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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Pancreatic secretion 💬

[2] AMY, AMY 💬

Acarbose 💬

Acarbose

[1] 298 💬

Pancreatic secretion 💬

[4] ATP1A, ATP1A, ATP1A, ATP1A 💬

Digitoxin 💬

Digitoxin

[1] 299 💬

Pancreatic secretion 💬

[4] ATP1A, ATP1A, ATP1A, ATP1A 💬

Digoxin 💬

Digoxin

[3] 8 , 46, 210 💬

Disease ID	Name
8	Huntington disease;Huntington chorea;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
210	Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome;

Pancreatic secretion 💬

[1] CA2 💬

Acetazolamide 💬

Acetazolamide

[6] 13, 90, 115, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
115	Hereditary periodic paralysis;Hereditary hypokalemic periodic paralysis;Andersen-Tawil syndrome;Hereditary hyperkalemic periodic paralysis;
155	Acquired aphasia with convulsive disorder;Landau-Kleffner syndrome;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
230	Alveolar hypoventilation syndrome;AHS;Hypoventilation syndrome;

Pancreatic secretion 💬

[1] CA2 💬

Acetazolamide sodium 💬

Acetazolamide

[6] 13, 90, 115, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
115	Hereditary periodic paralysis;Hereditary hypokalemic periodic paralysis;Andersen-Tawil syndrome;Hereditary hyperkalemic periodic paralysis;
155	Acquired aphasia with convulsive disorder;Landau-Kleffner syndrome;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
230	Alveolar hypoventilation syndrome;AHS;Hypoventilation syndrome;

Pancreatic secretion 💬

[1] CA2 💬

Dichlorphenamide 💬

Diclofenamide

[1] 114 💬

Disease ID	Name
114	Non-dystrophic myotonia syndrome;Non-dystrophic Myotonia;Myotonia congenita;Thomsen disease;Autosomal-dominant myotonia congenita;Becker disease;Autosomal-recessive myotonia congenita;Paramyotonia congenita;Sodium channel myotonia;

Pancreatic secretion 💬

[1] CA2 💬

Dorzolamide hydrochloride 💬

Dorzolamide

[1] 90 💬

Pancreatic secretion 💬

[1] CA2 💬

Dorzolamide 💬

Dorzolamide

[1] 90 💬

Pancreatic secretion 💬

[1] CA2 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

Pancreatic secretion 💬

[1] CD38 💬

Ciltacabtagene autoleucel 💬

Ciltacabtagene autoleucel

[1] 28 💬

Disease ID

Name

Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis;

Pancreatic secretion 💬

[1] CD38 💬

Daratumumab 💬

Daratumumab

[10] 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬

Disease ID	Name
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
16	Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome;
28	Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;
49	Systemic lupus erythematosus;SLE;
60	Aplastic anemia;
63	Idiopathic thrombocytopenic purpura;Primary immune thrombocytopenia;Immune thrombocytopenic purpura;
288	Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;Factor XIII deficiency;Factor VIII deficiency;Acquired hemophilia A;VWF deficiency;von Willebrand Disease;VWD;Factor V deficiency;Factor X deficiency;
331	Idiopathic multicentric castleman disease;iMCD;Castleman disease;

Pancreatic secretion 💬

[1] CD38 💬

Isatuximab 💬

Isatuximab

[3] 28, 61, 283 💬

Disease ID	Name
28	Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
283	Acquired pure red cell aplasia;Pure red cell aplasia;

Pancreatic secretion 💬

[1] CD38 💬

Mezagitamab 💬

Mezagitamab

[2] 63, 66 💬

Pancreatic secretion 💬

[1] CFTR 💬

Deutivacaftor 💬

Deutivacaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CFTR 💬

Elexacaftor 💬

Elexacaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CFTR 💬

Galicaftor 💬

Galicaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CFTR 💬

Ivacaftor 💬

Ivacaftor

[2] 299, 340 💬

Pancreatic secretion 💬

[1] CFTR 💬

Lumacaftor 💬

Lumacaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CFTR 💬

Navocaftor 💬

Navocaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CFTR 💬

Tezacaftor 💬

Tezacaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CFTR 💬

Vanzacaftor 💬

Vanzacaftor

[1] 299 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Atropine 💬

Atropine

[1] 299 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Atropine sulfate 💬

Atropine

[1] 299 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Bethanechol chloride 💬

Bethanechol

[1] 98 💬

Disease ID	Name
98	Eosinophilic gastro-intestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE;

Pancreatic secretion 💬

[1] CHRM3 💬

Blarcamesine 💬

Blarcamesine

[2] 6 , 156 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Blarcamesine hydrochloride 💬

Blarcamesine

[2] 6 , 156 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Cevimeline hydrochloride 💬

Cevimeline

[1] 53 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Cevimeline 💬

Cevimeline

[1] 53 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Chlorpromazine 💬

Chlorpromazine

[1] 254 💬

Disease ID	Name
254	Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;

Pancreatic secretion 💬

[1] CHRM3 💬

Chlorpromazine hydrochloride 💬

Chlorpromazine

[1] 254 💬

Disease ID	Name
254	Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;

Pancreatic secretion 💬

[1] CHRM3 💬

Darifenacin hydrobromide 💬

Darifenacin

[3] 2 , 13, 26 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I;HAM;

Pancreatic secretion 💬

[1] CHRM3 💬

Darifenacin 💬

Darifenacin

[3] 2 , 13, 26 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
26	HTLV-1-associated myelopathy;Tropical spastic paraparesis;HTLV-1;HTLV-I;HAM;

Pancreatic secretion 💬

[1] CHRM3 💬

Fesoterodine 💬

Fesoterodine

[1] 6 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Fesoterodine fumarate 💬

Fesoterodine

[1] 6 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Glycopyrrolate 💬

Name	Other Names
Glycopyrrolate	Glycopyrrolate (USP) Glycopyrronium bromide (JAN/INN) Cuvposa (TN) Robinul (TN) Seebri breezhaler (TN) CUVPOSA DARTISLA ODT GLYCOPYRROLATE GLYRX-PF ROBINUL GLYCATE GLYCOPYRROLATE 1ML GLYCOPYRROLATE ORAL SOLUTION

Glycopyrronium

[2] 6 , 34 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Glycopyrronium 💬

Glycopyrronium

[2] 6 , 34 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Glycopyrronium tosylate 💬

Glycopyrronium

[2] 6 , 34 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Methacholine chloride 💬

Methacholine

[1] 96 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Oxybutynin 💬

Oxybutynin

[3] 6 , 13, 53 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;

Pancreatic secretion 💬

[1] CHRM3 💬

Oxybutynin chloride 💬

Oxybutynin

[3] 6 , 13, 53 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;

Pancreatic secretion 💬

[1] CHRM3 💬

Pilocarpine 💬

Pilocarpine

[3] 6 , 53, 299 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Pilocarpine hydrochloride 💬

Name	Other Names
Pilocarpine hydrochloride	Pilocarpine hydrochloride (JP18/USP) Isopto carpine (TN) Pilopine HS (TN) Salagen (TN) Sanpilo (TN) QLOSI SALAGEN VUITY PILOCARPINE HYDRCHLORIDE PILOCARPINE HYDROCHLORIDE PILOCARPINE HYDROCHLORIDE OPHTHALMIC

Pilocarpine

[3] 6 , 53, 299 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Pilocarpine nitrate 💬

Pilocarpine

[3] 6 , 53, 299 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Propantheline bromide 💬

Propantheline

[1] 26 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Propiverine 💬

Propiverine

[1] 226 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Rocuronium bromide 💬

Rocuronium

[2] 70, 296 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Scopolamine 💬

Scopolamine

[1] 2 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Solifenacin succinate 💬

Solifenacin

[2] 6 , 13 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Solifenacin 💬

Solifenacin

[2] 6 , 13 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Tiotropium bromide hydrate 💬

Tiotropium

[3] 55, 85, 299 💬

Disease ID	Name
55	Relapsing polychondritis;
85	Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE;
299	Cystic fibrosis;CF;

Pancreatic secretion 💬

[1] CHRM3 💬

Tolterodine 💬

Tolterodine

[1] 17 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Tolterodine tartrate 💬

Tolterodine

[1] 17 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Trihexyphenidyl hydrochloride 💬

Trihexyphenidyl

[2] 5 , 6 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Trihexyphenidyl 💬

Trihexyphenidyl

[2] 5 , 6 💬

Pancreatic secretion 💬

[1] CHRM3 💬

Tropicamide 💬

Tropicamide

[1] 19 💬

Disease ID

Name

Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Kanzaki disease;Pompe disease;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Ceroid lipofuscinosis;Fabry disease;Cystinosis;

Pancreatic secretion 💬

[5] CTRB, CTRB, PRSS1_2_3, PRSS1_2_3, PRSS1_2_3 💬

Ulinastatin 💬

Ulinastatin

[2] 70, 299 💬

Pancreatic secretion 💬

[1] KCNQ1 💬

Amiodarone hydrochloride 💬

Amiodarone

[1] 127 💬

Pancreatic secretion 💬

[1] KCNQ1 💬

Amiodarone 💬

Amiodarone

[1] 127 💬

Pancreatic secretion 💬

[1] KCNQ1 💬

Ezogabine 💬

Ezogabine

[2] 2 , 144 💬

Pancreatic secretion 💬

[1] PRKCB 💬

Enzastaurin hydrochloride 💬

Enzastaurin

[1] 168 💬

Disease ID

Name

168

Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS;

Pancreatic secretion 💬

[1] PRKCB 💬

Enzastaurin 💬

Enzastaurin

[1] 168 💬

Disease ID

Name

168

Pancreatic secretion 💬

[1] SCTR 💬

Secretin 💬

Secretin human

[1] 298 💬

Pancreatic secretion 💬

[1] SLC12A2 💬

Bumetanide 💬

Bumetanide

[2] 6 , 158 💬

Pancreatic secretion 💬

[1] SLC12A2 💬

Furosemide 💬

Furosemide

[3] 6 , 77, 86 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
77	Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
86	Pulmonary arterial hypertension;PAH;