Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
2	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
3	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
4	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Noradrenaline 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
5	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Norepinephrine bitartrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
6	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Norepinephrine hydrochoride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
7	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
8	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
9	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride monohydrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
10	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 10. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
11	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 10. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
12	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Noradrenaline 💬 AMPK signaling pathway × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 12. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
13	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Norepinephrine bitartrate 💬 AMPK signaling pathway × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 12. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
14	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Norepinephrine hydrochoride 💬 AMPK signaling pathway × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 12. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
15	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Phenylephrine hydrochloride 💬 AMPK signaling pathway × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 15. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
16	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Phenylephrine 💬 AMPK signaling pathway × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 15. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
17	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Phenylephrine bitartrate 💬 AMPK signaling pathway × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 15. AMPK signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
18	AMPK signaling pathway 💬	[1] HMGCR 💬 AMPK signaling pathway × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	Atorvastatin calcium 💬 AMPK signaling pathway × Name Other Names Atorvastatin calcium Atorvastatin calcium hydrate Atorvastatin calcium trihydrate Atorvaliq Lipitor	Atorvastatin	[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 18. AMPK signaling pathway × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Austin syndrome;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
19	AMPK signaling pathway 💬	[1] HMGCR 💬 AMPK signaling pathway × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	Atorvastatin 💬 AMPK signaling pathway × Name Other Names Atorvastatin Lipitor Sortis	Atorvastatin	[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 18. AMPK signaling pathway × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Austin syndrome;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
20	Bile secretion 💬	[1] HMGCR 💬 Bile secretion × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	Atorvastatin calcium 💬 Bile secretion × Name Other Names Atorvastatin calcium Atorvastatin calcium hydrate Atorvastatin calcium trihydrate Atorvaliq Lipitor	Atorvastatin	[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 20. Bile secretion × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Austin syndrome;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
21	Bile secretion 💬	[1] HMGCR 💬 Bile secretion × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	Atorvastatin 💬 Bile secretion × Name Other Names Atorvastatin Lipitor Sortis	Atorvastatin	[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 20. Bile secretion × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Austin syndrome;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
22	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Cadherin signaling × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 22. Cadherin signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
23	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 Cadherin signaling × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 23. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
24	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 Cadherin signaling × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 23. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
25	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine 💬 Cadherin signaling × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 25. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
26	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride 💬 Cadherin signaling × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 25. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
27	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride monohydrate 💬 Cadherin signaling × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 25. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
28	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine hydrochloride 💬 Cadherin signaling × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 28. Cadherin signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
29	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine 💬 Cadherin signaling × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 28. Cadherin signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
30	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Calcium signaling pathway × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 30. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
31	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Calcium signaling pathway × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 30. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
32	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Calcium signaling pathway × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 30. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
33	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Calcium signaling pathway × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 33. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
34	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Calcium signaling pathway × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 33. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
35	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Calcium signaling pathway × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 33. Calcium signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
36	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Noradrenaline 💬 cAMP signaling pathway × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 36. cAMP signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
37	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Norepinephrine bitartrate 💬 cAMP signaling pathway × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 36. cAMP signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
38	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Norepinephrine hydrochoride 💬 cAMP signaling pathway × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 36. cAMP signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
39	cGMP-PKG signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 39. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
40	cGMP-PKG signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 cGMP-PKG signaling pathway × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 39. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
41	cGMP-PKG signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 cGMP-PKG signaling pathway × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 39. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
42	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 cGMP-PKG signaling pathway × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 42. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
43	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 cGMP-PKG signaling pathway × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 42. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
44	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 cGMP-PKG signaling pathway × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 42. cGMP-PKG signaling pathway × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
45	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 cGMP-PKG signaling pathway × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 45. cGMP-PKG signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
46	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 45. cGMP-PKG signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
47	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Chemical carcinogenesis - receptor activation × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 47. Chemical carcinogenesis - receptor activation × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
48	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Chemical carcinogenesis - receptor activation × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 47. Chemical carcinogenesis - receptor activation × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
49	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Chemical carcinogenesis - receptor activation × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 47. Chemical carcinogenesis - receptor activation × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
50	Complement and coagulation cascades 💬	[1] F8 💬 Complement and coagulation cascades × Name Full Name F8 coagulation factor VIII isoform a preproprotein	Desmopressin 💬 Complement and coagulation cascades × Name Other Names Desmopressin Desmopressin	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 50. Complement and coagulation cascades × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
51	Complement and coagulation cascades 💬	[1] F8 💬 Complement and coagulation cascades × Name Full Name F8 coagulation factor VIII isoform a preproprotein	Desmopressin acetate 💬 Complement and coagulation cascades × Name Other Names Desmopressin acetate Desmopressin acetate hydrate Desmopressin acetate trihydrate DDAVP Minirinmelt Stimate DESMODA	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 50. Complement and coagulation cascades × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
52	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 52. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
53	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 52. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
54	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 52. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
55	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 52. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
56	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 beta-1 adrenergic receptor	Noradrenaline 💬 Dilated cardiomyopathy × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 56. Dilated cardiomyopathy × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
57	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 beta-1 adrenergic receptor	Norepinephrine bitartrate 💬 Dilated cardiomyopathy × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 56. Dilated cardiomyopathy × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
58	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 beta-1 adrenergic receptor	Norepinephrine hydrochoride 💬 Dilated cardiomyopathy × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 56. Dilated cardiomyopathy × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
59	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Lidocaine 💬 Dopaminergic synapse × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 59. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
60	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Lidocaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 59. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
61	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Lidocaine hydrochloride monohydrate 💬 Dopaminergic synapse × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 59. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
62	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Ropivacaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 62. Dopaminergic synapse × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
63	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Ropivacaine 💬 Dopaminergic synapse × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 62. Dopaminergic synapse × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
64	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Efferocytosis × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 64. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
65	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Efferocytosis × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 64. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
66	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Efferocytosis × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 64. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
67	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Efferocytosis × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 64. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
68	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Estrogen signaling pathway × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 68. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
69	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Estrogen signaling pathway × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 68. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
70	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Estrogen signaling pathway × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 70. Estrogen signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
71	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Estrogen signaling pathway × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 70. Estrogen signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
72	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 GABAergic synapse × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 72. GABAergic synapse × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
73	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 GABAergic synapse × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 73. GABAergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
74	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 GABAergic synapse × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 73. GABAergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
75	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 beta-1 adrenergic receptor	Noradrenaline 💬 Gap junction × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 75. Gap junction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
76	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 beta-1 adrenergic receptor	Norepinephrine bitartrate 💬 Gap junction × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 75. Gap junction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
77	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 beta-1 adrenergic receptor	Norepinephrine hydrochoride 💬 Gap junction × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 75. Gap junction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
78	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Hematopoietic cell lineage × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 78. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
79	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Hematopoietic cell lineage × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 78. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
80	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Hematopoietic cell lineage × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 78. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
81	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Hematopoietic cell lineage × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 78. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
82	Hormone signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Hormone signaling × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 82. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
83	Hormone signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Hormone signaling × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 82. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
84	Hormone signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Hormone signaling × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 82. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
85	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Hormone signaling × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 85. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
86	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Hormone signaling × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 85. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
87	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Hormone signaling × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 85. Hormone signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
88	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 Hormone signaling × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 88. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
89	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 Hormone signaling × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 88. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
90	Hormone signaling 💬	[1] AVPR2 💬 Hormone signaling × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin 💬 Hormone signaling × Name Other Names Desmopressin Desmopressin	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 90. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
91	Hormone signaling 💬	[1] AVPR2 💬 Hormone signaling × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin acetate 💬 Hormone signaling × Name Other Names Desmopressin acetate Desmopressin acetate hydrate Desmopressin acetate trihydrate DDAVP Minirinmelt Stimate DESMODA	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 90. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
92	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Hormone signaling × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 92. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
93	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Hormone signaling × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 92. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
94	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Hormone signaling × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 92. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
95	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Hormone signaling × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 92. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
96	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Hormone signaling × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 96. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Hormone signaling × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 96. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
98	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Hormone signaling × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 98. Hormone signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
99	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Hormone signaling × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 98. Hormone signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
100	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Lidocaine 💬 IgSF CAM signaling × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 100. IgSF CAM signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
101	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Lidocaine hydrochloride 💬 IgSF CAM signaling × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 100. IgSF CAM signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
102	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Lidocaine hydrochloride monohydrate 💬 IgSF CAM signaling × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 100. IgSF CAM signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
103	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Ropivacaine hydrochloride 💬 IgSF CAM signaling × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 103. IgSF CAM signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
104	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Ropivacaine 💬 IgSF CAM signaling × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 103. IgSF CAM signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
105	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 JAK-STAT signaling pathway × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 105. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
106	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 JAK-STAT signaling pathway × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 105. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
107	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 JAK-STAT signaling pathway × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 105. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
108	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 JAK-STAT signaling pathway × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 105. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
109	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Morphine addiction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 109. Morphine addiction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
110	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 Morphine addiction × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 110. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
111	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 Morphine addiction × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 110. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
112	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Morphine addiction × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 112. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
113	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Morphine addiction × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 112. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
114	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Morphine addiction × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 114. Morphine addiction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
115	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Morphine addiction × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 114. Morphine addiction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
116	Neuroactive ligand signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 116. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
117	Neuroactive ligand signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Neuroactive ligand signaling × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 116. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
118	Neuroactive ligand signaling 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Neuroactive ligand signaling × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 116. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
119	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Noradrenaline 💬 Neuroactive ligand signaling × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 119. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
120	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Norepinephrine bitartrate 💬 Neuroactive ligand signaling × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 119. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
121	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Norepinephrine hydrochoride 💬 Neuroactive ligand signaling × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 119. Neuroactive ligand signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
122	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 Neuroactive ligand signaling × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 122. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
123	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 122. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
124	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Neuroactive ligand signaling × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 124. Neuroactive ligand signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
125	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 Neuroactive ligand signaling × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 125. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
126	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 Neuroactive ligand signaling × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 125. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
127	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 127. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
128	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Neuroactive ligand signaling × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 127. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
129	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Neuroactive ligand signaling × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 129. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
130	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Neuroactive ligand signaling × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 129. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
131	Neuroactive ligand-receptor interaction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 131. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
132	Neuroactive ligand-receptor interaction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Neuroactive ligand-receptor interaction × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 131. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
133	Neuroactive ligand-receptor interaction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 131. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
134	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Neuroactive ligand-receptor interaction × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 134. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
135	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 134. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
136	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Neuroactive ligand-receptor interaction × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 134. Neuroactive ligand-receptor interaction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
137	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 137. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
138	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 137. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
139	Neuroactive ligand-receptor interaction 💬	[1] AVPR2 💬 Neuroactive ligand-receptor interaction × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin 💬 Neuroactive ligand-receptor interaction × Name Other Names Desmopressin Desmopressin	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 139. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
140	Neuroactive ligand-receptor interaction 💬	[1] AVPR2 💬 Neuroactive ligand-receptor interaction × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin acetate 💬 Neuroactive ligand-receptor interaction × Name Other Names Desmopressin acetate Desmopressin acetate hydrate Desmopressin acetate trihydrate DDAVP Minirinmelt Stimate DESMODA	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 139. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
141	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Neuroactive ligand-receptor interaction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 141. Neuroactive ligand-receptor interaction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
142	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 Neuroactive ligand-receptor interaction × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 142. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
143	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 Neuroactive ligand-receptor interaction × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 142. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
144	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 144. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
145	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Neuroactive ligand-receptor interaction × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 144. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
146	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 146. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
147	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Neuroactive ligand-receptor interaction × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 146. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
148	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Nicotine addiction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 148. Nicotine addiction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
149	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 Nicotine addiction × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 149. Nicotine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
150	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 Nicotine addiction × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 149. Nicotine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
151	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Pathways in cancer × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 151. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
152	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Pathways in cancer × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 151. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
153	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Pathways in cancer × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 151. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
154	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Pathways in cancer × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 151. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
155	Phospholipase D signaling pathway 💬	[1] AVPR2 💬 Phospholipase D signaling pathway × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin 💬 Phospholipase D signaling pathway × Name Other Names Desmopressin Desmopressin	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 155. Phospholipase D signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
156	Phospholipase D signaling pathway 💬	[1] AVPR2 💬 Phospholipase D signaling pathway × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin acetate 💬 Phospholipase D signaling pathway × Name Other Names Desmopressin acetate Desmopressin acetate hydrate Desmopressin acetate trihydrate DDAVP Minirinmelt Stimate DESMODA	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 155. Phospholipase D signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
157	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 157. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
158	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 157. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
159	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 157. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
160	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 157. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
161	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Regulation of lipolysis in adipocytes × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 161. Regulation of lipolysis in adipocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
162	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Regulation of lipolysis in adipocytes × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 161. Regulation of lipolysis in adipocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
163	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Regulation of lipolysis in adipocytes × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 161. Regulation of lipolysis in adipocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
164	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Renin secretion × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 164. Renin secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
165	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Renin secretion × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 164. Renin secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
166	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Renin secretion × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 164. Renin secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
167	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Retrograde endocannabinoid signaling × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 167. Retrograde endocannabinoid signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
168	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam besylate 💬 Retrograde endocannabinoid signaling × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 168. Retrograde endocannabinoid signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
169	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Remimazolam 💬 Retrograde endocannabinoid signaling × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 168. Retrograde endocannabinoid signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
170	Salivary secretion 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Salivary secretion × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 170. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
171	Salivary secretion 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Salivary secretion × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 170. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
172	Salivary secretion 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Salivary secretion × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 170. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
173	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Salivary secretion × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 173. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
174	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Salivary secretion × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 173. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
175	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Salivary secretion × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 173. Salivary secretion × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
176	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Propofol 💬 Serotonergic synapse × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 176. Serotonergic synapse × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
177	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Remimazolam besylate 💬 Serotonergic synapse × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 177. Serotonergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
178	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Remimazolam 💬 Serotonergic synapse × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 177. Serotonergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
179	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Propofol 💬 Taste transduction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 179. Taste transduction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
180	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Remimazolam besylate 💬 Taste transduction × Name Other Names Remimazolam besylate Remimazolam besilate Anerem Byfavo	Remimazolam	[3]  6 , 22, 97 💬 180. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
181	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Remimazolam 💬 Taste transduction × Name Other Names Remimazolam Byfavo	Remimazolam	[3]  6 , 22, 97 💬 180. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
182	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Lidocaine 💬 Taste transduction × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 182. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
183	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Lidocaine hydrochloride 💬 Taste transduction × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 182. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
184	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Lidocaine hydrochloride monohydrate 💬 Taste transduction × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 182. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
185	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Ropivacaine hydrochloride 💬 Taste transduction × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 185. Taste transduction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
186	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Ropivacaine 💬 Taste transduction × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 185. Taste transduction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
187	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬 Terpenoid backbone biosynthesis × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	Atorvastatin calcium 💬 Terpenoid backbone biosynthesis × Name Other Names Atorvastatin calcium Atorvastatin calcium hydrate Atorvastatin calcium trihydrate Atorvaliq Lipitor	Atorvastatin	[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 187. Terpenoid backbone biosynthesis × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Austin syndrome;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
188	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬 Terpenoid backbone biosynthesis × Name Full Name HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	Atorvastatin 💬 Terpenoid backbone biosynthesis × Name Other Names Atorvastatin Lipitor Sortis	Atorvastatin	[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 187. Terpenoid backbone biosynthesis × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 58 Hypertrophic cardiomyopathy;HCM; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 160 Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Austin syndrome;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 265 Lipodystrophy; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 297 Alagille syndrome; 299 Cystic fibrosis;CF;
189	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 beta-3 adrenergic receptor	Noradrenaline 💬 Thermogenesis × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 189. Thermogenesis × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
190	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 beta-3 adrenergic receptor	Norepinephrine bitartrate 💬 Thermogenesis × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 189. Thermogenesis × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
191	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 beta-3 adrenergic receptor	Norepinephrine hydrochoride 💬 Thermogenesis × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 189. Thermogenesis × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
192	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Noradrenaline 💬 Vascular smooth muscle contraction × Name Other Names Noradrenaline Norepinephrine	Norepinephrine	[2] 22, 296 💬 192. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
193	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Norepinephrine bitartrate 💬 Vascular smooth muscle contraction × Name Other Names Norepinephrine bitartrate Levophed LEVOPHED(R) NOREPINEPHRINE BITARTRATE NOREPINEPHRINE NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE	Norepinephrine	[2] 22, 296 💬 192. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
194	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Norepinephrine hydrochoride 💬 Vascular smooth muscle contraction × Name Other Names Norepinephrine hydrochoride (-)-Noradrenaline hydrochloride Arterenol	Norepinephrine	[2] 22, 296 💬 192. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 296 Biliary atresia;
195	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine hydrochloride 💬 Vascular smooth muscle contraction × Name Other Names Phenylephrine hydrochloride Neo-synephrine BIORPHEN PHENYLEPHRINE HCI PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION	Phenylephrine	[1] 22 💬 195. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
196	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine 💬 Vascular smooth muscle contraction × Name Other Names Phenylephrine Phenylephrine Minims	Phenylephrine	[1] 22 💬 195. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
197	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Phenylephrine bitartrate 💬 Vascular smooth muscle contraction × Name Other Names Phenylephrine bitartrate Phenylephrine bitartrate	Phenylephrine	[1] 22 💬 195. Vascular smooth muscle contraction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis;
198	Vasopressin-regulated water reabsorption 💬	[1] AVPR2 💬 Vasopressin-regulated water reabsorption × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin 💬 Vasopressin-regulated water reabsorption × Name Other Names Desmopressin Desmopressin	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 198. Vasopressin-regulated water reabsorption × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;
199	Vasopressin-regulated water reabsorption 💬	[1] AVPR2 💬 Vasopressin-regulated water reabsorption × Name Full Name AVPR2 vasopressin V2 receptor isoform 1	Desmopressin acetate 💬 Vasopressin-regulated water reabsorption × Name Other Names Desmopressin acetate Desmopressin acetate hydrate Desmopressin acetate trihydrate DDAVP Minirinmelt Stimate DESMODA	Desmopressin	[8]  6 , 22, 64, 72, 75, 223, 225, 288 💬 198. Vasopressin-regulated water reabsorption × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 75 Cushing disease;Cushing syndrome; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 225 Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus; 288 Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Acquired factor XIII deficiency;Autoimmune acquired factor XIII (F13) deficiency;Acquired factor VIII deficiency;Autoimmune acquired factor VIII (F8) deficiency;Acquired hemophilia A;VWF deficiency;Acquired von Willebrand syndrome;Acquired von Willebrand Disease;AVWS;AVWD;Acquired factor V deficiency;Autoimmune acquired factor V (F5) deficiency;Acquired factor X deficiency;

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