Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||
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1 | Alcoholic liver disease 💬 42 genes, 54 drugs (DrugBank) and 91 diseases |
C5 [1] C5 💬Alcoholic liver disease
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Eculizumab Eculizumab 💬Alcoholic liver disease
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬1. Alcoholic liver disease
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2 | Cell adhesion molecules 💬 43 genes, 34 drugs (DrugBank) and 43 diseases |
ITGAL [1] ITGAL 💬Cell adhesion molecules
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Efalizumab Efalizumab 💬Cell adhesion molecules
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬2. Cell adhesion molecules
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3 | Complement and coagulation cascades 💬 22 genes, 45 drugs (DrugBank) and 52 diseases |
C5 [1] C5 💬Complement and coagulation cascades
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Eculizumab Eculizumab 💬Complement and coagulation cascades
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬3. Complement and coagulation cascades
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4 | Coronavirus disease - COVID-19 💬 54 genes, 108 drugs (DrugBank) and 105 diseases |
C5 [1] C5 💬Coronavirus disease - COVID-19
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Eculizumab Eculizumab 💬Coronavirus disease - COVID-19
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬4. Coronavirus disease - COVID-19
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5 | Epstein-Barr virus infection 💬 67 genes, 90 drugs (DrugBank) and 82 diseases |
ITGAL [1] ITGAL 💬Epstein-Barr virus infection
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Efalizumab Efalizumab 💬Epstein-Barr virus infection
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬5. Epstein-Barr virus infection
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6 | Herpes simplex virus 1 infection 💬 70 genes, 80 drugs (DrugBank) and 107 diseases |
C5 [1] C5 💬Herpes simplex virus 1 infection
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Eculizumab Eculizumab 💬Herpes simplex virus 1 infection
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬6. Herpes simplex virus 1 infection
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7 | Human T-cell leukemia virus 1 infection 💬 59 genes, 74 drugs (DrugBank) and 96 diseases |
ITGAL [1] ITGAL 💬Human T-cell leukemia virus 1 infection
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Efalizumab Efalizumab 💬Human T-cell leukemia virus 1 infection
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬7. Human T-cell leukemia virus 1 infection
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8 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGAL [1] ITGAL 💬Leukocyte transendothelial migration
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Efalizumab Efalizumab 💬Leukocyte transendothelial migration
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬8. Leukocyte transendothelial migration
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9 | Malaria 💬 16 genes, 32 drugs (DrugBank) and 71 diseases |
ITGAL [1] ITGAL 💬Malaria
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Efalizumab Efalizumab 💬Malaria
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬9. Malaria
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10 | Natural killer cell mediated cytotoxicity 💬 44 genes, 50 drugs (DrugBank) and 86 diseases |
ITGAL [1] ITGAL 💬Natural killer cell mediated cytotoxicity
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Efalizumab Efalizumab 💬Natural killer cell mediated cytotoxicity
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬10. Natural killer cell mediated cytotoxicity
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11 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
C5 [1] C5 💬Neuroactive ligand-receptor interaction
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Eculizumab Eculizumab 💬Neuroactive ligand-receptor interaction
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬11. Neuroactive ligand-receptor interaction
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12 | Neutrophil extracellular trap formation 💬 36 genes, 46 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬Neutrophil extracellular trap formation
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Eculizumab Eculizumab 💬Neutrophil extracellular trap formation
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬12. Neutrophil extracellular trap formation
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13 | Neutrophil extracellular trap formation 💬 36 genes, 46 drugs (DrugBank) and 77 diseases |
ITGAL [1] ITGAL 💬Neutrophil extracellular trap formation
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Efalizumab Efalizumab 💬Neutrophil extracellular trap formation
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬13. Neutrophil extracellular trap formation
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14 | Pertussis 💬 22 genes, 46 drugs (DrugBank) and 73 diseases |
C5 [1] C5 💬Pertussis
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Eculizumab Eculizumab 💬Pertussis
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬14. Pertussis
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15 | Prion disease 💬 41 genes, 74 drugs (DrugBank) and 114 diseases |
C5 [1] C5 💬Prion disease
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Eculizumab Eculizumab 💬Prion disease
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬15. Prion disease
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16 | Rap1 signaling pathway 💬 45 genes, 113 drugs (DrugBank) and 98 diseases |
ITGAL [1] ITGAL 💬Rap1 signaling pathway
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Efalizumab Efalizumab 💬Rap1 signaling pathway
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬16. Rap1 signaling pathway
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17 | Regulation of actin cytoskeleton 💬 35 genes, 82 drugs (DrugBank) and 81 diseases |
C5 [1] C5 💬Regulation of actin cytoskeleton
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Eculizumab Eculizumab 💬Regulation of actin cytoskeleton
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬17. Regulation of actin cytoskeleton
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18 | Regulation of actin cytoskeleton 💬 35 genes, 82 drugs (DrugBank) and 81 diseases |
ITGAL [1] ITGAL 💬Regulation of actin cytoskeleton
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Efalizumab Efalizumab 💬Regulation of actin cytoskeleton
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬18. Regulation of actin cytoskeleton
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19 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
ITGAL [1] ITGAL 💬Rheumatoid arthritis
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Efalizumab Efalizumab 💬Rheumatoid arthritis
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬19. Rheumatoid arthritis
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20 | Staphylococcus aureus infection 💬 28 genes, 26 drugs (DrugBank) and 46 diseases |
C5 [1] C5 💬Staphylococcus aureus infection
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Eculizumab Eculizumab 💬Staphylococcus aureus infection
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬20. Staphylococcus aureus infection
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21 | Staphylococcus aureus infection 💬 28 genes, 26 drugs (DrugBank) and 46 diseases |
ITGAL [1] ITGAL 💬Staphylococcus aureus infection
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Efalizumab Efalizumab 💬Staphylococcus aureus infection
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬21. Staphylococcus aureus infection
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22 | Systemic lupus erythematosus 💬 30 genes, 49 drugs (DrugBank) and 83 diseases |
C5 [1] C5 💬Systemic lupus erythematosus
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Eculizumab Eculizumab 💬Systemic lupus erythematosus
| Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 221, 222 💬22. Systemic lupus erythematosus
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23 | Viral myocarditis 💬 34 genes, 27 drugs (DrugBank) and 52 diseases |
ITGAL [1] ITGAL 💬Viral myocarditis
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Efalizumab Efalizumab 💬Viral myocarditis
| Efalizumab | 011 [9] 11, 13, 37, 46, 53, 61, 95, 96, 221 💬23. Viral myocarditis
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Alcoholic liver disease
42 genes, 54 drugs (DrugBank) and 91 diseases
Cell adhesion molecules
43 genes, 34 drugs (DrugBank) and 43 diseases
Complement and coagulation cascades
22 genes, 45 drugs (DrugBank) and 52 diseases
Coronavirus disease - COVID-19
54 genes, 108 drugs (DrugBank) and 105 diseases
Epstein-Barr virus infection
67 genes, 90 drugs (DrugBank) and 82 diseases
Herpes simplex virus 1 infection
70 genes, 80 drugs (DrugBank) and 107 diseases
Human T-cell leukemia virus 1 infection
59 genes, 74 drugs (DrugBank) and 96 diseases
Leukocyte transendothelial migration
18 genes, 23 drugs (DrugBank) and 44 diseases
Malaria
16 genes, 32 drugs (DrugBank) and 71 diseases
Natural killer cell mediated cytotoxicity
44 genes, 50 drugs (DrugBank) and 86 diseases
Neuroactive ligand-receptor interaction
158 genes, 364 drugs (DrugBank) and 173 diseases
Neutrophil extracellular trap formation
36 genes, 46 drugs (DrugBank) and 77 diseases
Pertussis
22 genes, 46 drugs (DrugBank) and 73 diseases
Prion disease
41 genes, 74 drugs (DrugBank) and 114 diseases
Rap1 signaling pathway
45 genes, 113 drugs (DrugBank) and 98 diseases
Regulation of actin cytoskeleton
35 genes, 82 drugs (DrugBank) and 81 diseases
Rheumatoid arthritis
38 genes, 59 drugs (DrugBank) and 87 diseases
Staphylococcus aureus infection
28 genes, 26 drugs (DrugBank) and 46 diseases
Systemic lupus erythematosus
30 genes, 49 drugs (DrugBank) and 83 diseases
Viral myocarditis
34 genes, 27 drugs (DrugBank) and 52 diseases