Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adherens junction 💬	[2] EGFR, ERBB2 💬 Adherens junction × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Adherens junction × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 1. Adherens junction × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
2	Adherens junction 💬	[2] EGFR, ERBB2 💬 Adherens junction × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Adherens junction × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 1. Adherens junction × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
3	Alcoholism 💬	[2] DRD1, DRD2 💬 Alcoholism × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine hydrochloride 💬 Alcoholism × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 3. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
4	Alcoholism 💬	[2] DRD1, DRD2 💬 Alcoholism × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine 💬 Alcoholism × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 3. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
5	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Alcoholism × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 5. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
6	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Alcoholism × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 5. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
7	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Alcoholism × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 7. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
8	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 dopamine receptor D2	Ropinirole hydrochloride 💬 Alcoholism × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 8. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
9	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 dopamine receptor D2	Ropinirole 💬 Alcoholism × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 8. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
10	Amphetamine addiction 💬	[1] DRD1 💬 Amphetamine addiction × Name Full Name DRD1 dopamine receptor D1	Dopamine hydrochloride 💬 Amphetamine addiction × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 10. Amphetamine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
11	Amphetamine addiction 💬	[1] DRD1 💬 Amphetamine addiction × Name Full Name DRD1 dopamine receptor D1	Dopamine 💬 Amphetamine addiction × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 10. Amphetamine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
12	Bladder cancer 💬	[2] EGFR, ERBB2 💬 Bladder cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Bladder cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 12. Bladder cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
13	Bladder cancer 💬	[2] EGFR, ERBB2 💬 Bladder cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Bladder cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 12. Bladder cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
14	Breast cancer 💬	[2] EGFR, ERBB2 💬 Breast cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Breast cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 14. Breast cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
15	Breast cancer 💬	[2] EGFR, ERBB2 💬 Breast cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Breast cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 14. Breast cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
16	Breast cancer 💬	[2] ESR1, ESR2 💬 Breast cancer × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomiphene citrate 💬 Breast cancer × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 16. Breast cancer × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
17	Breast cancer 💬	[2] ESR1, ESR2 💬 Breast cancer × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomifene 💬 Breast cancer × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 16. Breast cancer × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
18	Calcium signaling pathway 💬	[2] DRD1, DRD5 💬 Calcium signaling pathway × Name Full Name DRD1 dopamine receptor D1 DRD5 dopamine receptor D5	Dopamine hydrochloride 💬 Calcium signaling pathway × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 18. Calcium signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
19	Calcium signaling pathway 💬	[2] DRD1, DRD5 💬 Calcium signaling pathway × Name Full Name DRD1 dopamine receptor D1 DRD5 dopamine receptor D5	Dopamine 💬 Calcium signaling pathway × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 18. Calcium signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
20	Calcium signaling pathway 💬	[2] EGFR, ERBB2 💬 Calcium signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Calcium signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 20. Calcium signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
21	Calcium signaling pathway 💬	[2] EGFR, ERBB2 💬 Calcium signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Calcium signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 20. Calcium signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
22	cAMP signaling pathway 💬	[3] DRD1, DRD2, DRD5 💬 cAMP signaling pathway × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD5 dopamine receptor D5	Dopamine hydrochloride 💬 cAMP signaling pathway × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 22. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
23	cAMP signaling pathway 💬	[3] DRD1, DRD2, DRD5 💬 cAMP signaling pathway × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD5 dopamine receptor D5	Dopamine 💬 cAMP signaling pathway × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 22. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
24	cAMP signaling pathway 💬	[1] DRD2 💬 cAMP signaling pathway × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 cAMP signaling pathway × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 24. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
25	cAMP signaling pathway 💬	[1] DRD2 💬 cAMP signaling pathway × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 cAMP signaling pathway × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 24. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
26	cAMP signaling pathway 💬	[1] DRD2 💬 cAMP signaling pathway × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 cAMP signaling pathway × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 26. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
27	cAMP signaling pathway 💬	[1] DRD2 💬 cAMP signaling pathway × Name Full Name DRD2 dopamine receptor D2	Ropinirole hydrochloride 💬 cAMP signaling pathway × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 27. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
28	cAMP signaling pathway 💬	[1] DRD2 💬 cAMP signaling pathway × Name Full Name DRD2 dopamine receptor D2	Ropinirole 💬 cAMP signaling pathway × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 27. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
29	cAMP signaling pathway 💬	[3] SSTR1, SSTR2, SSTR5 💬 cAMP signaling pathway × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR5 somatostatin receptor 5	Pasireotide 💬 cAMP signaling pathway × Name Other Names Pasireotide Pasireotide (USAN)	Pasireotide	[4] 67, 74, 75, 77 💬 29. cAMP signaling pathway × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
30	cAMP signaling pathway 💬	[3] SSTR1, SSTR2, SSTR5 💬 cAMP signaling pathway × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR5 somatostatin receptor 5	Pasireotide diaspartate 💬 cAMP signaling pathway × Name Other Names Pasireotide diaspartate Pasireotide diaspartate Signifor (TN) SIGNIFOR	Pasireotide	[4] 67, 74, 75, 77 💬 29. cAMP signaling pathway × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
31	cAMP signaling pathway 💬	[3] SSTR1, SSTR2, SSTR5 💬 cAMP signaling pathway × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR5 somatostatin receptor 5	Pasireotide pamoate 💬 cAMP signaling pathway × Name Other Names Pasireotide pamoate Pasireotide pamoate (JAN) Signifor lar (TN) SIGNIFOR LAR	Pasireotide	[4] 67, 74, 75, 77 💬 29. cAMP signaling pathway × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
32	Central carbon metabolism in cancer 💬	[2] EGFR, ERBB2 💬 Central carbon metabolism in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Central carbon metabolism in cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 32. Central carbon metabolism in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
33	Central carbon metabolism in cancer 💬	[2] EGFR, ERBB2 💬 Central carbon metabolism in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Central carbon metabolism in cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 32. Central carbon metabolism in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
34	Chemical carcinogenesis - reactive oxygen species 💬	[1] EGFR 💬 Chemical carcinogenesis - reactive oxygen species × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Chemical carcinogenesis - reactive oxygen species × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 34. Chemical carcinogenesis - reactive oxygen species × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
35	Chemical carcinogenesis - reactive oxygen species 💬	[1] EGFR 💬 Chemical carcinogenesis - reactive oxygen species × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Chemical carcinogenesis - reactive oxygen species × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 34. Chemical carcinogenesis - reactive oxygen species × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
36	Chemical carcinogenesis - receptor activation 💬	[1] EGFR 💬 Chemical carcinogenesis - receptor activation × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Chemical carcinogenesis - receptor activation × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 36. Chemical carcinogenesis - receptor activation × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
37	Chemical carcinogenesis - receptor activation 💬	[1] EGFR 💬 Chemical carcinogenesis - receptor activation × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Chemical carcinogenesis - receptor activation × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 36. Chemical carcinogenesis - receptor activation × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
38	Chemical carcinogenesis - receptor activation 💬	[2] ESR1, ESR2 💬 Chemical carcinogenesis - receptor activation × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomiphene citrate 💬 Chemical carcinogenesis - receptor activation × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 38. Chemical carcinogenesis - receptor activation × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
39	Chemical carcinogenesis - receptor activation 💬	[2] ESR1, ESR2 💬 Chemical carcinogenesis - receptor activation × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomifene 💬 Chemical carcinogenesis - receptor activation × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 38. Chemical carcinogenesis - receptor activation × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
40	Choline metabolism in cancer 💬	[1] EGFR 💬 Choline metabolism in cancer × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Choline metabolism in cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 40. Choline metabolism in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
41	Choline metabolism in cancer 💬	[1] EGFR 💬 Choline metabolism in cancer × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Choline metabolism in cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 40. Choline metabolism in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
42	Cocaine addiction 💬	[2] DRD1, DRD2 💬 Cocaine addiction × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine hydrochloride 💬 Cocaine addiction × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 42. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
43	Cocaine addiction 💬	[2] DRD1, DRD2 💬 Cocaine addiction × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine 💬 Cocaine addiction × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 42. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
44	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Cocaine addiction × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 44. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
45	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Cocaine addiction × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 44. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
46	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Cocaine addiction × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 46. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
47	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 dopamine receptor D2	Ropinirole hydrochloride 💬 Cocaine addiction × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 47. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
48	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 dopamine receptor D2	Ropinirole 💬 Cocaine addiction × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 47. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
49	Colorectal cancer 💬	[1] EGFR 💬 Colorectal cancer × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Colorectal cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 49. Colorectal cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
50	Colorectal cancer 💬	[1] EGFR 💬 Colorectal cancer × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Colorectal cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 49. Colorectal cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
51	Coronavirus disease - COVID-19 💬	[1] EGFR 💬 Coronavirus disease - COVID-19 × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Coronavirus disease - COVID-19 × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 51. Coronavirus disease - COVID-19 × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
52	Coronavirus disease - COVID-19 💬	[1] EGFR 💬 Coronavirus disease - COVID-19 × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Coronavirus disease - COVID-19 × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 51. Coronavirus disease - COVID-19 × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
53	Cushing syndrome 💬	[1] EGFR 💬 Cushing syndrome × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Cushing syndrome × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 53. Cushing syndrome × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
54	Cushing syndrome 💬	[1] EGFR 💬 Cushing syndrome × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Cushing syndrome × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 53. Cushing syndrome × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
55	Cytokine-cytokine receptor interaction 💬	[1] GHR 💬 Cytokine-cytokine receptor interaction × Name Full Name GHR growth hormone receptor	Somatropin 💬 Cytokine-cytokine receptor interaction × Name Other Names Somatropin Somatropin (USP/INN) Somatropin (genetical recombination) (JAN) Human growth hormone (JAN) Asellacrin (TN) Humatrope (TN) Nutropin (TN) Omnitrope (TN) GENOTROPIN HUMATROPE NORDITROPIN OMNITROPE SEROSTIM SOMATROPIN ZOMACTON	Somatotropin	[28]  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬 55. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 76 Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;Central precocious puberty;Gonadotropin producing pituitary adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 78 Hypopituitarism;Anterior pituitary hypothyroidism; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 187 Kabuki syndrome; 191 Werner syndrome; 193 Prader-Willi syndrome; 195 Noonan syndrome; 238 Vitamin D-resistant rickets;VDRR;Vitamin D-resistant osteomalacia;VDRO;FGF23-related hypophosphatemic disease;FGF23-related hypophosphatemia;Hypophosphatemic rickets/osteomalacia;Vitamin D-resistant rickets;VDRR;Hypophosphatemic rickets;Vitamin D-resistant osteomalacia;VDRO;Hypophosphatemic osteomalacia;Acquired vitamin D-resistant osteomalacia;Acquired VDRO;Tumor-induced osteomalacia;TIO; 246 Methylmalonic acidemia;MMA; 265 Lipodystrophy; 274 Osteogenesis Imperfecta; 276 Achondroplasia; 299 Cystic fibrosis;CF; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
56	Cytokine-cytokine receptor interaction 💬	[1] PRL 💬 Cytokine-cytokine receptor interaction × Name Full Name PRL prolactin	Bromocriptine mesylate 💬 Cytokine-cytokine receptor interaction × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 56. Cytokine-cytokine receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
57	Cytokine-cytokine receptor interaction 💬	[1] PRL 💬 Cytokine-cytokine receptor interaction × Name Full Name PRL prolactin	Bromocriptine 💬 Cytokine-cytokine receptor interaction × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 56. Cytokine-cytokine receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
58	Cytokine-cytokine receptor interaction 💬	[1] PRL 💬 Cytokine-cytokine receptor interaction × Name Full Name PRL prolactin	Cabergoline 💬 Cytokine-cytokine receptor interaction × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 58. Cytokine-cytokine receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
59	Dopaminergic synapse 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopaminergic synapse × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine hydrochloride 💬 Dopaminergic synapse × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 59. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
60	Dopaminergic synapse 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopaminergic synapse × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine 💬 Dopaminergic synapse × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 59. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
61	Dopaminergic synapse 💬	[1] DRD2 💬 Dopaminergic synapse × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Dopaminergic synapse × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 61. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
62	Dopaminergic synapse 💬	[1] DRD2 💬 Dopaminergic synapse × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Dopaminergic synapse × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 61. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
63	Dopaminergic synapse 💬	[1] DRD2 💬 Dopaminergic synapse × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Dopaminergic synapse × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 63. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
64	Dopaminergic synapse 💬	[3] DRD2, DRD3, DRD4 💬 Dopaminergic synapse × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole hydrochloride 💬 Dopaminergic synapse × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 64. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
65	Dopaminergic synapse 💬	[3] DRD2, DRD3, DRD4 💬 Dopaminergic synapse × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole 💬 Dopaminergic synapse × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 64. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
66	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬 Endocrine and other factor-regulated calcium reabsorption × Name Full Name ESR1 estrogen receptor 1	Clomiphene citrate 💬 Endocrine and other factor-regulated calcium reabsorption × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 66. Endocrine and other factor-regulated calcium reabsorption × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
67	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬 Endocrine and other factor-regulated calcium reabsorption × Name Full Name ESR1 estrogen receptor 1	Clomifene 💬 Endocrine and other factor-regulated calcium reabsorption × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 66. Endocrine and other factor-regulated calcium reabsorption × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
68	Endocytosis 💬	[1] EGFR 💬 Endocytosis × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Endocytosis × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 68. Endocytosis × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
69	Endocytosis 💬	[1] EGFR 💬 Endocytosis × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Endocytosis × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 68. Endocytosis × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
70	Endometrial cancer 💬	[2] EGFR, ERBB2 💬 Endometrial cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Endometrial cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 70. Endometrial cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
71	Endometrial cancer 💬	[2] EGFR, ERBB2 💬 Endometrial cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Endometrial cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 70. Endometrial cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
72	Epithelial cell signaling in Helicobacter pylori infection 💬	[1] EGFR 💬 Epithelial cell signaling in Helicobacter pylori infection × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Epithelial cell signaling in Helicobacter pylori infection × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 72. Epithelial cell signaling in Helicobacter pylori infection × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
73	Epithelial cell signaling in Helicobacter pylori infection 💬	[1] EGFR 💬 Epithelial cell signaling in Helicobacter pylori infection × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Epithelial cell signaling in Helicobacter pylori infection × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 72. Epithelial cell signaling in Helicobacter pylori infection × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
74	ErbB signaling pathway 💬	[2] EGFR, ERBB2 💬 ErbB signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 ErbB signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 74. ErbB signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
75	ErbB signaling pathway 💬	[2] EGFR, ERBB2 💬 ErbB signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 ErbB signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 74. ErbB signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
76	Estrogen signaling pathway 💬	[1] EGFR 💬 Estrogen signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Estrogen signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 76. Estrogen signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
77	Estrogen signaling pathway 💬	[1] EGFR 💬 Estrogen signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Estrogen signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 76. Estrogen signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
78	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬 Estrogen signaling pathway × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomiphene citrate 💬 Estrogen signaling pathway × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 78. Estrogen signaling pathway × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
79	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬 Estrogen signaling pathway × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomifene 💬 Estrogen signaling pathway × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 78. Estrogen signaling pathway × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
80	Focal adhesion 💬	[2] EGFR, ERBB2 💬 Focal adhesion × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Focal adhesion × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 80. Focal adhesion × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
81	Focal adhesion 💬	[2] EGFR, ERBB2 💬 Focal adhesion × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Focal adhesion × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 80. Focal adhesion × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
82	FoxO signaling pathway 💬	[1] EGFR 💬 FoxO signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 FoxO signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 82. FoxO signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
83	FoxO signaling pathway 💬	[1] EGFR 💬 FoxO signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 FoxO signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 82. FoxO signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
84	Gap junction 💬	[2] DRD1, DRD2 💬 Gap junction × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine hydrochloride 💬 Gap junction × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 84. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
85	Gap junction 💬	[2] DRD1, DRD2 💬 Gap junction × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine 💬 Gap junction × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 84. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
86	Gap junction 💬	[1] DRD2 💬 Gap junction × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Gap junction × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 86. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
87	Gap junction 💬	[1] DRD2 💬 Gap junction × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Gap junction × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 86. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
88	Gap junction 💬	[1] DRD2 💬 Gap junction × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Gap junction × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 88. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
89	Gap junction 💬	[1] DRD2 💬 Gap junction × Name Full Name DRD2 dopamine receptor D2	Ropinirole hydrochloride 💬 Gap junction × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 89. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
90	Gap junction 💬	[1] DRD2 💬 Gap junction × Name Full Name DRD2 dopamine receptor D2	Ropinirole 💬 Gap junction × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 89. Gap junction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
91	Gap junction 💬	[1] EGFR 💬 Gap junction × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Gap junction × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 91. Gap junction × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
92	Gap junction 💬	[1] EGFR 💬 Gap junction × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Gap junction × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 91. Gap junction × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
93	Gastric acid secretion 💬	[1] SSTR2 💬 Gastric acid secretion × Name Full Name SSTR2 somatostatin receptor 2	Pasireotide 💬 Gastric acid secretion × Name Other Names Pasireotide Pasireotide (USAN)	Pasireotide	[4] 67, 74, 75, 77 💬 93. Gastric acid secretion × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
94	Gastric acid secretion 💬	[1] SSTR2 💬 Gastric acid secretion × Name Full Name SSTR2 somatostatin receptor 2	Pasireotide diaspartate 💬 Gastric acid secretion × Name Other Names Pasireotide diaspartate Pasireotide diaspartate Signifor (TN) SIGNIFOR	Pasireotide	[4] 67, 74, 75, 77 💬 93. Gastric acid secretion × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
95	Gastric acid secretion 💬	[1] SSTR2 💬 Gastric acid secretion × Name Full Name SSTR2 somatostatin receptor 2	Pasireotide pamoate 💬 Gastric acid secretion × Name Other Names Pasireotide pamoate Pasireotide pamoate (JAN) Signifor lar (TN) SIGNIFOR LAR	Pasireotide	[4] 67, 74, 75, 77 💬 93. Gastric acid secretion × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
96	Gastric cancer 💬	[2] EGFR, ERBB2 💬 Gastric cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Gastric cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 96. Gastric cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
97	Gastric cancer 💬	[2] EGFR, ERBB2 💬 Gastric cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Gastric cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 96. Gastric cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
98	Glioma 💬	[1] EGFR 💬 Glioma × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Glioma × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 98. Glioma × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
99	Glioma 💬	[1] EGFR 💬 Glioma × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Glioma × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 98. Glioma × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
100	GnRH secretion 💬	[1] ESR2 💬 GnRH secretion × Name Full Name ESR2 estrogen receptor 2	Clomiphene citrate 💬 GnRH secretion × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 100. GnRH secretion × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
101	GnRH secretion 💬	[1] ESR2 💬 GnRH secretion × Name Full Name ESR2 estrogen receptor 2	Clomifene 💬 GnRH secretion × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 100. GnRH secretion × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
102	GnRH signaling pathway 💬	[1] EGFR 💬 GnRH signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 GnRH signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 102. GnRH signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
103	GnRH signaling pathway 💬	[1] EGFR 💬 GnRH signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 GnRH signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 102. GnRH signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
104	Growth hormone synthesis, secretion and action 💬	[1] GHR 💬 Growth hormone synthesis, secretion and action × Name Full Name GHR growth hormone receptor	Somatropin 💬 Growth hormone synthesis, secretion and action × Name Other Names Somatropin Somatropin (USP/INN) Somatropin (genetical recombination) (JAN) Human growth hormone (JAN) Asellacrin (TN) Humatrope (TN) Nutropin (TN) Omnitrope (TN) GENOTROPIN HUMATROPE NORDITROPIN OMNITROPE SEROSTIM SOMATROPIN ZOMACTON	Somatotropin	[28]  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬 104. Growth hormone synthesis, secretion and action × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 76 Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;Central precocious puberty;Gonadotropin producing pituitary adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 78 Hypopituitarism;Anterior pituitary hypothyroidism; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 187 Kabuki syndrome; 191 Werner syndrome; 193 Prader-Willi syndrome; 195 Noonan syndrome; 238 Vitamin D-resistant rickets;VDRR;Vitamin D-resistant osteomalacia;VDRO;FGF23-related hypophosphatemic disease;FGF23-related hypophosphatemia;Hypophosphatemic rickets/osteomalacia;Vitamin D-resistant rickets;VDRR;Hypophosphatemic rickets;Vitamin D-resistant osteomalacia;VDRO;Hypophosphatemic osteomalacia;Acquired vitamin D-resistant osteomalacia;Acquired VDRO;Tumor-induced osteomalacia;TIO; 246 Methylmalonic acidemia;MMA; 265 Lipodystrophy; 274 Osteogenesis Imperfecta; 276 Achondroplasia; 299 Cystic fibrosis;CF; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
105	Growth hormone synthesis, secretion and action 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Growth hormone synthesis, secretion and action × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide 💬 Growth hormone synthesis, secretion and action × Name Other Names Pasireotide Pasireotide (USAN)	Pasireotide	[4] 67, 74, 75, 77 💬 105. Growth hormone synthesis, secretion and action × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
106	Growth hormone synthesis, secretion and action 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Growth hormone synthesis, secretion and action × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide diaspartate 💬 Growth hormone synthesis, secretion and action × Name Other Names Pasireotide diaspartate Pasireotide diaspartate Signifor (TN) SIGNIFOR	Pasireotide	[4] 67, 74, 75, 77 💬 105. Growth hormone synthesis, secretion and action × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
107	Growth hormone synthesis, secretion and action 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Growth hormone synthesis, secretion and action × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide pamoate 💬 Growth hormone synthesis, secretion and action × Name Other Names Pasireotide pamoate Pasireotide pamoate (JAN) Signifor lar (TN) SIGNIFOR LAR	Pasireotide	[4] 67, 74, 75, 77 💬 105. Growth hormone synthesis, secretion and action × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
108	Hepatitis C 💬	[1] EGFR 💬 Hepatitis C × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Hepatitis C × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 108. Hepatitis C × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
109	Hepatitis C 💬	[1] EGFR 💬 Hepatitis C × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Hepatitis C × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 108. Hepatitis C × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
110	Hepatocellular carcinoma 💬	[1] EGFR 💬 Hepatocellular carcinoma × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Hepatocellular carcinoma × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 110. Hepatocellular carcinoma × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
111	Hepatocellular carcinoma 💬	[1] EGFR 💬 Hepatocellular carcinoma × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Hepatocellular carcinoma × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 110. Hepatocellular carcinoma × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
112	HIF-1 signaling pathway 💬	[2] EGFR, ERBB2 💬 HIF-1 signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 HIF-1 signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 112. HIF-1 signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
113	HIF-1 signaling pathway 💬	[2] EGFR, ERBB2 💬 HIF-1 signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 HIF-1 signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 112. HIF-1 signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
114	Hormone signaling 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Hormone signaling × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine hydrochloride 💬 Hormone signaling × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 114. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
115	Hormone signaling 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Hormone signaling × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine 💬 Hormone signaling × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 114. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
116	Hormone signaling 💬	[3] DRD2, DRD3, DRD4 💬 Hormone signaling × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole hydrochloride 💬 Hormone signaling × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 116. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
117	Hormone signaling 💬	[3] DRD2, DRD3, DRD4 💬 Hormone signaling × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole 💬 Hormone signaling × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 116. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
118	Hormone signaling 💬	[2] DRD2, PRL 💬 Hormone signaling × Name Full Name DRD2 dopamine receptor D2 PRL prolactin	Bromocriptine mesylate 💬 Hormone signaling × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 118. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
119	Hormone signaling 💬	[2] DRD2, PRL 💬 Hormone signaling × Name Full Name DRD2 dopamine receptor D2 PRL prolactin	Bromocriptine 💬 Hormone signaling × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 118. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
120	Hormone signaling 💬	[2] DRD2, PRL 💬 Hormone signaling × Name Full Name DRD2 dopamine receptor D2 PRL prolactin	Cabergoline 💬 Hormone signaling × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 120. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
121	Hormone signaling 💬	[2] ESR1, ESR2 💬 Hormone signaling × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomiphene citrate 💬 Hormone signaling × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 121. Hormone signaling × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
122	Hormone signaling 💬	[2] ESR1, ESR2 💬 Hormone signaling × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomifene 💬 Hormone signaling × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 121. Hormone signaling × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
123	Hormone signaling 💬	[1] GHR 💬 Hormone signaling × Name Full Name GHR growth hormone receptor	Somatropin 💬 Hormone signaling × Name Other Names Somatropin Somatropin (USP/INN) Somatropin (genetical recombination) (JAN) Human growth hormone (JAN) Asellacrin (TN) Humatrope (TN) Nutropin (TN) Omnitrope (TN) GENOTROPIN HUMATROPE NORDITROPIN OMNITROPE SEROSTIM SOMATROPIN ZOMACTON	Somatotropin	[28]  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬 123. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 76 Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;Central precocious puberty;Gonadotropin producing pituitary adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 78 Hypopituitarism;Anterior pituitary hypothyroidism; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 187 Kabuki syndrome; 191 Werner syndrome; 193 Prader-Willi syndrome; 195 Noonan syndrome; 238 Vitamin D-resistant rickets;VDRR;Vitamin D-resistant osteomalacia;VDRO;FGF23-related hypophosphatemic disease;FGF23-related hypophosphatemia;Hypophosphatemic rickets/osteomalacia;Vitamin D-resistant rickets;VDRR;Hypophosphatemic rickets;Vitamin D-resistant osteomalacia;VDRO;Hypophosphatemic osteomalacia;Acquired vitamin D-resistant osteomalacia;Acquired VDRO;Tumor-induced osteomalacia;TIO; 246 Methylmalonic acidemia;MMA; 265 Lipodystrophy; 274 Osteogenesis Imperfecta; 276 Achondroplasia; 299 Cystic fibrosis;CF; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
124	Hormone signaling 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Hormone signaling × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide 💬 Hormone signaling × Name Other Names Pasireotide Pasireotide (USAN)	Pasireotide	[4] 67, 74, 75, 77 💬 124. Hormone signaling × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
125	Hormone signaling 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Hormone signaling × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide diaspartate 💬 Hormone signaling × Name Other Names Pasireotide diaspartate Pasireotide diaspartate Signifor (TN) SIGNIFOR	Pasireotide	[4] 67, 74, 75, 77 💬 124. Hormone signaling × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
126	Hormone signaling 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Hormone signaling × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide pamoate 💬 Hormone signaling × Name Other Names Pasireotide pamoate Pasireotide pamoate (JAN) Signifor lar (TN) SIGNIFOR LAR	Pasireotide	[4] 67, 74, 75, 77 💬 124. Hormone signaling × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
127	Human cytomegalovirus infection 💬	[1] EGFR 💬 Human cytomegalovirus infection × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Human cytomegalovirus infection × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 127. Human cytomegalovirus infection × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
128	Human cytomegalovirus infection 💬	[1] EGFR 💬 Human cytomegalovirus infection × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Human cytomegalovirus infection × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 127. Human cytomegalovirus infection × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
129	Human papillomavirus infection 💬	[1] EGFR 💬 Human papillomavirus infection × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Human papillomavirus infection × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 129. Human papillomavirus infection × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
130	Human papillomavirus infection 💬	[1] EGFR 💬 Human papillomavirus infection × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Human papillomavirus infection × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 129. Human papillomavirus infection × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
131	JAK-STAT signaling pathway 💬	[1] EGFR 💬 JAK-STAT signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 JAK-STAT signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 131. JAK-STAT signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
132	JAK-STAT signaling pathway 💬	[1] EGFR 💬 JAK-STAT signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 JAK-STAT signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 131. JAK-STAT signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
133	JAK-STAT signaling pathway 💬	[1] GHR 💬 JAK-STAT signaling pathway × Name Full Name GHR growth hormone receptor	Somatropin 💬 JAK-STAT signaling pathway × Name Other Names Somatropin Somatropin (USP/INN) Somatropin (genetical recombination) (JAN) Human growth hormone (JAN) Asellacrin (TN) Humatrope (TN) Nutropin (TN) Omnitrope (TN) GENOTROPIN HUMATROPE NORDITROPIN OMNITROPE SEROSTIM SOMATROPIN ZOMACTON	Somatotropin	[28]  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬 133. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 76 Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;Central precocious puberty;Gonadotropin producing pituitary adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 78 Hypopituitarism;Anterior pituitary hypothyroidism; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 187 Kabuki syndrome; 191 Werner syndrome; 193 Prader-Willi syndrome; 195 Noonan syndrome; 238 Vitamin D-resistant rickets;VDRR;Vitamin D-resistant osteomalacia;VDRO;FGF23-related hypophosphatemic disease;FGF23-related hypophosphatemia;Hypophosphatemic rickets/osteomalacia;Vitamin D-resistant rickets;VDRR;Hypophosphatemic rickets;Vitamin D-resistant osteomalacia;VDRO;Hypophosphatemic osteomalacia;Acquired vitamin D-resistant osteomalacia;Acquired VDRO;Tumor-induced osteomalacia;TIO; 246 Methylmalonic acidemia;MMA; 265 Lipodystrophy; 274 Osteogenesis Imperfecta; 276 Achondroplasia; 299 Cystic fibrosis;CF; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
134	JAK-STAT signaling pathway 💬	[1] PRL 💬 JAK-STAT signaling pathway × Name Full Name PRL prolactin	Bromocriptine mesylate 💬 JAK-STAT signaling pathway × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 134. JAK-STAT signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
135	JAK-STAT signaling pathway 💬	[1] PRL 💬 JAK-STAT signaling pathway × Name Full Name PRL prolactin	Bromocriptine 💬 JAK-STAT signaling pathway × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 134. JAK-STAT signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
136	JAK-STAT signaling pathway 💬	[1] PRL 💬 JAK-STAT signaling pathway × Name Full Name PRL prolactin	Cabergoline 💬 JAK-STAT signaling pathway × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 136. JAK-STAT signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
137	MAPK signaling pathway 💬	[2] EGFR, ERBB2 💬 MAPK signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 MAPK signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 137. MAPK signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
138	MAPK signaling pathway 💬	[2] EGFR, ERBB2 💬 MAPK signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 MAPK signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 137. MAPK signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
139	Melanoma 💬	[1] EGFR 💬 Melanoma × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Melanoma × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 139. Melanoma × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
140	Melanoma 💬	[1] EGFR 💬 Melanoma × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Melanoma × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 139. Melanoma × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
141	MicroRNAs in cancer 💬	[2] EGFR, ERBB2 💬 MicroRNAs in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 MicroRNAs in cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 141. MicroRNAs in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
142	MicroRNAs in cancer 💬	[2] EGFR, ERBB2 💬 MicroRNAs in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 MicroRNAs in cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 141. MicroRNAs in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
143	Morphine addiction 💬	[1] DRD1 💬 Morphine addiction × Name Full Name DRD1 dopamine receptor D1	Dopamine hydrochloride 💬 Morphine addiction × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 143. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
144	Morphine addiction 💬	[1] DRD1 💬 Morphine addiction × Name Full Name DRD1 dopamine receptor D1	Dopamine 💬 Morphine addiction × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 143. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
145	Neuroactive ligand signaling 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Neuroactive ligand signaling × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 145. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
146	Neuroactive ligand signaling 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Neuroactive ligand signaling × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine 💬 Neuroactive ligand signaling × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 145. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
147	Neuroactive ligand signaling 💬	[1] DRD2 💬 Neuroactive ligand signaling × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Neuroactive ligand signaling × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 147. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
148	Neuroactive ligand signaling 💬	[1] DRD2 💬 Neuroactive ligand signaling × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Neuroactive ligand signaling × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 147. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
149	Neuroactive ligand signaling 💬	[1] DRD2 💬 Neuroactive ligand signaling × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Neuroactive ligand signaling × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 149. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
150	Neuroactive ligand signaling 💬	[3] DRD2, DRD3, DRD4 💬 Neuroactive ligand signaling × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 150. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
151	Neuroactive ligand signaling 💬	[3] DRD2, DRD3, DRD4 💬 Neuroactive ligand signaling × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole 💬 Neuroactive ligand signaling × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 150. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
152	Neuroactive ligand-receptor interaction 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 152. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
153	Neuroactive ligand-receptor interaction 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4 DRD5 dopamine receptor D5	Dopamine 💬 Neuroactive ligand-receptor interaction × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 152. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
154	Neuroactive ligand-receptor interaction 💬	[3] DRD2, DRD3, DRD4 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 154. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
155	Neuroactive ligand-receptor interaction 💬	[3] DRD2, DRD3, DRD4 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 DRD4 dopamine receptor D4	Ropinirole 💬 Neuroactive ligand-receptor interaction × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 154. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
156	Neuroactive ligand-receptor interaction 💬	[2] DRD2, PRL 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD2 dopamine receptor D2 PRL prolactin	Bromocriptine mesylate 💬 Neuroactive ligand-receptor interaction × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 156. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
157	Neuroactive ligand-receptor interaction 💬	[2] DRD2, PRL 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD2 dopamine receptor D2 PRL prolactin	Bromocriptine 💬 Neuroactive ligand-receptor interaction × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 156. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
158	Neuroactive ligand-receptor interaction 💬	[2] DRD2, PRL 💬 Neuroactive ligand-receptor interaction × Name Full Name DRD2 dopamine receptor D2 PRL prolactin	Cabergoline 💬 Neuroactive ligand-receptor interaction × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 158. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
159	Neuroactive ligand-receptor interaction 💬	[1] GHR 💬 Neuroactive ligand-receptor interaction × Name Full Name GHR growth hormone receptor	Somatropin 💬 Neuroactive ligand-receptor interaction × Name Other Names Somatropin Somatropin (USP/INN) Somatropin (genetical recombination) (JAN) Human growth hormone (JAN) Asellacrin (TN) Humatrope (TN) Nutropin (TN) Omnitrope (TN) GENOTROPIN HUMATROPE NORDITROPIN OMNITROPE SEROSTIM SOMATROPIN ZOMACTON	Somatotropin	[28]  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬 159. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 76 Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;Central precocious puberty;Gonadotropin producing pituitary adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 78 Hypopituitarism;Anterior pituitary hypothyroidism; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 187 Kabuki syndrome; 191 Werner syndrome; 193 Prader-Willi syndrome; 195 Noonan syndrome; 238 Vitamin D-resistant rickets;VDRR;Vitamin D-resistant osteomalacia;VDRO;FGF23-related hypophosphatemic disease;FGF23-related hypophosphatemia;Hypophosphatemic rickets/osteomalacia;Vitamin D-resistant rickets;VDRR;Hypophosphatemic rickets;Vitamin D-resistant osteomalacia;VDRO;Hypophosphatemic osteomalacia;Acquired vitamin D-resistant osteomalacia;Acquired VDRO;Tumor-induced osteomalacia;TIO; 246 Methylmalonic acidemia;MMA; 265 Lipodystrophy; 274 Osteogenesis Imperfecta; 276 Achondroplasia; 299 Cystic fibrosis;CF; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
160	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 nuclear receptor subfamily 3 group C member 1	Dexamethasone 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexamethasone Dexamethasone (JP18/USP/INN) Decadron (TN) Maxidex (TN) DEXTENZA HEMADY MAXIDEX OZURDEX DEXAMETHASONE DEXAMETHASONE INTENSOL TAPERDEX 12-DAY TAPERDEX 6-DAY	Dexamethasone	[25] 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬 160. Neuroactive ligand-receptor interaction × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 14 Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy; 16 Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 28 Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis; 35 Pemphigus; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 81 Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency; 84 Sarcoidosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 162 Pemphigoid; 222 Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 257 Hepatic glycogenosis;Liver glycogenosis;Hepatic glycogen storage disease;Liver glycogen storage disease;Glycogen storage disease type I;GSDI;von Gierke disease;Glucose-6-phosphatase deficiency;G6Pase deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type VI;GSDVI;Hers disease;Hepatic phosphorylase deficiency;Liver phosphorylase deficiency;Glycogen storage disease type IX;GSDIX;Phosphorylase kinase deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Adult polyglucosan body disease; 296 Biliary atresia; 299 Cystic fibrosis;CF; 331 Idiopathic multicentric castleman disease;iMCD;Castleman disease;
161	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 nuclear receptor subfamily 3 group C member 1	Dexamethasone sodium phosphate 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexamethasone sodium phosphate Dexamethasone sodium phosphate (JAN/USP) Dalalone (TN) Maxidex (TN)	Dexamethasone	[25] 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬 160. Neuroactive ligand-receptor interaction × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 14 Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy; 16 Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 28 Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis; 35 Pemphigus; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 81 Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency; 84 Sarcoidosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 162 Pemphigoid; 222 Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 257 Hepatic glycogenosis;Liver glycogenosis;Hepatic glycogen storage disease;Liver glycogen storage disease;Glycogen storage disease type I;GSDI;von Gierke disease;Glucose-6-phosphatase deficiency;G6Pase deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type VI;GSDVI;Hers disease;Hepatic phosphorylase deficiency;Liver phosphorylase deficiency;Glycogen storage disease type IX;GSDIX;Phosphorylase kinase deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Adult polyglucosan body disease; 296 Biliary atresia; 299 Cystic fibrosis;CF; 331 Idiopathic multicentric castleman disease;iMCD;Castleman disease;
162	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 nuclear receptor subfamily 3 group C member 1	Dexamethasone phosphate 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexamethasone phosphate Dexamethasone phosphate Decadron-phosphate (TN)	Dexamethasone	[25] 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬 160. Neuroactive ligand-receptor interaction × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 14 Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy; 16 Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 28 Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis; 35 Pemphigus; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 63 Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 81 Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency; 84 Sarcoidosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 162 Pemphigoid; 222 Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 257 Hepatic glycogenosis;Liver glycogenosis;Hepatic glycogen storage disease;Liver glycogen storage disease;Glycogen storage disease type I;GSDI;von Gierke disease;Glucose-6-phosphatase deficiency;G6Pase deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Forbes disease;Glycogen debranching enzyme deficiency;Glycogen storage disease type VI;GSDVI;Hers disease;Hepatic phosphorylase deficiency;Liver phosphorylase deficiency;Glycogen storage disease type IX;GSDIX;Phosphorylase kinase deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Adult polyglucosan body disease; 296 Biliary atresia; 299 Cystic fibrosis;CF; 331 Idiopathic multicentric castleman disease;iMCD;Castleman disease;
163	Neuroactive ligand-receptor interaction 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Neuroactive ligand-receptor interaction × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide 💬 Neuroactive ligand-receptor interaction × Name Other Names Pasireotide Pasireotide (USAN)	Pasireotide	[4] 67, 74, 75, 77 💬 163. Neuroactive ligand-receptor interaction × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
164	Neuroactive ligand-receptor interaction 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Neuroactive ligand-receptor interaction × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide diaspartate 💬 Neuroactive ligand-receptor interaction × Name Other Names Pasireotide diaspartate Pasireotide diaspartate Signifor (TN) SIGNIFOR	Pasireotide	[4] 67, 74, 75, 77 💬 163. Neuroactive ligand-receptor interaction × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
165	Neuroactive ligand-receptor interaction 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Neuroactive ligand-receptor interaction × Name Full Name SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 SSTR3 somatostatin receptor 3 SSTR5 somatostatin receptor 5	Pasireotide pamoate 💬 Neuroactive ligand-receptor interaction × Name Other Names Pasireotide pamoate Pasireotide pamoate (JAN) Signifor lar (TN) SIGNIFOR LAR	Pasireotide	[4] 67, 74, 75, 77 💬 163. Neuroactive ligand-receptor interaction × Disease ID Name 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
166	Non-small cell lung cancer 💬	[2] EGFR, ERBB2 💬 Non-small cell lung cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Non-small cell lung cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 166. Non-small cell lung cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
167	Non-small cell lung cancer 💬	[2] EGFR, ERBB2 💬 Non-small cell lung cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Non-small cell lung cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 166. Non-small cell lung cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
168	Oxytocin signaling pathway 💬	[1] EGFR 💬 Oxytocin signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Oxytocin signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 168. Oxytocin signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
169	Oxytocin signaling pathway 💬	[1] EGFR 💬 Oxytocin signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Oxytocin signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 168. Oxytocin signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
170	Pancreatic cancer 💬	[2] EGFR, ERBB2 💬 Pancreatic cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Pancreatic cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 170. Pancreatic cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
171	Pancreatic cancer 💬	[2] EGFR, ERBB2 💬 Pancreatic cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Pancreatic cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 170. Pancreatic cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
172	Parathyroid hormone synthesis, secretion and action 💬	[1] EGFR 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 172. Parathyroid hormone synthesis, secretion and action × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
173	Parathyroid hormone synthesis, secretion and action 💬	[1] EGFR 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 172. Parathyroid hormone synthesis, secretion and action × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
174	Parkinson disease 💬	[2] DRD1, DRD2 💬 Parkinson disease × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine hydrochloride 💬 Parkinson disease × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 174. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
175	Parkinson disease 💬	[2] DRD1, DRD2 💬 Parkinson disease × Name Full Name DRD1 dopamine receptor D1 DRD2 dopamine receptor D2	Dopamine 💬 Parkinson disease × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 174. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
176	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Parkinson disease × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 176. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
177	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Parkinson disease × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 176. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
178	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Parkinson disease × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 178. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
179	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 dopamine receptor D2	Ropinirole hydrochloride 💬 Parkinson disease × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 179. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
180	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 dopamine receptor D2	Ropinirole 💬 Parkinson disease × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 179. Parkinson disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
181	Pathways in cancer 💬	[2] EGFR, ERBB2 💬 Pathways in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Pathways in cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 181. Pathways in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
182	Pathways in cancer 💬	[2] EGFR, ERBB2 💬 Pathways in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Pathways in cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 181. Pathways in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
183	Pathways in cancer 💬	[2] ESR1, ESR2 💬 Pathways in cancer × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomiphene citrate 💬 Pathways in cancer × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 183. Pathways in cancer × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
184	Pathways in cancer 💬	[2] ESR1, ESR2 💬 Pathways in cancer × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomifene 💬 Pathways in cancer × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 183. Pathways in cancer × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
185	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] EGFR 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 185. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
186	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] EGFR 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 185. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
187	Phospholipase D signaling pathway 💬	[1] EGFR 💬 Phospholipase D signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Phospholipase D signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 187. Phospholipase D signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
188	Phospholipase D signaling pathway 💬	[1] EGFR 💬 Phospholipase D signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Phospholipase D signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 187. Phospholipase D signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
189	PI3K-Akt signaling pathway 💬	[2] EGFR, ERBB2 💬 PI3K-Akt signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 PI3K-Akt signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 189. PI3K-Akt signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
190	PI3K-Akt signaling pathway 💬	[2] EGFR, ERBB2 💬 PI3K-Akt signaling pathway × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 PI3K-Akt signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 189. PI3K-Akt signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
191	PI3K-Akt signaling pathway 💬	[1] GHR 💬 PI3K-Akt signaling pathway × Name Full Name GHR growth hormone receptor	Somatropin 💬 PI3K-Akt signaling pathway × Name Other Names Somatropin Somatropin (USP/INN) Somatropin (genetical recombination) (JAN) Human growth hormone (JAN) Asellacrin (TN) Humatrope (TN) Nutropin (TN) Omnitrope (TN) GENOTROPIN HUMATROPE NORDITROPIN OMNITROPE SEROSTIM SOMATROPIN ZOMACTON	Somatotropin	[28]  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬 191. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease; 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;APS;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 76 Pituitary gonadotropin secretion hyperthyroidism;Gonadotropin secreting pituitary adenoma;Central precocious puberty;Gonadotropin producing pituitary adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 78 Hypopituitarism;Anterior pituitary hypothyroidism; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;Muscle-eye-brain disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 187 Kabuki syndrome; 191 Werner syndrome; 193 Prader-Willi syndrome; 195 Noonan syndrome; 238 Vitamin D-resistant rickets;VDRR;Vitamin D-resistant osteomalacia;VDRO;FGF23-related hypophosphatemic disease;FGF23-related hypophosphatemia;Hypophosphatemic rickets/osteomalacia;Vitamin D-resistant rickets;VDRR;Hypophosphatemic rickets;Vitamin D-resistant osteomalacia;VDRO;Hypophosphatemic osteomalacia;Acquired vitamin D-resistant osteomalacia;Acquired VDRO;Tumor-induced osteomalacia;TIO; 246 Methylmalonic acidemia;MMA; 265 Lipodystrophy; 274 Osteogenesis Imperfecta; 276 Achondroplasia; 299 Cystic fibrosis;CF; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
192	PI3K-Akt signaling pathway 💬	[1] PRL 💬 PI3K-Akt signaling pathway × Name Full Name PRL prolactin	Bromocriptine mesylate 💬 PI3K-Akt signaling pathway × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 192. PI3K-Akt signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
193	PI3K-Akt signaling pathway 💬	[1] PRL 💬 PI3K-Akt signaling pathway × Name Full Name PRL prolactin	Bromocriptine 💬 PI3K-Akt signaling pathway × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 192. PI3K-Akt signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
194	PI3K-Akt signaling pathway 💬	[1] PRL 💬 PI3K-Akt signaling pathway × Name Full Name PRL prolactin	Cabergoline 💬 PI3K-Akt signaling pathway × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 194. PI3K-Akt signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
195	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬 Prolactin signaling pathway × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomiphene citrate 💬 Prolactin signaling pathway × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 195. Prolactin signaling pathway × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
196	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬 Prolactin signaling pathway × Name Full Name ESR1 estrogen receptor 1 ESR2 estrogen receptor 2	Clomifene 💬 Prolactin signaling pathway × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 195. Prolactin signaling pathway × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
197	Prolactin signaling pathway 💬	[1] PRL 💬 Prolactin signaling pathway × Name Full Name PRL prolactin	Bromocriptine mesylate 💬 Prolactin signaling pathway × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 197. Prolactin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
198	Prolactin signaling pathway 💬	[1] PRL 💬 Prolactin signaling pathway × Name Full Name PRL prolactin	Bromocriptine 💬 Prolactin signaling pathway × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 197. Prolactin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
199	Prolactin signaling pathway 💬	[1] PRL 💬 Prolactin signaling pathway × Name Full Name PRL prolactin	Cabergoline 💬 Prolactin signaling pathway × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 199. Prolactin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
200	Prostate cancer 💬	[2] EGFR, ERBB2 💬 Prostate cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Prostate cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 200. Prostate cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
201	Prostate cancer 💬	[2] EGFR, ERBB2 💬 Prostate cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Prostate cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 200. Prostate cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
202	Proteoglycans in cancer 💬	[2] EGFR, ERBB2 💬 Proteoglycans in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Proteoglycans in cancer × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 202. Proteoglycans in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
203	Proteoglycans in cancer 💬	[2] EGFR, ERBB2 💬 Proteoglycans in cancer × Name Full Name EGFR epidermal growth factor receptor ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Proteoglycans in cancer × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 202. Proteoglycans in cancer × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
204	Proteoglycans in cancer 💬	[1] ESR1 💬 Proteoglycans in cancer × Name Full Name ESR1 estrogen receptor 1	Clomiphene citrate 💬 Proteoglycans in cancer × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 204. Proteoglycans in cancer × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
205	Proteoglycans in cancer 💬	[1] ESR1 💬 Proteoglycans in cancer × Name Full Name ESR1 estrogen receptor 1	Clomifene 💬 Proteoglycans in cancer × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 204. Proteoglycans in cancer × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
206	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Bromocriptine mesylate 💬 Rap1 signaling pathway × Name Other Names Bromocriptine mesylate Bromocriptine mesylate (USP) Bromocriptine mesilate (JP18) Parlodel (TN) BROMOCRIPTINE MESYLATE CYCLOSET	Bromocriptine	[2]  6 , 74 💬 206. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
207	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Bromocriptine 💬 Rap1 signaling pathway × Name Other Names Bromocriptine Bromocriptine (USAN/INN)	Bromocriptine	[2]  6 , 74 💬 206. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;
208	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Cabergoline 💬 Rap1 signaling pathway × Name Other Names Cabergoline Cabergoline (JP18/USP/INN) Cabaser (TN) Dostinex (TN)	Cabergoline	[4]  6 , 74, 75, 77 💬 208. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
209	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Dopamine hydrochloride 💬 Rap1 signaling pathway × Name Other Names Dopamine hydrochloride Dopamine hydrochloride (JP18/USP) Actopamin (TN) Intropin (TN) DOPAMINE HCI DOPAMINE HCI IN 5% DEXTROSE DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE DOPAMINE HYDROCHLORIDE IN DEXTROSE	Dopamine	[4]  6 ,  7 , 74, 77 💬 209. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
210	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Dopamine 💬 Rap1 signaling pathway × Name Other Names Dopamine Dopamine (INN) Medopa (TN)	Dopamine	[4]  6 ,  7 , 74, 77 💬 209. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
211	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Ropinirole hydrochloride 💬 Rap1 signaling pathway × Name Other Names Ropinirole hydrochloride Ropinirole hydrochloride (JAN/USP) Requip (TN)	Ropinirole	[3]  6 , 74, 309 💬 211. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
212	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 dopamine receptor D2	Ropinirole 💬 Rap1 signaling pathway × Name Other Names Ropinirole Ropinirole (USAN/INN) Ropitor (TN)	Ropinirole	[3]  6 , 74, 309 💬 211. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 309 Progressive myoclonus epilepsy;Unverricht-Lundborg disease;Lafora disease;Benign adult familial myoclonus epilepsy;BAFME;
213	Rap1 signaling pathway 💬	[1] EGFR 💬 Rap1 signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Rap1 signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 213. Rap1 signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
214	Rap1 signaling pathway 💬	[1] EGFR 💬 Rap1 signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Rap1 signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 213. Rap1 signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
215	Ras signaling pathway 💬	[1] EGFR 💬 Ras signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Ras signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 215. Ras signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
216	Ras signaling pathway 💬	[1] EGFR 💬 Ras signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Ras signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 215. Ras signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
217	Regulation of actin cytoskeleton 💬	[1] EGFR 💬 Regulation of actin cytoskeleton × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Regulation of actin cytoskeleton × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 217. Regulation of actin cytoskeleton × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
218	Regulation of actin cytoskeleton 💬	[1] EGFR 💬 Regulation of actin cytoskeleton × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Regulation of actin cytoskeleton × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 217. Regulation of actin cytoskeleton × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
219	Relaxin signaling pathway 💬	[1] EGFR 💬 Relaxin signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Relaxin signaling pathway × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 219. Relaxin signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
220	Relaxin signaling pathway 💬	[1] EGFR 💬 Relaxin signaling pathway × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Relaxin signaling pathway × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 219. Relaxin signaling pathway × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
221	Shigellosis 💬	[1] EGFR 💬 Shigellosis × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Shigellosis × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 221. Shigellosis × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
222	Shigellosis 💬	[1] EGFR 💬 Shigellosis × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Shigellosis × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 221. Shigellosis × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
223	Thyroid hormone signaling pathway 💬	[1] ESR1 💬 Thyroid hormone signaling pathway × Name Full Name ESR1 estrogen receptor 1	Clomiphene citrate 💬 Thyroid hormone signaling pathway × Name Other Names Clomiphene citrate Clomiphene citrate (USP) Clomifene citrate (JP18) Clomid (TN) Serophene (TN)	Clomifene	[2] 74, 77 💬 223. Thyroid hormone signaling pathway × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
224	Thyroid hormone signaling pathway 💬	[1] ESR1 💬 Thyroid hormone signaling pathway × Name Full Name ESR1 estrogen receptor 1	Clomifene 💬 Thyroid hormone signaling pathway × Name Other Names Clomifene Clomifene (INN) Clomiphene Clomifene (TN)	Clomifene	[2] 74, 77 💬 223. Thyroid hormone signaling pathway × Disease ID Name 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 77 Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
225	Tight junction 💬	[1] ERBB2 💬 Tight junction × Name Full Name ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib ditosylate 💬 Tight junction × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 225. Tight junction × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
226	Tight junction 💬	[1] ERBB2 💬 Tight junction × Name Full Name ERBB2 erb-b2 receptor tyrosine kinase 2	Lapatinib 💬 Tight junction × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 225. Tight junction × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
227	Virion - Hepatitis viruses 💬	[1] EGFR 💬 Virion - Hepatitis viruses × Name Full Name EGFR epidermal growth factor receptor	Lapatinib ditosylate 💬 Virion - Hepatitis viruses × Name Other Names Lapatinib ditosylate Lapatinib ditosylate (USAN) Lapatinib tosilate hydrate (JAN) Lapatinib ditosylate monohydrate Tykerb (TN) Tyverb (TN) TYKERB LAPATINIB	Lapatinib	[3] 34, 74, 75 💬 227. Virion - Hepatitis viruses × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;
228	Virion - Hepatitis viruses 💬	[1] EGFR 💬 Virion - Hepatitis viruses × Name Full Name EGFR epidermal growth factor receptor	Lapatinib 💬 Virion - Hepatitis viruses × Name Other Names Lapatinib Lapatinib (INN)	Lapatinib	[3] 34, 74, 75 💬 227. Virion - Hepatitis viruses × Disease ID Name 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma; 75 Cushing disease;Cushing syndrome;

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