Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Alcoholic liver disease 💬 43 genes, 56 drugs (DrugBank) and 98 diseases |
C5 [1] C5 💬Alcoholic liver disease
|
Eculizumab Eculizumab 💬Alcoholic liver disease
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬1. Alcoholic liver disease
|
||||||||||||||||||||||||||||||
| 2 | Cell adhesion molecule (CAM) interaction 💬 41 genes, 32 drugs (DrugBank) and 40 diseases |
ITGAL [1] ITGAL 💬Cell adhesion molecule (CAM) interaction
|
Efalizumab Efalizumab 💬Cell adhesion molecule (CAM) interaction
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬2. Cell adhesion molecule (CAM) interaction
|
||||||||||||||||||||||||||||||
| 3 | Complement and coagulation cascades 💬 21 genes, 46 drugs (DrugBank) and 60 diseases |
C5 [1] C5 💬Complement and coagulation cascades
|
Eculizumab Eculizumab 💬Complement and coagulation cascades
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬3. Complement and coagulation cascades
|
||||||||||||||||||||||||||||||
| 4 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
C5 [1] C5 💬Coronavirus disease
|
Eculizumab Eculizumab 💬Coronavirus disease
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬4. Coronavirus disease
|
||||||||||||||||||||||||||||||
| 5 | Epstein-Barr virus infection 💬 67 genes, 97 drugs (DrugBank) and 83 diseases |
ITGAL [1] ITGAL 💬Epstein-Barr virus infection
|
Efalizumab Efalizumab 💬Epstein-Barr virus infection
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬5. Epstein-Barr virus infection
|
||||||||||||||||||||||||||||||
| 6 | Herpes simplex virus 1 infection 💬 71 genes, 85 drugs (DrugBank) and 110 diseases |
C5 [1] C5 💬Herpes simplex virus 1 infection
|
Eculizumab Eculizumab 💬Herpes simplex virus 1 infection
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬6. Herpes simplex virus 1 infection
|
||||||||||||||||||||||||||||||
| 7 | Human T-cell leukemia virus 1 infection 💬 61 genes, 80 drugs (DrugBank) and 105 diseases |
ITGAL [1] ITGAL 💬Human T-cell leukemia virus 1 infection
|
Efalizumab Efalizumab 💬Human T-cell leukemia virus 1 infection
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬7. Human T-cell leukemia virus 1 infection
|
||||||||||||||||||||||||||||||
| 8 | IgSF CAM signaling 💬 45 genes, 68 drugs (DrugBank) and 91 diseases |
ITGAL [1] ITGAL 💬IgSF CAM signaling
|
Efalizumab Efalizumab 💬IgSF CAM signaling
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬8. IgSF CAM signaling
|
||||||||||||||||||||||||||||||
| 9 | Integrin signaling 💬 28 genes, 48 drugs (DrugBank) and 77 diseases |
ITGAL [1] ITGAL 💬Integrin signaling
|
Efalizumab Efalizumab 💬Integrin signaling
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬9. Integrin signaling
|
||||||||||||||||||||||||||||||
| 10 | Leukocyte transendothelial migration 💬 19 genes, 23 drugs (DrugBank) and 37 diseases |
ITGAL [1] ITGAL 💬Leukocyte transendothelial migration
|
Efalizumab Efalizumab 💬Leukocyte transendothelial migration
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬10. Leukocyte transendothelial migration
|
||||||||||||||||||||||||||||||
| 11 | Malaria 💬 17 genes, 31 drugs (DrugBank) and 69 diseases |
ITGAL [1] ITGAL 💬Malaria
|
Efalizumab Efalizumab 💬Malaria
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬11. Malaria
|
||||||||||||||||||||||||||||||
| 12 | Natural killer cell mediated cytotoxicity 💬 45 genes, 49 drugs (DrugBank) and 91 diseases |
ITGAL [1] ITGAL 💬Natural killer cell mediated cytotoxicity
|
Efalizumab Efalizumab 💬Natural killer cell mediated cytotoxicity
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬12. Natural killer cell mediated cytotoxicity
|
||||||||||||||||||||||||||||||
| 13 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
C5 [1] C5 💬Neuroactive ligand-receptor interaction
|
Eculizumab Eculizumab 💬Neuroactive ligand-receptor interaction
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬13. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||
| 14 | Neutrophil extracellular trap formation 💬 37 genes, 45 drugs (DrugBank) and 78 diseases |
C5 [1] C5 💬Neutrophil extracellular trap formation
|
Eculizumab Eculizumab 💬Neutrophil extracellular trap formation
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬14. Neutrophil extracellular trap formation
|
||||||||||||||||||||||||||||||
| 15 | Neutrophil extracellular trap formation 💬 37 genes, 45 drugs (DrugBank) and 78 diseases |
ITGAL [1] ITGAL 💬Neutrophil extracellular trap formation
|
Efalizumab Efalizumab 💬Neutrophil extracellular trap formation
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬15. Neutrophil extracellular trap formation
|
||||||||||||||||||||||||||||||
| 16 | Pertussis 💬 23 genes, 48 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬Pertussis
|
Eculizumab Eculizumab 💬Pertussis
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬16. Pertussis
|
||||||||||||||||||||||||||||||
| 17 | Prion disease 💬 41 genes, 77 drugs (DrugBank) and 121 diseases |
C5 [1] C5 💬Prion disease
|
Eculizumab Eculizumab 💬Prion disease
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬17. Prion disease
|
||||||||||||||||||||||||||||||
| 18 | Rap1 signaling pathway 💬 47 genes, 115 drugs (DrugBank) and 101 diseases |
ITGAL [1] ITGAL 💬Rap1 signaling pathway
|
Efalizumab Efalizumab 💬Rap1 signaling pathway
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬18. Rap1 signaling pathway
|
||||||||||||||||||||||||||||||
| 19 | Regulation of actin cytoskeleton 💬 37 genes, 82 drugs (DrugBank) and 79 diseases |
C5 [1] C5 💬Regulation of actin cytoskeleton
|
Eculizumab Eculizumab 💬Regulation of actin cytoskeleton
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬19. Regulation of actin cytoskeleton
|
||||||||||||||||||||||||||||||
| 20 | Regulation of actin cytoskeleton 💬 37 genes, 82 drugs (DrugBank) and 79 diseases |
ITGAL [1] ITGAL 💬Regulation of actin cytoskeleton
|
Efalizumab Efalizumab 💬Regulation of actin cytoskeleton
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬20. Regulation of actin cytoskeleton
|
||||||||||||||||||||||||||||||
| 21 | Rheumatoid arthritis 💬 39 genes, 59 drugs (DrugBank) and 85 diseases |
ITGAL [1] ITGAL 💬Rheumatoid arthritis
|
Efalizumab Efalizumab 💬Rheumatoid arthritis
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬21. Rheumatoid arthritis
|
||||||||||||||||||||||||||||||
| 22 | Staphylococcus aureus infection 💬 29 genes, 26 drugs (DrugBank) and 42 diseases |
C5 [1] C5 💬Staphylococcus aureus infection
|
Eculizumab Eculizumab 💬Staphylococcus aureus infection
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬22. Staphylococcus aureus infection
|
||||||||||||||||||||||||||||||
| 23 | Staphylococcus aureus infection 💬 29 genes, 26 drugs (DrugBank) and 42 diseases |
ITGAL [1] ITGAL 💬Staphylococcus aureus infection
|
Efalizumab Efalizumab 💬Staphylococcus aureus infection
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬23. Staphylococcus aureus infection
|
||||||||||||||||||||||||||||||
| 24 | Systemic lupus erythematosus 💬 30 genes, 49 drugs (DrugBank) and 90 diseases |
C5 [1] C5 💬Systemic lupus erythematosus
|
Eculizumab Eculizumab 💬Systemic lupus erythematosus
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 223 💬24. Systemic lupus erythematosus
|
||||||||||||||||||||||||||||||
| 25 | Viral myocarditis 💬 34 genes, 25 drugs (DrugBank) and 49 diseases |
ITGAL [1] ITGAL 💬Viral myocarditis
|
Efalizumab Efalizumab 💬Viral myocarditis
| Efalizumab | 011 [10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬25. Viral myocarditis
|
Alcoholic liver disease
43 genes, 56 drugs (DrugBank) and 98 diseases
Cell adhesion molecule (CAM) interaction
41 genes, 32 drugs (DrugBank) and 40 diseases
Complement and coagulation cascades
21 genes, 46 drugs (DrugBank) and 60 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Epstein-Barr virus infection
67 genes, 97 drugs (DrugBank) and 83 diseases
Herpes simplex virus 1 infection
71 genes, 85 drugs (DrugBank) and 110 diseases
Human T-cell leukemia virus 1 infection
61 genes, 80 drugs (DrugBank) and 105 diseases
IgSF CAM signaling
45 genes, 68 drugs (DrugBank) and 91 diseases
Integrin signaling
28 genes, 48 drugs (DrugBank) and 77 diseases
Leukocyte transendothelial migration
19 genes, 23 drugs (DrugBank) and 37 diseases
Malaria
17 genes, 31 drugs (DrugBank) and 69 diseases
Natural killer cell mediated cytotoxicity
45 genes, 49 drugs (DrugBank) and 91 diseases
Neuroactive ligand-receptor interaction
156 genes, 371 drugs (DrugBank) and 171 diseases
Neutrophil extracellular trap formation
37 genes, 45 drugs (DrugBank) and 78 diseases
Pertussis
23 genes, 48 drugs (DrugBank) and 77 diseases
Prion disease
41 genes, 77 drugs (DrugBank) and 121 diseases
Rap1 signaling pathway
47 genes, 115 drugs (DrugBank) and 101 diseases
Regulation of actin cytoskeleton
37 genes, 82 drugs (DrugBank) and 79 diseases
Rheumatoid arthritis
39 genes, 59 drugs (DrugBank) and 85 diseases
Staphylococcus aureus infection
29 genes, 26 drugs (DrugBank) and 42 diseases
Systemic lupus erythematosus
30 genes, 49 drugs (DrugBank) and 90 diseases
Viral myocarditis
34 genes, 25 drugs (DrugBank) and 49 diseases
