Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
2	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
3	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
4	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Noradrenaline 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
5	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Norepinephrine bitartrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
6	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Norepinephrine hydrochoride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
7	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium voltage-gated channel alpha subunit 5	Lidocaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine Lidocaine (JP18/USP/INN) Dentipatch (TN) Xylocaine (TN) LIDODERM ZTLIDO LIDOCAINE LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
8	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium voltage-gated channel alpha subunit 5	Lidocaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine hydrochloride Lidocaine hydrochloride (JAN/USP) Dalcaine (TN) Xylocaine (TN) AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HCI AND DEXTROSE LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE LIDOCAINE VISCOUS NA	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
9	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium voltage-gated channel alpha subunit 5	Lidocaine hydrochloride monohydrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate Lidocaine (TN) Zingo (TN) ZINGO 1% LIDOCAINE HCI 2% LIDOCAINE HCI LIDOCAINE HCI LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE LIDOCAINE VISCOUS NA	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
10	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium voltage-gated channel alpha subunit 5	Ropivacaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride (USP) Ropivacaine hydrochloride hydrate (JAN) Anapeine (TN) NAROPIN ROPIVACAINE HYDROCHLORIDE	Ropivacaine	[5] 22, 36, 46, 70, 97 💬 10. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
11	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium voltage-gated channel alpha subunit 5	Ropivacaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Ropivacaine Ropivacaine (INN) Naropin (TN)	Ropivacaine	[5] 22, 36, 46, 70, 97 💬 10. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
12	Alzheimer disease 💬	[1] PTGS2 💬 Alzheimer disease × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Alzheimer disease × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 12. Alzheimer disease × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
13	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A	Noradrenaline 💬 AMPK signaling pathway × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 13. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
14	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A	Norepinephrine bitartrate 💬 AMPK signaling pathway × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 13. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
15	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A	Norepinephrine hydrochoride 💬 AMPK signaling pathway × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 13. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
16	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A	Phenylephrine hydrochloride 💬 AMPK signaling pathway × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 16. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
17	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A	Phenylephrine 💬 AMPK signaling pathway × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 16. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
18	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A	Phenylephrine bitartrate 💬 AMPK signaling pathway × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 16. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
19	AMPK signaling pathway 💬	[1] HMGCR 💬 AMPK signaling pathway × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase	Atorvastatin calcium 💬 AMPK signaling pathway × Name Other Names Atorvastatin calcium Atorvastatin calcium (USP) Atorvastatin calcium hydrate (JP18) Atorvastatin calcium trihydrate Atorvaliq (TN) Lipitor (TN) ATORVALIQ LIPITOR ATORVASTATIN CALCIUM	Atorvastatin	[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬 19. AMPK signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
20	AMPK signaling pathway 💬	[1] HMGCR 💬 AMPK signaling pathway × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase	Atorvastatin 💬 AMPK signaling pathway × Name Other Names Atorvastatin Atorvastatin (INN) Lipitor (TN) Sortis (TN)	Atorvastatin	[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬 19. AMPK signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
21	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬 Arachidonic acid metabolism × Name Full Name PTGS1 prostaglandin-endoperoxide synthase 1 PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Arachidonic acid metabolism × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 21. Arachidonic acid metabolism × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
22	Bile secretion 💬	[1] HMGCR 💬 Bile secretion × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase	Atorvastatin calcium 💬 Bile secretion × Name Other Names Atorvastatin calcium Atorvastatin calcium (USP) Atorvastatin calcium hydrate (JP18) Atorvastatin calcium trihydrate Atorvaliq (TN) Lipitor (TN) ATORVALIQ LIPITOR ATORVASTATIN CALCIUM	Atorvastatin	[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬 22. Bile secretion × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
23	Bile secretion 💬	[1] HMGCR 💬 Bile secretion × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase	Atorvastatin 💬 Bile secretion × Name Other Names Atorvastatin Atorvastatin (INN) Lipitor (TN) Sortis (TN)	Atorvastatin	[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬 22. Bile secretion × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
24	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬 C-type lectin receptor signaling pathway × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 C-type lectin receptor signaling pathway × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 24. C-type lectin receptor signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
25	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Calcium signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Calcium signaling pathway × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 25. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
26	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Calcium signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Calcium signaling pathway × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 25. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
27	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Calcium signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Calcium signaling pathway × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 25. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
28	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Calcium signaling pathway × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 28. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
29	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Calcium signaling pathway × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 28. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
30	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Calcium signaling pathway × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 28. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
31	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Noradrenaline 💬 cAMP signaling pathway × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 31. cAMP signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
32	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Norepinephrine bitartrate 💬 cAMP signaling pathway × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 31. cAMP signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
33	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Norepinephrine hydrochoride 💬 cAMP signaling pathway × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 31. cAMP signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
34	cGMP-PKG signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 34. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
35	cGMP-PKG signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 cGMP-PKG signaling pathway × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 34. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
36	cGMP-PKG signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 cGMP-PKG signaling pathway × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 34. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
37	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 cGMP-PKG signaling pathway × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 37. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
38	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 cGMP-PKG signaling pathway × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 37. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
39	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 cGMP-PKG signaling pathway × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 37. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
40	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine 💬 cGMP-PKG signaling pathway × Name Other Names Dexmedetomidine Dexmedetomidine (USAN/INN) Dexdor (TN) Precedex (TN)	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 40. cGMP-PKG signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
41	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride (JAN/USP) Igalmi (TN) Precedex (TN) DEXMEDETOMIDINE IGALMI PRECEDEX DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 40. cGMP-PKG signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
42	Chemical carcinogenesis - DNA adducts 💬	[1] PTGS2 💬 Chemical carcinogenesis - DNA adducts × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Chemical carcinogenesis - DNA adducts × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 42. Chemical carcinogenesis - DNA adducts × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
43	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Chemical carcinogenesis - receptor activation × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 43. Chemical carcinogenesis - receptor activation × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
44	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Chemical carcinogenesis - receptor activation × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 43. Chemical carcinogenesis - receptor activation × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
45	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Chemical carcinogenesis - receptor activation × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 43. Chemical carcinogenesis - receptor activation × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
46	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 46. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
47	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 46. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
48	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 46. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
49	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 46. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
50	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 adrenoceptor beta 1	Noradrenaline 💬 Dilated cardiomyopathy × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 50. Dilated cardiomyopathy × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
51	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 adrenoceptor beta 1	Norepinephrine bitartrate 💬 Dilated cardiomyopathy × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 50. Dilated cardiomyopathy × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
52	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 adrenoceptor beta 1	Norepinephrine hydrochoride 💬 Dilated cardiomyopathy × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 50. Dilated cardiomyopathy × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
53	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium voltage-gated channel alpha subunit 1	Lidocaine 💬 Dopaminergic synapse × Name Other Names Lidocaine Lidocaine (JP18/USP/INN) Dentipatch (TN) Xylocaine (TN) LIDODERM ZTLIDO LIDOCAINE LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 53. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
54	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium voltage-gated channel alpha subunit 1	Lidocaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Lidocaine hydrochloride Lidocaine hydrochloride (JAN/USP) Dalcaine (TN) Xylocaine (TN) AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HCI AND DEXTROSE LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE LIDOCAINE VISCOUS NA	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 53. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
55	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium voltage-gated channel alpha subunit 1	Lidocaine hydrochloride monohydrate 💬 Dopaminergic synapse × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate Lidocaine (TN) Zingo (TN) ZINGO 1% LIDOCAINE HCI 2% LIDOCAINE HCI LIDOCAINE HCI LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE LIDOCAINE VISCOUS NA	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 53. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
56	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium voltage-gated channel alpha subunit 1	Ropivacaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride (USP) Ropivacaine hydrochloride hydrate (JAN) Anapeine (TN) NAROPIN ROPIVACAINE HYDROCHLORIDE	Ropivacaine	[5] 22, 36, 46, 70, 97 💬 56. Dopaminergic synapse × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
57	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium voltage-gated channel alpha subunit 1	Ropivacaine 💬 Dopaminergic synapse × Name Other Names Ropivacaine Ropivacaine (INN) Naropin (TN)	Ropivacaine	[5] 22, 36, 46, 70, 97 💬 56. Dopaminergic synapse × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
58	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 Efferocytosis × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 58. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
59	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 Efferocytosis × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 58. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
60	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 Efferocytosis × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 58. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
61	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 Efferocytosis × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 58. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
62	Efferocytosis 💬	[1] PTGS2 💬 Efferocytosis × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Efferocytosis × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 62. Efferocytosis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
63	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil hydrochloride 💬 Estrogen signaling pathway × Name Other Names Remifentanil hydrochloride Remifentanil hydrochloride (JAN/USAN) Ultiva (TN) ULTIVA REMIFENTANIL HYDROCHLORIDE	Remifentanil	[3]  6 , 22, 70 💬 63. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
64	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil 💬 Estrogen signaling pathway × Name Other Names Remifentanil Remifentanil (INN) Ultiva (TN)	Remifentanil	[3]  6 , 22, 70 💬 63. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
65	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil citrate 💬 Estrogen signaling pathway × Name Other Names Sufentanil citrate Sufentanil citrate (USP) Dsuvia (TN) Sufenta (TN) DSUVIA SUFENTANIL CITRATE	Sufentanil	[4] 11, 22, 70, 280 💬 65. Estrogen signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
66	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil 💬 Estrogen signaling pathway × Name Other Names Sufentanil Sufentanil (USAN/INN)	Sufentanil	[4] 11, 22, 70, 280 💬 65. Estrogen signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
67	GABAergic synapse 💬	[16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA GABRB GABRB GABRB GABRD gamma-aminobutyric acid type A receptor subunit delta GABRE gamma-aminobutyric acid type A receptor subunit epsilon GABRG GABRG GABRG GABRP gamma-aminobutyric acid type A receptor subunit pi GABRQ gamma-aminobutyric acid type A receptor subunit theta	Propofol 💬 GABAergic synapse × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 67. GABAergic synapse × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
68	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 adrenoceptor beta 1	Noradrenaline 💬 Gap junction × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 68. Gap junction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
69	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 adrenoceptor beta 1	Norepinephrine bitartrate 💬 Gap junction × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 68. Gap junction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
70	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 adrenoceptor beta 1	Norepinephrine hydrochoride 💬 Gap junction × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 68. Gap junction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
71	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 Hematopoietic cell lineage × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 71. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
72	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 Hematopoietic cell lineage × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 71. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
73	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 Hematopoietic cell lineage × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 71. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
74	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 Hematopoietic cell lineage × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 71. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
75	Hormone signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Hormone signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Hormone signaling × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 75. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
76	Hormone signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Hormone signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Hormone signaling × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 75. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
77	Hormone signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Hormone signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Hormone signaling × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 75. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
78	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Hormone signaling × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 78. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
79	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Hormone signaling × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 78. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
80	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Hormone signaling × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 78. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
81	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine 💬 Hormone signaling × Name Other Names Dexmedetomidine Dexmedetomidine (USAN/INN) Dexdor (TN) Precedex (TN)	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 81. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
82	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine hydrochloride 💬 Hormone signaling × Name Other Names Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride (JAN/USP) Igalmi (TN) Precedex (TN) DEXMEDETOMIDINE IGALMI PRECEDEX DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 81. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
83	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 Hormone signaling × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 83. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
84	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 Hormone signaling × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 83. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
85	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 Hormone signaling × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 83. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
86	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 Hormone signaling × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 83. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
87	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil hydrochloride 💬 Hormone signaling × Name Other Names Remifentanil hydrochloride Remifentanil hydrochloride (JAN/USAN) Ultiva (TN) ULTIVA REMIFENTANIL HYDROCHLORIDE	Remifentanil	[3]  6 , 22, 70 💬 87. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
88	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil 💬 Hormone signaling × Name Other Names Remifentanil Remifentanil (INN) Ultiva (TN)	Remifentanil	[3]  6 , 22, 70 💬 87. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
89	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil citrate 💬 Hormone signaling × Name Other Names Sufentanil citrate Sufentanil citrate (USP) Dsuvia (TN) Sufenta (TN) DSUVIA SUFENTANIL CITRATE	Sufentanil	[4] 11, 22, 70, 280 💬 89. Hormone signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
90	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil 💬 Hormone signaling × Name Other Names Sufentanil Sufentanil (USAN/INN)	Sufentanil	[4] 11, 22, 70, 280 💬 89. Hormone signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
91	Human cytomegalovirus infection 💬	[1] PTGS2 💬 Human cytomegalovirus infection × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Human cytomegalovirus infection × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 91. Human cytomegalovirus infection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
92	Human papillomavirus infection 💬	[1] PTGS2 💬 Human papillomavirus infection × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Human papillomavirus infection × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 92. Human papillomavirus infection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
93	IL-17 signaling pathway 💬	[1] PTGS2 💬 IL-17 signaling pathway × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 IL-17 signaling pathway × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 93. IL-17 signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
94	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 JAK-STAT signaling pathway × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 94. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
95	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 JAK-STAT signaling pathway × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 94. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
96	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 JAK-STAT signaling pathway × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 94. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 JAK-STAT signaling pathway × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 94. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
98	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 98. Kaposi sarcoma-associated herpesvirus infection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
99	Leishmaniasis 💬	[1] PTGS2 💬 Leishmaniasis × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Leishmaniasis × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 99. Leishmaniasis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
100	MicroRNAs in cancer 💬	[1] PTGS2 💬 MicroRNAs in cancer × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 MicroRNAs in cancer × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 100. MicroRNAs in cancer × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
101	Morphine addiction 💬	[16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA GABRB GABRB GABRB GABRD gamma-aminobutyric acid type A receptor subunit delta GABRE gamma-aminobutyric acid type A receptor subunit epsilon GABRG GABRG GABRG GABRP gamma-aminobutyric acid type A receptor subunit pi GABRQ gamma-aminobutyric acid type A receptor subunit theta	Propofol 💬 Morphine addiction × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 101. Morphine addiction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
102	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil hydrochloride 💬 Morphine addiction × Name Other Names Remifentanil hydrochloride Remifentanil hydrochloride (JAN/USAN) Ultiva (TN) ULTIVA REMIFENTANIL HYDROCHLORIDE	Remifentanil	[3]  6 , 22, 70 💬 102. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
103	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil 💬 Morphine addiction × Name Other Names Remifentanil Remifentanil (INN) Ultiva (TN)	Remifentanil	[3]  6 , 22, 70 💬 102. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
104	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil citrate 💬 Morphine addiction × Name Other Names Sufentanil citrate Sufentanil citrate (USP) Dsuvia (TN) Sufenta (TN) DSUVIA SUFENTANIL CITRATE	Sufentanil	[4] 11, 22, 70, 280 💬 104. Morphine addiction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
105	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil 💬 Morphine addiction × Name Other Names Sufentanil Sufentanil (USAN/INN)	Sufentanil	[4] 11, 22, 70, 280 💬 104. Morphine addiction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
106	Neuroactive ligand signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 106. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
107	Neuroactive ligand signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Neuroactive ligand signaling × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 106. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
108	Neuroactive ligand signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Neuroactive ligand signaling × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 106. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
109	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Noradrenaline 💬 Neuroactive ligand signaling × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 109. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
110	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Norepinephrine bitartrate 💬 Neuroactive ligand signaling × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 109. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
111	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2	Norepinephrine hydrochoride 💬 Neuroactive ligand signaling × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 109. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
112	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine 💬 Neuroactive ligand signaling × Name Other Names Dexmedetomidine Dexmedetomidine (USAN/INN) Dexdor (TN) Precedex (TN)	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 112. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
113	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride (JAN/USP) Igalmi (TN) Precedex (TN) DEXMEDETOMIDINE IGALMI PRECEDEX DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 112. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
114	Neuroactive ligand signaling 💬	[16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA GABRB GABRB GABRB GABRD gamma-aminobutyric acid type A receptor subunit delta GABRE gamma-aminobutyric acid type A receptor subunit epsilon GABRG GABRG GABRG GABRP gamma-aminobutyric acid type A receptor subunit pi GABRQ gamma-aminobutyric acid type A receptor subunit theta	Propofol 💬 Neuroactive ligand signaling × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 114. Neuroactive ligand signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
115	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Remifentanil hydrochloride Remifentanil hydrochloride (JAN/USAN) Ultiva (TN) ULTIVA REMIFENTANIL HYDROCHLORIDE	Remifentanil	[3]  6 , 22, 70 💬 115. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
116	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil 💬 Neuroactive ligand signaling × Name Other Names Remifentanil Remifentanil (INN) Ultiva (TN)	Remifentanil	[3]  6 , 22, 70 💬 115. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
117	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil citrate 💬 Neuroactive ligand signaling × Name Other Names Sufentanil citrate Sufentanil citrate (USP) Dsuvia (TN) Sufenta (TN) DSUVIA SUFENTANIL CITRATE	Sufentanil	[4] 11, 22, 70, 280 💬 117. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
118	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil 💬 Neuroactive ligand signaling × Name Other Names Sufentanil Sufentanil (USAN/INN)	Sufentanil	[4] 11, 22, 70, 280 💬 117. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
119	Neuroactive ligand-receptor interaction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 119. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
120	Neuroactive ligand-receptor interaction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Neuroactive ligand-receptor interaction × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 119. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
121	Neuroactive ligand-receptor interaction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 119. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
122	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Neuroactive ligand-receptor interaction × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 122. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
123	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 122. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
124	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Neuroactive ligand-receptor interaction × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 122. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
125	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexmedetomidine Dexmedetomidine (USAN/INN) Dexdor (TN) Precedex (TN)	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 125. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
126	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A adrenoceptor alpha 2A ADRA2B adrenoceptor alpha 2B ADRA2C adrenoceptor alpha 2C	Dexmedetomidine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride (JAN/USP) Igalmi (TN) Precedex (TN) DEXMEDETOMIDINE IGALMI PRECEDEX DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 125. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
127	Neuroactive ligand-receptor interaction 💬	[16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA GABRB GABRB GABRB GABRD gamma-aminobutyric acid type A receptor subunit delta GABRE gamma-aminobutyric acid type A receptor subunit epsilon GABRG GABRG GABRG GABRP gamma-aminobutyric acid type A receptor subunit pi GABRQ gamma-aminobutyric acid type A receptor subunit theta	Propofol 💬 Neuroactive ligand-receptor interaction × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 127. Neuroactive ligand-receptor interaction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
128	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Remifentanil hydrochloride Remifentanil hydrochloride (JAN/USAN) Ultiva (TN) ULTIVA REMIFENTANIL HYDROCHLORIDE	Remifentanil	[3]  6 , 22, 70 💬 128. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
129	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 opioid receptor mu 1	Remifentanil 💬 Neuroactive ligand-receptor interaction × Name Other Names Remifentanil Remifentanil (INN) Ultiva (TN)	Remifentanil	[3]  6 , 22, 70 💬 128. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis;
130	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil citrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Sufentanil citrate Sufentanil citrate (USP) Dsuvia (TN) Sufenta (TN) DSUVIA SUFENTANIL CITRATE	Sufentanil	[4] 11, 22, 70, 280 💬 130. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
131	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 opioid receptor mu 1	Sufentanil 💬 Neuroactive ligand-receptor interaction × Name Other Names Sufentanil Sufentanil (USAN/INN)	Sufentanil	[4] 11, 22, 70, 280 💬 130. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
132	NF-kappa B signaling pathway 💬	[1] PTGS2 💬 NF-kappa B signaling pathway × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 NF-kappa B signaling pathway × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 132. NF-kappa B signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
133	Nicotine addiction 💬	[16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA GABRB GABRB GABRB GABRD gamma-aminobutyric acid type A receptor subunit delta GABRE gamma-aminobutyric acid type A receptor subunit epsilon GABRG GABRG GABRG GABRP gamma-aminobutyric acid type A receptor subunit pi GABRQ gamma-aminobutyric acid type A receptor subunit theta	Propofol 💬 Nicotine addiction × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 133. Nicotine addiction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
134	Ovarian steroidogenesis 💬	[1] PTGS2 💬 Ovarian steroidogenesis × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Ovarian steroidogenesis × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 134. Ovarian steroidogenesis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
135	Oxytocin signaling pathway 💬	[1] PTGS2 💬 Oxytocin signaling pathway × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Oxytocin signaling pathway × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 135. Oxytocin signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
136	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 Pathways in cancer × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 136. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
137	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 Pathways in cancer × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 136. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
138	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 Pathways in cancer × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 136. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
139	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 Pathways in cancer × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 136. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
140	Pathways in cancer 💬	[1] PTGS2 💬 Pathways in cancer × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Pathways in cancer × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 140. Pathways in cancer × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
141	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 141. Pathways of neurodegeneration - multiple diseases × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
142	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin alfa 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin alfa Epoetin alfa (USAN/INN) Epoetin kappa (INN) Epoetin alfa (genetical recombination) (JP18) Epoetin kappa (genetical recombination) [Epoetin alfa biosimilar 1] (JAN) Epoetin alfa-epbx Epogen (TN) Epoetin alfa BS (TN) EPOGEN PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 142. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
143	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin epsilon 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin epsilon Epoetin epsilon (INN) Epoetin epsilon (genetical recombination) (JAN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 142. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
144	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin theta 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin theta Epoetin theta (INN) Biopoin (TN) Eporatio (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 142. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
145	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor	Epoetin zeta 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin zeta Epoetin zeta (INN) Retacrit (TN) Silapo (TN)	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬 142. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;:Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysial atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Neu:Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
146	Platelet activation 💬	[1] PTGS1 💬 Platelet activation × Name Full Name PTGS1 prostaglandin-endoperoxide synthase 1	Aspirin 💬 Platelet activation × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 146. Platelet activation × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
147	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Regulation of lipolysis in adipocytes × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 147. Regulation of lipolysis in adipocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
148	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Regulation of lipolysis in adipocytes × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 147. Regulation of lipolysis in adipocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
149	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Regulation of lipolysis in adipocytes × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 147. Regulation of lipolysis in adipocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
150	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGS1 prostaglandin-endoperoxide synthase 1 PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Regulation of lipolysis in adipocytes × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 150. Regulation of lipolysis in adipocytes × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
151	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Renin secretion × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 151. Renin secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
152	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Renin secretion × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 151. Renin secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
153	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Renin secretion × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 151. Renin secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
154	Retrograde endocannabinoid signaling 💬	[16] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA GABRB GABRB GABRB GABRD gamma-aminobutyric acid type A receptor subunit delta GABRE gamma-aminobutyric acid type A receptor subunit epsilon GABRG GABRG GABRG GABRP gamma-aminobutyric acid type A receptor subunit pi GABRQ gamma-aminobutyric acid type A receptor subunit theta	Propofol 💬 Retrograde endocannabinoid signaling × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 154. Retrograde endocannabinoid signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
155	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬 Retrograde endocannabinoid signaling × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Retrograde endocannabinoid signaling × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 155. Retrograde endocannabinoid signaling × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
156	Salivary secretion 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Salivary secretion × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Salivary secretion × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 156. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
157	Salivary secretion 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Salivary secretion × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Salivary secretion × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 156. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
158	Salivary secretion 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Salivary secretion × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Salivary secretion × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 156. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
159	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Salivary secretion × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 159. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
160	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Salivary secretion × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 159. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
161	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D ADRB1 adrenoceptor beta 1 ADRB2 adrenoceptor beta 2 ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Salivary secretion × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 159. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
162	Serotonergic synapse 💬	[3] GABRB, GABRB, GABRB 💬 Serotonergic synapse × Name Full Name GABRB GABRB GABRB	Propofol 💬 Serotonergic synapse × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 162. Serotonergic synapse × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
163	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬 Serotonergic synapse × Name Full Name PTGS1 prostaglandin-endoperoxide synthase 1 PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Serotonergic synapse × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 163. Serotonergic synapse × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
164	Small cell lung cancer 💬	[1] PTGS2 💬 Small cell lung cancer × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 Small cell lung cancer × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 164. Small cell lung cancer × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
165	Taste transduction 💬	[6] GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Taste transduction × Name Full Name GABRA GABRA GABRA GABRA GABRA GABRA	Propofol 💬 Taste transduction × Name Other Names Propofol Propofol (JAN/USP/INN) Diprivan (TN) DIPRIVAN PROPOFOL PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 165. Taste transduction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;  6  Parkinson disease;Disease Parkinson's; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
166	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium voltage-gated channel alpha subunit 2 SCN3A sodium voltage-gated channel alpha subunit 3 SCN9A sodium voltage-gated channel alpha subunit 9	Lidocaine 💬 Taste transduction × Name Other Names Lidocaine Lidocaine (JP18/USP/INN) Dentipatch (TN) Xylocaine (TN) LIDODERM ZTLIDO LIDOCAINE LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 166. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
167	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium voltage-gated channel alpha subunit 2 SCN3A sodium voltage-gated channel alpha subunit 3 SCN9A sodium voltage-gated channel alpha subunit 9	Lidocaine hydrochloride 💬 Taste transduction × Name Other Names Lidocaine hydrochloride Lidocaine hydrochloride (JAN/USP) Dalcaine (TN) Xylocaine (TN) AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HCI AND DEXTROSE LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE LIDOCAINE VISCOUS NA	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 166. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
168	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium voltage-gated channel alpha subunit 2 SCN3A sodium voltage-gated channel alpha subunit 3 SCN9A sodium voltage-gated channel alpha subunit 9	Lidocaine hydrochloride monohydrate 💬 Taste transduction × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate Lidocaine (TN) Zingo (TN) ZINGO 1% LIDOCAINE HCI 2% LIDOCAINE HCI LIDOCAINE HCI LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE LIDOCAINE VISCOUS NA	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 166. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
169	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium voltage-gated channel alpha subunit 2 SCN3A sodium voltage-gated channel alpha subunit 3 SCN9A sodium voltage-gated channel alpha subunit 9	Ropivacaine hydrochloride 💬 Taste transduction × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride (USP) Ropivacaine hydrochloride hydrate (JAN) Anapeine (TN) NAROPIN ROPIVACAINE HYDROCHLORIDE	Ropivacaine	[5] 22, 36, 46, 70, 97 💬 169. Taste transduction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
170	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium voltage-gated channel alpha subunit 2 SCN3A sodium voltage-gated channel alpha subunit 3 SCN9A sodium voltage-gated channel alpha subunit 9	Ropivacaine 💬 Taste transduction × Name Other Names Ropivacaine Ropivacaine (INN) Naropin (TN)	Ropivacaine	[5] 22, 36, 46, 70, 97 💬 169. Taste transduction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
171	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬 Terpenoid backbone biosynthesis × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase	Atorvastatin calcium 💬 Terpenoid backbone biosynthesis × Name Other Names Atorvastatin calcium Atorvastatin calcium (USP) Atorvastatin calcium hydrate (JP18) Atorvastatin calcium trihydrate Atorvaliq (TN) Lipitor (TN) ATORVALIQ LIPITOR ATORVASTATIN CALCIUM	Atorvastatin	[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬 171. Terpenoid backbone biosynthesis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
172	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬 Terpenoid backbone biosynthesis × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase	Atorvastatin 💬 Terpenoid backbone biosynthesis × Name Other Names Atorvastatin Atorvastatin (INN) Lipitor (TN) Sortis (TN)	Atorvastatin	[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬 171. Terpenoid backbone biosynthesis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
173	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 adrenoceptor beta 3	Noradrenaline 💬 Thermogenesis × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 173. Thermogenesis × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
174	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 adrenoceptor beta 3	Norepinephrine bitartrate 💬 Thermogenesis × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 173. Thermogenesis × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
175	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 adrenoceptor beta 3	Norepinephrine hydrochoride 💬 Thermogenesis × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 173. Thermogenesis × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
176	TNF signaling pathway 💬	[1] PTGS2 💬 TNF signaling pathway × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 TNF signaling pathway × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 176. TNF signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
177	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Noradrenaline 💬 Vascular smooth muscle contraction × Name Other Names Noradrenaline Noradrenaline (JP18) Norepinephrine (INN) Nor adrenalin (TN)	Norepinephrine	[2] 22, 296 💬 177. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
178	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Norepinephrine bitartrate 💬 Vascular smooth muscle contraction × Name Other Names Norepinephrine bitartrate Norepinephrine bitartrate (USP) Levophed (TN) LEVOPHED LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE NOREPINEPHR BITART	Norepinephrine	[2] 22, 296 💬 177. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
179	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Norepinephrine hydrochoride 💬 Vascular smooth muscle contraction × Name Other Names Norepinephrine hydrochoride Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol (TN)	Norepinephrine	[2] 22, 296 💬 177. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
180	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine hydrochloride 💬 Vascular smooth muscle contraction × Name Other Names Phenylephrine hydrochloride Phenylephrine hydrochloride (JP18/USP) Neo-synephrine (TN) BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE VAZCULEP	Phenylephrine	[1] 22 💬 180. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
181	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine 💬 Vascular smooth muscle contraction × Name Other Names Phenylephrine Phenylephrine (INN) Phenylephrine Minims (TN)	Phenylephrine	[1] 22 💬 180. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
182	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A adrenoceptor alpha 1A ADRA1B adrenoceptor alpha 1B ADRA1D adrenoceptor alpha 1D	Phenylephrine bitartrate 💬 Vascular smooth muscle contraction × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate (USP)	Phenylephrine	[1] 22 💬 180. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
183	VEGF signaling pathway 💬	[1] PTGS2 💬 VEGF signaling pathway × Name Full Name PTGS2 prostaglandin-endoperoxide synthase 2	Aspirin 💬 VEGF signaling pathway × Name Other Names Aspirin Aspirin (JP18/USP) Aspalon (JAN) Acetylsalicylic acid Easprin (TN) Durlaza (TN)	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬 183. VEGF signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 158 Tuberous sclerosis;Tuberous sclerosis complex;TSC; 210 Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome; 231 Alpha-1-antitrypsin deficiency;AATD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;

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