Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
2	AGE-RAGE signaling pathway in diabetic complications 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 AGE-RAGE signaling pathway in diabetic complications × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
3	Amyotrophic lateral sclerosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Amyotrophic lateral sclerosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
4	Apoptosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Apoptosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
5	Apoptosis - multiple species 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Apoptosis - multiple species × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
6	Autophagy - animal 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Autophagy - animal × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
7	Chemical carcinogenesis - receptor activation 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Chemical carcinogenesis - receptor activation × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
8	Cholinergic synapse 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Cholinergic synapse × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
9	Colorectal cancer 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Colorectal cancer × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
10	EGFR tyrosine kinase inhibitor resistance 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 EGFR tyrosine kinase inhibitor resistance × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
11	Endocrine resistance 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Endocrine resistance × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
12	Epstein-Barr virus infection 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Epstein-Barr virus infection × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
13	Estrogen signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Estrogen signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
14	Fluid shear stress and atherosclerosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Fluid shear stress and atherosclerosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
15	Focal adhesion 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Focal adhesion × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
16	Gastric cancer 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Gastric cancer × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
17	Hedgehog signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Hedgehog signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
18	Hepatitis B 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Hepatitis B × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
19	Herpes simplex virus 1 infection 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Herpes simplex virus 1 infection × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
20	HIF-1 signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 HIF-1 signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
21	Human immunodeficiency virus 1 infection 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Human immunodeficiency virus 1 infection × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
22	JAK-STAT signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 JAK-STAT signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
23	Lipid and atherosclerosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Lipid and atherosclerosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
24	Measles 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Measles × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
25	MicroRNAs in cancer 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 MicroRNAs in cancer × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
26	Necroptosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Necroptosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
27	Neurotrophin signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Neurotrophin signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
28	NF-kappa B signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 NF-kappa B signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
29	NOD-like receptor signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 NOD-like receptor signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
30	p53 signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 p53 signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
31	Parathyroid hormone synthesis, secretion and action 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
32	Pathways in cancer 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Pathways in cancer × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
33	Pathways of neurodegeneration - multiple diseases 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
34	PI3K-Akt signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 PI3K-Akt signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
35	Platinum drug resistance 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Platinum drug resistance × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
36	Prostate cancer 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Prostate cancer × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
37	Protein processing in endoplasmic reticulum 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Protein processing in endoplasmic reticulum × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
38	Salmonella infection 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Salmonella infection × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
39	Shigellosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Shigellosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
40	Small cell lung cancer 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Small cell lung cancer × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
41	Sphingolipid signaling pathway 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Sphingolipid signaling pathway × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
42	Toxoplasmosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Toxoplasmosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;
43	Tuberculosis 💬	[1] BCL2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name BCL2 BCL2 apoptosis regulator	Venetoclax 💬 Tuberculosis × Name Other Names Venetoclax Venetoclax (JAN/USAN/INN) Venclexta (TN)	Venetoclax	[1] 28 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 28 Systemic amyloidosis;AL amyloidosis;

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