Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
2 Alcoholism 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
3 Amphetamine addiction 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
4 Amphetamine addiction 💬
 [1] DRD1 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
5 Calcium signaling pathway 💬
 [2] DRD1, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
6 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
7 Cocaine addiction 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
8 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
9 Dopaminergic synapse 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
10 Dopaminergic synapse 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
11 GABAergic synapse 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
12 GABAergic synapse 💬
 [16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
13 Gap junction 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
14 Hormone signaling 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
15 Morphine addiction 💬
 [1] DRD1 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
16 Morphine addiction 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
17 Morphine addiction 💬
 [16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
18 Neuroactive ligand signaling 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
19 Neuroactive ligand signaling 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
20 Neuroactive ligand signaling 💬
 [16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
21 Neuroactive ligand-receptor interaction 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
22 Neuroactive ligand-receptor interaction 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
23 Neuroactive ligand-receptor interaction 💬
 [16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
24 Nicotine addiction 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
25 Nicotine addiction 💬
 [16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
26 Parkinson disease 💬
 [2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
27 Phenylalanine metabolism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
28 Rap1 signaling pathway 💬
 [1] DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
29 Retrograde endocannabinoid signaling 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
30 Retrograde endocannabinoid signaling 💬
 [16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
31 Serotonergic synapse 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
32 Serotonergic synapse 💬
 [3] GABRB, GABRB, GABRB 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
33 Taste transduction 💬
 [1] GABRA 💬 Alogabat 💬 Alogabat [1] 201 💬
34 Taste transduction 💬
 [6] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
35 Tryptophan metabolism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬
36 Tyrosine metabolism 💬
 [1] DDC 💬 Carbidopa 💬 Carbidopa [5]  6 , 13, 17, 140, 201 💬

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