Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Acute myeloid leukemia 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
3 Acute myeloid leukemia 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
4 Acute myeloid leukemia 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
5 Alcoholism 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
6 Alcoholism 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
7 Alcoholism 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
8 Alcoholism 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
9 Alzheimer disease 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
10 Alzheimer disease 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
11 Alzheimer disease 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
12 Alzheimer disease 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
13 Bladder cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
14 Bladder cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
15 Bladder cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
16 Bladder cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
17 Breast cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
18 Breast cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
19 Breast cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
20 Breast cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
21 cAMP signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
22 cAMP signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
23 cAMP signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
24 cAMP signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
25 Chemical carcinogenesis - reactive oxygen species 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
26 Chemical carcinogenesis - reactive oxygen species 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
27 Chemical carcinogenesis - reactive oxygen species 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
28 Chemical carcinogenesis - reactive oxygen species 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
29 Chemokine signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
30 Chemokine signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
31 Chemokine signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
32 Chemokine signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
33 Chronic myeloid leukemia 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
34 Chronic myeloid leukemia 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
35 Chronic myeloid leukemia 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
36 Chronic myeloid leukemia 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
37 Colorectal cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
38 Colorectal cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
39 Colorectal cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
40 Colorectal cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
41 Cushing syndrome 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
42 Cushing syndrome 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
43 Cushing syndrome 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
44 Cushing syndrome 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
45 Endometrial cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
46 Endometrial cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
47 Endometrial cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
48 Endometrial cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
49 ErbB signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
50 ErbB signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
51 ErbB signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
52 ErbB signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
53 Focal adhesion 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
54 Focal adhesion 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
55 Focal adhesion 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
56 Focal adhesion 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
57 FoxO signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
58 FoxO signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
59 FoxO signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
60 FoxO signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
61 Gastric cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
62 Gastric cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
63 Gastric cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
64 Gastric cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
65 Glioma 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
66 Glioma 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
67 Glioma 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
68 Glioma 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
69 Hepatitis B 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
70 Hepatitis B 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
71 Hepatitis B 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
72 Hepatitis B 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
73 Hepatitis C 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
74 Hepatitis C 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
75 Hepatitis C 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
76 Hepatitis C 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
77 Hepatocellular carcinoma 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
78 Hepatocellular carcinoma 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
79 Hepatocellular carcinoma 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
80 Hepatocellular carcinoma 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
81 Insulin signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
82 Insulin signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
83 Insulin signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
84 Insulin signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
85 Long-term depression 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
86 Long-term depression 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
87 Long-term depression 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
88 Long-term depression 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
89 Long-term potentiation 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
90 Long-term potentiation 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
91 Long-term potentiation 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
92 Long-term potentiation 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
93 MAPK signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
94 MAPK signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
95 MAPK signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
96 MAPK signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
97 Melanoma 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
98 Melanoma 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
99 Melanoma 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
100 Melanoma 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
101 mTOR signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
102 mTOR signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
103 mTOR signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
104 mTOR signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
105 Natural killer cell mediated cytotoxicity 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
106 Natural killer cell mediated cytotoxicity 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
107 Natural killer cell mediated cytotoxicity 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
108 Natural killer cell mediated cytotoxicity 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
109 Neurotrophin signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
110 Neurotrophin signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
111 Neurotrophin signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
112 Neurotrophin signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
113 Non-small cell lung cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
114 Non-small cell lung cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
115 Non-small cell lung cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
116 Non-small cell lung cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
117 Pancreatic cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
118 Pancreatic cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
119 Pancreatic cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
120 Pancreatic cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
121 Parathyroid hormone synthesis, secretion and action 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
122 Parathyroid hormone synthesis, secretion and action 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
123 Parathyroid hormone synthesis, secretion and action 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
124 Parathyroid hormone synthesis, secretion and action 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
125 Pathways in cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
126 Pathways in cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
127 Pathways in cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
128 Pathways in cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
129 Pathways of neurodegeneration - multiple diseases 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
130 Pathways of neurodegeneration - multiple diseases 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
131 Pathways of neurodegeneration - multiple diseases 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
132 Pathways of neurodegeneration - multiple diseases 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
133 Progesterone-mediated oocyte maturation 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
134 Progesterone-mediated oocyte maturation 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
135 Progesterone-mediated oocyte maturation 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
136 Progesterone-mediated oocyte maturation 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
137 Prostate cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
138 Prostate cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
139 Prostate cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
140 Prostate cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
141 Proteoglycans in cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
142 Proteoglycans in cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
143 Proteoglycans in cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
144 Proteoglycans in cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
145 Rap1 signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
146 Rap1 signaling pathway 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
147 Rap1 signaling pathway 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
148 Rap1 signaling pathway 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
149 Regulation of actin cytoskeleton 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
150 Regulation of actin cytoskeleton 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
151 Regulation of actin cytoskeleton 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
152 Regulation of actin cytoskeleton 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
153 Renal cell carcinoma 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
154 Renal cell carcinoma 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
155 Renal cell carcinoma 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
156 Renal cell carcinoma 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
157 Serotonergic synapse 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
158 Serotonergic synapse 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
159 Serotonergic synapse 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
160 Serotonergic synapse 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
161 Thyroid cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
162 Thyroid cancer 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
163 Thyroid cancer 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
164 Thyroid cancer 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
165 Vascular smooth muscle contraction 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
166 Vascular smooth muscle contraction 💬
 [1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
167 Vascular smooth muscle contraction 💬
 [1] BRAF 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
168 Vascular smooth muscle contraction 💬
 [1] BRAF 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬

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