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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Adipocytokine signaling pathway 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Alcoholic liver disease 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

cAMP signaling pathway 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Chemical carcinogenesis - receptor activation 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Diabetic cardiomyopathy 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Glucagon signaling pathway 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Hepatitis C 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Insulin resistance 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

Non-alcoholic fatty liver disease 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;

PPAR signaling pathway 💬

[1] NR1C1 💬

Bezafibrate 💬

Bezafibrate

[8] 20, 93, 94, 160, 296, 316, 324, 344 💬

Disease ID	Name
20	Adrenoleukodystrophy;ALD;Childhood cerebral ALD;CCALD;Adolescent cerebral ALD;AdoCALD;AdolCALD;Adrenomyeloneuropathy;AMN;Adult cerebral ALD;ACALD;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
94	Primary sclerosing cholangitis;PSC;
160	Congenital ichthyosis;Keratinopathic ichthyosis;Epidermolytic ichthyosis;Superficial epidermolytic ichthyosis;Harlequin ichthyosis;Autosomal recessive congenital ichthyosis;Congenital Ichthyosiform Erythroderma;Foliate ichthyosis;Ichthyosis syndrome;Netherton syndrome;Sjogren-Larsson syndrome;Sjögren-Larsson syndrome;Keratitis-ichtyosis-deafness syndrome;KID syndrome;Dorfman-Chanarin syndrome;Neutral lipid storage disease;NLSD;Multiple sulfatase deficiency;Austin disease;Recessive X-linked ichthyosis;RXLI;X-linked recessive ichthyosis;Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature;IBID;Trichothiodystrophy;Follicular ichthyosis;Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome;CHILD syndrome;Conradi-Hunermann-Happle syndrome;Conradi-Hünermann-Happle syndrome;CHHS;
296	Biliary atresia;
316	Carnitine cycle disorder;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Carnitine transporter deficiency;OCTN-2 deficiency;
324	Methylglutaconic aciduria;3-methylglutaconyl-CoA hydratase deficiency;3-methylglutaconic aciduria;3-MGA;3-MGA type I;Barth syndrome;3-MGA type II;Costeff syndrome;3-MGA type III;
344	Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;