Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
2 Alcoholism 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
3 Amphetamine addiction 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
4 Amphetamine addiction 💬
 [1] DRD1 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
5 Cadherin signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
6 Cadherin signaling 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
7 Calcium signaling pathway 💬
 [2] DRD1, DRD5 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
8 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
9 Cocaine addiction 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
10 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
11 Dopaminergic synapse 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
12 Dopaminergic synapse 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
13 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
14 GABAergic synapse 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
15 Gap junction 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
16 Hormone signaling 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
17 Morphine addiction 💬
 [1] DRD1 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
18 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
19 Morphine addiction 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
20 Neuroactive ligand signaling 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
21 Neuroactive ligand signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
22 Neuroactive ligand signaling 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
23 Neuroactive ligand-receptor interaction 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
24 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
25 Neuroactive ligand-receptor interaction 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
26 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
27 Nicotine addiction 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
28 Parkinson disease 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
29 Phenylalanine metabolism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
30 Rap1 signaling pathway 💬
 [1] DRD2 💬 Levodopa 💬 Levodopa [8]  5 ,  6 , 17, 90, 120, 140, 164, 201 💬
31 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
32 Retrograde endocannabinoid signaling 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
33 Serotonergic synapse 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
34 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
35 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
36 Taste transduction 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
37 Tryptophan metabolism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
38 Tyrosine metabolism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬

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