Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
4 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
5 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
6 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
7 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
12 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
16 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
17 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
18 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
19 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
20 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
21 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
22 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
23 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
24 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
25 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
26 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
27 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
28 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
29 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
30 Calcium signaling pathway 💬
 [1] ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
31 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
32 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
33 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
34 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
35 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
36 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
37 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
38 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
39 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
40 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
41 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
42 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
43 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
44 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
45 cGMP-PKG signaling pathway 💬
 [1] ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
46 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
47 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
48 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
49 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
50 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
51 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
52 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
53 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
54 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
55 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
56 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
57 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
58 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
59 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
60 Neuroactive ligand-receptor interaction 💬
 [1] ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
61 Salivary secretion 💬
 [1] ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
62 Salivary secretion 💬
 [1] ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
63 Salivary secretion 💬
 [1] ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
64 Salivary secretion 💬
 [1] ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
65 Salivary secretion 💬
 [1] ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
66 Salivary secretion 💬
 [1] ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
67 Salivary secretion 💬
 [1] ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
68 Salivary secretion 💬
 [1] ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
69 Salivary secretion 💬
 [1] ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
70 Salivary secretion 💬
 [1] ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
71 Salivary secretion 💬
 [1] ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
72 Salivary secretion 💬
 [1] ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
73 Salivary secretion 💬
 [1] ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
74 Salivary secretion 💬
 [1] ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
75 Salivary secretion 💬
 [1] ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬
76 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
77 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬
78 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬
79 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
80 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
81 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Ephedrine 💬 Ephedrine [1] 11 💬
82 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬
83 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬
84 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬
85 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬
86 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
87 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬
88 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
89 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬
90 Vascular smooth muscle contraction 💬
 [1] ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬

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