Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||
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1 | African trypanosomiasis 💬 10 genes, 24 drugs (DrugBank) and 62 diseases |
IL1B [1] IL1B 💬African trypanosomiasis
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Canakinumab Canakinumab 💬African trypanosomiasis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬1. African trypanosomiasis
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2 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 55 drugs (DrugBank) and 96 diseases |
IL1B [1] IL1B 💬AGE-RAGE signaling pathway in diabetic complications
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Canakinumab Canakinumab 💬AGE-RAGE signaling pathway in diabetic complications
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬2. AGE-RAGE signaling pathway in diabetic complications
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3 | Alcoholic liver disease 💬 42 genes, 54 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬Alcoholic liver disease
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Canakinumab Canakinumab 💬Alcoholic liver disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬3. Alcoholic liver disease
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4 | Alzheimer disease 💬 59 genes, 132 drugs (DrugBank) and 129 diseases |
IL1B [1] IL1B 💬Alzheimer disease
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Canakinumab Canakinumab 💬Alzheimer disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬4. Alzheimer disease
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5 | Amoebiasis 💬 20 genes, 32 drugs (DrugBank) and 71 diseases |
IL1B [1] IL1B 💬Amoebiasis
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Canakinumab Canakinumab 💬Amoebiasis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬5. Amoebiasis
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6 | C-type lectin receptor signaling pathway 💬 27 genes, 66 drugs (DrugBank) and 102 diseases |
IL1B [1] IL1B 💬C-type lectin receptor signaling pathway
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Canakinumab Canakinumab 💬C-type lectin receptor signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬6. C-type lectin receptor signaling pathway
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7 | Chagas disease 💬 31 genes, 56 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬Chagas disease
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Canakinumab Canakinumab 💬Chagas disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬7. Chagas disease
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8 | Coronavirus disease - COVID-19 💬 54 genes, 108 drugs (DrugBank) and 105 diseases |
IL1B [1] IL1B 💬Coronavirus disease - COVID-19
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Canakinumab Canakinumab 💬Coronavirus disease - COVID-19
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬8. Coronavirus disease - COVID-19
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9 | Cytokine-cytokine receptor interaction 💬 89 genes, 142 drugs (DrugBank) and 110 diseases |
IL1B [1] IL1B 💬Cytokine-cytokine receptor interaction
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Canakinumab Canakinumab 💬Cytokine-cytokine receptor interaction
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬9. Cytokine-cytokine receptor interaction
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10 | Cytosolic DNA-sensing pathway 💬 20 genes, 16 drugs (DrugBank) and 31 diseases |
IL1B [1] IL1B 💬Cytosolic DNA-sensing pathway
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Canakinumab Canakinumab 💬Cytosolic DNA-sensing pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬10. Cytosolic DNA-sensing pathway
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11 | Fluid shear stress and atherosclerosis 💬 34 genes, 59 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬Fluid shear stress and atherosclerosis
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Canakinumab Canakinumab 💬Fluid shear stress and atherosclerosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬11. Fluid shear stress and atherosclerosis
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12 | Graft-versus-host disease 💬 28 genes, 25 drugs (DrugBank) and 64 diseases |
IL1B [1] IL1B 💬Graft-versus-host disease
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Canakinumab Canakinumab 💬Graft-versus-host disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬12. Graft-versus-host disease
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13 | Hematopoietic cell lineage 💬 53 genes, 95 drugs (DrugBank) and 101 diseases |
IL1B [1] IL1B 💬Hematopoietic cell lineage
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Canakinumab Canakinumab 💬Hematopoietic cell lineage
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬13. Hematopoietic cell lineage
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14 | Herpes simplex virus 1 infection 💬 70 genes, 80 drugs (DrugBank) and 107 diseases |
IL1B [1] IL1B 💬Herpes simplex virus 1 infection
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Canakinumab Canakinumab 💬Herpes simplex virus 1 infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬14. Herpes simplex virus 1 infection
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15 | Human cytomegalovirus infection 💬 64 genes, 114 drugs (DrugBank) and 130 diseases |
IL1B [1] IL1B 💬Human cytomegalovirus infection
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Canakinumab Canakinumab 💬Human cytomegalovirus infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬15. Human cytomegalovirus infection
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16 | IL-17 signaling pathway 💬 20 genes, 61 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬IL-17 signaling pathway
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Canakinumab Canakinumab 💬IL-17 signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬16. IL-17 signaling pathway
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17 | Inflammatory bowel disease 💬 37 genes, 46 drugs (DrugBank) and 70 diseases |
IL1B [1] IL1B 💬Inflammatory bowel disease
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Canakinumab Canakinumab 💬Inflammatory bowel disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬17. Inflammatory bowel disease
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18 | Inflammatory mediator regulation of TRP channels 💬 25 genes, 53 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬Inflammatory mediator regulation of TRP channels
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Canakinumab Canakinumab 💬Inflammatory mediator regulation of TRP channels
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬18. Inflammatory mediator regulation of TRP channels
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19 | Influenza A 💬 65 genes, 78 drugs (DrugBank) and 98 diseases |
IL1B [1] IL1B 💬Influenza A
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Canakinumab Canakinumab 💬Influenza A
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬19. Influenza A
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20 | Legionellosis 💬 9 genes, 23 drugs (DrugBank) and 64 diseases |
IL1B [1] IL1B 💬Legionellosis
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Canakinumab Canakinumab 💬Legionellosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬20. Legionellosis
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21 | Leishmaniasis 💬 40 genes, 68 drugs (DrugBank) and 102 diseases |
IL1B [1] IL1B 💬Leishmaniasis
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Canakinumab Canakinumab 💬Leishmaniasis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬21. Leishmaniasis
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22 | Lipid and atherosclerosis 💬 51 genes, 71 drugs (DrugBank) and 103 diseases |
IL1B [1] IL1B 💬Lipid and atherosclerosis
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Canakinumab Canakinumab 💬Lipid and atherosclerosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬22. Lipid and atherosclerosis
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23 | Malaria 💬 16 genes, 32 drugs (DrugBank) and 71 diseases |
IL1B [1] IL1B 💬Malaria
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Canakinumab Canakinumab 💬Malaria
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬23. Malaria
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24 | MAPK signaling pathway 💬 65 genes, 98 drugs (DrugBank) and 109 diseases |
IL1B [1] IL1B 💬MAPK signaling pathway
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Canakinumab Canakinumab 💬MAPK signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬24. MAPK signaling pathway
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25 | Measles 💬 42 genes, 63 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬Measles
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Canakinumab Canakinumab 💬Measles
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬25. Measles
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26 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬Necroptosis
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Canakinumab Canakinumab 💬Necroptosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬26. Necroptosis
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27 | NF-kappa B signaling pathway 💬 22 genes, 77 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬NF-kappa B signaling pathway
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Canakinumab Canakinumab 💬NF-kappa B signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬27. NF-kappa B signaling pathway
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28 | NOD-like receptor signaling pathway 💬 32 genes, 51 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬NOD-like receptor signaling pathway
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Canakinumab Canakinumab 💬NOD-like receptor signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬28. NOD-like receptor signaling pathway
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29 | Non-alcoholic fatty liver disease 💬 23 genes, 52 drugs (DrugBank) and 95 diseases |
IL1B [1] IL1B 💬Non-alcoholic fatty liver disease
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Canakinumab Canakinumab 💬Non-alcoholic fatty liver disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬29. Non-alcoholic fatty liver disease
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30 | Osteoclast differentiation 💬 38 genes, 86 drugs (DrugBank) and 102 diseases |
IL1B [1] IL1B 💬Osteoclast differentiation
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Canakinumab Canakinumab 💬Osteoclast differentiation
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬30. Osteoclast differentiation
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31 | Pathogenic Escherichia coli infection 💬 28 genes, 43 drugs (DrugBank) and 78 diseases |
IL1B [1] IL1B 💬Pathogenic Escherichia coli infection
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Canakinumab Canakinumab 💬Pathogenic Escherichia coli infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬31. Pathogenic Escherichia coli infection
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32 | Pathways of neurodegeneration - multiple diseases 💬 63 genes, 138 drugs (DrugBank) and 132 diseases |
IL1B [1] IL1B 💬Pathways of neurodegeneration - multiple diseases
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Canakinumab Canakinumab 💬Pathways of neurodegeneration - multiple diseases
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬32. Pathways of neurodegeneration - multiple diseases
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33 | Pertussis 💬 22 genes, 46 drugs (DrugBank) and 73 diseases |
IL1B [1] IL1B 💬Pertussis
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Canakinumab Canakinumab 💬Pertussis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬33. Pertussis
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34 | Prion disease 💬 41 genes, 74 drugs (DrugBank) and 114 diseases |
IL1B [1] IL1B 💬Prion disease
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Canakinumab Canakinumab 💬Prion disease
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬34. Prion disease
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35 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬Rheumatoid arthritis
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Canakinumab Canakinumab 💬Rheumatoid arthritis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬35. Rheumatoid arthritis
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36 | Salmonella infection 💬 30 genes, 46 drugs (DrugBank) and 75 diseases |
IL1B [1] IL1B 💬Salmonella infection
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Canakinumab Canakinumab 💬Salmonella infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬36. Salmonella infection
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37 | Shigellosis 💬 29 genes, 51 drugs (DrugBank) and 92 diseases |
IL1B [1] IL1B 💬Shigellosis
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Canakinumab Canakinumab 💬Shigellosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬37. Shigellosis
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38 | Th17 cell differentiation 💬 56 genes, 80 drugs (DrugBank) and 108 diseases |
IL1B [1] IL1B 💬Th17 cell differentiation
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Canakinumab Canakinumab 💬Th17 cell differentiation
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬38. Th17 cell differentiation
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39 | TNF signaling pathway 💬 23 genes, 61 drugs (DrugBank) and 90 diseases |
IL1B [1] IL1B 💬TNF signaling pathway
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Canakinumab Canakinumab 💬TNF signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬39. TNF signaling pathway
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40 | Toll-like receptor signaling pathway 💬 41 genes, 65 drugs (DrugBank) and 79 diseases |
IL1B [1] IL1B 💬Toll-like receptor signaling pathway
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Canakinumab Canakinumab 💬Toll-like receptor signaling pathway
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬40. Toll-like receptor signaling pathway
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41 | Tuberculosis 💬 66 genes, 73 drugs (DrugBank) and 98 diseases |
IL1B [1] IL1B 💬Tuberculosis
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Canakinumab Canakinumab 💬Tuberculosis
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬41. Tuberculosis
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42 | Type I diabetes mellitus 💬 32 genes, 25 drugs (DrugBank) and 70 diseases |
IL1B [1] IL1B 💬Type I diabetes mellitus
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Canakinumab Canakinumab 💬Type I diabetes mellitus
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬42. Type I diabetes mellitus
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43 | Yersinia infection 💬 27 genes, 45 drugs (DrugBank) and 79 diseases |
IL1B [1] IL1B 💬Yersinia infection
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Canakinumab Canakinumab 💬Yersinia infection
| Canakinumab | 046 [11] 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬43. Yersinia infection
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African trypanosomiasis
10 genes, 24 drugs (DrugBank) and 62 diseases
AGE-RAGE signaling pathway in diabetic complications
28 genes, 55 drugs (DrugBank) and 96 diseases
Alcoholic liver disease
42 genes, 54 drugs (DrugBank) and 91 diseases
Alzheimer disease
59 genes, 132 drugs (DrugBank) and 129 diseases
Amoebiasis
20 genes, 32 drugs (DrugBank) and 71 diseases
C-type lectin receptor signaling pathway
27 genes, 66 drugs (DrugBank) and 102 diseases
Chagas disease
31 genes, 56 drugs (DrugBank) and 87 diseases
Coronavirus disease - COVID-19
54 genes, 108 drugs (DrugBank) and 105 diseases
Cytokine-cytokine receptor interaction
89 genes, 142 drugs (DrugBank) and 110 diseases
Cytosolic DNA-sensing pathway
20 genes, 16 drugs (DrugBank) and 31 diseases
Fluid shear stress and atherosclerosis
34 genes, 59 drugs (DrugBank) and 93 diseases
Graft-versus-host disease
28 genes, 25 drugs (DrugBank) and 64 diseases
Hematopoietic cell lineage
53 genes, 95 drugs (DrugBank) and 101 diseases
Herpes simplex virus 1 infection
70 genes, 80 drugs (DrugBank) and 107 diseases
Human cytomegalovirus infection
64 genes, 114 drugs (DrugBank) and 130 diseases
IL-17 signaling pathway
20 genes, 61 drugs (DrugBank) and 86 diseases
Inflammatory bowel disease
37 genes, 46 drugs (DrugBank) and 70 diseases
Inflammatory mediator regulation of TRP channels
25 genes, 53 drugs (DrugBank) and 65 diseases
Influenza A
65 genes, 78 drugs (DrugBank) and 98 diseases
Legionellosis
9 genes, 23 drugs (DrugBank) and 64 diseases
Leishmaniasis
40 genes, 68 drugs (DrugBank) and 102 diseases
Lipid and atherosclerosis
51 genes, 71 drugs (DrugBank) and 103 diseases
Malaria
16 genes, 32 drugs (DrugBank) and 71 diseases
MAPK signaling pathway
65 genes, 98 drugs (DrugBank) and 109 diseases
Measles
42 genes, 63 drugs (DrugBank) and 68 diseases
Necroptosis
32 genes, 52 drugs (DrugBank) and 77 diseases
NF-kappa B signaling pathway
22 genes, 77 drugs (DrugBank) and 91 diseases
NOD-like receptor signaling pathway
32 genes, 51 drugs (DrugBank) and 74 diseases
Non-alcoholic fatty liver disease
23 genes, 52 drugs (DrugBank) and 95 diseases
Osteoclast differentiation
38 genes, 86 drugs (DrugBank) and 102 diseases
Pathogenic Escherichia coli infection
28 genes, 43 drugs (DrugBank) and 78 diseases
Pathways of neurodegeneration - multiple diseases
63 genes, 138 drugs (DrugBank) and 132 diseases
Pertussis
22 genes, 46 drugs (DrugBank) and 73 diseases
Prion disease
41 genes, 74 drugs (DrugBank) and 114 diseases
Rheumatoid arthritis
38 genes, 59 drugs (DrugBank) and 87 diseases
Salmonella infection
30 genes, 46 drugs (DrugBank) and 75 diseases
Shigellosis
29 genes, 51 drugs (DrugBank) and 92 diseases
Th17 cell differentiation
56 genes, 80 drugs (DrugBank) and 108 diseases
TNF signaling pathway
23 genes, 61 drugs (DrugBank) and 90 diseases
Toll-like receptor signaling pathway
41 genes, 65 drugs (DrugBank) and 79 diseases
Tuberculosis
66 genes, 73 drugs (DrugBank) and 98 diseases
Type I diabetes mellitus
32 genes, 25 drugs (DrugBank) and 70 diseases
Yersinia infection
27 genes, 45 drugs (DrugBank) and 79 diseases