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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

AMPK signaling pathway 💬

[1] ADRA1A 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Calcium signaling pathway 💬

[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
ADRB3	beta-3 adrenergic receptor

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

cAMP signaling pathway 💬

[2] ADRB1, ADRB2 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

cGMP-PKG signaling pathway 💬

[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
ADRB3	beta-3 adrenergic receptor

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Chemical carcinogenesis - receptor activation 💬

[3] ADRB1, ADRB2, ADRB3 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Dilated cardiomyopathy 💬

[1] ADRB1 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Gap junction 💬

[1] ADRB1 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Hormone signaling 💬

[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
ADRB3	beta-3 adrenergic receptor

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Neuroactive ligand signaling 💬

[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Neuroactive ligand-receptor interaction 💬

[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
ADRB3	beta-3 adrenergic receptor

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Regulation of lipolysis in adipocytes 💬

[3] ADRB1, ADRB2, ADRB3 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Renin secretion 💬

[3] ADRB1, ADRB2, ADRB3 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Salivary secretion 💬

[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
ADRB3	beta-3 adrenergic receptor

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Thermogenesis 💬

[1] ADRB3 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;

Vascular smooth muscle contraction 💬

[3] ADRA1A, ADRA1B, ADRA1D 💬

Droxidopa 💬

Droxidopa

[5] 5 , 6 , 17, 169, 170 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
169	Menkes disease;Menkes syndrome;
170	Occipital horn syndrome;