Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Phenylalanine metabolism 💬

[1] AOC3 💬

Hydralazine 💬

[1] 67 💬

2

Phenylalanine metabolism 💬

[1] DDC 💬

Benserazide 💬

[1] 6 💬

3

Phenylalanine metabolism 💬

[1] DDC 💬

[7] 6 , 13, 17, 90, 140, 164, 201 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
90	Retinitis pigmentosa;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;
201	Angelman syndrome;

4

Phenylalanine metabolism 💬

[1] HPD 💬

Nitisinone 💬

[3] 6 , 164, 241 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
164	Oculocutaneous albinism;
241	Hypertyrosinemia type I;Tyrosinemia type I;Tyrosinemia I;Hereditary tyrosinemia, Type I;Fumarylacetoacetate hydrolase deficiency;FAH deficiency;

5

Phenylalanine metabolism 💬

[1] MAOA 💬

Moclobemide 💬

[1] 6 💬

6

Phenylalanine metabolism 💬

[2] MAOA, MAOB 💬

Iproniazid 💬

[1] 6 💬

7

Phenylalanine metabolism 💬

[2] MAOA, MAOB 💬

Phenelzine 💬

[1] 6 💬

8

Phenylalanine metabolism 💬

[2] MAOA, MAOB 💬

Phentermine 💬

[1] 97 💬

9

Phenylalanine metabolism 💬

[1] MAOB 💬

Rasagiline 💬

[6] 2 , 5 , 6 , 17, 58, 66 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
58	Hypertrophic cardiomyopathy;HCM;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;

10

Phenylalanine metabolism 💬

[1] MAOB 💬

Rasagiline tartrate 💬

[6] 2 , 5 , 6 , 17, 58, 66 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
58	Hypertrophic cardiomyopathy;HCM;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;

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