Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
4 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
5 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
6 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
7 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
12 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
13 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
16 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
17 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
18 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
19 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
20 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
21 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
22 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
23 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
24 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
25 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
26 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
27 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
28 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
29 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
30 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
31 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
32 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
33 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
34 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
35 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
36 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
37 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
38 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
39 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
40 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
41 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
42 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
43 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
44 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
45 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
46 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
47 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
48 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
49 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
50 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
51 Calcium signaling pathway 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
52 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
53 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
54 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
55 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
56 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
57 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
58 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
59 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
60 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
61 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
62 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
63 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
64 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
65 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
66 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
67 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
68 cGMP-PKG signaling pathway 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
69 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
70 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
71 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
72 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
73 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
74 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
75 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
76 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
77 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
78 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
79 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
80 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
81 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
82 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
83 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
84 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
85 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
86 Salivary secretion 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
87 Salivary secretion 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
88 Salivary secretion 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
89 Salivary secretion 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
90 Salivary secretion 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
91 Salivary secretion 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
92 Salivary secretion 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
93 Salivary secretion 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
94 Salivary secretion 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
95 Salivary secretion 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
96 Salivary secretion 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
97 Salivary secretion 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
98 Salivary secretion 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
99 Salivary secretion 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
100 Salivary secretion 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
101 Salivary secretion 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
102 Salivary secretion 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬
103 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬
104 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
105 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
106 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
107 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
108 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
109 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Ephedrine 💬 Ephedrine [1] 11 💬
110 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
111 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
112 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
113 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
114 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
115 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
116 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
117 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬
118 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
119 Vascular smooth muscle contraction 💬
 [1] ADRA1A 💬 Terazosin 💬 Terazosin [1]  6  💬

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