Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Acute myeloid leukemia × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 1. Acute myeloid leukemia × Disease ID Name 34 Neurofibromatosis;
2	Acute myeloid leukemia 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Acute myeloid leukemia × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 2. Acute myeloid leukemia × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
3	Alcoholism 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Alcoholism × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 3. Alcoholism × Disease ID Name 34 Neurofibromatosis;
4	Alcoholism 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Alcoholism × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 4. Alcoholism × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
5	Alzheimer disease 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Alzheimer disease × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 5. Alzheimer disease × Disease ID Name 34 Neurofibromatosis;
6	Alzheimer disease 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Alzheimer disease × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 6. Alzheimer disease × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
7	Bladder cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Bladder cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 7. Bladder cancer × Disease ID Name 34 Neurofibromatosis;
8	Bladder cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Bladder cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 8. Bladder cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
9	Breast cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Breast cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 9. Breast cancer × Disease ID Name 34 Neurofibromatosis;
10	Breast cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Breast cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 10. Breast cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
11	cAMP signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 cAMP signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 11. cAMP signaling pathway × Disease ID Name 34 Neurofibromatosis;
12	cAMP signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 cAMP signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 12. cAMP signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
13	Chemical carcinogenesis - reactive oxygen species 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Chemical carcinogenesis - reactive oxygen species × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 13. Chemical carcinogenesis - reactive oxygen species × Disease ID Name 34 Neurofibromatosis;
14	Chemical carcinogenesis - reactive oxygen species 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Chemical carcinogenesis - reactive oxygen species × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 14. Chemical carcinogenesis - reactive oxygen species × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
15	Chemokine signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Chemokine signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 15. Chemokine signaling pathway × Disease ID Name 34 Neurofibromatosis;
16	Chemokine signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Chemokine signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 16. Chemokine signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
17	Chronic myeloid leukemia 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Chronic myeloid leukemia × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 17. Chronic myeloid leukemia × Disease ID Name 34 Neurofibromatosis;
18	Chronic myeloid leukemia 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Chronic myeloid leukemia × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 18. Chronic myeloid leukemia × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
19	Colorectal cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Colorectal cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 19. Colorectal cancer × Disease ID Name 34 Neurofibromatosis;
20	Colorectal cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Colorectal cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 20. Colorectal cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
21	Cushing syndrome 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Cushing syndrome × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 21. Cushing syndrome × Disease ID Name 34 Neurofibromatosis;
22	Cushing syndrome 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Cushing syndrome × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 22. Cushing syndrome × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
23	EGFR tyrosine kinase inhibitor resistance 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 EGFR tyrosine kinase inhibitor resistance × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 23. EGFR tyrosine kinase inhibitor resistance × Disease ID Name 34 Neurofibromatosis;
24	EGFR tyrosine kinase inhibitor resistance 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 EGFR tyrosine kinase inhibitor resistance × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 24. EGFR tyrosine kinase inhibitor resistance × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
25	Endocrine resistance 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Endocrine resistance × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 25. Endocrine resistance × Disease ID Name 34 Neurofibromatosis;
26	Endocrine resistance 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Endocrine resistance × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 26. Endocrine resistance × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
27	Endometrial cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Endometrial cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 27. Endometrial cancer × Disease ID Name 34 Neurofibromatosis;
28	Endometrial cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Endometrial cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 28. Endometrial cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
29	ErbB signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 ErbB signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 29. ErbB signaling pathway × Disease ID Name 34 Neurofibromatosis;
30	ErbB signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 ErbB signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 30. ErbB signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
31	Focal adhesion 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Focal adhesion × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 31. Focal adhesion × Disease ID Name 34 Neurofibromatosis;
32	Focal adhesion 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Focal adhesion × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 32. Focal adhesion × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
33	FoxO signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 FoxO signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 33. FoxO signaling pathway × Disease ID Name 34 Neurofibromatosis;
34	FoxO signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 FoxO signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 34. FoxO signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
35	Gastric cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Gastric cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 35. Gastric cancer × Disease ID Name 34 Neurofibromatosis;
36	Gastric cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Gastric cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 36. Gastric cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
37	Glioma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Glioma × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 37. Glioma × Disease ID Name 34 Neurofibromatosis;
38	Glioma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Glioma × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 38. Glioma × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
39	Hepatitis B 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Hepatitis B × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 39. Hepatitis B × Disease ID Name 34 Neurofibromatosis;
40	Hepatitis B 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Hepatitis B × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 40. Hepatitis B × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
41	Hepatitis C 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Hepatitis C × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 41. Hepatitis C × Disease ID Name 34 Neurofibromatosis;
42	Hepatitis C 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Hepatitis C × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 42. Hepatitis C × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
43	Hepatocellular carcinoma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Hepatocellular carcinoma × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 43. Hepatocellular carcinoma × Disease ID Name 34 Neurofibromatosis;
44	Hepatocellular carcinoma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Hepatocellular carcinoma × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 44. Hepatocellular carcinoma × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
45	Insulin signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Insulin signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 45. Insulin signaling pathway × Disease ID Name 34 Neurofibromatosis;
46	Insulin signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Insulin signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 46. Insulin signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
47	Long-term depression 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Long-term depression × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 47. Long-term depression × Disease ID Name 34 Neurofibromatosis;
48	Long-term depression 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Long-term depression × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 48. Long-term depression × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
49	Long-term potentiation 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Long-term potentiation × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 49. Long-term potentiation × Disease ID Name 34 Neurofibromatosis;
50	Long-term potentiation 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Long-term potentiation × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 50. Long-term potentiation × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
51	MAPK signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 MAPK signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 51. MAPK signaling pathway × Disease ID Name 34 Neurofibromatosis;
52	MAPK signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 MAPK signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 52. MAPK signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
53	Melanoma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Melanoma × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 53. Melanoma × Disease ID Name 34 Neurofibromatosis;
54	Melanoma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Melanoma × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 54. Melanoma × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
55	mTOR signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 mTOR signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 55. mTOR signaling pathway × Disease ID Name 34 Neurofibromatosis;
56	mTOR signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 mTOR signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 56. mTOR signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
57	Natural killer cell mediated cytotoxicity 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Natural killer cell mediated cytotoxicity × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 57. Natural killer cell mediated cytotoxicity × Disease ID Name 34 Neurofibromatosis;
58	Natural killer cell mediated cytotoxicity 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Natural killer cell mediated cytotoxicity × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 58. Natural killer cell mediated cytotoxicity × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
59	Neurotrophin signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Neurotrophin signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 59. Neurotrophin signaling pathway × Disease ID Name 34 Neurofibromatosis;
60	Neurotrophin signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Neurotrophin signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 60. Neurotrophin signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
61	Non-small cell lung cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Non-small cell lung cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 61. Non-small cell lung cancer × Disease ID Name 34 Neurofibromatosis;
62	Non-small cell lung cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Non-small cell lung cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 62. Non-small cell lung cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
63	Pancreatic cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Pancreatic cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 63. Pancreatic cancer × Disease ID Name 34 Neurofibromatosis;
64	Pancreatic cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Pancreatic cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 64. Pancreatic cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
65	Parathyroid hormone synthesis, secretion and action 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 65. Parathyroid hormone synthesis, secretion and action × Disease ID Name 34 Neurofibromatosis;
66	Parathyroid hormone synthesis, secretion and action 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 66. Parathyroid hormone synthesis, secretion and action × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
67	Pathways in cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Pathways in cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 67. Pathways in cancer × Disease ID Name 34 Neurofibromatosis;
68	Pathways in cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Pathways in cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 68. Pathways in cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
69	Pathways of neurodegeneration - multiple diseases 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 69. Pathways of neurodegeneration - multiple diseases × Disease ID Name 34 Neurofibromatosis;
70	Pathways of neurodegeneration - multiple diseases 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 70. Pathways of neurodegeneration - multiple diseases × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
71	Progesterone-mediated oocyte maturation 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Progesterone-mediated oocyte maturation × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 71. Progesterone-mediated oocyte maturation × Disease ID Name 34 Neurofibromatosis;
72	Progesterone-mediated oocyte maturation 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Progesterone-mediated oocyte maturation × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 72. Progesterone-mediated oocyte maturation × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
73	Prostate cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Prostate cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 73. Prostate cancer × Disease ID Name 34 Neurofibromatosis;
74	Prostate cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Prostate cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 74. Prostate cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
75	Proteoglycans in cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Proteoglycans in cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 75. Proteoglycans in cancer × Disease ID Name 34 Neurofibromatosis;
76	Proteoglycans in cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Proteoglycans in cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 76. Proteoglycans in cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
77	Rap1 signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Rap1 signaling pathway × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 77. Rap1 signaling pathway × Disease ID Name 34 Neurofibromatosis;
78	Rap1 signaling pathway 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Rap1 signaling pathway × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 78. Rap1 signaling pathway × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
79	Regulation of actin cytoskeleton 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Regulation of actin cytoskeleton × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 79. Regulation of actin cytoskeleton × Disease ID Name 34 Neurofibromatosis;
80	Regulation of actin cytoskeleton 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Regulation of actin cytoskeleton × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 80. Regulation of actin cytoskeleton × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
81	Renal cell carcinoma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Renal cell carcinoma × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 81. Renal cell carcinoma × Disease ID Name 34 Neurofibromatosis;
82	Renal cell carcinoma 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Renal cell carcinoma × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 82. Renal cell carcinoma × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
83	Serotonergic synapse 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Serotonergic synapse × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 83. Serotonergic synapse × Disease ID Name 34 Neurofibromatosis;
84	Serotonergic synapse 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Serotonergic synapse × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 84. Serotonergic synapse × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
85	Thyroid cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Thyroid cancer × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 85. Thyroid cancer × Disease ID Name 34 Neurofibromatosis;
86	Thyroid cancer 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Thyroid cancer × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 86. Thyroid cancer × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;
87	Vascular smooth muscle contraction 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Dabrafenib 💬 Vascular smooth muscle contraction × Name Other Names Dabrafenib Dabrafenib (USAN)	Dabrafenib	[1] 34 💬 87. Vascular smooth muscle contraction × Disease ID Name 34 Neurofibromatosis;
88	Vascular smooth muscle contraction 💬	[1] BRAF 💬 Acute myeloid leukemia × Name Full Name BRAF B-Raf proto-oncogene, serine/threonine kinase	Sorafenib 💬 Vascular smooth muscle contraction × Name Other Names Sorafenib Sorafenib (USAN/INN)	Sorafenib	[2] 34, 86 💬 88. Vascular smooth muscle contraction × Disease ID Name 34 Neurofibromatosis; 86 Pulmonary arterial hypertension;PAH;

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