Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alzheimer disease 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Alzheimer disease × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
2	Amyotrophic lateral sclerosis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Amyotrophic lateral sclerosis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
3	Apoptosis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Apoptosis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
4	Apoptosis - multiple species 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Apoptosis - multiple species × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
5	Colorectal cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Colorectal cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
6	Endometrial cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Endometrial cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
7	Epstein-Barr virus infection 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Epstein-Barr virus infection × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
8	Hepatitis B 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Hepatitis B × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
9	Hepatitis C 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Hepatitis C × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
10	Herpes simplex virus 1 infection 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Herpes simplex virus 1 infection × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
11	Human cytomegalovirus infection 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Human cytomegalovirus infection × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
12	Human immunodeficiency virus 1 infection 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Human immunodeficiency virus 1 infection × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
13	Huntington disease 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Huntington disease × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
14	Influenza A 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Influenza A × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
15	Kaposi sarcoma-associated herpesvirus infection 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
16	Legionellosis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Legionellosis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
17	Lipid and atherosclerosis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Lipid and atherosclerosis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
18	Measles 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Measles × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
19	Non-small cell lung cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Non-small cell lung cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
20	p53 signaling pathway 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 p53 signaling pathway × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
21	Pancreatic cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Pancreatic cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
22	Parkinson disease 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Parkinson disease × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
23	Pathogenic Escherichia coli infection 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Pathogenic Escherichia coli infection × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
24	Pathways in cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Pathways in cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
25	Pathways of neurodegeneration - multiple diseases 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
26	PI3K-Akt signaling pathway 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 PI3K-Akt signaling pathway × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
27	Platinum drug resistance 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Platinum drug resistance × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
28	Prion disease 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Prion disease × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
29	Prostate cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Prostate cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
30	Small cell lung cancer 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Small cell lung cancer × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
31	Thyroid hormone signaling pathway 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Thyroid hormone signaling pathway × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
32	Toxoplasmosis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Toxoplasmosis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
33	Tuberculosis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Tuberculosis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
34	VEGF signaling pathway 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 VEGF signaling pathway × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;
35	Viral myocarditis 💬	[1] CASP9 💬 Alzheimer disease × Name Full Name CASP9 caspase 9	Rimiducid 💬 Viral myocarditis × Name Other Names Rimiducid Rimiducid (USAN/INN)	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬 1. Alzheimer disease × Disease ID Name 19 Lysosomal storage disease;Lysosomal disease; 60 Aplastic anemia; 65 Primary immunodeficiency; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 326 Osteopetrosis;

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