Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 Lamotrigine 💬 Lamotrigine [6] 13, 34, 38, 113, 114, 144 💬
2 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 Mexiletine hydrochloride 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
3 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
4 Bile secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
5 Collecting duct acid secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
6 Dopaminergic synapse 💬
[1] SCN1A 💬 Lamotrigine 💬 Lamotrigine [6] 13, 34, 38, 113, 114, 144 💬
7 Dopaminergic synapse 💬
[1] SCN1A 💬 Mexiletine hydrochloride 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
8 Dopaminergic synapse 💬
[1] SCN1A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
9 Gastric acid secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
10 Nitrogen metabolism 💬
[13] CA, CA, CA, CA, CA, CA, CA, CA, CA, CA, CA, CA2, CA4 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
11 Pancreatic secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
12 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
13 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Lamotrigine 💬 Lamotrigine [6] 13, 34, 38, 113, 114, 144 💬
14 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Mexiletine hydrochloride 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
15 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬