Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adherens junction 💬	[1] FGFR1 💬 Adherens junction × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Adherens junction × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 1. Adherens junction × Disease ID Name 276 Achondroplasia;
2	Adherens junction 💬	[1] FGFR1 💬 Adherens junction × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Adherens junction × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 1. Adherens junction × Disease ID Name 276 Achondroplasia;
3	Bladder cancer 💬	[1] FGFR3 💬 Bladder cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Bladder cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 3. Bladder cancer × Disease ID Name 276 Achondroplasia;
4	Bladder cancer 💬	[1] FGFR3 💬 Bladder cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Bladder cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 3. Bladder cancer × Disease ID Name 276 Achondroplasia;
5	Bladder cancer 💬	[1] FGFR3 💬 Bladder cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Bladder cancer × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 5. Bladder cancer × Disease ID Name 276 Achondroplasia;
6	Breast cancer 💬	[1] FGFR1 💬 Breast cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Breast cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 6. Breast cancer × Disease ID Name 276 Achondroplasia;
7	Breast cancer 💬	[1] FGFR1 💬 Breast cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Breast cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 6. Breast cancer × Disease ID Name 276 Achondroplasia;
8	Cadherin signaling 💬	[1] FGFR1 💬 Cadherin signaling × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Cadherin signaling × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 8. Cadherin signaling × Disease ID Name 276 Achondroplasia;
9	Cadherin signaling 💬	[1] FGFR1 💬 Cadherin signaling × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Cadherin signaling × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 8. Cadherin signaling × Disease ID Name 276 Achondroplasia;
10	Calcium signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 Calcium signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Calcium signaling pathway × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 10. Calcium signaling pathway × Disease ID Name 276 Achondroplasia;
11	Calcium signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 Calcium signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Calcium signaling pathway × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 10. Calcium signaling pathway × Disease ID Name 276 Achondroplasia;
12	Calcium signaling pathway 💬	[1] FGFR3 💬 Calcium signaling pathway × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Calcium signaling pathway × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 12. Calcium signaling pathway × Disease ID Name 276 Achondroplasia;
13	Central carbon metabolism in cancer 💬	[3] FGFR1, FGFR2, FGFR3 💬 Central carbon metabolism in cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Central carbon metabolism in cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 13. Central carbon metabolism in cancer × Disease ID Name 276 Achondroplasia;
14	Central carbon metabolism in cancer 💬	[3] FGFR1, FGFR2, FGFR3 💬 Central carbon metabolism in cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Central carbon metabolism in cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 13. Central carbon metabolism in cancer × Disease ID Name 276 Achondroplasia;
15	Central carbon metabolism in cancer 💬	[1] FGFR3 💬 Central carbon metabolism in cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Central carbon metabolism in cancer × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 15. Central carbon metabolism in cancer × Disease ID Name 276 Achondroplasia;
16	cGMP-PKG signaling pathway 💬	[1] NPR2 💬 cGMP-PKG signaling pathway × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Navepegritide 💬 cGMP-PKG signaling pathway × Name Other Names Navepegritide Yuviwel	Navepegritide	[1] 276 💬 16. cGMP-PKG signaling pathway × Disease ID Name 276 Achondroplasia;
17	cGMP-PKG signaling pathway 💬	[1] NPR2 💬 cGMP-PKG signaling pathway × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Vosoritide 💬 cGMP-PKG signaling pathway × Name Other Names Vosoritide Voxzogo	Vosoritide	[3] 19, 195, 276 💬 17. cGMP-PKG signaling pathway × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 195 Noonan syndrome; 276 Achondroplasia;
18	Cytokine-cytokine receptor interaction 💬	[1] GHR 💬 Cytokine-cytokine receptor interaction × Name Full Name GHR growth hormone receptor isoform 1 precursor	Lonapegsomatropin 💬 Cytokine-cytokine receptor interaction × Name Other Names Lonapegsomatropin Lonapegsomatropin-tcgd Skytrofa	Lonapegsomatropin	[1] 276 💬 18. Cytokine-cytokine receptor interaction × Disease ID Name 276 Achondroplasia;
19	Endocytosis 💬	[2] FGFR2, FGFR3 💬 Endocytosis × Name Full Name FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Endocytosis × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 19. Endocytosis × Disease ID Name 276 Achondroplasia;
20	Endocytosis 💬	[2] FGFR2, FGFR3 💬 Endocytosis × Name Full Name FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Endocytosis × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 19. Endocytosis × Disease ID Name 276 Achondroplasia;
21	Endocytosis 💬	[1] FGFR3 💬 Endocytosis × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Endocytosis × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 21. Endocytosis × Disease ID Name 276 Achondroplasia;
22	Gastric cancer 💬	[1] FGFR2 💬 Gastric cancer × Name Full Name FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor	Infigratinib 💬 Gastric cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 22. Gastric cancer × Disease ID Name 276 Achondroplasia;
23	Gastric cancer 💬	[1] FGFR2 💬 Gastric cancer × Name Full Name FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor	Infigratinib phosphate 💬 Gastric cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 22. Gastric cancer × Disease ID Name 276 Achondroplasia;
24	Growth hormone synthesis, secretion and action 💬	[1] GHR 💬 Growth hormone synthesis, secretion and action × Name Full Name GHR growth hormone receptor isoform 1 precursor	Lonapegsomatropin 💬 Growth hormone synthesis, secretion and action × Name Other Names Lonapegsomatropin Lonapegsomatropin-tcgd Skytrofa	Lonapegsomatropin	[1] 276 💬 24. Growth hormone synthesis, secretion and action × Disease ID Name 276 Achondroplasia;
25	Hormone signaling 💬	[1] GHR 💬 Hormone signaling × Name Full Name GHR growth hormone receptor isoform 1 precursor	Lonapegsomatropin 💬 Hormone signaling × Name Other Names Lonapegsomatropin Lonapegsomatropin-tcgd Skytrofa	Lonapegsomatropin	[1] 276 💬 25. Hormone signaling × Disease ID Name 276 Achondroplasia;
26	Hormone signaling 💬	[1] NPR2 💬 Hormone signaling × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Navepegritide 💬 Hormone signaling × Name Other Names Navepegritide Yuviwel	Navepegritide	[1] 276 💬 26. Hormone signaling × Disease ID Name 276 Achondroplasia;
27	Hormone signaling 💬	[1] NPR2 💬 Hormone signaling × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Vosoritide 💬 Hormone signaling × Name Other Names Vosoritide Voxzogo	Vosoritide	[3] 19, 195, 276 💬 27. Hormone signaling × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 195 Noonan syndrome; 276 Achondroplasia;
28	IgSF CAM signaling 💬	[1] FGFR1 💬 IgSF CAM signaling × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 IgSF CAM signaling × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 28. IgSF CAM signaling × Disease ID Name 276 Achondroplasia;
29	IgSF CAM signaling 💬	[1] FGFR1 💬 IgSF CAM signaling × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 IgSF CAM signaling × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 28. IgSF CAM signaling × Disease ID Name 276 Achondroplasia;
30	JAK-STAT signaling pathway 💬	[1] GHR 💬 JAK-STAT signaling pathway × Name Full Name GHR growth hormone receptor isoform 1 precursor	Lonapegsomatropin 💬 JAK-STAT signaling pathway × Name Other Names Lonapegsomatropin Lonapegsomatropin-tcgd Skytrofa	Lonapegsomatropin	[1] 276 💬 30. JAK-STAT signaling pathway × Disease ID Name 276 Achondroplasia;
31	MAPK signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 MAPK signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 MAPK signaling pathway × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 31. MAPK signaling pathway × Disease ID Name 276 Achondroplasia;
32	MAPK signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 MAPK signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 MAPK signaling pathway × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 31. MAPK signaling pathway × Disease ID Name 276 Achondroplasia;
33	MAPK signaling pathway 💬	[1] FGFR3 💬 MAPK signaling pathway × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 MAPK signaling pathway × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 33. MAPK signaling pathway × Disease ID Name 276 Achondroplasia;
34	Melanoma 💬	[1] FGFR1 💬 Melanoma × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Melanoma × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 34. Melanoma × Disease ID Name 276 Achondroplasia;
35	Melanoma 💬	[1] FGFR1 💬 Melanoma × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Melanoma × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 34. Melanoma × Disease ID Name 276 Achondroplasia;
36	MicroRNAs in cancer 💬	[1] FGFR3 💬 MicroRNAs in cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 MicroRNAs in cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 36. MicroRNAs in cancer × Disease ID Name 276 Achondroplasia;
37	MicroRNAs in cancer 💬	[1] FGFR3 💬 MicroRNAs in cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 MicroRNAs in cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 36. MicroRNAs in cancer × Disease ID Name 276 Achondroplasia;
38	MicroRNAs in cancer 💬	[1] FGFR3 💬 MicroRNAs in cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 MicroRNAs in cancer × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 38. MicroRNAs in cancer × Disease ID Name 276 Achondroplasia;
39	Neuroactive ligand-receptor interaction 💬	[1] GHR 💬 Neuroactive ligand-receptor interaction × Name Full Name GHR growth hormone receptor isoform 1 precursor	Lonapegsomatropin 💬 Neuroactive ligand-receptor interaction × Name Other Names Lonapegsomatropin Lonapegsomatropin-tcgd Skytrofa	Lonapegsomatropin	[1] 276 💬 39. Neuroactive ligand-receptor interaction × Disease ID Name 276 Achondroplasia;
40	Oxytocin signaling pathway 💬	[1] NPR2 💬 Oxytocin signaling pathway × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Navepegritide 💬 Oxytocin signaling pathway × Name Other Names Navepegritide Yuviwel	Navepegritide	[1] 276 💬 40. Oxytocin signaling pathway × Disease ID Name 276 Achondroplasia;
41	Oxytocin signaling pathway 💬	[1] NPR2 💬 Oxytocin signaling pathway × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Vosoritide 💬 Oxytocin signaling pathway × Name Other Names Vosoritide Voxzogo	Vosoritide	[3] 19, 195, 276 💬 41. Oxytocin signaling pathway × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 195 Noonan syndrome; 276 Achondroplasia;
42	Parathyroid hormone synthesis, secretion and action 💬	[1] FGFR1 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 42. Parathyroid hormone synthesis, secretion and action × Disease ID Name 276 Achondroplasia;
43	Parathyroid hormone synthesis, secretion and action 💬	[1] FGFR1 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 42. Parathyroid hormone synthesis, secretion and action × Disease ID Name 276 Achondroplasia;
44	Pathways in cancer 💬	[3] FGFR1, FGFR2, FGFR3 💬 Pathways in cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Pathways in cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 44. Pathways in cancer × Disease ID Name 276 Achondroplasia;
45	Pathways in cancer 💬	[3] FGFR1, FGFR2, FGFR3 💬 Pathways in cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Pathways in cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 44. Pathways in cancer × Disease ID Name 276 Achondroplasia;
46	Pathways in cancer 💬	[1] FGFR3 💬 Pathways in cancer × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Pathways in cancer × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 46. Pathways in cancer × Disease ID Name 276 Achondroplasia;
47	PI3K-Akt signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 PI3K-Akt signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 PI3K-Akt signaling pathway × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 47. PI3K-Akt signaling pathway × Disease ID Name 276 Achondroplasia;
48	PI3K-Akt signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 PI3K-Akt signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 PI3K-Akt signaling pathway × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 47. PI3K-Akt signaling pathway × Disease ID Name 276 Achondroplasia;
49	PI3K-Akt signaling pathway 💬	[1] FGFR3 💬 PI3K-Akt signaling pathway × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 PI3K-Akt signaling pathway × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 49. PI3K-Akt signaling pathway × Disease ID Name 276 Achondroplasia;
50	PI3K-Akt signaling pathway 💬	[1] GHR 💬 PI3K-Akt signaling pathway × Name Full Name GHR growth hormone receptor isoform 1 precursor	Lonapegsomatropin 💬 PI3K-Akt signaling pathway × Name Other Names Lonapegsomatropin Lonapegsomatropin-tcgd Skytrofa	Lonapegsomatropin	[1] 276 💬 50. PI3K-Akt signaling pathway × Disease ID Name 276 Achondroplasia;
51	Prostate cancer 💬	[2] FGFR1, FGFR2 💬 Prostate cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor	Infigratinib 💬 Prostate cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 51. Prostate cancer × Disease ID Name 276 Achondroplasia;
52	Prostate cancer 💬	[2] FGFR1, FGFR2 💬 Prostate cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor	Infigratinib phosphate 💬 Prostate cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 51. Prostate cancer × Disease ID Name 276 Achondroplasia;
53	Proteoglycans in cancer 💬	[1] FGFR1 💬 Proteoglycans in cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Proteoglycans in cancer × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 53. Proteoglycans in cancer × Disease ID Name 276 Achondroplasia;
54	Proteoglycans in cancer 💬	[1] FGFR1 💬 Proteoglycans in cancer × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Proteoglycans in cancer × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 53. Proteoglycans in cancer × Disease ID Name 276 Achondroplasia;
55	Purine metabolism 💬	[1] NPR2 💬 Purine metabolism × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Navepegritide 💬 Purine metabolism × Name Other Names Navepegritide Yuviwel	Navepegritide	[1] 276 💬 55. Purine metabolism × Disease ID Name 276 Achondroplasia;
56	Purine metabolism 💬	[1] NPR2 💬 Purine metabolism × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Vosoritide 💬 Purine metabolism × Name Other Names Vosoritide Voxzogo	Vosoritide	[3] 19, 195, 276 💬 56. Purine metabolism × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 195 Noonan syndrome; 276 Achondroplasia;
57	Rap1 signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 Rap1 signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Rap1 signaling pathway × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 57. Rap1 signaling pathway × Disease ID Name 276 Achondroplasia;
58	Rap1 signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 Rap1 signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Rap1 signaling pathway × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 57. Rap1 signaling pathway × Disease ID Name 276 Achondroplasia;
59	Rap1 signaling pathway 💬	[1] FGFR3 💬 Rap1 signaling pathway × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Rap1 signaling pathway × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 59. Rap1 signaling pathway × Disease ID Name 276 Achondroplasia;
60	Ras signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 Ras signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Ras signaling pathway × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 60. Ras signaling pathway × Disease ID Name 276 Achondroplasia;
61	Ras signaling pathway 💬	[3] FGFR1, FGFR2, FGFR3 💬 Ras signaling pathway × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Ras signaling pathway × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 60. Ras signaling pathway × Disease ID Name 276 Achondroplasia;
62	Ras signaling pathway 💬	[1] FGFR3 💬 Ras signaling pathway × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Ras signaling pathway × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 62. Ras signaling pathway × Disease ID Name 276 Achondroplasia;
63	Regulation of actin cytoskeleton 💬	[3] FGFR1, FGFR2, FGFR3 💬 Regulation of actin cytoskeleton × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Regulation of actin cytoskeleton × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 63. Regulation of actin cytoskeleton × Disease ID Name 276 Achondroplasia;
64	Regulation of actin cytoskeleton 💬	[3] FGFR1, FGFR2, FGFR3 💬 Regulation of actin cytoskeleton × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Regulation of actin cytoskeleton × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 63. Regulation of actin cytoskeleton × Disease ID Name 276 Achondroplasia;
65	Regulation of actin cytoskeleton 💬	[1] FGFR3 💬 Regulation of actin cytoskeleton × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Regulation of actin cytoskeleton × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 65. Regulation of actin cytoskeleton × Disease ID Name 276 Achondroplasia;
66	Signaling pathways regulating pluripotency of stem cells 💬	[3] FGFR1, FGFR2, FGFR3 💬 Signaling pathways regulating pluripotency of stem cells × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 66. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 276 Achondroplasia;
67	Signaling pathways regulating pluripotency of stem cells 💬	[3] FGFR1, FGFR2, FGFR3 💬 Signaling pathways regulating pluripotency of stem cells × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor FGFR2 fibroblast growth factor receptor 2 isoform 1 precursor FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Infigratinib phosphate 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 66. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 276 Achondroplasia;
68	Signaling pathways regulating pluripotency of stem cells 💬	[1] FGFR3 💬 Signaling pathways regulating pluripotency of stem cells × Name Full Name FGFR3 fibroblast growth factor receptor 3 isoform 1 precursor	Recifercept 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Recifercept Recifercept	Recifercept	[1] 276 💬 68. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 276 Achondroplasia;
69	Thermogenesis 💬	[1] FGFR1 💬 Thermogenesis × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib 💬 Thermogenesis × Name Other Names Infigratinib Infigratinib	Infigratinib	[1] 276 💬 69. Thermogenesis × Disease ID Name 276 Achondroplasia;
70	Thermogenesis 💬	[1] FGFR1 💬 Thermogenesis × Name Full Name FGFR1 fibroblast growth factor receptor 1 isoform 1 precursor	Infigratinib phosphate 💬 Thermogenesis × Name Other Names Infigratinib phosphate Truseltiq	Infigratinib	[1] 276 💬 69. Thermogenesis × Disease ID Name 276 Achondroplasia;
71	Vascular smooth muscle contraction 💬	[1] NPR2 💬 Vascular smooth muscle contraction × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Navepegritide 💬 Vascular smooth muscle contraction × Name Other Names Navepegritide Yuviwel	Navepegritide	[1] 276 💬 71. Vascular smooth muscle contraction × Disease ID Name 276 Achondroplasia;
72	Vascular smooth muscle contraction 💬	[1] NPR2 💬 Vascular smooth muscle contraction × Name Full Name NPR2 atrial natriuretic peptide receptor 2 isoform 1 precursor	Vosoritide 💬 Vascular smooth muscle contraction × Name Other Names Vosoritide Voxzogo	Vosoritide	[3] 19, 195, 276 💬 72. Vascular smooth muscle contraction × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 195 Noonan syndrome; 276 Achondroplasia;

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