Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
3 Bile secretion 💬
 [1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
4 Collecting duct acid secretion 💬
 [1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
5 Dopaminergic synapse 💬
 [1] SCN1A 💬 Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
6 Dopaminergic synapse 💬
 [1] SCN1A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
7 Gastric acid secretion 💬
 [1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
8 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
9 Nitrogen metabolism 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
10 Pancreatic secretion 💬
 [1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
11 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
12 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
13 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬

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