Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Aldosterone synthesis and secretion 💬
 [1] MC2R 💬 Cosyntropin 💬 Tetracosactide [4] 83, 113, 145, 222 💬
2 Aldosterone synthesis and secretion 💬
 [1] MC2R 💬 Tetracosactide acetate 💬 Tetracosactide [4] 83, 113, 145, 222 💬
3 cAMP signaling pathway 💬
 [1] MC2R 💬 Cosyntropin 💬 Tetracosactide [4] 83, 113, 145, 222 💬
4 cAMP signaling pathway 💬
 [1] MC2R 💬 Tetracosactide acetate 💬 Tetracosactide [4] 83, 113, 145, 222 💬
5 Cortisol synthesis and secretion 💬
 [1] MC2R 💬 Cosyntropin 💬 Tetracosactide [4] 83, 113, 145, 222 💬
6 Cortisol synthesis and secretion 💬
 [1] MC2R 💬 Tetracosactide acetate 💬 Tetracosactide [4] 83, 113, 145, 222 💬
7 Cushing syndrome 💬
 [1] MC2R 💬 Cosyntropin 💬 Tetracosactide [4] 83, 113, 145, 222 💬
8 Cushing syndrome 💬
 [1] MC2R 💬 Tetracosactide acetate 💬 Tetracosactide [4] 83, 113, 145, 222 💬
9 Hematopoietic cell lineage 💬
 [1] MS4A1 💬 Rituximab 💬 Rituximab [54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
10 Hormone signaling 💬
 [1] MC2R 💬 Cosyntropin 💬 Tetracosactide [4] 83, 113, 145, 222 💬
11 Hormone signaling 💬
 [1] MC2R 💬 Tetracosactide acetate 💬 Tetracosactide [4] 83, 113, 145, 222 💬
12 Neuroactive ligand-receptor interaction 💬
 [1] MC2R 💬 Cosyntropin 💬 Tetracosactide [4] 83, 113, 145, 222 💬
13 Neuroactive ligand-receptor interaction 💬
 [1] MC2R 💬 Tetracosactide acetate 💬 Tetracosactide [4] 83, 113, 145, 222 💬
14 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Betamethasone 💬 Betamethasone [9]  2 , 28, 46, 56, 65, 83, 90, 96, 235 💬
15 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Betamethasone sodium phosphate 💬 Betamethasone [9]  2 , 28, 46, 56, 65, 83, 90, 96, 235 💬
16 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Betamethasone valerate 💬 Betamethasone [9]  2 , 28, 46, 56, 65, 83, 90, 96, 235 💬
17 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Betamethasone acetate 💬 Betamethasone [9]  2 , 28, 46, 56, 65, 83, 90, 96, 235 💬
18 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Betamethasone dipropionate 💬 Betamethasone [9]  2 , 28, 46, 56, 65, 83, 90, 96, 235 💬
19 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Betamethasone benzoate 💬 Betamethasone [9]  2 , 28, 46, 56, 65, 83, 90, 96, 235 💬
20 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Hydrocortisone 💬 Hydrocortisone [10]  6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
21 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Hydrocortisone sodium phosphate 💬 Hydrocortisone phosphate [3] 53, 81, 83 💬
22 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Hydrocortisone sodium succinate 💬 Hydrocortisone succinate [3] 81, 83, 97 💬
23 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Hydrocortisone succinate 💬 Hydrocortisone succinate [3] 81, 83, 97 💬
24 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Methylprednisolone 💬 Methylprednisolone [51]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
25 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Methylprednisolone acetate 💬 Methylprednisolone [51]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬

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