselimod | 097 [1] 97 💬
|
397 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Etrasimod Etrasimod 💬
| Etrasimod | 096 [3] 96, 97, 98 💬
|
398 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬
|
Ozanimod Ozanimod 💬
| Ozanimod | 013 [3] 13, 96, 97 💬
|
399 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 [2] S1PR1, S1PR5 💬
|
Siponimod Siponimod 💬
| Siponimod | 013 [2] 13, 50 💬
|
400 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR1 [5] SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 💬
|
Somatostatin Somatostatin 💬
| Somatostatin | 067 [2] 67, 78 💬
|
401 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR1 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬
|
Pasireotide Pasireotide 💬
| Pasireotide | 067 [3] 67, 74, 75 💬
|
402 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR2 [1] SSTR2 💬
|
Octreotide Octreotide 💬
| Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬
|
403 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TACR1 [1] TACR1 💬
|
Orvepitant Orvepitant 💬
| Orvepitant | 085 [1] 85 💬
|
404 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TACR1 [1] TACR1 💬
|
Serlopitant Serlopitant 💬
| Serlopitant | 036 [1] 36 💬
|
405 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TBXA2R [1] TBXA2R 💬
|
Cilostazol Cilostazol 💬
| Cilostazol | 046 [3] 46, 51, 70 💬
|
406 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TBXA2R [1] TBXA2R 💬
|
Ifetroban Ifetroban 💬
| Ifetroban | 085 [2] 85, 113 💬
|
407 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
THRA [2] THRA, THRB 💬
|
Levothyroxine Levothyroxine 💬
| Levothyroxine | 019 [5] 19, 49, 78, 80, 222 💬
|
408 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
THRA [2] THRA, THRB 💬
|
Liothyronine Liothyronine 💬
| Liothyronine | 013 [4] 13, 78, 210, 212 💬
|
409 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
THRA [2] THRA, THRB 💬
|
Tiratricol Tiratricol 💬
| Tiratricol | 078 [2] 78, 139 💬
|
410 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
THRB [1] THRB 💬
|
Sobetirome Sobetirome 💬
| Sobetirome | 020 [1] 20 💬
|
411 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TRHR [1] TRHR 💬
|
Protirelin Protirelin 💬
| Protirelin | 080 [1] 80 💬
|
412 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
TRPV1 [1] TRPV1 💬
|
Capsaicin Capsaicin 💬
| Capsaicin | 006 [3] 6 , 86, 226 💬
|
413 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
414 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
415 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
416 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
417 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬
|
418 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 [3] 6 , 89, 272 💬
|
419 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
420 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
421 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF [2] BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
422 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
423 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
424 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
425 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
426 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
427 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP3K5 [1] MAP3K5 💬
|
Selonsertib Selonsertib 💬
| Selonsertib | 086 [1] 86 💬
|
428 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
429 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
430 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
431 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
NGF [1] NGF 💬
|
Tanezumab Tanezumab 💬
| Tanezumab | 226 [2] 226, 298 💬
|
432 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
NGFR [1] NGFR 💬
|
Cenegermin Cenegermin 💬
| Cenegermin | 053 [2] 53, 90 💬
|
433 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
434 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
435 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
436 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
PRKCD [1] PRKCD 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 [1] 97 💬
|
437 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
PSEN1 [1] PSEN1 💬
|
Tarenflurbil Tarenflurbil 💬
| Tarenflurbil | 013 [1] 13 💬
|
438 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
439 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
SORT1 [1] SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 [2] 2 , 127 💬
|
440 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C3 [1] C3 💬
|
Pegcetacoplan Pegcetacoplan 💬
| Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬
|
441 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Crovalimab Crovalimab 💬
| Crovalimab | 062 [2] 62, 109 💬
|
442 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Eculizumab Eculizumab 💬
| Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬
|
443 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Nomacopan Nomacopan 💬
| Nomacopan | 062 [3] 62, 109, 162 💬
|
444 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Pozelimab Pozelimab 💬
| Pozelimab | 011 [2] 11, 62 💬
|
445 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬
|
446 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Vilobelimab Vilobelimab 💬
| Vilobelimab | 043 [3] 43, 44, 269 💬
|
447 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 [1] C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 [3] 2 , 11, 62 💬
|
448 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5AR1 [1] C5AR1 💬
|
Avacopan Avacopan 💬
| Avacopan | 043 [3] 43, 44, 222 💬
|
449 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
ELANE [1] ELANE 💬
|
Sivelestat Sivelestat 💬
| Sivelestat | 013 [3] 13, 85, 96 💬
|
450 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
HDAC1 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬
|
Vorinostat Vorinostat 💬
| Vorinostat | 075 [2] 75, 96 💬
|
451 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
ITGAL [1] ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
|
452 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
453 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
454 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
455 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
456 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
457 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
458 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
459 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MPO [1] MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 [3] 2 , 17, 127 💬
|
460 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
461 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
462 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 [1] 13 💬
|
463 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
464 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
465 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
466 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
467 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
468 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
RAF1 [1] RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
469 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
470 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
471 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
472 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
473 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 [3] 6 , 89, 272 💬
|
474 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SYK [1] SYK 💬
|
Fostamatinib Fostamatinib 💬
| Fostamatinib | 046 [4] 46, 49, 61, 66 💬
|
475 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
TLR7 [1] TLR7 💬
|
Imiquimod Imiquimod 💬
| Imiquimod | 034 [2] 34, 51 💬
|
476 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
VWF [1] VWF 💬
|
Caplacizumab Caplacizumab 💬
| Caplacizumab | 064 [1] 64 💬
|
477 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
478 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Acalabrutinib Acalabrutinib 💬
| Acalabrutinib | 046 [2] 46, 61 💬
|
479 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Branebrutinib Branebrutinib 💬
| Branebrutinib | 046 [3] 46, 49, 53 💬
|
480 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Evobrutinib Evobrutinib 💬
| Evobrutinib | 013 [3] 13, 46, 49 💬
|
481 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Fenebrutinib Fenebrutinib 💬
| Fenebrutinib | 013 [1] 13 💬
|
482 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Ibrutinib Ibrutinib 💬
| Ibrutinib | 028 [3] 28, 60, 61 💬
|
483 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Orelabrutinib Orelabrutinib 💬
| Orelabrutinib | 013 [4] 13, 49, 61, 63 💬
|
484 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Remibrutinib Remibrutinib 💬
| Remibrutinib | 013 [2] 13, 53 💬
|
485 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK [1] BTK 💬
|
Zanubrutinib Zanubrutinib 💬
| Zanubrutinib | 013 [5] 13, 63, 222, 300, 331 💬
|
486 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40 [1] CD40 💬
|
Bleselumab Bleselumab 💬
| Bleselumab | 222 [1] 222 💬
|
487 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40 [1] CD40 💬
|
Iscalimab Iscalimab 💬
| Iscalimab | 049 [2] 49, 53 💬
|
488 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40 [1] CD40 💬
|
Ravagalimab Ravagalimab 💬
| Ravagalimab | 053 [2] 53, 97 💬
|
489 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40LG [1] CD40LG 💬
|
Toralizumab Toralizumab 💬
| Toralizumab | 063 [1] 63 💬
|
490 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
491 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
492 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
493 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [2] IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
494 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
495 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
496 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK [1] LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
497 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA [1] LTA 💬
|
Pateclizumab Pateclizumab 💬
| Pateclizumab | 046 [1] 46 💬
|
498 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
499 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTB [1] LTB 💬
|
Baminercept Baminercept 💬
| Baminercept | 013 [4] 13, 46, 53, 97 💬
|
500 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
501 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PARP1 [1] PARP1 💬
|
Olaparib Olaparib 💬
| Olaparib | 086 [2] 86, 285 💬
|
502 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
503 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PRKCQ [1] PRKCQ 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 [1] 97 💬
|
504 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Aceclofenac Aceclofenac 💬
| Aceclofenac | 046 [1] 46 💬
|
505 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
506 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Aspirin Aspirin 💬
| Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
|
507 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
508 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬
|
509 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Diflunisal Diflunisal 💬
| Diflunisal | 028 [1] 28 💬
|
510 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Etodolac Etodolac 💬
| Etodolac | 046 [1] 46 💬
|
511 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Etoricoxib Etoricoxib 💬
| Etoricoxib | 046 [2] 46, 271 💬
|
512 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Flurbiprofen Flurbiprofen 💬
| Flurbiprofen | 013 [3] 13, 21, 46 💬
|
513 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Ibuprofen Ibuprofen 💬
| Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬
|
514 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Indomethacin Indomethacin 💬
| Indomethacin | 225 [3] 225, 271, 298 💬
|
515 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Ketoprofen Ketoprofen 💬
| Ketoprofen | 046 [1] 46 💬
|
516 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Ketorolac Ketorolac 💬
| Ketorolac | 070 [2] 70, 226 💬
|
517 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Loxoprofen Loxoprofen 💬
| Loxoprofen | 046 [2] 46, 271 💬
|
518 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Lumiracoxib Lumiracoxib 💬
| Lumiracoxib | 046 [1] 46 💬
|
519 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Meloxicam Meloxicam 💬
| Meloxicam | 046 [4] 46, 49, 271, 296 💬
|
520 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Naproxen Naproxen 💬
| Naproxen | 013 [4] 13, 46, 107, 271 💬
|
521 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Nimesulide Nimesulide 💬
| Nimesulide | 046 [1] 46 💬
|
522 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Parecoxib Parecoxib 💬
| Parecoxib | 046 [2] 46, 271 💬
|
523 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Rofecoxib Rofecoxib 💬
| Rofecoxib | 046 [1] 46 💬
|
524 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Salsalate Salsalate 💬
| Salsalate | 005 [1] 5 💬
|
525 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Sulindac Sulindac 💬
| Sulindac | 206 [1] 206 💬
|
526 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Tolfenamic acid Tolfenamic acid 💬
| Tolfenamic acid | 005 [1] 5 💬
|
527 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬
|
Valdecoxib Valdecoxib 💬
| Valdecoxib | 046 [1] 46 💬
|
528 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
529 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
SYK [1] SYK 💬
|
Fostamatinib Fostamatinib 💬
| Fostamatinib | 046 [4] 46, 49, 61, 66 💬
|
530 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
531 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
532 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
533 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
534 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
535 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
536 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
537 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
538 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
539 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFRSF13C [1] TNFRSF13C 💬
|
Ianalumab Ianalumab 💬
| Ianalumab | 035 [7] 35, 46, 49, 53, 61, 63, 95 💬
|
540 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF11 [1] TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
|
541 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B [1] TNFSF13B 💬
|
Atacicept Atacicept 💬
| Atacicept | 013 [4] 13, 46, 49, 66 💬
|
542 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B [1] TNFSF13B 💬
|
Belimumab Belimumab 💬
| Belimumab | 011 [13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
|
543 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B [1] TNFSF13B 💬
|
Tabalumab Tabalumab 💬
| Tabalumab | 046 [2] 46, 49 💬
|
544 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B [1] TNFSF13B 💬
|
Tibulizumab Tibulizumab 💬
| Tibulizumab | 053 [1] 53 💬
|
545 | Nicotinate and nicotinamide metabolism 💬 1 gene, 3 drugs (DrugBank) and 8 diseases |
CD38 [1] CD38 💬
|
Daratumumab Daratumumab 💬
| Daratumumab | 013 [5] 13, 28, 48, 49, 63 💬
|
546 | Nicotinate and nicotinamide metabolism 💬 1 gene, 3 drugs (DrugBank) and 8 diseases |
CD38 [1] CD38 💬
|
Isatuximab Isatuximab 💬
| Isatuximab | 028 [3] 28, 61, 283 💬
|
547 | Nicotinate and nicotinamide metabolism 💬 1 gene, 3 drugs (DrugBank) and 8 diseases |
CD38 [1] CD38 💬
|
Mezagitamab Mezagitamab 💬
| Mezagitamab | 063 [2] 63, 66 💬
|
548 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
CACNA1B [1] CACNA1B 💬
|
Cilnidipine Cilnidipine 💬
| Cilnidipine | 067 [1] 67 💬
|
549 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
CHRNA4 [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬
|
Nicotine Nicotine 💬
| Nicotine | 006 [3] 6 , 13, 84 💬
|
550 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
CHRNA4 [2] CHRNA4, CHRNB2 💬
|
Varenicline Varenicline 💬
| Varenicline | 006 [3] 6 , 18, 53 💬
|
551 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [1] GABRA1 💬
|
Etomidate Etomidate 💬
| Etomidate | 006 [1] 6 💬
|
552 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Alprazolam Alprazolam 💬
| Alprazolam | 008 [2] 8 , 75 💬
|
553 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Brexanolone Brexanolone 💬
| Brexanolone | 205 [1] 205 💬
|
554 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Clobazam Clobazam 💬
| Clobazam | 140 [2] 140, 144 💬
|
555 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Clonazepam Clonazepam 💬
| Clonazepam | 006 [1] 6 💬
|
556 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Delorazepam Delorazepam 💬
| Delorazepam | 006 [3] 6 , 46, 97 💬
|
557 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Diazepam Diazepam 💬
| Diazepam | 046 [3] 46, 155, 298 💬
|
558 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Eszopiclone Eszopiclone 💬
| Eszopiclone | 006 [3] 6 , 13, 46 💬
|
559 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Flumazenil Flumazenil 💬
| Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬
|
560 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Gaboxadol Gaboxadol 💬
| Gaboxadol | 201 [2] 201, 206 💬
|
561 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Ganaxolone Ganaxolone 💬
| Ganaxolone | 145 [4] 145, 152, 158, 206 💬
|
562 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Lorazepam Lorazepam 💬
| Lorazepam | 036 [1] 36 💬
|
563 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Midazolam Midazolam 💬
| Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
|
564 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Propofol Propofol 💬
| Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
|
565 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Zolpidem Zolpidem 💬
| Zolpidem | 005 [3] 5 , 6 , 46 💬
|
566 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬
|
Zopiclone Zopiclone 💬
| Zopiclone | 006 [1] 6 💬
|
567 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [20] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬
|
568 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Perampanel Perampanel 💬
| Perampanel | 002 [3] 2 , 6 , 144 💬
|
569 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬
|
Talampanel Talampanel 💬
| Talampanel | 002 [2] 2 , 6 💬
|
570 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Riluzole Riluzole 💬
| Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
|
571 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Acamprosate Acamprosate 💬
| Acamprosate | 006 [2] 6 , 206 💬
|
572 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 [4] 6 , 8 , 13, 127 💬
|
573 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Dextromethorphan Dextromethorphan 💬
| Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
|
574 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Esketamine Esketamine 💬
| Esketamine | 002 [3] 2 , 4 , 70 💬
|
575 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Ketamine Ketamine 💬
| Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
|
576 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Latrepirdine Latrepirdine 💬
| Latrepirdine | 008 [1] 8 💬
|
577 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
578 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬
|
Acetazolamide Acetazolamide 💬
| Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
|
579 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬
|
Dichlorphenamide Dichlorphenamide 💬
| Diclofenamide | 114 [1] 114 💬
|
580 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬
|
Dorzolamide Dorzolamide 💬
| Dorzolamide | 090 [1] 90 💬
|
581 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CA2 [2] CA2, CA4 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬
|
582 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
583 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
BCL2 [1] BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 [1] 28 💬
|
584 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CASR [1] CASR 💬
|
Cinacalcet Cinacalcet 💬
| Cinacalcet | 238 [1] 238 💬
|
585 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
586 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Rontalizumab Rontalizumab 💬
| Rontalizumab | 049 [1] 49 💬
|
587 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Sifalimumab Sifalimumab 💬
| Sifalimumab | 049 [1] 49 💬
|
588 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Anifrolumab Anifrolumab 💬
| Anifrolumab | 046 [3] 46, 49, 53 💬
|
589 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
590 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
591 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 [2] 25, 34 💬
|
592 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon beta-1a Interferon beta-1a 💬
| Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬
|
593 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon beta-1b Interferon beta-1b 💬
| Interferon beta-1b | 013 [1] 13 💬
|
594 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Peginterferon beta-1a Peginterferon beta-1a 💬
| Peginterferon beta-1a | 013 [1] 13 💬
|
595 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
596 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
597 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
598 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 [1] IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 [2] 46, 96 💬
|
599 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 [1] IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 [2] 28, 331 💬
|
600 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 [1] IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 [2] 41, 46 💬
|
601 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
602 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Abrocitinib Abrocitinib 💬
| Abrocitinib | 084 [1] 84 💬
|
603 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
604 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Filgotinib Filgotinib 💬
| Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬
|
605 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Itacitinib Itacitinib 💬
| Itacitinib | 046 [4] 46, 51, 97, 228 💬
|
606 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 [1] 46 💬
|
607 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 060 [3] 60, 65, 228 💬
|
608 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
|
609 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 [2] JAK1, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
610 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
611 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
612 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
613 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
PRKCD [1] PRKCD 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 [1] 97 💬
|
614 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
615 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
616 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
617 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
618 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
619 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
620 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
621 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
622 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
623 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
624 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TYK2 [1] TYK2 💬
|
Deucravacitinib Deucravacitinib 💬
| Deucravacitinib | 049 [3] 49, 96, 97 💬
|
625 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A [1] IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 [1] 51 💬
|
626 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A [2] IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 [4] 51, 106, 107, 266 💬
|
627 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
628 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
629 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
630 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 [1] IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 [2] 46, 96 💬
|
631 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 [1] IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 [2] 28, 331 💬
|
632 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 [1] IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 [2] 41, 46 💬
|
633 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 [2] IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
634 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R [1] IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬
|
635 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R [1] IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 [3] 11, 13, 86 💬
|
636 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
637 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬
|
Insulin detemir Insulin detemir 💬
| Insulin detemir | 299 [1] 299 💬
|
638 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬
|
Insulin glargine Insulin glargine 💬
| Insulin glargine | 299 [1] 299 💬
|
639 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬
|
Insulin human Insulin human 💬
| Insulin human | 096 [2] 96, 156 💬
|
640 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
LEPR [1] LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 [1] 265 💬
|
641 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
MAP3K5 [1] MAP3K5 💬
|
Selonsertib Selonsertib 💬
| Selonsertib | 086 [1] 86 💬
|
642 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
643 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
644 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
NFKB1 [1] NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬
|
645 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
646 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
647 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
648 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA [1] PPARA 💬
|
Bezafibrate Bezafibrate 💬
| Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬
|
649 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA [1] PPARA 💬
|
Elafibranor Elafibranor 💬
| Elafibranor | 093 [2] 93, 94 💬
|
650 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA [1] PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬
|
651 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA [1] PPARA 💬
|
Pemafibrate Pemafibrate 💬
| Pemafibrate | 093 [1] 93 💬
|
652 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬
|
Bocidelpar Bocidelpar 💬
| Bocidelpar | 113 [1] 113 💬
|
653 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬
|
Leriglitazone Leriglitazone 💬
| Leriglitazone | 020 [1] 20 💬
|
654 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
655 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬
|
656 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬
|
Seladelpar Seladelpar 💬
| Seladelpar | 093 [2] 93, 94 💬
|
657 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
658 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
RELA [1] RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 [1] 113 💬
|
659 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
RXRA [1] RXRA 💬
|
Acitretin Acitretin 💬
| Acitretin | 037 [1] 37 💬
|
660 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
RXRA [1] RXRA 💬
|
Alitretinoin Alitretinoin 💬
| Alitretinoin | 049 [1] 49 💬
|
661 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
RXRA [1] RXRA 💬
|
Bexarotene Bexarotene 💬
| Bexarotene | 013 [2] 13, 75 💬
|
662 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TGFB1 [1] TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
663 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
664 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
665 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
666 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
667 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
668 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
669 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
670 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
671 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
672 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
ALK [1] ALK 💬
|
Brigatinib Brigatinib 💬
| Brigatinib | 034 [1] 34 💬
|
673 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
ALK [1] ALK 💬
|
Crizotinib Crizotinib 💬
| Crizotinib | 034 [1] 34 💬
|
674 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
675 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF [3] BRAF, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
676 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
CASP9 [1] CASP9 💬
|
Rimiducid Rimiducid 💬
| Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬
|
677 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
CDK4 [2] CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 [1] 34 💬
|
678 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [1] EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 [2] 51, 86 💬
|
679 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [1] EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 [1] 94 💬
|
680 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [1] EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 [1] 75 💬
|
681 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
682 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
683 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
684 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
685 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
JAK3 [1] JAK3 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 [1] 46 💬
|
686 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
JAK3 [1] JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
687 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
688 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
689 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
690 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
691 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
692 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MET [1] MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
693 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
694 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
695 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
696 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
697 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [1] RARB 💬
|
Fenretinide Fenretinide 💬
| Fenretinide | 299 [1] 299 💬
|
698 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [1] RARB 💬
|
Isotretinoin Isotretinoin 💬
| Isotretinoin | 036 [4] 36, 39, 159, 160 💬
|
699 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [1] RARB 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬
|
700 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [1] RARB 💬
|
Vitamin A Vitamin A 💬
| Vitamin A | 013 [3] 13, 53, 90 💬
|
701 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬
|
Acitretin Acitretin 💬
| Acitretin | 037 [1] 37 💬
|
702 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬
|
Alitretinoin Alitretinoin 💬
| Alitretinoin | 049 [1] 49 💬
|
703 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RET [1] RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
704 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬
|
Bexarotene Bexarotene 💬
| Bexarotene | 013 [2] 13, 75 💬
|
705 | Notch signaling pathway 💬 7 genes, 3 drugs (DrugBank) and 4 diseases |
ADAM17 [1] ADAM17 💬
|
Apratastat Apratastat 💬
| Apratastat | 046 [1] 46 💬
|
706 | Notch signaling pathway 💬 7 genes, 3 drugs (DrugBank) and 4 diseases |
APH1A [4] APH1A, NCSTN, PSEN1, PSENEN 💬
|
Tarenflurbil Tarenflurbil 💬
| Tarenflurbil | 013 [1] 13 💬
|
707 | Notch signaling pathway 💬 7 genes, 3 drugs (DrugBank) and 4 diseases |
HDAC1 [2] HDAC1, HDAC2 💬
|
Vorinostat Vorinostat 💬
| Vorinostat | 075 [2] 75, 96 💬
|
708 | Nucleocytoplasmic transport 💬 2 genes, 2 drugs (DrugBank) and 2 diseases |
SMN2 [1] SMN2 💬
|
Risdiplam Risdiplam 💬
| Risdiplam | 003 [1] 3 💬
|
709 | Nucleocytoplasmic transport 💬 2 genes, 2 drugs (DrugBank) and 2 diseases |
XPO1 [1] XPO1 💬
|
Selinexor Selinexor 💬
| Selinexor | 028 [1] 28 💬
|
710 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
HPRT1 [1] HPRT1 💬
|
Mercaptopurine Mercaptopurine 💬
| Mercaptopurine | 065 [4] 65, 96, 97, 164 💬
|
711 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
HPRT1 [1] HPRT1 💬
|
Mercaptopurine Mercaptopurine 💬
| Mercaptopurine | 065 [4] 65, 96, 97, 164 💬
|
712 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
HPRT1 [1] HPRT1 💬
|
Tioguanine Tioguanine 💬
| Tioguanine | 013 [2] 13, 37 💬
|
713 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mizoribine Mizoribine 💬
| Mizoribine | 046 [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
|
714 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolate mofetil Mycophenolate mofetil 💬
| Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
715 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬
|
Mycophenolic acid Mycophenolic acid 💬
| Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
|
716 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬
|
Cladribine Cladribine 💬
| Cladribine | 011 [3] 11, 13, 94 💬
|
717 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬
|
Clofarabine Clofarabine 💬
| Clofarabine | 019 [5] 19, 20, 60, 234, 326 💬
|
718 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬
|
Fludarabine Fludarabine 💬
| Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
|
719 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM2 [1] RRM2 💬
|
Hydroxyurea Hydroxyurea 💬
| Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
|
720 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
TYMS [1] TYMS 💬
|
Tegafur Tegafur 💬
| Tegafur | 046 [1] 46 💬
|
721 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
XDH [1] XDH 💬
|
Allopurinol Allopurinol 💬
| Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬
|
722 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
XDH [1] XDH 💬
|
Febuxostat Febuxostat 💬
| Febuxostat | 002 [3] 2 , 6 , 13 💬
|