Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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1 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
CD28 [1] CD28 💬Allograft rejection
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Acazicolcept Acazicolcept 💬Allograft rejection
| Acazicolcept | 049 [1] 49 💬1. Allograft rejection
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2 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
CD80 [2] CD80, CD86 💬
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Abatacept Abatacept 💬Allograft rejection
| Abatacept | 002 [27] 2 , 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬2. Allograft rejection
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3 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
CD80 [2] CD80, CD86 💬
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Belatacept Belatacept 💬Allograft rejection
| Belatacept | 046 [1] 46 💬3. Allograft rejection
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4 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IFNG [1] IFNG 💬Allograft rejection
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Emapalumab Emapalumab 💬Allograft rejection
| Emapalumab | 049 [5] 49, 54, 60, 65, 107 💬4. Allograft rejection
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5 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IFNG [1] IFNG 💬Allograft rejection
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Fontolizumab Fontolizumab 💬Allograft rejection
| Fontolizumab | 046 [1] 46 💬5. Allograft rejection
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6 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IL10 [2] IL10, TNF 💬
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Pirfenidone Pirfenidone 💬Allograft rejection
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬6. Allograft rejection
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7 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IL12A [2] IL12A, IL12B 💬
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Ustekinumab Ustekinumab 💬Allograft rejection
| Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬7. Allograft rejection
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8 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IL5 [1] IL5 💬Allograft rejection
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Depemokimab Depemokimab 💬Allograft rejection
| Depemokimab | 044 [2] 44, 45 💬8. Allograft rejection |
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9 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IL5 [1] IL5 💬Allograft rejection
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Mepolizumab Mepolizumab 💬Allograft rejection
| Mepolizumab | 044 [4] 44, 45, 98, 162 💬9. Allograft rejection
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10 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
IL5 [1] IL5 💬Allograft rejection
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Reslizumab Reslizumab 💬Allograft rejection
| Reslizumab | 044 [2] 44, 98 💬10. Allograft rejection
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11 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
MHC1 [20] MHC1, MHC1, MHC1, MHC1, MHC1, MHC1, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬
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Glatiramer acetate Glatiramer acetate 💬Allograft rejection
| Glatiramer | 013 [3] 13, 96, 156 💬
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12 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Adalimumab Adalimumab 💬Allograft rejection
| Adalimumab | 019 [21] 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬12. Allograft rejection
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13 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Certolizumab pegol Certolizumab pegol 💬Allograft rejection
| Certolizumab pegol | 037 [7] 37, 46, 49, 96, 107, 226, 271 💬13. Allograft rejection
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14 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Etanercept Etanercept 💬Allograft rejection
| Etanercept | 015 [16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬14. Allograft rejection
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15 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Golimumab Golimumab 💬Allograft rejection
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬15. Allograft rejection
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16 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Infliximab Infliximab 💬Allograft rejection
| Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬16. Allograft rejection
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17 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Lenalidomide Lenalidomide 💬Allograft rejection
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬17. Allograft rejection
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18 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Ozoralizumab Ozoralizumab 💬Allograft rejection
| Ozoralizumab | 046 [1] 46 💬18. Allograft rejection
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19 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Pegsunercept Pegsunercept 💬Allograft rejection
| Pegsunercept | 046 [1] 46 💬19. Allograft rejection
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20 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Pomalidomide Pomalidomide 💬Allograft rejection
| Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬20. Allograft rejection
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21 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬Allograft rejection
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Thalidomide Thalidomide 💬Allograft rejection
| Thalidomide | 002 [21] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬21. Allograft rejection
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22 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNFRSF5 [1] TNFRSF5 💬Allograft rejection
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Bleselumab Bleselumab 💬Allograft rejection
| Bleselumab | 222 [1] 222 💬22. Allograft rejection
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23 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNFRSF5 [1] TNFRSF5 💬Allograft rejection
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Iscalimab Iscalimab 💬Allograft rejection
| Iscalimab | 049 [2] 49, 53 💬
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24 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNFRSF5 [1] TNFRSF5 💬Allograft rejection
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Ravagalimab Ravagalimab 💬Allograft rejection
| Ravagalimab | 046 [3] 46, 53, 97 💬
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25 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNFSF5 [1] TNFSF5 💬Allograft rejection
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Frexalimab Frexalimab 💬Allograft rejection
| Frexalimab | 013 [2] 13, 222 💬25. Allograft rejection
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26 | Allograft rejection 💬 31 genes, 26 drugs (DrugBank) and 60 diseases |
TNFSF5 [1] TNFSF5 💬Allograft rejection
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Toralizumab Toralizumab 💬Allograft rejection
| Toralizumab | 063 [1] 63 💬26. Allograft rejection
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Allograft rejection
31 genes, 26 drugs (DrugBank) and 60 diseases