Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 ABC transporters 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
4 AMPK signaling pathway 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
5 Bile secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
6 Calcium signaling pathway 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
7 Calcium signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
8 cAMP signaling pathway 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
9 cAMP signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
10 cAMP signaling pathway 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
11 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
12 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
13 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
14 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
15 Gastric acid secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
16 Hormone signaling 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
17 Hormone signaling 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
18 Neuroactive ligand signaling 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
19 Neuroactive ligand signaling 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
20 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
21 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
22 Pancreatic secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
23 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
24 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
25 Renin secretion 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
26 Renin secretion 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
27 Salivary secretion 💬
 [1] ADRB2 💬 Albuterol sulfate 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
28 Salivary secretion 💬
 [1] ADRB2 💬 Albuterol 💬 Albuterol [16]  2 ,  3 , 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
29 Tight junction 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬
30 Vibrio cholerae infection 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [2] 299, 340 💬

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