Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 RIG-I-like receptor signaling pathway 💬
 [13] IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab [1] 49 💬
2 RIG-I-like receptor signaling pathway 💬
 [13] IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab [1] 49 💬
3 RIG-I-like receptor signaling pathway 💬
 [1] IFNB 💬 Dazukibart 💬 Dazukibart [1] 50 💬
4 RIG-I-like receptor signaling pathway 💬
 [2] IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
5 RIG-I-like receptor signaling pathway 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [6] 46, 49, 51, 53, 271, 300 💬
6 RIG-I-like receptor signaling pathway 💬
 [4] P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
7 RIG-I-like receptor signaling pathway 💬
 [4] P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
8 RIG-I-like receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
9 RIG-I-like receptor signaling pathway 💬
 [1] RIPK1 💬 Eclitasertib 💬 SAR443122 [1] 97 💬
10 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [21] 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
11 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [7] 37, 46, 49, 96, 107, 226, 271 💬
12 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
13 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
14 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
15 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
16 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬
17 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬
18 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
19 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
20 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [21]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬