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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Alcoholic liver disease 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Alcoholic liver disease 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Alcoholic liver disease 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Alcoholic liver disease 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Alcoholic liver disease 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Alcoholic liver disease 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Alcoholic liver disease 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Alcoholic liver disease 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Alcoholic liver disease 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Alcoholic liver disease 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Alcoholic liver disease 💬

[1] C5AR1 💬

Avacopan 💬

Avacopan

[4] 43, 44, 66, 222 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Complement and coagulation cascades 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Complement and coagulation cascades 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Complement and coagulation cascades 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Complement and coagulation cascades 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Complement and coagulation cascades 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Complement and coagulation cascades 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Complement and coagulation cascades 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Complement and coagulation cascades 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Complement and coagulation cascades 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Complement and coagulation cascades 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Complement and coagulation cascades 💬

[1] C5AR1 💬

Avacopan 💬

Avacopan

[4] 43, 44, 66, 222 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Coronavirus disease - COVID-19 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Coronavirus disease - COVID-19 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Coronavirus disease - COVID-19 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Coronavirus disease - COVID-19 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Coronavirus disease - COVID-19 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Coronavirus disease - COVID-19 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Coronavirus disease - COVID-19 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Coronavirus disease - COVID-19 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Coronavirus disease - COVID-19 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Coronavirus disease - COVID-19 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Coronavirus disease - COVID-19 💬

[1] C5AR1 💬

Avacopan 💬

Avacopan

[4] 43, 44, 66, 222 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Herpes simplex virus 1 infection 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Herpes simplex virus 1 infection 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Herpes simplex virus 1 infection 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Herpes simplex virus 1 infection 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Herpes simplex virus 1 infection 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Neuroactive ligand-receptor interaction 💬

[1] C5AR1 💬

Avacopan 💬

Avacopan

[4] 43, 44, 66, 222 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Neutrophil extracellular trap formation 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Neutrophil extracellular trap formation 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Neutrophil extracellular trap formation 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Neutrophil extracellular trap formation 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Neutrophil extracellular trap formation 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Neutrophil extracellular trap formation 💬

[1] C5AR1 💬

Avacopan 💬

Avacopan

[4] 43, 44, 66, 222 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Pertussis 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Pertussis 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Pertussis 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Pertussis 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Pertussis 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Pertussis 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Pertussis 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Pertussis 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Pertussis 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Pertussis 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Prion disease 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Prion disease 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Prion disease 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Prion disease 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Prion disease 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Prion disease 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Prion disease 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Prion disease 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Prion disease 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Prion disease 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Regulation of actin cytoskeleton 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Regulation of actin cytoskeleton 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

Regulation of actin cytoskeleton 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

Regulation of actin cytoskeleton 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

Regulation of actin cytoskeleton 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

Regulation of actin cytoskeleton 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

Staphylococcus aureus infection 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

Staphylococcus aureus infection 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

Staphylococcus aureus infection 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

Staphylococcus aureus infection 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

100

Staphylococcus aureus infection 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

101

Staphylococcus aureus infection 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

102

Staphylococcus aureus infection 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

103

Staphylococcus aureus infection 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

104

Staphylococcus aureus infection 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

105

Staphylococcus aureus infection 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬

106

Staphylococcus aureus infection 💬

[1] C5AR1 💬

Avacopan 💬

Avacopan

[4] 43, 44, 66, 222 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

107

Systemic lupus erythematosus 💬

[1] C5 💬

Avacincaptad pegol sodium 💬

Avacincaptad pegol

[1] 301 💬

Disease ID	Name
301	Macular dystrophy;Vitelliform macular dystrophy;Best vitelliform macular dystrophy;Best disease;Stargardt disease;Occult macular dystrophy;Cone dystrophy;Cone rod dystrophy;X-linked juvenile retinoschisis;Central areolar choroidal dystrophy;

108

Systemic lupus erythematosus 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[2] 62, 109 💬

109

Systemic lupus erythematosus 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 222 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating poly (radiculo) neuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;
222	Primary nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;

110

Systemic lupus erythematosus 💬

[1] C5 💬

Gefurulimab 💬

Gefurulimab

[1] 11 💬

111

Systemic lupus erythematosus 💬

[1] C5 💬

Nomacopan 💬

Nomacopan

[3] 62, 109, 162 💬

112

Systemic lupus erythematosus 💬

[1] C5 💬

Pozelimab 💬

Pozelimab

[3] 11, 15, 62 💬

113

Systemic lupus erythematosus 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[7] 2 , 11, 13, 50, 62, 66, 109 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

114

Systemic lupus erythematosus 💬

[1] C5 💬

Vilobelimab 💬

Vilobelimab

[3] 43, 44, 269 💬

Disease ID	Name
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;

115

Systemic lupus erythematosus 💬

[1] C5 💬

Zilucoplan sodium 💬

Zilucoplan

[2] 11, 62 💬

116

Systemic lupus erythematosus 💬

[1] C5 💬

Zilucoplan 💬

Zilucoplan

[2] 11, 62 💬