Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Allograft rejection 💬	[1] CD40 💬 Allograft rejection × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Allograft rejection × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 1. Allograft rejection × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
2	Allograft rejection 💬	[1] CD40 💬 Allograft rejection × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Allograft rejection × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 2. Allograft rejection × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
3	Allograft rejection 💬	[1] CD40 💬 Allograft rejection × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Allograft rejection × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 3. Allograft rejection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
4	Allograft rejection 💬	[1] CD40LG 💬 Allograft rejection × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Allograft rejection × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 4. Allograft rejection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
5	Allograft rejection 💬	[1] CD40LG 💬 Allograft rejection × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Allograft rejection × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 5. Allograft rejection × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
6	Antigen processing and presentation 💬	[1] CD4 💬 Antigen processing and presentation × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Antigen processing and presentation × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 6. Antigen processing and presentation × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
7	Antigen processing and presentation 💬	[1] CD4 💬 Antigen processing and presentation × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Antigen processing and presentation × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 7. Antigen processing and presentation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
8	Asthma 💬	[1] CD40 💬 Asthma × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Asthma × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 8. Asthma × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
9	Asthma 💬	[1] CD40 💬 Asthma × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Asthma × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 9. Asthma × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
10	Asthma 💬	[1] CD40 💬 Asthma × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Asthma × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 10. Asthma × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
11	Asthma 💬	[1] CD40LG 💬 Asthma × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Asthma × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 11. Asthma × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
12	Asthma 💬	[1] CD40LG 💬 Asthma × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Asthma × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 12. Asthma × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
13	Autoimmune thyroid disease 💬	[1] CD40 💬 Autoimmune thyroid disease × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Autoimmune thyroid disease × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 13. Autoimmune thyroid disease × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
14	Autoimmune thyroid disease 💬	[1] CD40 💬 Autoimmune thyroid disease × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Autoimmune thyroid disease × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 14. Autoimmune thyroid disease × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
15	Autoimmune thyroid disease 💬	[1] CD40 💬 Autoimmune thyroid disease × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Autoimmune thyroid disease × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 15. Autoimmune thyroid disease × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
16	Autoimmune thyroid disease 💬	[1] CD40LG 💬 Autoimmune thyroid disease × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Autoimmune thyroid disease × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 16. Autoimmune thyroid disease × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
17	Autoimmune thyroid disease 💬	[1] CD40LG 💬 Autoimmune thyroid disease × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Autoimmune thyroid disease × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 17. Autoimmune thyroid disease × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
18	Cell adhesion molecules 💬	[1] CD4 💬 Cell adhesion molecules × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Cell adhesion molecules × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 18. Cell adhesion molecules × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
19	Cell adhesion molecules 💬	[1] CD4 💬 Cell adhesion molecules × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Cell adhesion molecules × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 19. Cell adhesion molecules × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
20	Cell adhesion molecules 💬	[1] CD40 💬 Cell adhesion molecules × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Cell adhesion molecules × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 20. Cell adhesion molecules × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
21	Cell adhesion molecules 💬	[1] CD40 💬 Cell adhesion molecules × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Cell adhesion molecules × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 21. Cell adhesion molecules × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
22	Cell adhesion molecules 💬	[1] CD40 💬 Cell adhesion molecules × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Cell adhesion molecules × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 22. Cell adhesion molecules × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
23	Cell adhesion molecules 💬	[1] CD40LG 💬 Cell adhesion molecules × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Cell adhesion molecules × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 23. Cell adhesion molecules × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
24	Cell adhesion molecules 💬	[1] CD40LG 💬 Cell adhesion molecules × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Cell adhesion molecules × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 24. Cell adhesion molecules × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
25	Cytokine-cytokine receptor interaction 💬	[1] CD4 💬 Cytokine-cytokine receptor interaction × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Cytokine-cytokine receptor interaction × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 25. Cytokine-cytokine receptor interaction × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
26	Cytokine-cytokine receptor interaction 💬	[1] CD4 💬 Cytokine-cytokine receptor interaction × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Cytokine-cytokine receptor interaction × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 26. Cytokine-cytokine receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
27	Cytokine-cytokine receptor interaction 💬	[1] CD40 💬 Cytokine-cytokine receptor interaction × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Cytokine-cytokine receptor interaction × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 27. Cytokine-cytokine receptor interaction × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
28	Cytokine-cytokine receptor interaction 💬	[1] CD40 💬 Cytokine-cytokine receptor interaction × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Cytokine-cytokine receptor interaction × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 28. Cytokine-cytokine receptor interaction × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
29	Cytokine-cytokine receptor interaction 💬	[1] CD40 💬 Cytokine-cytokine receptor interaction × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Cytokine-cytokine receptor interaction × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 29. Cytokine-cytokine receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
30	Cytokine-cytokine receptor interaction 💬	[1] CD40LG 💬 Cytokine-cytokine receptor interaction × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Cytokine-cytokine receptor interaction × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 30. Cytokine-cytokine receptor interaction × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
31	Cytokine-cytokine receptor interaction 💬	[1] CD40LG 💬 Cytokine-cytokine receptor interaction × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Cytokine-cytokine receptor interaction × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 31. Cytokine-cytokine receptor interaction × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
32	Epstein-Barr virus infection 💬	[1] CD40 💬 Epstein-Barr virus infection × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Epstein-Barr virus infection × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 32. Epstein-Barr virus infection × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
33	Epstein-Barr virus infection 💬	[1] CD40 💬 Epstein-Barr virus infection × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Epstein-Barr virus infection × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 33. Epstein-Barr virus infection × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
34	Epstein-Barr virus infection 💬	[1] CD40 💬 Epstein-Barr virus infection × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Epstein-Barr virus infection × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 34. Epstein-Barr virus infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
35	Hematopoietic cell lineage 💬	[1] CD4 💬 Hematopoietic cell lineage × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Hematopoietic cell lineage × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 35. Hematopoietic cell lineage × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
36	Hematopoietic cell lineage 💬	[1] CD4 💬 Hematopoietic cell lineage × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Hematopoietic cell lineage × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 36. Hematopoietic cell lineage × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
37	Human immunodeficiency virus 1 infection 💬	[1] CD4 💬 Hematopoietic cell lineage × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Human immunodeficiency virus 1 infection × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 37. Human immunodeficiency virus 1 infection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
38	Human immunodeficiency virus 1 infection 💬	[1] CD4 💬 Hematopoietic cell lineage × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Human immunodeficiency virus 1 infection × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 38. Human immunodeficiency virus 1 infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
39	Human T-cell leukemia virus 1 infection 💬	[1] CD4 💬 Hematopoietic cell lineage × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Human T-cell leukemia virus 1 infection × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 39. Human T-cell leukemia virus 1 infection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
40	Human T-cell leukemia virus 1 infection 💬	[1] CD4 💬 Hematopoietic cell lineage × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Human T-cell leukemia virus 1 infection × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 40. Human T-cell leukemia virus 1 infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
41	Human T-cell leukemia virus 1 infection 💬	[1] CD40 💬 Human T-cell leukemia virus 1 infection × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Human T-cell leukemia virus 1 infection × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 41. Human T-cell leukemia virus 1 infection × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
42	Human T-cell leukemia virus 1 infection 💬	[1] CD40 💬 Human T-cell leukemia virus 1 infection × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Human T-cell leukemia virus 1 infection × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 42. Human T-cell leukemia virus 1 infection × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
43	Human T-cell leukemia virus 1 infection 💬	[1] CD40 💬 Human T-cell leukemia virus 1 infection × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Human T-cell leukemia virus 1 infection × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 43. Human T-cell leukemia virus 1 infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
44	Intestinal immune network for IgA production 💬	[1] CD40 💬 Human T-cell leukemia virus 1 infection × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Intestinal immune network for IgA production × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 44. Intestinal immune network for IgA production × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
45	Intestinal immune network for IgA production 💬	[1] CD40 💬 Human T-cell leukemia virus 1 infection × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Intestinal immune network for IgA production × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 45. Intestinal immune network for IgA production × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
46	Intestinal immune network for IgA production 💬	[1] CD40 💬 Human T-cell leukemia virus 1 infection × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Intestinal immune network for IgA production × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 46. Intestinal immune network for IgA production × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
47	Intestinal immune network for IgA production 💬	[1] CD40LG 💬 Intestinal immune network for IgA production × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Intestinal immune network for IgA production × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 47. Intestinal immune network for IgA production × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
48	Intestinal immune network for IgA production 💬	[1] CD40LG 💬 Intestinal immune network for IgA production × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Intestinal immune network for IgA production × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 48. Intestinal immune network for IgA production × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
49	Lipid and atherosclerosis 💬	[1] CD40 💬 Lipid and atherosclerosis × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Lipid and atherosclerosis × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 49. Lipid and atherosclerosis × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
50	Lipid and atherosclerosis 💬	[1] CD40 💬 Lipid and atherosclerosis × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Lipid and atherosclerosis × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 50. Lipid and atherosclerosis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
51	Lipid and atherosclerosis 💬	[1] CD40 💬 Lipid and atherosclerosis × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Lipid and atherosclerosis × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 51. Lipid and atherosclerosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
52	Lipid and atherosclerosis 💬	[1] CD40LG 💬 Lipid and atherosclerosis × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Lipid and atherosclerosis × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 52. Lipid and atherosclerosis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
53	Lipid and atherosclerosis 💬	[1] CD40LG 💬 Lipid and atherosclerosis × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Lipid and atherosclerosis × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 53. Lipid and atherosclerosis × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
54	Malaria 💬	[1] CD40 💬 Malaria × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Malaria × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 54. Malaria × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
55	Malaria 💬	[1] CD40 💬 Malaria × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Malaria × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 55. Malaria × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
56	Malaria 💬	[1] CD40 💬 Malaria × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Malaria × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 56. Malaria × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
57	Malaria 💬	[1] CD40LG 💬 Malaria × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Malaria × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 57. Malaria × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
58	Malaria 💬	[1] CD40LG 💬 Malaria × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Malaria × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 58. Malaria × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
59	NF-kappa B signaling pathway 💬	[1] CD40 💬 NF-kappa B signaling pathway × Name Full Name CD40 CD40 molecule	Bleselumab 💬 NF-kappa B signaling pathway × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 59. NF-kappa B signaling pathway × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
60	NF-kappa B signaling pathway 💬	[1] CD40 💬 NF-kappa B signaling pathway × Name Full Name CD40 CD40 molecule	Iscalimab 💬 NF-kappa B signaling pathway × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 60. NF-kappa B signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
61	NF-kappa B signaling pathway 💬	[1] CD40 💬 NF-kappa B signaling pathway × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 NF-kappa B signaling pathway × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 61. NF-kappa B signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
62	NF-kappa B signaling pathway 💬	[1] CD40LG 💬 NF-kappa B signaling pathway × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 NF-kappa B signaling pathway × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 62. NF-kappa B signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
63	NF-kappa B signaling pathway 💬	[1] CD40LG 💬 NF-kappa B signaling pathway × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 NF-kappa B signaling pathway × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 63. NF-kappa B signaling pathway × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
64	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] CD4 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 64. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
65	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] CD4 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 65. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
66	Primary immunodeficiency 💬	[1] CD4 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Primary immunodeficiency × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 66. Primary immunodeficiency × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
67	Primary immunodeficiency 💬	[1] CD4 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Primary immunodeficiency × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 67. Primary immunodeficiency × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
68	Primary immunodeficiency 💬	[1] CD40 💬 Primary immunodeficiency × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Primary immunodeficiency × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 68. Primary immunodeficiency × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
69	Primary immunodeficiency 💬	[1] CD40 💬 Primary immunodeficiency × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Primary immunodeficiency × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 69. Primary immunodeficiency × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
70	Primary immunodeficiency 💬	[1] CD40 💬 Primary immunodeficiency × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Primary immunodeficiency × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 70. Primary immunodeficiency × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
71	Primary immunodeficiency 💬	[1] CD40LG 💬 Primary immunodeficiency × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Primary immunodeficiency × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 71. Primary immunodeficiency × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
72	Primary immunodeficiency 💬	[1] CD40LG 💬 Primary immunodeficiency × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Primary immunodeficiency × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 72. Primary immunodeficiency × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
73	Systemic lupus erythematosus 💬	[1] CD40 💬 Systemic lupus erythematosus × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Systemic lupus erythematosus × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 73. Systemic lupus erythematosus × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
74	Systemic lupus erythematosus 💬	[1] CD40 💬 Systemic lupus erythematosus × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Systemic lupus erythematosus × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 74. Systemic lupus erythematosus × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
75	Systemic lupus erythematosus 💬	[1] CD40 💬 Systemic lupus erythematosus × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Systemic lupus erythematosus × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 75. Systemic lupus erythematosus × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
76	Systemic lupus erythematosus 💬	[1] CD40LG 💬 Systemic lupus erythematosus × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Systemic lupus erythematosus × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 76. Systemic lupus erythematosus × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
77	Systemic lupus erythematosus 💬	[1] CD40LG 💬 Systemic lupus erythematosus × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Systemic lupus erythematosus × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 77. Systemic lupus erythematosus × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
78	T cell receptor signaling pathway 💬	[1] CD4 💬 T cell receptor signaling pathway × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 T cell receptor signaling pathway × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 78. T cell receptor signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
79	T cell receptor signaling pathway 💬	[1] CD4 💬 T cell receptor signaling pathway × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 T cell receptor signaling pathway × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 79. T cell receptor signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
80	T cell receptor signaling pathway 💬	[1] CD40LG 💬 T cell receptor signaling pathway × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 T cell receptor signaling pathway × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 80. T cell receptor signaling pathway × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
81	T cell receptor signaling pathway 💬	[1] CD40LG 💬 T cell receptor signaling pathway × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 T cell receptor signaling pathway × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 81. T cell receptor signaling pathway × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
82	Th1 and Th2 cell differentiation 💬	[1] CD4 💬 Th1 and Th2 cell differentiation × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Th1 and Th2 cell differentiation × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 82. Th1 and Th2 cell differentiation × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
83	Th1 and Th2 cell differentiation 💬	[1] CD4 💬 Th1 and Th2 cell differentiation × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Th1 and Th2 cell differentiation × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 83. Th1 and Th2 cell differentiation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
84	Th17 cell differentiation 💬	[1] CD4 💬 Th1 and Th2 cell differentiation × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Th17 cell differentiation × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 84. Th17 cell differentiation × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
85	Th17 cell differentiation 💬	[1] CD4 💬 Th1 and Th2 cell differentiation × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Th17 cell differentiation × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 85. Th17 cell differentiation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
86	Toll-like receptor signaling pathway 💬	[1] CD40 💬 Toll-like receptor signaling pathway × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Toll-like receptor signaling pathway × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 86. Toll-like receptor signaling pathway × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
87	Toll-like receptor signaling pathway 💬	[1] CD40 💬 Toll-like receptor signaling pathway × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Toll-like receptor signaling pathway × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 87. Toll-like receptor signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
88	Toll-like receptor signaling pathway 💬	[1] CD40 💬 Toll-like receptor signaling pathway × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Toll-like receptor signaling pathway × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 88. Toll-like receptor signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
89	Toxoplasmosis 💬	[1] CD40 💬 Toll-like receptor signaling pathway × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Toxoplasmosis × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 89. Toxoplasmosis × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
90	Toxoplasmosis 💬	[1] CD40 💬 Toll-like receptor signaling pathway × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Toxoplasmosis × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 90. Toxoplasmosis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
91	Toxoplasmosis 💬	[1] CD40 💬 Toll-like receptor signaling pathway × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Toxoplasmosis × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 91. Toxoplasmosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
92	Toxoplasmosis 💬	[1] CD40LG 💬 Toxoplasmosis × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Toxoplasmosis × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 92. Toxoplasmosis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
93	Toxoplasmosis 💬	[1] CD40LG 💬 Toxoplasmosis × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Toxoplasmosis × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 93. Toxoplasmosis × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
94	Transcriptional misregulation in cancer 💬	[1] CD40 💬 Transcriptional misregulation in cancer × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Transcriptional misregulation in cancer × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 94. Transcriptional misregulation in cancer × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
95	Transcriptional misregulation in cancer 💬	[1] CD40 💬 Transcriptional misregulation in cancer × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Transcriptional misregulation in cancer × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 95. Transcriptional misregulation in cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
96	Transcriptional misregulation in cancer 💬	[1] CD40 💬 Transcriptional misregulation in cancer × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Transcriptional misregulation in cancer × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 96. Transcriptional misregulation in cancer × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
97	Viral life cycle - HIV-1 💬	[1] CD4 💬 Viral life cycle - HIV-1 × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Viral life cycle - HIV-1 × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 97. Viral life cycle - HIV-1 × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
98	Viral life cycle - HIV-1 💬	[1] CD4 💬 Viral life cycle - HIV-1 × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Viral life cycle - HIV-1 × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 98. Viral life cycle - HIV-1 × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
99	Viral myocarditis 💬	[1] CD40 💬 Viral myocarditis × Name Full Name CD40 CD40 molecule	Bleselumab 💬 Viral myocarditis × Name Other Names Bleselumab Bleselumab	Bleselumab	[1] 222 💬 99. Viral myocarditis × Disease ID Name 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
100	Viral myocarditis 💬	[1] CD40 💬 Viral myocarditis × Name Full Name CD40 CD40 molecule	Iscalimab 💬 Viral myocarditis × Name Other Names Iscalimab Iscalimab	Iscalimab	[2] 49, 53 💬 100. Viral myocarditis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy;
101	Viral myocarditis 💬	[1] CD40 💬 Viral myocarditis × Name Full Name CD40 CD40 molecule	Ravagalimab 💬 Viral myocarditis × Name Other Names Ravagalimab Ravagalimab	Ravagalimab	[3] 46, 53, 97 💬 101. Viral myocarditis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
102	Viral myocarditis 💬	[1] CD40LG 💬 Viral myocarditis × Name Full Name CD40LG CD40 ligand	Frexalimab 💬 Viral myocarditis × Name Other Names Frexalimab Frexalimab	Frexalimab	[2] 13, 222 💬 102. Viral myocarditis × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 222 Primary nephrotic syndrome;Nephrotic syndrome;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Membranoproliferative glomerulonephritis;MPGN;Glomerulonephritis;
103	Viral myocarditis 💬	[1] CD40LG 💬 Viral myocarditis × Name Full Name CD40LG CD40 ligand	Toralizumab 💬 Viral myocarditis × Name Other Names Toralizumab Toralizumab	Toralizumab	[1] 63 💬 103. Viral myocarditis × Disease ID Name 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
104	Virion - Human immunodeficiency virus 💬	[1] CD4 💬 Virion - Human immunodeficiency virus × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Virion - Human immunodeficiency virus × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 104. Virion - Human immunodeficiency virus × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
105	Virion - Human immunodeficiency virus 💬	[1] CD4 💬 Virion - Human immunodeficiency virus × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Virion - Human immunodeficiency virus × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 105. Virion - Human immunodeficiency virus × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
106	Yersinia infection 💬	[1] CD4 💬 Virion - Human immunodeficiency virus × Name Full Name CD4 CD4 molecule	Anti-human thymocyte immunoglobulin, rabbit 💬 Yersinia infection × Name Other Names Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit Thymoglobuline THYMOGLOBULIN	Antithymocyte immunoglobulin (rabbit)	[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬 106. Yersinia infection × Disease ID Name 13 Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 60 Aplastic anemia; 62 Paroxysmal nocturnal hemoglobinuria;PNH; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 284 Diamond-Blackfan anemia; 285 Fanconi anemia; 286 Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia; 326 Osteopetrosis;Neonatal/infantile osteopetrosis;Intermediate osteopetrosis;Delayed-onset osteopetrosis;
107	Yersinia infection 💬	[1] CD4 💬 Virion - Human immunodeficiency virus × Name Full Name CD4 CD4 molecule	Zanolimumab 💬 Yersinia infection × Name Other Names Zanolimumab Zanolimumab	Zanolimumab	[1] 46 💬 107. Yersinia infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;

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