Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 ABC transporters 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
2 ABC transporters 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
3 ABC transporters 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
4 ABC transporters 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
5 ABC transporters 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
6 ABC transporters 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
7 ABC transporters 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
8 ABC transporters 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
9 ABC transporters 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
10 ABC transporters 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
11 AMPK signaling pathway 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
12 AMPK signaling pathway 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
13 AMPK signaling pathway 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
14 AMPK signaling pathway 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
15 AMPK signaling pathway 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
16 AMPK signaling pathway 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
17 AMPK signaling pathway 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
18 AMPK signaling pathway 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
19 AMPK signaling pathway 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
20 AMPK signaling pathway 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
21 Bile secretion 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
22 Bile secretion 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
23 Bile secretion 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
24 Bile secretion 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
25 Bile secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
26 Bile secretion 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
27 Bile secretion 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
28 Bile secretion 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
29 Bile secretion 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
30 Bile secretion 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
31 cAMP signaling pathway 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
32 cAMP signaling pathway 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
33 cAMP signaling pathway 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
34 cAMP signaling pathway 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
35 cAMP signaling pathway 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
36 cAMP signaling pathway 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
37 cAMP signaling pathway 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
38 cAMP signaling pathway 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
39 cAMP signaling pathway 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
40 cAMP signaling pathway 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
41 Gastric acid secretion 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
42 Gastric acid secretion 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
43 Gastric acid secretion 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
44 Gastric acid secretion 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
45 Gastric acid secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
46 Gastric acid secretion 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
47 Gastric acid secretion 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
48 Gastric acid secretion 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
49 Gastric acid secretion 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
50 Gastric acid secretion 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
51 Pancreatic secretion 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
52 Pancreatic secretion 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
53 Pancreatic secretion 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
54 Pancreatic secretion 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
55 Pancreatic secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
56 Pancreatic secretion 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
57 Pancreatic secretion 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
58 Pancreatic secretion 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
59 Pancreatic secretion 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
60 Pancreatic secretion 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
61 Phagocytosis 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
62 Phagocytosis 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
63 Phagocytosis 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
64 Phagocytosis 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
65 Phagocytosis 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
66 Phagocytosis 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
67 Phagocytosis 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
68 Phagocytosis 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
69 Phagocytosis 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
70 Phagocytosis 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
71 Tight junction 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
72 Tight junction 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
73 Tight junction 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
74 Tight junction 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
75 Tight junction 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
76 Tight junction 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
77 Tight junction 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
78 Tight junction 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
79 Tight junction 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
80 Tight junction 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬
81 Vibrio cholerae infection 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
82 Vibrio cholerae infection 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
83 Vibrio cholerae infection 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
84 Vibrio cholerae infection 💬
 [1] CFTR 💬 Icenticaftor 💬 Icenticaftor [1] 299 💬
85 Vibrio cholerae infection 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [3] 298, 299, 340 💬
86 Vibrio cholerae infection 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
87 Vibrio cholerae infection 💬
 [1] CFTR 💬 Navocaftor 💬 Navocaftor [1] 299 💬
88 Vibrio cholerae infection 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
89 Vibrio cholerae infection 💬
 [1] CFTR 💬 Vanzacaftor 💬 Vanzacaftor [1] 299 💬
90 Vibrio cholerae infection 💬
 [1] CFTR 💬 Vanzacaftor calcium 💬 Vanzacaftor [1] 299 💬

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