Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
2 AGE-RAGE signaling pathway in diabetic complications 💬
 [2] VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
3 Bladder cancer 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
4 Bladder cancer 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
5 Calcium signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
6 Calcium signaling pathway 💬
 [2] VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
7 Chemical carcinogenesis - reactive oxygen species 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
8 Chemical carcinogenesis - reactive oxygen species 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
9 Chemical carcinogenesis - receptor activation 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
10 Chemical carcinogenesis - receptor activation 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
11 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [6] 63, 71, 85, 166, 222, 299 💬
12 Fluid shear stress and atherosclerosis 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
13 Fluid shear stress and atherosclerosis 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
14 Focal adhesion 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
15 Focal adhesion 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
16 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [6] 63, 71, 85, 166, 222, 299 💬
17 HIF-1 signaling pathway 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
18 HIF-1 signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
19 Human cytomegalovirus infection 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
20 Human cytomegalovirus infection 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
21 Human papillomavirus infection 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
22 Human papillomavirus infection 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
23 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
24 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
25 MAPK signaling pathway 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
26 MAPK signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
27 MicroRNAs in cancer 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
28 MicroRNAs in cancer 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
29 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [6] 63, 71, 85, 166, 222, 299 💬
30 Pancreatic cancer 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
31 Pancreatic cancer 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
32 Pathways in cancer 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
33 Pathways in cancer 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
34 PI3K-Akt signaling pathway 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
35 PI3K-Akt signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
36 Proteoglycans in cancer 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
37 Proteoglycans in cancer 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
38 Rap1 signaling pathway 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
39 Rap1 signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
40 Ras signaling pathway 💬
 [3] PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
41 Ras signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
42 Relaxin signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
43 Relaxin signaling pathway 💬
 [2] VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
44 Renal cell carcinoma 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
45 Renal cell carcinoma 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
46 Rheumatoid arthritis 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
47 Rheumatoid arthritis 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
48 VEGF signaling pathway 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
49 VEGF signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬

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