Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||
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| 1 | Alcoholism 💬 29 genes, 81 drugs (DrugBank) and 60 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine Midomafetamine 💬Alcoholism
| Midomafetamine | 072 [1] 72 💬1. Alcoholism
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| 2 | Alcoholism 💬 29 genes, 81 drugs (DrugBank) and 60 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Alcoholism
| Midomafetamine | 072 [1] 72 💬1. Alcoholism
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| 3 | Amphetamine addiction 💬 25 genes, 58 drugs (DrugBank) and 92 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine Midomafetamine 💬Amphetamine addiction
| Midomafetamine | 072 [1] 72 💬3. Amphetamine addiction
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| 4 | Amphetamine addiction 💬 25 genes, 58 drugs (DrugBank) and 92 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Amphetamine addiction
| Midomafetamine | 072 [1] 72 💬3. Amphetamine addiction
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| 5 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
OXTR [1] OXTR 💬Calcium signaling pathway
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Oxytocin Oxytocin 💬Calcium signaling pathway
| Oxytocin | 006 [8] 6 , 70, 72, 127, 168, 193, 206, 226 💬5. Calcium signaling pathway
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| 6 | cAMP signaling pathway 💬 66 genes, 189 drugs (DrugBank) and 130 diseases |
OXTR [1] OXTR 💬cAMP signaling pathway
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Oxytocin Oxytocin 💬cAMP signaling pathway
| Oxytocin | 006 [8] 6 , 70, 72, 127, 168, 193, 206, 226 💬6. cAMP signaling pathway
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| 7 | Circadian entrainment 💬 23 genes, 39 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
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Melatonin Melatonin 💬Circadian entrainment
| Melatonin | 002 [17] 2 , 6 , 8 , 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 202, 265 💬7. Circadian entrainment
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| 8 | Cocaine addiction 💬 15 genes, 66 drugs (DrugBank) and 54 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine Midomafetamine 💬Cocaine addiction
| Midomafetamine | 072 [1] 72 💬8. Cocaine addiction
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| 9 | Cocaine addiction 💬 15 genes, 66 drugs (DrugBank) and 54 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Cocaine addiction
| Midomafetamine | 072 [1] 72 💬8. Cocaine addiction
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| 10 | Complement and coagulation cascades 💬 22 genes, 45 drugs (DrugBank) and 52 diseases |
F8 [1] F8 💬Complement and coagulation cascades
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Desmopressin Desmopressin 💬Complement and coagulation cascades
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬10. Complement and coagulation cascades
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| 11 | Complement and coagulation cascades 💬 22 genes, 45 drugs (DrugBank) and 52 diseases |
F8 [1] F8 💬Complement and coagulation cascades
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Desmopressin acetate Desmopressin acetate 💬Complement and coagulation cascades
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬10. Complement and coagulation cascades
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| 12 | Dopaminergic synapse 💬 31 genes, 102 drugs (DrugBank) and 104 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine Midomafetamine 💬Dopaminergic synapse
| Midomafetamine | 072 [1] 72 💬12. Dopaminergic synapse
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| 13 | Dopaminergic synapse 💬 31 genes, 102 drugs (DrugBank) and 104 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Dopaminergic synapse
| Midomafetamine | 072 [1] 72 💬12. Dopaminergic synapse
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| 14 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬Hormone signaling
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Desmopressin Desmopressin 💬Hormone signaling
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬14. Hormone signaling
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| 15 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬Hormone signaling
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Desmopressin acetate Desmopressin acetate 💬Hormone signaling
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬14. Hormone signaling
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| 16 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬Hormone signaling
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Tolvaptan Tolvaptan 💬Hormone signaling
| Tolvaptan | 067 [4] 67, 72, 86, 225 💬16. Hormone signaling
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| 17 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
OXTR [1] OXTR 💬Hormone signaling
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Oxytocin Oxytocin 💬Hormone signaling
| Oxytocin | 006 [8] 6 , 70, 72, 127, 168, 193, 206, 226 💬17. Hormone signaling
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| 18 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 117 diseases |
SLC18A2 [4] SLC18A2, SLC6A2, SLC6A3, SLC6A4 💬
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Midomafetamine Midomafetamine 💬Neuroactive ligand signaling
| Midomafetamine | 072 [1] 72 💬18. Neuroactive ligand signaling
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| 19 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 117 diseases |
SLC18A2 [4] SLC18A2, SLC6A2, SLC6A3, SLC6A4 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Neuroactive ligand signaling
| Midomafetamine | 072 [1] 72 💬18. Neuroactive ligand signaling
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| 20 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
AVPR2 [1] AVPR2 💬Neuroactive ligand-receptor interaction
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Desmopressin Desmopressin 💬Neuroactive ligand-receptor interaction
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬20. Neuroactive ligand-receptor interaction
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| 21 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
AVPR2 [1] AVPR2 💬Neuroactive ligand-receptor interaction
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Desmopressin acetate Desmopressin acetate 💬Neuroactive ligand-receptor interaction
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬20. Neuroactive ligand-receptor interaction
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| 22 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
AVPR2 [1] AVPR2 💬Neuroactive ligand-receptor interaction
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Tolvaptan Tolvaptan 💬Neuroactive ligand-receptor interaction
| Tolvaptan | 067 [4] 67, 72, 86, 225 💬22. Neuroactive ligand-receptor interaction
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| 23 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬
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Melatonin Melatonin 💬Neuroactive ligand-receptor interaction
| Melatonin | 002 [17] 2 , 6 , 8 , 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 202, 265 💬23. Neuroactive ligand-receptor interaction
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| 24 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
OXTR [1] OXTR 💬Neuroactive ligand-receptor interaction
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Oxytocin Oxytocin 💬Neuroactive ligand-receptor interaction
| Oxytocin | 006 [8] 6 , 70, 72, 127, 168, 193, 206, 226 💬24. Neuroactive ligand-receptor interaction
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| 25 | Oxytocin signaling pathway 💬 35 genes, 80 drugs (DrugBank) and 110 diseases |
OXTR [1] OXTR 💬Oxytocin signaling pathway
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Oxytocin Oxytocin 💬Oxytocin signaling pathway
| Oxytocin | 006 [8] 6 , 70, 72, 127, 168, 193, 206, 226 💬25. Oxytocin signaling pathway
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| 26 | Parkinson disease 💬 24 genes, 76 drugs (DrugBank) and 68 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine Midomafetamine 💬Parkinson disease
| Midomafetamine | 072 [1] 72 💬26. Parkinson disease
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| 27 | Parkinson disease 💬 24 genes, 76 drugs (DrugBank) and 68 diseases |
SLC18A2 [2] SLC18A2, SLC6A3 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Parkinson disease
| Midomafetamine | 072 [1] 72 💬26. Parkinson disease
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| 28 | Pathways of neurodegeneration - multiple diseases 💬 63 genes, 138 drugs (DrugBank) and 132 diseases |
SLC6A3 [1] SLC6A3 💬Pathways of neurodegeneration - multiple diseases
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Midomafetamine Midomafetamine 💬Pathways of neurodegeneration - multiple diseases
| Midomafetamine | 072 [1] 72 💬28. Pathways of neurodegeneration - multiple diseases
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| 29 | Pathways of neurodegeneration - multiple diseases 💬 63 genes, 138 drugs (DrugBank) and 132 diseases |
SLC6A3 [1] SLC6A3 💬Pathways of neurodegeneration - multiple diseases
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Pathways of neurodegeneration - multiple diseases
| Midomafetamine | 072 [1] 72 💬28. Pathways of neurodegeneration - multiple diseases
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| 30 | Phospholipase D signaling pathway 💬 23 genes, 59 drugs (DrugBank) and 82 diseases |
AVPR2 [1] AVPR2 💬Phospholipase D signaling pathway
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Desmopressin Desmopressin 💬Phospholipase D signaling pathway
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬30. Phospholipase D signaling pathway
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| 31 | Phospholipase D signaling pathway 💬 23 genes, 59 drugs (DrugBank) and 82 diseases |
AVPR2 [1] AVPR2 💬Phospholipase D signaling pathway
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Desmopressin acetate Desmopressin acetate 💬Phospholipase D signaling pathway
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬30. Phospholipase D signaling pathway
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| 32 | Phospholipase D signaling pathway 💬 23 genes, 59 drugs (DrugBank) and 82 diseases |
AVPR2 [1] AVPR2 💬Phospholipase D signaling pathway
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Tolvaptan Tolvaptan 💬Phospholipase D signaling pathway
| Tolvaptan | 067 [4] 67, 72, 86, 225 💬32. Phospholipase D signaling pathway
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| 33 | Serotonergic synapse 💬 39 genes, 122 drugs (DrugBank) and 83 diseases |
SLC18A2 [2] SLC18A2, SLC6A4 💬
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Midomafetamine Midomafetamine 💬Serotonergic synapse
| Midomafetamine | 072 [1] 72 💬33. Serotonergic synapse
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| 34 | Serotonergic synapse 💬 39 genes, 122 drugs (DrugBank) and 83 diseases |
SLC18A2 [2] SLC18A2, SLC6A4 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Serotonergic synapse
| Midomafetamine | 072 [1] 72 💬33. Serotonergic synapse
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| 35 | Synaptic vesicle cycle 💬 8 genes, 34 drugs (DrugBank) and 42 diseases |
SLC18A2 [4] SLC18A2, SLC6A2, SLC6A3, SLC6A4 💬
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Midomafetamine Midomafetamine 💬Synaptic vesicle cycle
| Midomafetamine | 072 [1] 72 💬35. Synaptic vesicle cycle
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| 36 | Synaptic vesicle cycle 💬 8 genes, 34 drugs (DrugBank) and 42 diseases |
SLC18A2 [4] SLC18A2, SLC6A2, SLC6A3, SLC6A4 💬
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Midomafetamine hydrochloride Midomafetamine hydrochloride 💬Synaptic vesicle cycle
| Midomafetamine | 072 [1] 72 💬35. Synaptic vesicle cycle
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| 37 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 10 diseases |
AVPR2 [1] AVPR2 💬Vasopressin-regulated water reabsorption
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Desmopressin Desmopressin 💬Vasopressin-regulated water reabsorption
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬37. Vasopressin-regulated water reabsorption
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| 38 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 10 diseases |
AVPR2 [1] AVPR2 💬Vasopressin-regulated water reabsorption
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Desmopressin acetate Desmopressin acetate 💬Vasopressin-regulated water reabsorption
| Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬37. Vasopressin-regulated water reabsorption
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| 39 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 10 diseases |
AVPR2 [1] AVPR2 💬Vasopressin-regulated water reabsorption
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Tolvaptan Tolvaptan 💬Vasopressin-regulated water reabsorption
| Tolvaptan | 067 [4] 67, 72, 86, 225 💬39. Vasopressin-regulated water reabsorption
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Alcoholism
29 genes, 81 drugs (DrugBank) and 60 diseases
Amphetamine addiction
25 genes, 58 drugs (DrugBank) and 92 diseases
Calcium signaling pathway
86 genes, 214 drugs (DrugBank) and 143 diseases
cAMP signaling pathway
66 genes, 189 drugs (DrugBank) and 130 diseases
Circadian entrainment
23 genes, 39 drugs (DrugBank) and 55 diseases
Cocaine addiction
15 genes, 66 drugs (DrugBank) and 54 diseases
Complement and coagulation cascades
22 genes, 45 drugs (DrugBank) and 52 diseases
Dopaminergic synapse
31 genes, 102 drugs (DrugBank) and 104 diseases
Hormone signaling
66 genes, 211 drugs (DrugBank) and 153 diseases
Neuroactive ligand signaling
92 genes, 239 drugs (DrugBank) and 117 diseases
Neuroactive ligand-receptor interaction
158 genes, 364 drugs (DrugBank) and 173 diseases
Oxytocin signaling pathway
35 genes, 80 drugs (DrugBank) and 110 diseases
Parkinson disease
24 genes, 76 drugs (DrugBank) and 68 diseases
Pathways of neurodegeneration - multiple diseases
63 genes, 138 drugs (DrugBank) and 132 diseases
Phospholipase D signaling pathway
23 genes, 59 drugs (DrugBank) and 82 diseases
Serotonergic synapse
39 genes, 122 drugs (DrugBank) and 83 diseases
Synaptic vesicle cycle
8 genes, 34 drugs (DrugBank) and 42 diseases
Vasopressin-regulated water reabsorption
1 gene, 5 drugs (DrugBank) and 10 diseases
