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Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Steroid hormone biosynthesis 💬

[1] COMT 💬

Entacapone 💬

[2] 6 , 17 💬

2

Steroid hormone biosynthesis 💬

[1] COMT 💬

[1] 6 💬

3

Steroid hormone biosynthesis 💬

[1] COMT 💬

[3] 6 , 28, 127 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
28	Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Hereditary systemic amyloidosis;
127	Frontotemporal lobar degeneration;Frontotemporal dementia, behavioral abnormal type;Frontotemporal dementia;Semantic dementia;

4

Steroid hormone biosynthesis 💬

[3] CYP11A, CYP11B1, CYP17A 💬

Levoketoconazole 💬

Levoketoconazole

[1] 75 💬

5

Steroid hormone biosynthesis 💬

[1] CYP11B1 💬

Metyrapone 💬

[1] 75 💬

6

Steroid hormone biosynthesis 💬

[1] CYP11B2 💬

Osilodrostat 💬

[1] 75 💬

7

Steroid hormone biosynthesis 💬

[1] CYP11B2 💬

Osilodrostat phosphate 💬

[1] 75 💬

8

Steroid hormone biosynthesis 💬

[1] CYP17A 💬

Abiraterone acetate 💬

[2] 75, 81 💬

Disease ID	Name
75	Cushing disease;Cushing syndrome;
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

9

Steroid hormone biosynthesis 💬

[1] CYP19A 💬

Anastrozole 💬

[3] 78, 86, 193 💬

10

Steroid hormone biosynthesis 💬

[1] CYP19A 💬

[2] 81, 89 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;
89	Lymphangioleiomyomatosis;LAM;

11

Steroid hormone biosynthesis 💬

[1] HSD11B1 💬

Dipotassium glycyrrhizinate 💬

Glycyrrhizic acid

[2] 46, 51 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;

12

Steroid hormone biosynthesis 💬

[2] SRD5A1, SRD5A2 💬

Dutasteride 💬

[2] 1 , 2 💬

13

Steroid hormone biosynthesis 💬

[1] SRD5A2 💬

Finasteride 💬

[1] 6 💬